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Roman Stetsenko

@romanstet.bsky.social
237 followers 243 following 10 posts

Evolutionary biologist interested in the population genetics and genomics of selfing organisms. Post-doc at Uni. of Edinburgh.

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Reposted by Roman Stetsenko
Stephanie Lamy @stephlamy.bsky.social · 07/10/2026
For my ENG speaking followers Unprecedented High School blockades began in the outskirts of Paris in Créteil on the 21st of Sept. National mobilisations followed on the 29th of September, the 1st and the 6th of October. The movement is ongoing and has spread both in scope and scale. #tippingpoint
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Will Ratcliff @wcratcliff.bsky.social · 07/10/2026
Out today in @nature.com: our review on how single cells evolve into multicellular organisms. With Ozan Bozdag, @kaitong25.bsky.social, Peter Yunker, and @matthewherron.bsky.social. rdcu.be/9ZuiKow9twKa For an overview, check out the video below.
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Parul Johri @johriparul.bsky.social · 08/10/2026
We asked what variation might look like in microbial/pathogenic populations that undergo recurrent bottlenecks while invading hosts. We used the coalescent to build a model that incorporates within- and between-host evolution using a metapopulation framework: www.biorxiv.org/content/10.6...
biorxiv.org
A model for within- and between-host evolution in pathogens
Many pathogenic and microbial species undergo complex life cycles wherein they experience drasrtic bottlenecks during invasion into a host and rapid growth within hosts. The effects of such a complex ...
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Débora Y C Brandt @deboraycb.bsky.social · 08/10/2026
Now that it's officially out, I have to say I'm quite proud of this work🙂 I got involved in it after a bit of a failure in another proj. Took way longer than it could. Started pregnant, published close to baby's 3rd bday😅 Very grateful for my patient mentors and collaborators doi.org/10.1093/molb...
academic.oup.com
Characterizing the detectable and invisible fractions of genomic loci under balancing selection
Abstract. Balancing selection refers to scenarios where selection maintains genetic polymorphisms affecting fitness and its components. Empirical studies h
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Aida Andres @aidaandres.bsky.social · 08/10/2026
The latest from us on balancing selection, now in final version in MBE @molbioevol.bsky.social @official-smbe.bsky.social 🧬 🧪 #Popgen #EvolutionaryBiology
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Max Reuter @maxreuter.bsky.social · 07/10/2026
Our paper on detecting (or not) balancing selection is now out, in all its typeset beauty, in the October issue of @molbioevol.bsky.social: academic.oup.com/mbe/article/...
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Kevin @kevinlikesmaps.bsky.social · 26/09/2026
US media largely is not covering a story about Russia blockading a Ukrainian city and starving them to death. They have to eat weeds and dogs. Ukraine can't evacuate them or get humanitarian aid to them. This is what occupation looks like. This is why Ukraine cannot give up.
bbc.com
Oleshky: Eating garden weeds to survive in Russian-occupied city cut off from food and water
The BBC has spoken to residents in the Russian-occupied Ukrainian town of Oleshky who say they are being "constantly shelled".
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Louis Witter @louiswitter.com · 25/09/2026
Un homme, mort, gisant dans l’eau après avoir tenté de traverser la Manche pour trouver refuge au Royaume-Uni. Cette image a été prise par le photojournaliste Sameer Al-Doumi sur la plage d’Hardelot, en France, il y a deux jours. Dans l’indifférence. www.instagram.com/p/DdqjKYZDVH...
Dans la mer, à une dizaine de mètres du rivage, on voit le dos et les jambes d’un homme face contre mer, avec une vague qui lui passe dessus.
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 11/09/2026
The effects of supergene evolution on the structure and stability of the G-matrix www.biorxiv.org/content/10.64898/20…
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 24/09/2026
Selfing-aware demographic inference highlights local population structure and bottlenecks in Hawaiian Caenorhabditis elegans www.biorxiv.org/content/10.64898/20…
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Laura Ross @laurarossevo.bsky.social · 08/09/2026
Ever wondered why diverse organism shrink their genome in specific cells? We try to make sense of these curious cases of programmed DNA elimination in a review that came out today @naturerevgenet.bsky.social trebuchet.public.springernature.app/get_content/... @sandraduharcourt.bsky.social
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Evolution Letters @evolletters.bsky.social · 31/08/2026
Recombination helps evolution—but it can also cause mutations. New theory shows that even small increases in mutation near crossovers can oppose the evolution of higher recombination rates. By @sarperotto.bsky.social and Bret Payseur academic.oup.com/evlett/advan...
academic.oup.com
Elevated mutation near crossovers inhibits the evolution of recombination
Abstract. Recombination diversifies offspring genomes and helps ensure chromosome segregation during meiosis. Mutation rates are elevated near crossovers d
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KamilSJaron.bsky.social @kamilsjaron.bsky.social · 18/09/2026
I am so excited to see this preprint out. I started working on springtails with @laurarossevo.bsky.social in 2019, but this pinnacle of our efforts manifested only with heroric leadership of Sam Ebdon! So, what's the deal? 👇
Globular springtail Allacma fusca. Female, one of the samples in the linked preprint.
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Laura Ross @laurarossevo.bsky.social · 10/09/2026
My lab @ Edinburgh university is recruiting a postdoc to work on the weird and wonderful germline-specific chromosomes of flies. elxw.fa.em3.oraclecloud.com/hcmUI/Candid... collaboration with @germline.bsky.social and yukiko yamashita funded by @novonordisk.bsky.social please repost!
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Joelle Lafond, PhD @joellelafond.bsky.social · 08/09/2026
🚨Our new preprint is out! 🤩 🌟 Mutation rates vary widely across taxa, and decades of research have sought to explain why. ♀️♂️ Reproductive modes, and evolutionary shifts between them, could help explain some of this variation. ❓ So what does the evidence tell us? 👀 Read our preprint to find out!
doi.org
Reproductive mode and the evolution of mutation rate
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Stephanie Lamy @stephlamy.bsky.social · 08/09/2026
🚨 Qui est avec moi? 📣 Exclure @delogusebastien.bsky.social de @lfi.bsky.social & garantir les droits économiques de toutes les mères solo Allez on signe ✍️ et on partage ♻️ ! www.change.org/StopViolence...
change.org
Signez la pétition
Exclure Sébastien Delogu de LFI & garantir les droits économiques de toutes les mères solo
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Gemma Murray @gemmamurray.bsky.social · 04/09/2026
I’m hiring two postdocs to join my group at UCL, both funded for 3 years, to investigate how commensal bacteria contribute to the evolution and spread of antimicrobial resistance in pathogens. Please share! Links below 👇 www.jobs.ac.uk/job/DSU266/r... www.jobs.ac.uk/job/DSU268/r...
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UNITED24 Media @united24media.com · 02/09/2026
🕯️ Kyiv is mourning 25-year-old paramedic Yeva Roiter, killed in a Russian double-tap strike while saving lives. An artist and an art historian, she worked in game dev before dedicating herself to evacuating the wounded and aiding animals. 📷: hromadske
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PLOS Biology @plosbiology.org · 30/08/2026
Why do some #bacteria #evolve #antibiotic resistance more readily than others? This study shows that naturally occurring single nucleotide polymorphisms in the PhoQP system change how readily E. coli evolves trimethoprim resistance and which mutations enable it. 🧪 #AcademicSky plos.io/4qCDXQM
Proposed model for the contribution of polymorphisms towards evolvability of resistance, and the role of fitness cost of TMP resistance in determining the optimal level of PhoQ activity during evolution.
A: Polymorphisms influence evolvability under drug pressure if they have epistatic interactions with adaptive mutations. Positive epistasis between pre-existing polymorphisms and adaptive mutations promotes the evolution of resistance, i.e., enhances evolvability of resistance. In contrast, negative epistasis diminishes evolvability. In addition, polymorphisms with negative epistasis can also drive adaptation to antibiotics through novel mutational paths. B: PhoQP signalling pathway across different mutants from the present study. The impact of PhoQ activity on trimethoprim resistance due to DHFR expression is correlated with fitness cost due to RpoS cross-activation. Genetic variation in the pathway is brought about by naturally occurring polymorphisms or drug-selected adaptive mutations. These genetic changes in the pathway activate signalling to different extents at the molecular level, thereby altering global transcriptome to different extents. Scaling of trimethoprim resistance level and fitness cost leads to changes in the concentration of antibiotic required to select for different levels of PhoQ/PhoP pathway activity. The presence of a hypersensitising allele of DHFR drove E. coli towards a high activity, high cost PhoQ mutant demonstrating how polymorphisms can change the mutational landscape of adaptation to antibiotics
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Roman Stetsenko @romanstet.bsky.social · 26/08/2026
Je te l’ai envoyé par email 🙂
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UNITED24 Media @united24media.com · 24/08/2026
Russia has tried to take Ukraine's independence away by force for years. It has failed. Ukraine is still here. Still free. Still fighting.
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 23/08/2026
Self-fertilization reverses the direction of selection on recombination www.biorxiv.org/content/10.64898/20…
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Charles Mullon @charlesmullon.bsky.social · 19/08/2026
With @ewanflintham.bsky.social @thomaslesaffre.bsky.social and @sarperotto.bsky.social we've been thinking about what theory tells us about sexual antagonism (SA = when selection favours different trait values in females and males). Our review is here: tinyurl.com/ct5mk8mv
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Ina Satokangas @inasatok.bsky.social · 20/08/2026
The last paper from my PhD is out in Molecular Ecology. We looked at genomic divergence and introgression across a young species group of five Formica wood ant species 🐜🐜🐜🐜🐜. My favourite result: Introgression was not strongly positively correlated with recombination rate!
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Jeremy Yoder says no war @jbyoder.org · 19/08/2026
What has population genomics told us about the dynamics of selection and plant adaptation? doi.org/10.1093/molb...
doi.org
What has population genomics told us about the dynamics of selection and plant adaptation?
Abstract. Population genomics has transformed our understanding of how natural selection shapes plant genomes. The explosion of whole-genome resequencing d
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Molecular Biology and Evolution @molbioevol.bsky.social · 18/08/2026
McQueen, Yang & Wittkopp show that epistatic interactions between new mutations and as little as one nucleotide change impacting gene regulation can alter the distribution of mutational effects on gene expression. 🔗 doi.org/10.1093/molb... #societyjournal #evobio #molbio
doi.org
Epistatic impacts of cis- and trans-regulatory mutations on the distribution of mutational effects for gene expression in Saccharomyces cerevisiae
Abstract. Epistasis can influence evolution by causing the distribution of phenotypic effects for new mutations to vary among genotypes. Here, we investiga
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 15/08/2026
The evolution of context-specific dominance during selective sweeps www.biorxiv.org/content/10.64898/20…
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Jørgen Heszlein @heszlein.bsky.social · 12/08/2026
New estimate of Elon Musk’s death toll just dropped www.thelancet.com/journals/lan...
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Вікіпедія @ukwiki.bsky.social · 13/08/2026
Написали 🤓 uk.wikipedia.org/wiki/Редуплікація
uk.wikipedia.org
Редуплікація — Вікіпедія
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Emmanuel Chastellière @gillossen.bsky.social · 12/08/2026
Les exemplaires sont arrivés ! 🎉 Ma traduction de la novella de @annaleen.bsky.social débarque chez Nouveaux Millénaires le 26 août. 🍜🤖 #BookSky
Des exemplaires de la VF d'Automatic Noodle, intitulée Le restaurant des robots rêveurs, dans un bol avec des baguettes. L'illustration est identique à la VO et le tout est posé sur un bureau "bois".
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Graham Coop @gcbias.bsky.social · 12/08/2026
Excited for @gabrielesgarlata.bsky.social’s new preprint on the Genome-Wide Effect of Drift and Selection over a Single Generation 1/n www.biorxiv.org/content/10.6...
biorxiv.org
The Genome-Wide Effect of Drift and Selection over a Single Generation
The relative importance of genetic drift versus selection to evolutionary change has long been debated. This debate has mainly focused over long-time-scales (e.g. hundreds of thousands of generations)...
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CNRS Écologie & Environnement @cnrsecologie.bsky.social · 05/08/2026
#RésultatScientifique🔎 Une étude publiée dans la revue Palaeo3 révèle une diversité inattendue d’interactions entre plantes et arthropodes dans les forêts tropicales du bassin du Nord-Pas-de-Calais, il y a plus de 300 millions d’années. ➡️ www.inee.cnrs.fr/fr/cnrsinfo/...
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Thomas Lesaffre 🌱 @thomaslesaffre.bsky.social · 03/08/2026
Job opening at @dee-unil.bsky.social 🇨🇭! I have had the privilege to work as a postdoc at the DEE for the last five years. It is a fantastic place to work at, filled with great researchers in an amazing environment surrounded by mountains 🏔️ and beautiful Léman. I highly recommend applying!
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Peter Price @petedp.bsky.social · 29/07/2026
📣 Searching for a PostDoc! 📣 Soon to be moving to San Sebastian, Spain, as @georgiamneuro.bsky.social starts her new position 🎉. Looking for a remote/hybrid position within ecoevo. Broad interests in sexual selection, mutation rates, genomic conflicts and gametogenesis. Get in touch!
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Alex Mackintosh @thymelicus.bsky.social · 19/07/2026
New preprint on the effect of ancient admixture / structure on genealogical trees. I introduce a new way of summarising reconstructed genealogies that captures a clear signal of ancient gene flow into the ancestors of modern humans. Feedback welcome!
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Jeff Groh @jeffgroh.bsky.social · 28/07/2026
Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...
pnas.org
Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS
In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...
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Josselin Clo @josselin-clo.bsky.social · 28/07/2026
The third Ph.D. chapter of Diane Douet is online on BioRxiv. Diane investigated the probability of maintaining sporophytic self-incompatibility systems in diploid vs tetraploid populations. Congratulations, Diane! www.biorxiv.org/content/10.6...
biorxiv.org
Breakdown of sporophytic self-incompatibility: Diploids versus tetraploids
Many angiosperm species possess self-incompatibility (SI) systems that prevent self-fertilization. Because empirical studies often report higher selfing rates in tetraploids than in diploids, we inves...
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Quentin Bacquelé @quentinbacquele.bsky.social · 23/07/2026
1/ The world's songbirds sing in just 8 basic sounds. And where a bird lives decides which ones it uses. My first PhD paper is out now in @science.org (www.science.org/doi/10.1126/science.aee6239) Here is what we found:
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Mayor Zohran Kwame Mamdani @mayor.nyc.gov · 22/07/2026
Benjamin Netanyahu is a war criminal.
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 20/07/2026
Evolutionary regimes determine the accuracy of epistasis inference from temporal genetic data www.biorxiv.org/content/10.64898/20…
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Romeo Kokriatski @vagrantjourno.bsky.social · 16/07/2026
Good morning. Protests are breaking out all over Ukraine today, to oppose the dismissal of Mykhailo Fedorov from the post of defense minister. He was appointed six months ago, and had been to have rapidly introduced wide-ranging reforms to the ministry and the military.
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 03/07/2026
Differential selection between sexes and the evolution of recombination in haplodiploids www.biorxiv.org/content/10.64898/20…
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Stefano Bettinazzi @stefanobettinazzi.bsky.social · 08/07/2026
How far do intergenomic compatibility shape ageing trajectories? 🦠🧬🪰 Our latest study in PNAS @pnas.org, explores this. Check it out! doi.org/10.1073/pnas... Thanks to an amazing team: @fcamus.bsky.social, @dk-dowling.bsky.social, Avi & Finley. #mitochondria #mitonuclear #ageing #diet #hormesis
doi.org
Mitonuclear discordance modulates mitochondrial ageing dynamics in natural Drosophila populations | PNAS
Mitochondrial decline is a hallmark of ageing, yet the role of intergenomic compatibility in shaping ageing trajectories remains poorly understood,...
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Kevin @kevinlikesmaps.bsky.social · 09/07/2026
Yuri Khimich - Khreshchatyk (main street in central Kyiv) - 1969 #UkrArt #УкрАрт
a brightly colored painting of a wide tree-lined city street from above, with cars and trams
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Marie Monniaux @mariemonniaux.bsky.social · 08/07/2026
That seems like a very useful list!
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Mario Vallejo-Marin @nicrodemo.bsky.social · 06/07/2026
PhD Position at Uppsala University. Sophie Karrenberg’s Lab. the project is about sex chromosome evolution in plants. Come join us! Deadline 22 July. www.uu.se/en/about-uu/...
uu.se
PhD position in evolutionary genomics - Uppsala University
PhD position in evolutionary genomics, Department of Ecology and Genetics, Uppsala University
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Leeban Yusuf @leebanhy.bsky.social · 06/07/2026
How do coevolutionary interactions begin in nature, and what are the first steps of reciprocal adaptation? Our preprint investigates these questions in a natural experiment: an introduced cricket (T. oceanicus) and its acoustically hunting parasitoid (O. ochracea) in Hawaii. shorturl.at/7llsA 1/n
shorturl.at
Ecological genomics of a novel host-parasitoid arms-race in nature
Novel antagonistic interactions between species are expected to drive especially rapid coevolution. However, little is known about the genomic basis of such coevolution in nature because novel inter-s...
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@steffrichard73.bsky.social 💙💛🦈🌻🍉🦝🚜✊🇺🇦 @steffrichard73.bsky.social · 06/07/2026
For how long do we say what @nicolastenzer.bsky.social wrote below ! What are we waiting for, with our air defenses systems and missiles in our warehouses ? The fall of 🇺🇦 ? More dead & wounded ? More destructions ? No politics in 🇪🇺 can consider himself as a leader ! I When you don't have the 🧵
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Randall Munroe @xkcd.com · 03/07/2026
Holes xkcd.com/3266/
Comic: Holes. Elevation is to scale relative to sea level and ground level. Land shapes and horizontal distances are not to scale. [Lines for every 1k meters starting from -12k up to +4k: Bingham Canyon Mine (US), Veryovkina Cave (Georgia), MPONENG Gold Mine (South Africa), Sanford Laboratory (US), Giant Crystal Cave (Mexico), Derinkugo Underground City (Turkey), WIPP (US), Restof Salt Mine, with an arrow pointing at the bottom that reads “oops” (US), San Andreas Fault Observatory Borehole (US) CFB North Bay (Canada), Woodingdean Water Well (dug by hand) (United Kingdom), Diefen-Bunker (Canada), Deep Underground Command Center (Canceled in 1965) (US), Lake Peigneu, with another oops arrow next to it (US), Sydney Opera House Parking (Australia), Onkalo Spent Nuclear Fuel Repository (Finland), Hudson River, Delaware Aqueduct (US), Raven Rock (US), Wieliczka and Bochina Salt Mines (Poland), Atchison Storage Facility (US), Snolab (Canada), Detroit Salt Mine (US), Hongyancun Subway Station (China), Nuclear Test Shafts (North Korea), Super Kamiokande Neutrino Detector (Japan), Gran Sasso Laboratory (Italy), Peak above Gran Sasso, Modane Laboratory (France), Peak above Modane Laboratory, Gotthard Tunnel (Switzerland), Peak above Cheyenne Bunker and Gotthard Tunnel, Cheyenne Mountain Bunker (US), Kola Superdeep Borehole (Russia) - deepest artificial point below surface at -11917m, Lake Baikal (Russia), sediments under Lake Baikal, IDDP-2 Borehole (Iceland), Dead Sea (multiple countries), Ryfylke Tunnel (Norway), Pantal Remis Mine with another oops arrow (Malaysia), Great Blue Hole (Belize), Joides Resolution Expedition 307 (Atlantic Ocean), Deepwater Horizon Borehole (Gulf of Mexico) - deepest artificial point below sea level at -11944m, Glomar Challenger Hole 504B (Pacific Ocean), Mohole (Pacific Ocean), Joides Resolution Expedition 329 (Pacific Ocean), Mariana Trench (Pacific Ocean)]
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Nandita Garud @nanditagarud.bsky.social · 30/06/2026
We are very excited to share our latest. We thought that soft sweeps would be the only type of sweep spreading across human gut microbiomes. Turns out many are hard! Reach @peterlaurin.bsky.social 's thread on why! And tomorrow at #SMBE2026 I will share this work and more!
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