Steven Kleinstein @skleinstein.bsky.social · 01/10/2026Submit your abstract for the 2027 Immcantation Users Group Meeting. Deadline is TODAY! 001
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 28/09/2026🚨 Immcantation users, don't forget to submit your 250-word abstract by October 1st! 👉 Find the template, submission instructions, and registration form here: immcantation.github.io/users-meetin... #immunosky 023
Steven Kleinstein @skleinstein.bsky.social · 28/09/2026🚨 immcantation.org user or interested in #Bcell repertoire analysis? 🗓️Join the FREE virtual 2027 Immcantation Users Group Meeting 📅 Jan 21, 2027 ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2026 🔗 immcantation.github.io/users-meetin... 000
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 20/08/2026Save the Date:📅 1/21/27 10-1:30PM (ET). We’re excited to announce the upcoming FREE virtual 2027 Immcantation Users Group Meeting. Stay tuned for updated information, including registration, agenda, and abstract submission deadlines. immcantation.github.io/users-meetin... #immunosky 021
Reposted by Steven KleinsteinEric Topol @erictopol.bsky.social · 05/08/2026Severe Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...nature.comVirus reactivation in acute and long COVID-19 - NatureChronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog... 9444210
Reposted by Steven KleinsteinYale Pathology @yalepathology.bsky.social · 01/04/2026Congratulations to Cole Jensen, MPH, a PhD Student in Computational Biology & Bioinformatics and a member of the @skleinstein.bsky.social Lab at @yalemedicine.bsky.social, on being chosen for a prestigious National Institutes of Health (NIH) F31 Award bit.ly/4bWbFtB 021
Reposted by Steven KleinsteinAIRR-Community @airr-community.bsky.social · 27/02/2026🚀 Registration is now OPEN for AIRR Community Meeting VIII: Decoding and Recoding Immunity! Join us June 8–11, 2026 at Yale University (USA) or attend virtually. 💸 Early-bird rates available until April 15! 🔗 Register: tinyurl.com/airrcmeeting8 #AIRRC8 #immunoskytinyurl.comAIRR Community Meeting VIII. 155
Reposted by Steven KleinsteinSteven Kleinstein @skleinstein.bsky.social · 07/01/2026Immcantation.org user or interested in #Bcell & #Tcell repertoire analysis? #AIRRseq 🚨Register now for the "2026 Immcantation Users Group Meeting" 🗓️FREE virtual meeting on January 22, 2026 from 10AM – 1:30PM ET. 🔗Program & registration: immcantation.github.io/users-meetin... 065
Steven Kleinstein @skleinstein.bsky.social · 07/01/2026Immcantation.org user or interested in #Bcell & #Tcell repertoire analysis? #AIRRseq 🚨Register now for the "2026 Immcantation Users Group Meeting" 🗓️FREE virtual meeting on January 22, 2026 from 10AM – 1:30PM ET. 🔗Program & registration: immcantation.github.io/users-meetin... 065
Steven Kleinstein @skleinstein.bsky.social · 31/10/2025Interested in pursuing a PhD in Computational Biology and Biomedical Informatics (CBB) at Yale? Join us for a CBB PhD Virtual Open House Tuesday, November 11 | 8:00–9:00 PM ET 👉 Register here: yalesurvey.ca1.qualtrics.com/jfe/form/SV_... @yalecbb.bsky.social 051
Reposted by Steven KleinsteinArmita Nourmohammad @thearmita.bsky.social · 27/10/2025excited to announce that this January we are relocating to Yale to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI): @yalecsei.bsky.social looking to hire 2 postdocs to join us in this endeavor. more details can be found here: sites.google.com/uw.edu/statp...sites.google.comSPE - join usPostdoctoral position: In January 2026, we are relocating to Yale university to start a theory initiative at the Center for Systems and Engineering Immunology (CSEI). We are looking for talented postd... 1218
Steven Kleinstein @skleinstein.bsky.social · 16/10/2025Interested in pursuing a PhD in Computational Biology and Biomedical Informatics (CBB) at Yale? Join us for the CBB PhD Virtual Open House Tuesday, October 21 | 8:00–9:00 PM ET 👉 Register here: yalesurvey.ca1.qualtrics.com/jfe/form/SV_... @yalecbb.bsky.social 041
Steven Kleinstein @skleinstein.bsky.social · 01/10/2025TODAY is the deadline for abstract submission for the 2026 Immcantation Users Group Meeting! immcantation.github.io/users-meetin...immcantation.github.io2026 Immcantation Users Group Meeting 010
Steven Kleinstein @skleinstein.bsky.social · 24/09/2025🚨 Immcantation.org user or interested in #Bcell repertoire analysis? 🗓️ Join the FREE virtual 2026 Immcantation Users Group Meeting 📅 Jan 22, 2026 | ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2025 🔗 immcantation.github.io/users-meeting/2026 #AIRRseq #Immcantation 042
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 24/09/2025🚨 One week left! 🚨 Don’t forget to submit your 250-word abstract by October 1st! Share how you use Immcantation and contribute to building a supportive, collaborative research community. 🔗 2026 Immcantation Users Group Meeting immcantation.github.io/users-meeting/2026 #airrseq #immunosky 043
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 28/08/2025🚨 Immcantation.org user or interested in #Bcell repertoire analysis? 🗓️ Join the FREE virtual 2026 Immcantation Users Group Meeting 📅 Jan 22, 2026 | ⏰ 10AM–1:30PM ET 📢 Abstracts due Oct 1, 2025 🔗 immcantation.github.io/users-meeting/2026 #AIRRseq #Immcantation 065
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 15/06/2025Our condolences to family and friends of our long collaborator Atul Butte. Word of his death came from Euan Ashley of @stanfordmedicine.bsky.social #memorial www.linkedin.com/posts/euanas...linkedin.comAtul Butte died yesterday. | Euan AshleyAtul Butte died yesterday. The world lost a giant. A big bear of a man. With a huge smile. With love for everyone. With energy that could power a room. I loved everything about Atul. I loved how he wa... 061
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 02/06/2025Our collaborators @camilahcoelho.bsky.social @vivianasimonlab.bsky.social (+ others) show that monovalent XBB.1.5 vaccines recall mostly cross-reactive antibodies to ancestral SARS-CoV-2, not robust de novo responses. @lancetmicrobe.bsky.social #ImmuneSky www.thelancet.com/journals/lan...thelancet.comMapping of human monoclonal antibody responses to XBB.1.5 COVID-19 monovalent vaccines: a B cell analysisOur findings offer key molecular insights into whether strain-specific boosters elicit sufficient protection against SARS-CoV-2 emerging variants. This knowledge can inform decisions on booster design... 066
Reposted by Steven KleinsteinProf. Akiko Iwasaki @virusesimmunity.bsky.social · 10/05/2025Next week, we are hosting an international scientific workshop focused on the pathogenesis of #LongCovid at @yalemed.bsky.social. Please join us on May 15th to learn about what we know and what we need to investigate next to get to the root causes to accelerate therapies 👇🏼👇🏼 918466
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 06/05/2025Don’t forget! 🌺🧪 Our HIPC symposium is happening tomorrow — join us for a great lineup of talks from @bjoernpeters.bsky.social, @lungdrc.bsky.social, @settelab.bsky.social, Victoria Zyulina & Thomas Hagan Tues May 6th | 8:30-10:30 am | Room 313C #Immunology #AAI2025 #HIPC 063
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 23/04/2025Come get our #immune data, free #FAIRsharing is at @immportdb.bsky.social - from @columbiauniversity.bsky.social @icahn.bsky.social @yalemedicine.bsky.social @stanfordimmunology.bsky.social @benaroyaresearch.bsky.social @lji.org MIT, Seattle Children's #AAI2025 #ImmuneSky #IDsky 054
Reposted by Steven KleinsteinDavid van Dijk @vandijklab.bsky.social · 18/04/2025What if LLMs could “read” & “write” biology? 🤔 Introducing C2S‑Scale—a Yale and Google collab: we scaled LLMs (up to 27B!) to analyze & generate single‑cell data 🧬 ➡️ 📝 🔗 Blog: research.google/blog/teachin... 🔗 Preprint: biorxiv.org/content/10.1...research.googleTeaching machines the language of biology: Scaling large language models for next-generation single-cell analysis 21810
Reposted by Steven KleinsteinEric Topol @erictopol.bsky.social · 18/04/2025Below, from earlier today, confirmed @statnews.com www.statnews.com/2025/04/18/n...statnews.comNIH said to have halted awarding of new grants to more top universitiesUniversities whose NIH funding has been frozen may face further strain as the agency holds off awarding new grants to at least a half dozen of them, according to an internal email. 1321997
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 03/04/2025Exciting news!! We are happy to announce that we will have a HIPC Symposium at @aai.org on Tues, May 6th. HIPC will also have a Super Booth at #AAI2025 along with @iedb.bsky.social and the iAKC Project. Check out the full Symposia list, and see you there! 🔗: immunology2025.aai.org/guest-sympos...immunology2025.aai.orgGuest Symposia - IMMUNOLOGY2025™Information and details about Guest Symposia to be presented at IMMUNOLOGY2025™! 065
Reposted by Steven KleinsteinMichelle Linterman @linterman.bsky.social · 17/03/2025Great to have our latest review "The cellular factors that impair the germinal center in advanced age" out @jimmunol.bsky.social. Work led by @wsfoster.bsky.social and Edith Marcial-Juárez. With @sanmarti92.bsky.social creating the beautiful GC images in figure 2. doi.org/10.1093/jimm... 03711
Reposted by Steven KleinsteinStand Up for Science! @standupforscience.net · 02/03/2025WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025 7722481152
Reposted by Steven KleinsteinStand Up for Science! @standupforscience.net · 21/02/2025🚨☀️ Hey Bluesky! Know anyone near the following cities that would be willing to help us Stand Up for Science? ☀️🚨 Annapolis, MD Bismarck, ND Boise, ID Charleston, WV Dover, DE Jackson, MS Anchorage or Juneau, AK Montpelier, VT Richmond, VA Send them our way! #standupforscience2025 25411213
Reposted by Steven KleinsteinStand Up for Science! @standupforscience.net · 12/02/2025Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence 289114575402
Reposted by Steven KleinsteinScience Magazine @science.org · 19/02/2025Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. So far, they have attracted more than 100 volunteers from some 30 states who are hoping to rally support for research as a public good. scim.ag/4328LADscim.ag‘I really wanted something to happen.’ The students behind the Stand Up for Science protestsNew group hopes to turn out researchers for 7 March demonstrations against Trump administration policies 2723360
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 19/02/2025Presentations from the 2025 Immcantation Users Group Meeting are now available on the Immcantation YouTube channel! Thank you to our speakers and participants! www.youtube.com/playlist?lis... #immcantation #airrseq #immunoskyyoutube.com2025 Immcantation Users Group Meeting - YouTubeThe 2025 Immcantation Users Group Meeting (https://immcantation.github.io/users-meeting/2025/index.html) took place on January 30th, 2025. It served as a vir... 021
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 19/02/2025Our collaborators identify multi-omic factor that predicts #LongCovid Among 50+ authors include @sesmalab.bsky.social @joanndarce.bsky.social @bjoernpeters.bsky.social @slimfourati.bsky.social @droferlevy.bsky.social @leying2024.bsky.social #IDsky #MedSky www.biorxiv.org/content/10.1...biorxiv.orgIdentification of a multi-omics factor predictive of long COVID in the IMPACC studyFollowing SARS-CoV-2 infection, ∼10-35% of COVID-19 patients experience long COVID (LC), in which often debilitating symptoms persist for at least three months. Elucidating the biologic underpinnings ... 152
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 17/02/2025Our collaborators @rgottardo.bsky.social and Ken Stuart (+ others) describe tagtango, an application to compare #single-cell annotations. #bioinformatics academic.oup.com/bioinformati...academic.oup.comtagtango: an application to compare single-cell annotationsAbstractSummary. In this article, we present tagtango, an innovative R package and web application designed for robust and intuitive comparison of single-c 043
Reposted by Steven KleinsteinThe Daily Pub @thedailypub.bsky.social · 13/01/2025Unlocking new insights with nipalsMCIA. This tool speeds up data analysis for big datasets by clustering and visualizing info faster than before. Check it out for both bulk and single cell data on Bioconductor with how-to guides and extras online.doi.orgnipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares.Published in Bioinformatics (Oxford, England) 051
Reposted by Steven KleinsteinbioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 10/06/2024nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares www.biorxiv.org/content/10.1101/202… biorxiv.orgnipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares https://www.biorxiv.org/content/10.1101/2024.06.07.597819v1 Motivation: With the increased reliance on multi-omics data for bulk and single cell analyses, the a 011
Steven Kleinstein @skleinstein.bsky.social · 30/01/2025Interested in B cell receptor repertoire analysis? We have a great set of speakers lined up for the “2025 Immcantation Users Group Meeting!” Check out the UPDATED program and register for this free virtual meeting taking place on 1/30/25 10AM-1:40PM (ET) at: immcantation.github.io/users-meetin... 021
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 29/01/2025Don’t miss the “2025 Immcantation Users Group Meeting” on 1/30/25 10AM-1:40PM (ET) to learn how AIRR-seq can be used to study infection, vaccination, clonal lineages, and more. **UPDATED PROGRAM** and registration: immcantation.github.io/users-meetin... #immcantation #AIRRseq #immunosky #immunology 011
Steven Kleinstein @skleinstein.bsky.social · 17/01/2025Looking forward to hearing from the great speakers lined up for the “2025 Immcantation Users Group Meeting!” Check out the program and register for this free virtual meeting 1/30/25 10AM-1:40PM (ET) at: immcantation.github.io/users-meetin... @immcantation.bsky.social 065
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 27/12/2024Find some of our over 50 investigators in Starter Pack. If you are one in our collaboration - please reply OR write a DM to @rgottardo.bsky.social to ask to be added. (Know you need adding - @camilacoelho.bsky.social and @joanndarce.bsky.social ) bsky.app/starter-pack... 021
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 05/12/2024Investigators, if your name does not appear on the Starter Pack of HIPC investigators, please send a message to @rgottardo.bsky.social and ask to be added, or write a reply to him. We will be reminding you about this in meetings in the next few weeks. bsky.app/starter-pack... 031
Reposted by Steven Kleinsteinfanofactor 🧬💻 @fanofactor.bsky.social · 16/12/2024Immcantation.org user or interested in B cell repertoire analysis? Register now for “2025 Immcantation Users Group Meeting”. FREE virtual meeting 1/30/25 10AM-1:40PM (ET). Info at: immcantation.github.io/users-meetin... #immcantation #AIRRseq #immunosky 052
Reposted by Steven KleinsteinHIPC @hipcproject.bsky.social · 11/12/2024Our collaborators designed an #immune health metric, a way of calculating the state of the #system. Study from earlier this year. Authors include @tsanglab.bsky.social @skleinstein.bsky.social #IDSky #MedSky @naturemedicine.bsky.social www.nature.com/articles/s41...nature.comA unified metric of human immune health - Nature MedicineA multimodal analysis of patients with 22 different immune-mediated monogenic diseases versus matched healthy controls leads to the development of the immune health metric, which could be implemented ... 073
Reposted by Steven KleinsteinDr Debbie Burnett @debburnett.bsky.social · 03/12/2024I’ve tried to put together a starter pack of immunologists/scientists exploring B Cell Repertoires and Antibody Affinities. Please feel free to share/join! go.bsky.app/4P64DmM 56626
Reposted by Steven KleinsteinPaul Thomas @pgtimmune.bsky.social · 26/11/2024ALSO! We are hiring for the last open position (Bioinformatics Research Scientist) in the TIRTL group! Love coding, math, robotics, and uncovering the immune system's secrets? You know you do, so join us! (stjude.wd1.myworkdayjobs.com/stjude/job/M...).stjude.wd1.myworkdayjobs.comBioinformatics Research Scientist (TIRTL Bluesky)The Bioinformatics Research Scientist is responsible for designing, developing, improving, modifying, and operating data analysis pipelines. Manages projects and coordinates other efforts related to a... 11511
Reposted by Steven KleinsteinRaphael Gottardo @rgottardo.bsky.social · 25/11/2024Thanks @tsanglab.bsky.social for putting this together! #immunology #datascience go.bsky.app/PjH2Fuj 03210
Reposted by Steven KleinsteinRaphael Gottardo @rgottardo.bsky.social · 24/11/2024Ok, I tried to create my own list of people working on developing statistical or machine learning models applied to omics data. I am sure I missed a lot of cool people. If you'd like to be added, let me know. #Stats #ML #Omics go.bsky.app/73rcuJn 389536
Reposted by Steven KleinsteinKim Good-Jacobson @kimljacobson.bsky.social · 16/11/2024Save the date! It may be a while to go yet, but I’m very excited for our B-cellapalooza in 2026! 1439
Reposted by Steven KleinsteinJamie Heather @jamieheather.bsky.social · 18/11/2024Inspired by @rodrahimi.bsky.social 's noble efforts linking immunologists together over here, let's try and get more specifically TCR/BCR/AIRR/repertoire chat going with this starter park go.bsky.app/Gi2dcGd Drop me a beep to get added or suggest others! 217029
Steven Kleinstein @skleinstein.bsky.social · 20/11/2024Are you an Immcantation.org user or interested in B cell repertoire analysis? Register now for the 2025 Immcantation Users Group Meeting! The meeting will feature talks from users showcasing how they use Immcantation in their research. Info and registration at: immcantation.github.io/users-meetin...immcantation.orgImmcantation: An Integrated Framework for Adaptive Immune Receptor Repertoire AnalysisImmcantation: An Integrated Framework for Adaptive Immune Receptor Repertoire Analysis 0159