Theory-guided experiments reveal single-cell heterogeneity of lysis-associated bacteriophage traits from population scale data.

A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.

A veces, quienes menos esperamos que “hablen” tienen mucho que decir, como es el caso de los virus que se comunican entre sí para decidir si es el momento idóneo de infectar a una bacteria o si convie...

Nature Microbiology, Published online: 27 May 2026; doi:10.1038/s41564-026-02355-xThe prophage of a clinical Enterobacter isolate uses an RNA-guided transcription factor to alter flagellar composition, leading to enhanced bacterial motility and improved gut colonization in a mouse model.

The life cycle of temperate bacteriophages involves lytic or lysogenic cycles and has historically served as a model for studying genetic regulation. This Review provides an updated overview of these ...

Prophages are pervasive in the human gut yet largely overlooked in microbiome research, despite substantial functional potential. Emerging evidence indicates that prophages regulate bacterial fitness,...

As the British naturalist celebrates a milestone birthday, we take a look at how his work has shaped science.

Browser-based prophage prediction using PhiSpy, Pyodide, and WebAssembly

Nature Reviews Microbiology, Published online: 23 April 2026; doi:10.1038/s41579-026-01306-xComprehensive assessment of the host range of phages is a prerequisite for their safe and effective use in multiple applications but is rarely undertaken. This Review outlines the molecular and ecological determinants of phage host range and discusses the importance of these determinants for developing phage-based applications.

The LTP database compiling 16S rRNA gene sequences of all type strains of Bacteria and Archaea has served taxonomists for two decades. Here we report the LTPlus, a manually curated and aligned databas...

Gallego-del-Sol et al. show that arbitrium-coding phages can sense non-cognate peptide signals from other phages to regulate lysis-lysogeny decisions. This crosstalk affects lysis-lysogeny outcomes of...

Bacteriophages (phages) are emerging as programmable biological therapeutics in oncology, extending beyond their traditional antimicrobial applications. This review proposes a phage–microbiome–immune–...

Inactivation of chromosomal genes through plasmid-encoded IS elements is an extended mechanism of antimicrobial resistance evolution in bacteria.

Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by l…

A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.

Author summary Viruses that infect bacteria, known as phages, are part of microbial communities and influence the abundance, diversity, and traits of their hosts. In an agriculture-related context, th...

Abstract. An unbiased and accurate estimation of intraspecies diversity, i.e., the extent of genetic diversity within species (or microdiversity), is cruci

Microbes get sick too - infected by bacteriophage or simply ‘phage’. A first post in a series on the hidden world of phage & how they transform human and environmental health.

An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...

Human host-associated cellular products may act as induction agents for bacteriophages.

It is not only antibiotics but also certain viruses – known as bacteriophages – that can kill off pathogenic bacteria. However, Switzerland lacks the legal framework for the use of these viruses in th...

A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development of next-generation antibiotics

The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

Nature Microbiology - A deep-learning algorithm unravels a collection of archaeasins, peptides from the archaeal proteome with potential antimicrobial activity and implications for the development...

Abstract. The importance of rarefying ecological or amplicon sequencing data to a standardized level of diversity coverage for reliable diversity compariso

Abstract. Long-term chronosequence studies have shown that, as glaciers retreat, newly exposed soils become colonized through primary succession. To determ