Imaging spotlight: linking mechanical forces and the Golgi - News

Epithelial lumen formation is fundamental to organ development, yet how apical surfaces first emerge remains unclear. Ghosh, Martin, and Chen et al., show that lumen initiation is driven via bulk deli...

Summary: A guide to mechanics in development: unlock how forces, material properties and geometry shape the forms of life.

Quantitative comparison of morphogenesis across individuals remains a fundamental challenge, as developing embryos vary in shape, orientation and developmental tempo. Moreover, real-time three-dimensi...

Samara Ranie, PhD student in Melanie White's lab, takes us through a day in the life of a transgenic quail lab.

The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...

New webinar series on cell migration - News

Nuclear deformation and mechano-signalling are regulated by the coupling of vimentin cytoskeleton to the extracellular matrix through fibrillar adhesions, modulating the timescale of mechanotransducti...

Mechanical forces shape the developing heart by controlling cell volume through a Piezo1-driven hydraulic mechanism.