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Stefano Bettinazzi

@stefanobettinazzi.bsky.social

300 followers 291 following 20 posts

BBSRC Fellow at University College London. Soft spot for mitochondria, intergenomic coevolution, heteroplasmy, and adaptation 🦠🧬🐝🪰☀️. MSCA Alumnus and happy dad. 🇮🇹🇨🇦🇬🇧

Posts Replies Media

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 08/07/2026

How far do intergenomic compatibility shape ageing trajectories? 🦠🧬🪰 Our latest study in PNAS @pnas.org, explores this. Check it out! doi.org/10.1073/pnas... Thanks to an amazing team: @fcamus.bsky.social, @dk-dowling.bsky.social, Avi & Finley. #mitochondria #mitonuclear #ageing #diet #hormesis

Mitonuclear discordance modulates mitochondrial ageing dynamics in natural Drosophila populations | PNAS

Mitochondrial decline is a hallmark of ageing, yet the role of intergenomic compatibility in shaping ageing trajectories remains poorly understood,...

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 18/06/2026

Incredibly grateful for the opportunity and support from BBSRC @ukri.org. Looking forward to start exploring intra-individual mtDNA variation in bees at UCL 🧬🦠🐝 @fcamus.bsky.social @cloeucl.bsky.social @ucllifesciences.bsky.social www.ukri.org/news/bbsrc-i...

BBSRC invests in 21 new Fellows

BBSRC invests £10 million in 21 new Fellows as part of its ongoing commitment to develop the next generation of independent research leaders across the UK.

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 18/06/2026

It was a real pleasure talking about mito-adaptation at the EED Seminar at QMUL @qmulsbbs.bsky.social earlier this week. So many nice colleagues and interesting researches going on there. Looking forward to meet again.

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 02/06/2026

Thrilled to share I’ve been awarded a @ukri.org BBSRC Fellowship at UCL @cloeucl.bsky.social 🎉 to investigate extreme mitochondrial heteroplasmy in bees 🦠🧬🐝. Exciting times ahead!!

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 13/05/2026

🎉New postdoc position! 🎉 Come and join a wonderful lab!!!

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Stefano Bettinazzi @stefanobettinazzi.bsky.social · 01/04/2026

Our latest study on mitochondrial heteroplasmy and its impact on energy metabolism across sexes is finally out in ProcB @royalsocietypublishing.org!! 🎉🦪🧬 Kudos to Ariane and the Breton Lab for this marvellous work. #mitochondria #heteroplasmy #metabolism Check it out! doi.org/10.1098/rspb...

Metabolic consequences of naturally occurring mitochondrial heteroplasmy in bivalves

Abstract. Oxidative phosphorylation, the cornerstone of mitochondrial energy production, is a tightly regulated process that relies on the strict interacti

Reposted by Stefano Bettinazzi

Journal of Evolutionary Biology @jevbio.bsky.social · 22/01/2026

RESEARCH ARTICLE: Early diet leaves a lasting mark! Mismatched mitochondrial + nuclear genes slow fly development & shift adult food choices. G×E shape metabolism & behaviour: doi.org/10.1093/jeb/... @stefanobettinazzi.bsky.social et al. (2025) @fcamus.bsky.social @dk-dowling.bsky.social

Mitonuclear interactions and early-life diet shape adult nutritional behaviour

Abstract. Mitochondrial function relies on close coordination between the mitochondrial and nuclear genomes. Disruption to this coordination—via mitonuclea

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 20/10/2025

Hot of the press #mitochondria paper!! 🎉 @jevbio.bsky.social New evidence that #mitonuclear discordance and early-life #diet jointly shape development and adult behaviour in #Drosophila. 🪰🦠🧬🍝 @fcamus.bsky.social @dk-dowling.bsky.social et al., academic.oup.com/jeb/advance-...

academic.oup.com

Mitonuclear interactions and early-life diet shape adult nutritional behaviour

Abstract. Mitochondrial function relies on close coordination between the mitochondrial and nuclear genomes. Disruption to this coordination—via mitonuclea

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 27/09/2025

Over grateful to have been part of this wonderful mito session at #EDRC2025. Lovely discussion panel afterwards. Big thanks to the organisers Tiina, Laura and Yuliya, as well as the other presenters. 🪰🧬🦠

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 24/09/2025

Arrived in Alicante! 🇪🇸☀️ Getting ready for what will surely be a great #EDRC2025 conference! Plenty of mitochondria talks too. 🦠🧬🪰

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 04/08/2025

New Evolution-Digest out! 🎉 Intergenomic discordance should reduce fitness, especially in older males. Well, @martingarlovsky.bsky.social et al., showed that it might not always be the case. 🪰 @sse-evolution.bsky.social

academic.oup.com

Digest: Sex-specific benefits of mitochondrial introgression

Abstract. Disrupting mitochondrial and nuclear coadaptation is expected to reduce fitness, especially in males and with age. But is that always true? Garlo

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 14/07/2025

It has been a great #SEB2025 conference in Antwerp. Lovely to see so many old (and new!) friends and attend wonderful talks. Also very grateful to have been able to present my late work on mito-nuclear coevolution and ageing. Such a wonderful event 🪰🧬🇧🇪 @sebiology.bsky.social .See you next year!

Reposted by Stefano Bettinazzi

Shaun Killen @shaunkillen.bsky.social · 16/12/2024

Our recent study, led by @marie-levet.bsky.social, shows that while temperature impacts cells & whole-body function, parasites mainly affect overall metabolism. Analyses from whole-animal to tissues and enzyme activities. Great work Marie! @stefanobettinazzi.bsky.social doi.org/10.1111/1365...

Reposted by Stefano Bettinazzi

Hansi Weissensteiner @whansi.bsky.social · 20/11/2024

I just created a starter pack to collect accounts related to mtDNA research. Feel free to contact me if I should put someone on the list go.bsky.app/BiCguQz

Reposted by Stefano Bettinazzi

Michael Landis @landismj.bsky.social · 03/12/2024

Here's the second starter pack of Early Career Evolutionary Biologists: go.bsky.app/j5DX3f Link to first starter pack: go.bsky.app/MzND7nX Follow these inspirational folks to support the next generation of evolutionary biologists #evobio Out of time for now! Will add more names this weekend

Screen shot of starter pack image

Reposted by Stefano Bettinazzi

Biological Journal of the Linnean Society @biojlinnsoc.bsky.social · 02/12/2024

Ever wondered if anything determines the mitochondrial DNA you end up inheriting? Check out this recent paper to find out!

Reposted by Stefano Bettinazzi

Florent Waltz @florentwaltz.bsky.social · 18/11/2024

Trying to gather all the mitochondriacs that landed here Help me fill up this starter pack! Just ask and i'll add you 🤓 #Mitochondria #Mitochondriacs #Respiration #Organelle go.bsky.app/G1DPArc

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 01/12/2024

Congrats to Ariane and Thierry for their wonderful job, examining the link between variation in MMP and paternal inheritance of mitochondria. @biojlinnsoc.bsky.social #sophiebretonlab #mitochondria doi.org/10.1093/biol...

Investigating the role of mitochondrial membrane potential in paternal inheritance of mitochondria

Abstract. The process of oxidative phosphorylation (OXPHOS) in mitochondria depends on an electrochemical gradient known as the mitochondrial membrane pote

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 01/12/2024

How could we use mitochondrial physiology in a conservation context? 🦠🐝🐠🪲🦜 Happy to see this synthesis of SEB2023 conference published in @conphysjournal.bsky.social. Thanks to the team: Elisa, Neal and Enrique. doi.org/10.1093/conp...

An evolving roadmap: using mitochondrial physiology to help guide conservation efforts

Mitochondrial processes play crucial roles in species’ responses to environmental variation. Here, we synthesize the methods and approaches involved in mit

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 01/12/2024

New collaborative work led by @marie-levet.bsky.social finally out in @funecology.bsky.social! 🎉 Here we examined the combined impact of parasite infection and temperature on fish metabolism. 🐟🪱🦠🌡️. Marvellous team with Sandra, Vincent, Shaun and Sophie. doi.org/10.1111/1365...

Acclimation temperature and parasite infection drive metabolic changes in a freshwater fish at different biological scales

Read the free Plain Language Summary for this article on the Journal blog.

Stefano Bettinazzi @stefanobettinazzi.bsky.social · 01/12/2024

🎉New paper out!🎉 @evolletters.bsky.social Interested in #mitochondria and how #mitonuclear compatibility shapes fitness in insect populations? Check this out! 🦠🪰 A big thanks to all the authors: @fcamus.bsky.social @dk-dowling.bsky.social, Enrique, Nick, Marion et al #MSCA doi.org/10.1093/evle...

Assessing the role of mitonuclear interactions on mitochondrial function and organismal fitness in natural Drosophila populations

Abstract. Mitochondrial function depends on the effective interactions between proteins and RNA encoded by the mitochondrial and nuclear genomes. Evidence

Reposted by Stefano Bettinazzi

Evolution Letters @evolletters.bsky.social · 29/08/2024

Could intergenomic compatibility shape fitness in insect populations? doi.org/10.1093/evle... Now in @evolletters.bsky.social by Stefano Bettinazzi et al.

Assessing the role of mitonuclear interactions on mitochondrial function and organismal fitness in natural Drosophila populations

Abstract. Mitochondrial function depends on the effective interactions between proteins and RNA encoded by the mitochondrial and nuclear genomes. Evidence