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epithelial mechanics fan club @epimechfc.bsky.social · 26/07/2026

How do tissues safely remove cells? Join me, @marija-matejcic.bsky.social in this perspective on the past, present and future of epithelial cell extrusion 🧵 0/16

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Özge Özgüç @oozguc.bsky.social · 26/06/2026

happy #FluorescenceFriday from the bottom of my (stem cell colony) heart 🫀✨

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Daniel MK Lee @dannimklee.bsky.social · 24/04/2026

New Preprint alert!🚨 Super excited to share my postdoc work now on BioRxiv. How does PRC2 loss lead to developmental failures? We combined rapid protein degradation with TLS embryoid models to uncover temporal and lineage-specific dependencies 🧬. Preprint: doi.org/10.64898/2026.04.18.719361

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Xavier Trepat @xaviertrepat.bsky.social · 17/04/2026

Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.

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Özge Özgüç @oozguc.bsky.social · 31/03/2026

An egg-cellent use of micropatterning 🙌

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Carlos Pérez-González @cperez-gonzalez.bsky.social · 24/02/2026

Interested in doing a PhD in tumor mechanobiology? At Université Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab. If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!

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Quanta Magazine @quantamagazine.org · 27/02/2026

Sometimes, the only way to build back up is to let everything fall apart. This is certainly true at the cellular level. www.quantamagazine.org/break-it-to-...

quantamagazine.org

Break It To Make It: How Fracturing Sculpts Tissues and Organs | Quanta Magazine

Growing tissues can crack, break, and dissociate to form structures that can later withstand immense forces.

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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 17/02/2026

We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply! #optogenetics #metabolism #devbio #hESCs Please RT. Thank you!🙏

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allen institute @alleninstitute.org · 18/12/2025

How convenient - this tree already comes with ornaments! Get into the holiday spirit with this beautiful cell tree by @oozguc.bsky.social from @ibecbarcelona.eu. This beautiful fusion of science and art was made using our Lamin B1 stem cell line - complete with pink nuclei ornaments!

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Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 16/12/2025

I am putting together a collection of video-protocols we (will) use in tissue mechanics research🌀 I hope to help consolidate established methods, but also showcase a few up-and-coming ones in our blooming field. Abstract submission by March 2026! Get in touch✨ #JoVETissueMech #ReproducibleTissueMech

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Özge Özgüç @oozguc.bsky.social · 16/12/2025

For this festive season, I’m sending friends and family something a little different: postcards straight from the microscope. 🔬 Featuring my hiPSC Christmas tree from last year and a hiPSC colony turned into a festive bauble, with wishes for a season that’s festive at every scale. 🎄

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Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 15/12/2025

You know that sinking feeling 🥶 when it was all going well, but this past month your cells stopped attaching to their protein patterns? Could it be the change of season...? 🫠 Don't know what I mean and it all works? Help a friend! Get your protocol on video🎄🎁 #JoVETissueMech #ReproducibleTissueMech

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FocalPlane @focalplane.bsky.social · 05/12/2025

Meet the Epithelial Mechanics Fan Club @epimechfc.bsky.social Nimesh Chahare @onenimesa.bsky.social and Julia Eckert @juliaeckert.bsky.social introduce us to the Epithelial Mechanics Fan Club. Learn how you can get involved with this community: focalplane.biologists.com/2025/12/04/e...

focalplane.biologists.com

Epithelial Mechanics Fan Club - FocalPlane

Epithelial Mechanics Fan Club - News

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Manuel Thery @manuelthery.bsky.social · 05/12/2025

#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

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The Company of Biologists @biologists.bsky.social · 20/11/2025

Thank you to organisers Alex Dunn, @zevgartner.bsky.social, @adrianjacobo.bsky.social and Matthew Kutys and everyone who joined us for our Workshop on New Technologies for Studying and Reprogramming Development. #BiologistsWorkshops biologists.com/workshops

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allen institute @alleninstitute.org · 31/10/2025

A gourd-geous image of our lamin B1 cell line for your Halloween cell-ebrations! 🎃🧬 📸 Thanks to @oozguc.bsky.social for sharing this unbe-leaf-able shot! #FluorescenceFriday

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Xavier Trepat @xaviertrepat.bsky.social · 22/10/2025

📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now! events.ibecbarcelona.eu/embl-ibec-co...

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Carlos Pérez-González @cperez-gonzalez.bsky.social · 16/10/2025

1/ 🎉Excited to share our new preprint @vignjeviclab.bsky.social @davidbrueckner.bsky.social : "Self-organization of tumor heterogeneity and plasticity" biorxiv.org/content/10.1... Tumor heterogeneity and plasticity drive metastasis and relapse. How is tumor patterning coordinated? A thread👇

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Tom Golde @tomgolde.bsky.social · 02/09/2025

Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!

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RedPen/BlackPen @redpenblackpen.bsky.social · 08/08/2025

Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more

Cartoon of a scientist peering through a microscope saying "Whoaah!!!". Title says "The best part of Science is knowing, for a moment, something that nobody else in the world knows."

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Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 04/07/2025

On cell extrusion in the #intestine! After 80 years of observations, we finally took a deeper look thanks to 2D #organoids. We report: 3D #forces, #extrusion still only in the villus even without curvature, #lamellipodia generate 3D force.. and more. Have a look! www.biorxiv.org/content/10.1...

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Nimesh Chahare @onenimesa.bsky.social · 03/07/2025

Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025... 🧵 with pressure control, multiscale buckling, controlled wrinkling

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Xavier Trepat @xaviertrepat.bsky.social · 03/07/2025

🚨 Second preprint of the week! We uncover the multiscale dynamics of active viscoelastic buckling in epithelia. We harness these mechanical instabilities for synthetic morphogenesis. Led by @onenimesa.bsky.social 🙌. Theory by Marino Arroyo etal. @ibecbarcelona.eu www.biorxiv.org/content/10.1...

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Pau Guillamat @pauguillamat.bsky.social · 30/06/2025

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering

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the Node @the-node.bsky.social · 07/05/2025

Featured image with Özge Özgüç: the Node–FocalPlane image competition Find out more about @oozguc.bsky.social and the story behind "Cell-estial bloom", which won the image competition we organised with @focalplane.bsky.social: thenode.biologists.com/featured-ima...

A ‘Cell-estial Bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.

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Özge Özgüç @oozguc.bsky.social · 23/04/2025

From Turkiye’s Children’s Day to San Jordi in Catalonia, today is all about love, knowledge, and the future. @ibecbarcelona.eu turned my microscopy image into a bookmark for the occasion🎈 23 Nisan kutlu olsun & Feliç Diada de Sant Jordi!

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epithelial mechanics fan club @epimechfc.bsky.social · 05/04/2025

How do hydraulic forces impact critical processes such as tissue integrity, cell fate decisions, and embryo development? Hydraulics studies how fluids move and exert forces. Join me in exploring few articles on hydraulics in #EpithelialMechanics

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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 01/04/2025

We’re looking for PhD students to join the lab! 🧫🧑‍🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/ ‼️Deadline: April 15‼️

training.vbc.ac.at

PhD Program

Empowering Curious Researchers at the Vienna BioCenter PhD Program Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...

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Journal of Cell Science @jcellsci.bsky.social · 28/03/2025

In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro. journals.biologists.com/jcs/article/...

Cartoon of techniques to apply one-dimensional, in-plane or volumetric cell compression in vitro.

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the Node @the-node.bsky.social · 27/03/2025

🎉Congratulations to the Top 3 images from the Node–FocalPlane image competition! 1️⃣"Cell-estial bloom" by @oozguc.bsky.social 2️⃣"Dancing actinotroch" by @allancarbal.bsky.social 3️⃣"Who’s active?" by @jupeloggia.bsky.social thenode.biologists.com/results-from... @focalplane.bsky.social #biologists100

"Cell-estial bloom" Image from Özge Özgüç:
A ‘Cell-estial bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.

"Dancing actinotroch" by Allan Carrillo-Baltodano:
Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification.

"Who’s active?" by Julia Peloggia de Castro:
The image depicts a zebrafish embryo at 9 hours post-fertilisation on a lateral view. Cells are stained with MitoTracker, which labels active mitochondria, and cell membranes are labelled in cyan with a EGFP transgenic membrane tag. Image was taken using a 20x objective on a spinning disk confocal microscope.

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FocalPlane @focalplane.bsky.social · 27/03/2025

The Node-FocalPlane image competition at #biologists100. All the votes are now in, and we can announce our three prize winners: @oozguc.bsky.social, @allancarbal.bsky.social and @jupeloggia.bsky.social. Read more ⤵️: focalplane.biologists.com/2025/03/27/a...

focalplane.biologists.com

Announcing the winners of the Node–FocalPlane image competition. - FocalPlane

Announcing the winners of the Node–FocalPlane image competition. - News

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Özge Özgüç @oozguc.bsky.social · 27/03/2025

Whaaat?! Cell-estial Bloom took 1st place in the Node–FocalPlane image competition! 🤯🤯🤯

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Özge Özgüç @oozguc.bsky.social · 27/03/2025

On my way to to the International Dutch Embryo Model Meeting 2025! 🚆 Excited to dive into the latest advances and have some great discussions. If you’re around and curious about mechanics in development / mechanically accessible models, come find my poster!! #IDEMM25

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Özge Özgüç @oozguc.bsky.social · 25/03/2025

My image on display at #Biologists100! 🖼️🔬 So surreal to see “Cell-estial Bloom” showcased in this gallery among so many stunning images! Huge thanks to @LFort8 for the photo! Also: ✨ it is the last day to vote! ✨ thenode.biologists.com/vote-for-you... @the-node.bsky.social @focalplane.bsky.social

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Kristina Stapornwongkul @kstapornwongkul.bsky.social · 20/03/2025

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980

imba.onlyfy.jobs

Research Technician

IMBA - Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at t...

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the Node @the-node.bsky.social · 11/03/2025

Together with @focalplane.bsky.social, we're having an image competition to accompany the #Biologists100 conference. Thank you everyone who submitted their images. Shortlisting only 15 was tough! Browse through the gallery and vote for your favourite image: thenode.biologists.com/vote-for-you...

thenode.biologists.com

Vote for your favourite image in the Node–FocalPlane image competition - the Node

Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.

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Özge Özgüç @oozguc.bsky.social · 12/03/2025

My image is shortlisted and will be displayed at #100Biologists! 🎉 This “Cell-estial Bloom” features LaminB-labeled cells from @alleninstitute.bsky.social glowing in all their fluorescent glory! ✨ All very incredible images—check them out and vote for your favorite (Hope it’s mine! 🤞)!

a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.

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John Wallingford @jbwallingford.bsky.social · 11/03/2025

A woman studies embryos for decades, struggles for funding and respect. She publishes under her husband’s name, until they divorce. A single mother, she moves across an ocean to continue her studies. It all sounds quite modern, until you learn that she also worried she’d be burned as a witch. 🧵 1/15

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FocalPlane @focalplane.bsky.social · 11/03/2025

Voting is open in our image competition with @the-node.bsky.social. Thanks to everyone that entered, and congratulations to our final 15. Now it's your turn to pick your favourite! Look out for our gallery of images at the Biologists @ 100 conference #biologists100.

focalplane.biologists.com

Vote for your favourite image - FocalPlane

Vote for your favourite image - News

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epithelial mechanics fan club @epimechfc.bsky.social · 16/02/2025

Tissues are dynamic and investigating cellular mechanical states can be crucial for understanding biological processes. But how to do it? We are @andreasschoenit.bsky.social and @luanger.bsky.social from @bladoux.bsky.social / @rmmege.bsky.social lab highlighting ways to assess tissue stresses.

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Özge Özgüç @oozguc.bsky.social · 14/02/2025

Now that you said it… it gives eye of sauron vibes too😅

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Özge Özgüç @oozguc.bsky.social · 14/02/2025

It is #FluorescenceFriday! Perfectly suited for Valentine’s Day—a 2-cell stage mouse embryo where actin staining created a heart-shaped negative space around its nucleus🔬. Captured it 4 years ago, but still one of my favorites for this time of year ❣️

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Alice Perucca @aliperri.bsky.social · 10/02/2025

3/7: Why MIRO is unique? ✅ Immunocompetent: tracks #ImmuneCells movement & interactions ✅ Cells self-organize & build their own extra-cellular matrix ✅ Cost-effective, reproducible & user-friendly 🎥 cellular organization in MIRO #ECM #TumorEcosystem

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Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 11/02/2025

We have a new #stopdoing #science meme, courtesy of Miquel Bosch Padros from the @xaviertrepat.bsky.social lab. Late for #mechanobiology Monday, but here to stay on your lab meme boards forever.

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Özge Özgüç @oozguc.bsky.social · 31/12/2024

No need for explosives, this year's firework show is cell-powered! 🔬💥 Check out the "fireworks" created by cells pulling on the substrate and displacing tiny beads, visualized with #3DTFM ! 🎇 Let’s make 2025 explosive with science! 👩‍🔬🎉 #HappyNewYear

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