A Labour leader is out of control. The world needs a containment strategy now

The US giants would love to stop battling each other and be protected from China – and they might have hit on just the narrative to make that possible, writes our tech columnist

Naturalists' Notebooks: a treasure trove

Single-cell sequencing (SCS) techniques have the potential to offer precise insights into cellular diversity by revealing unique genetic and transcriptomic p...

This tutorial overviews the use of organoid technologies across a broad spectrum of applications, from investigating cell fate decisions and cell–cell interactions to studying genetic diseases, specie...

This perspective summarizes early experiences from genomic newborn screening studies, totaling over 10,800 infants from the US, Belgium, and Australia. While these provide data on technical feasibilit...

Newcastle Hospitals is among five centres using a rapid new test of brain tumour diagnosis.

The test means patients can start treatment sooner and are spared weeks of uncertainty.

YouTube video by Sunderland AFC

CLIMB is a cloud computing infrastructure for microbial bioinformatics — notebook servers, shared storage and reproducible workflows for genomics, metagenomics and pathogen surveillance researchers ac...

Background Spatial transcriptomics enables high-resolution profiling of gene expression within tissue slices, but its reliability is often compromised by technical batch effects that obscure biologica...

Abstract. The rapid advancement of single-cell technologies has significantly enhanced our ability to investigate cellular heterogeneity within plant tissu

Author summary Spatial transcriptomics (ST) lets researchers measure gene expression while preserving the tissue location of each measurement. Where a cell sits, and which cells surround it, shape how...

In this Perspective, Gemma Whyatt and Jodi Whitehouse—two women living with the rare condition Congenital Melanocytic Naevus—outline why lived experience must shape rare disease research from the outs...

Feed the microbiome, repair the gut

In this Review, Buckley et al. discuss how DNA methylation is interpreted in mammals and plants, focusing on the reader proteins and transcription factors that bind to methylated DNA and the downstrea...

YouTube video by Denis Prokopyev

Background Ultra-multiplex PCR has become essential for targeted amplicon sequencing in molecular biology and clinical genetics. Methods We implemented PCRpanel, a command-line Java application with a...

Background The ability to capture cellular dynamics at high spatial and molecular resolution is crucial for understanding complex biological processes, including development, tissue remodeling, and di...

Cell-free DNA (cfDNA), released from apoptotic and necrotic cells into body fluids, is a non-invasive source of genetic information for disease prediction, diagnosis, and monitoring. However, its low ...

Large networks are particularly beneficial to researchers in under-represented groups.