Farhangmehr et al. investigate functions of highly conserved intronic sequences in cell fitness using a CRISPR-based deletion screen. Deletions in FNBP4 intron lead to changes in p53 pathway genes. De...

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Abstract. For more than a century, scientists have worked to characterize, understand, and predict the consequences of mutations. For almost as long, scien

The images captured on May 29, 2026, by the Sentinel-3 satellite of the European Space Agency (ESA) clearly show the extent of the heat wave affecting Europe. T

In this Comment, Cedric Feschotte highlights evidence from diverse lineages showing that transposable elements are key drivers of evolutionary innovation, repeatedly introducing regulatory and coding ...

Last updated May 14, 2025

Structurally complex loci can repeatedly generate similar traits; Karageorgiou et al. established primate amylase locus as a structural variation hotspot, potentially seeded by transposable elements. ...

Small changes in the non-coding part of the genome have a key role in sex determination.

Abstract. Time-calibrating a phylogenetic tree is a fundamental step in phylogenetic inference, as it allows the study of macroevolutionary processes such

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As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...