Scientists share help and advice on how they got their research discussions flowing.

The TRACS algorithm tracks bacteria, viruses and parasites in metagenomic or population sequencing data, detecting microbial transmission even when multiple strains coexist within a host.

Nature Microbiology, Published online: 01 May 2026; doi:10.1038/s41564-026-02333-3This Review summarizes recent advances in bacterial single-cell transcriptomics approaches, while also discussing technological and computational challenges remaining to be met and the need for standardization going forwards.

Recent studies have suggested that sugar substitutes might not be the free lunch they're advertised as. We asked experts what they thought.

The School has held the #1 spot since the rankings began in 1994. The School has also been named by peers as a leader in five specialty areas within public health this year.

Nature Reviews Gastroenterology & Hepatology, Published online: 09 April 2026; doi:10.1038/s41575-026-01205-9Diet–microbiome associations

On Tuesday, April 7 a leaked University video announced that Katalin Karikó will deliver the commencement speech for the Class of 2026. Karikó is a Hungarian-American biochemist and the 2023 winner of...

In the urogenital tract, dominant lactobacilli shape vaginal immunity and community stability. In this review, Dillen and Dricot et al. integrate clinical and mechanistic evidence on their molecular s...

Clostridium perfringens lacking perfringolysin O toxin isolated from preterm infants metabolizes human milk oligosaccharide disialyllacto-N-tetraose to produce metabolites that promote the growth of c...

Background The gut microbiome has been linked to mood disorders via communication along the gut-brain axis. We previously found levels of fecal Bacteroides were inversely associated with brain signatu...

Using individual-level data from the Swedish Prescribed Drug Register and fecal metagenomes of 14,979 individuals in Sweden, the authors examined the association between oral antibiotic use over 8 yea...

Immune systems in animals, plants, and bacteria often rely on intracellular nucleotide signaling, which viruses can block by sequestering or degrading these signals. We identified structural and bioph...

Seven firms reported inconsistent results on the same sample, some over multiple tests. These gut microbe discrepancies could have health consequences.

Prebiotic and probiotic interventions can induce therapeutically relevant shifts in the human microbiome, but their effects are variable across individuals. This study shows that metabolic models can ...

In a phase 2 trial evaluating healthy donor fecal microbial transplantation plus either anti-PD-1 in patients with non-small cell lung cancer or anti-PD-1 and anti-CTLA-4 in patients with melanoma, en...

Human genetic loci that associate with composition of the oral microbiome are identified using saliva-derived DNA, where the same host genetics also shapes oral health and genetic varia...

New recommendations advise limiting foods and drinks with nonsugar sweeteners, but industry groups maintain the products are safe.

The human gut microbiome is a complex community of bacteria, archaea, fungi, protozoa, and viruses that reside within the gastrointestinal (GI) tract (1). Notably, much of the literature regarding the...

Author summary Microbial communities, such as those living in the gut, play important roles in host health, yet we still do not fully understand how their diversity is established. In many cases, thes...

Leave-one-out cross-validation, a common machine learning evaluation method, has a pernicious flaw; a practical fix is presented.

The gut’s microbial ecosystem produces diverse metabolites that actively shape neural, immune, and endocrine function. Join leading researchers on December 12 as they share new discoveries into these ...

Prion-like proteins in Escherichia coli trigger an abortive infection mechanism in response to phage infection—a process similar to amyloid-mediated immune signalling in fungi and animals.