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Neha Ghosh

@nehaghosh.bsky.social
896 followers 643 following 175 posts

K99|R00 NEI, NIH Postdoctoral Fellow Treisman Lab NYU School of Medicine Tissue patterning| Organ morphogenesis

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Reposted by Neha Ghosh
Development @dev-journal.bsky.social · 04/09/2026
Apical extracellular matrix development Read this Spotlight from our special issue #DevSIextracellular by Maxwell Heiman @heiman.bsky.social and Meera Sundaram @meera-sundaram.bsky.social. doi.org/10.1242/dev....
Composite figure showing the diversity of apical extracellular matrices (aECM) across animals. Arthropod examples include a butterfly wing and electron micrographs of butterfly scales, crab cuticle, and layered spider cuticle. Drosophila examples show sensory structures, olfactory nanopores, tracheal cuticle, and larval denticles. Vertebrate examples include crocodile scales, a bird feather, hamster zona pellucida fibrils, and cracked elephant skin, illustrating wide variation in aECM structure and function.
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Reposted by Neha Ghosh
Genetics Society of America @genetics-gsa.bsky.social · 20/08/2026
What keeps scientists coming back to the Annual Drosophila Research Conference year after year? From new collaborations to lasting friendships, mentorship and career-changing opportunities, Dros is more than a meeting—it’s a community. 🔗 Read the blog: buff.ly/AX6jwI4
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 18/06/2026
The array of organs in the animal body differ dramatically in their architecture, but cell-cell adhesion mediated by cadherins is a common principle. Our lab usually focuses on epithelia but cadherins are also active in migrating mesenchymal cells like these migrating testis myoblasts 1/n 🧪
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Neha Ghosh @nehaghosh.bsky.social · 17/06/2026
Many congratulations, Priya! 🎉
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Reposted by Neha Ghosh
Elena Vasileva @evasileva.bsky.social · 19/05/2026
Our lab website is live! 🚀🐟 www.vasilevalab.com We use genetic #zebrafish models and molecular oncology approaches to study pediatric cancer and discover new therapeutic strategies. We’re growing and recruiting postdocs and research technicians! #PediatricCancer #Zebrafish #PostdocJobs
vasilevalab.com
Home | Vasileva Lab
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Neha Ghosh @nehaghosh.bsky.social · 20/05/2026
Huge congratulations, Elena! 🎉 Best wishes for the journey ahead
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Reposted by Neha Ghosh
BWJones @bwjones.bsky.social · 30/03/2026
New publication: Inner-Retinal Changes In AMD: Evidence, Mechanisms, and Future Perspectives. A fun project with Matt Trinh, Michael Kalloniatis, myself, Glenn Yiu, Enrico Borrelli, and Lisa Nivison-Smith bryanwjones.com/2026/03/inne...
Normal neuro-vascular maps of the macular inner-retina.
Top half clinical imaging: Topographic analyses from 96 normal eyes for OCT thickness (Trinh et al., 2022b) and 57 normal eyes for OCTA signal (Trinh et al., 2021a), with exclusion of any retinal macular/optic nerve pathology. Common locations of the optic nerve head and retinal blood vessels were excluded from OCT scans (Burke et al., 2024a, 2024b; Tong et al., 2020; Trinh et al., 2020, 2021b, 2022b). OCT layers are depicted on the left using a standardised thickness scale (darker green = greater thickness), while OCTA slabs are depicted on the right using a standardised OCTA signal (darker red = greater OCTA signal). Vascular slab approximations were adapted from Campbell et al. (Campbell et al., 2017). For reference, the RPE-BM (drusen layer) is shown using OCT thickness, and the choriocapillaris is shown using OCTA signal.
Bottom half histological imaging: Resin embedded, 100 nm serial section of mid-peripheral retina of aged, normal human eye (87 year old male) with amino acid immunolabelling of GABA, glycine, and glutamate mapped to the red, green, and blue colour channels, respectively, and rod opsin labelling indicated in yellow. The section illustrates the laminar organisation of the inner- and outer-retina for cross-reference with the OCT layers above and the distinct neurochemical signatures of neurons in these layers. White scale bar 100 μm.
RNFL, retinal nerve fibre layer; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; IS/OS, photoreceptor inner- and outer-segments; RPE-BM, retinal pigment epithelium to Bruch's membrane.
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Daniel Ríos @yosoyden.bsky.social · 01/04/2026
Yay! Our paper is now out @emboreports.org! I posted about it a while back (tinyurl.com/yc7td3px) but the work really improved thanks to the wonderful feedback from three anonymous reviewers 🙏 (1/4)
link.springer.com
Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila - EMBO Reports
Organ functionality requires the precise coordination of diverse tissues during development. Halfway through Drosophila embryogenesis, two lateral epidermal sheets stretch to fuse at the dorsal midlin...
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Parichy Lab | Dave Parichy @dparichy.bsky.social · 03/04/2026
Zebrafish finds Nemo. New paper with our great collaborators on gap junctional communication in widely divergent species. www.nature.com/articles/s41...
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John Tuthill @tuthill.bsky.social · 24/03/2026
🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...
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MwahahahahahadScientist @mads100tist.bsky.social · 24/03/2026
Are you a postdoc in the job market? Do you have a cool story in the making? You forgot to have lunch and just run your gel backwards? You can't sleep because of the prospect of applying to 100 places and getting two replies only? Apply! 🧪🐟https://www.germanfishmeeting.org/from-postoc-to-pi
germanfishmeeting.org
From Postoc to PI Session | German Fish Meeting
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Adam Blake @ajblake05.bsky.social · 10/07/2025
Our new paper is now out in @jexpbiol.bsky.social!!! We had all sorts of fun generating LED stimuli for mosquitos to investigate their visual preferences in the presence of different odors. The paper is open access and available here: journals.biologists.com/jeb/article/...
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Stefan Harmansa @morphomechanics.bsky.social · 23/03/2026
Excited to share our new article, ‘Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing’, now online in Current Biology. doi.org/10.1016/j.cu... There’s also a great accompanying Dispatch: doi.org/10.1016/j.cu... #MatrixMechanics #DevBio
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Neha Ghosh @nehaghosh.bsky.social · 24/03/2026
💃💃💃
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Neha Ghosh @nehaghosh.bsky.social · 24/03/2026
Thank you 😊
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Neha Ghosh @nehaghosh.bsky.social · 24/03/2026
Thank you so much, Stefan!
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Neha Ghosh @nehaghosh.bsky.social · 24/03/2026
Thanks for the warm words, Shefali! 🎉
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PLOS Biology @plosbiology.org · 23/03/2026
How does the #corneal #lens in the #fly eye get its light-focusing shape? @nehaghosh.bsky.social &co show that central cells produce large amounts of #chitin to form the thick central corneal lens; peripheral cells produce smaller amounts to form tapered lens edges @plosbiology.org 🧪 plos.io/4lLNgeY
Chitin organization during corneal lens morphogenesis. Top row: apical surfaces of wild-type (white1118) mid-pupal retinas stained for chitin with chitin-binding domain probe CBD (green) and E-Cadherin and N-Cadherin (magenta). From left to right, the times are 48 h after puparium formation (APF), 50 h APF, 51 h APF, 52 h APF, and 54 h APF. Middle row shows enlargements of single ommatidia. Bottom: Diagram of chitin (green) organization during corneal lens development. CC, cone cells; 1º, primary pigment cells; 2º, secondary pigment cells; 3º, tertiary pigment cells; B, mechanosensory bristles.
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epithelial mechanics fan club @epimechfc.bsky.social · 22/03/2026
Hello epithelia enthusiasts! I’m @inesfournon.bsky.social and I study epithelial mechanics in sea anemones 🪼 Did you know epithelial cell extrusion had never been described outside bilaterian animals before? Well… not anymore 👀 Read ⬇️🧵1/9
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Neha Ghosh @nehaghosh.bsky.social · 21/03/2026
Huge congratulations 🎉
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EMBO Reports @emboreports.org · 21/03/2026
Geraldine Seydoux @hhmi-science.bsky.social @jhu.edu and co-workers show that germ granule component PGL-3 undergoes #RNA independent #phaseseparation driven by structured domains that oligomerize and interact with RGG motifs. -> link.springer.com/article/10.1...
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Neha Ghosh @nehaghosh.bsky.social · 21/03/2026
Yaaassssss 💃 💃 💃
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Neha Ghosh @nehaghosh.bsky.social · 21/03/2026
I am excited to share my new paper in @plosbiology.org . Here we show the role of chitin, a polysaccharide, in controlling the shape of the fly corneal lens. journals.plos.org/plosbiology/...
journals.plos.org
Curvature of the Drosophila corneal lens depends on localized chitin secretion
How does the corneal lens in the fly eye acquire its light-focusing shape? This study shows that centrally located cells produce large amounts of chitin to form the thick central corneal lens, while p...
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Kara McKinley @karalmckinley.bsky.social · 12/03/2026
1st McKinley Lab grad student’s 1st preprint! @claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy. Come for her GORGEOUS images, stay for her incredible discoveries. www.biorxiv.org/content/10.6... w/ @akelleher1017.bsky.social
Immunofluorescence image of a mouse uterus with epithelium labeled in cyan. There is a folded lumen in the center and glands branching off like bunches of grapes.
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Neha Ghosh @nehaghosh.bsky.social · 12/03/2026
Gorgeous! Looks like a bouquet of flowers…
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Jens Rister @rister.bsky.social · 15/01/2026
Can't wait to serve again as co-director of the CSHL Drosophila Neurobiology course this year! 🧪🪰👀 Application Deadline: March 27 meetings.cshl.edu/courses.aspx... @cshlnews.bsky.social @cshlcourses.bsky.social
meetings.cshl.edu
Drosophila Neurobiology: Genes, Circuits & Behavior
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
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Reposted by Neha Ghosh
Alex Schier @schierlab.bsky.social · 12/03/2026
Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
science.org
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
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Alex Eve @amjeve.uk · 11/03/2026
Enhancers are genetic regions that promote the activation of neighbouring genes. @radaiglesiaslab.bsky.social asks how long-range enhancers maintain specificity by constructing synthetic gene landscapes and exploring how they affect gene activity. #gfe2026 Alvaro's @dev-journal.bsky.social Review⤵
doi.org
Enhancer-gene specificity in development and disease
Summary: This Review discusses recent insights into the factors controlling enhancer specificity and how this might help us understand the genetic basis of human disease.
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Ben Hopkins @brhopkins92.bsky.social · 06/03/2026
Quick plug for our new resource, the Drosophila Species Stock Exchange. This is a database and mailing list that documents species currently in culture and the labs holding them. If you want to know more or sign up then please get in touch. See attached for more info and please share!
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Shefali @iamshef.bsky.social · 09/03/2026
Excited to be presenting my work at #ASBMB26 on how glucose metabolism interacts with mTor signaling in #Drosophila in the Integrated Metabolism session on March 9 at 2.50 pm in the Cherry Blossom room. It's my first time attending #ASBMB and we are having a wonderful time here in DC ☺️
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 06/03/2026
If you're at #Dros26 and are interested in how cells change shape & move during morphogenesis & how different classic cadherins influence different cell behaviors, check out the talk by @saraheclark.bsky.social in Cell Biology: Cytoskeleton, Organelles, & Trafficking II Sat 9:15 🧪
Picture of SarahTalk slide title with images of testis defects
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Neha Ghosh @nehaghosh.bsky.social · 07/03/2026
Me too 😭
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SeYeon Chung @seyeonchung.bsky.social · 06/03/2026
Excited to share our work at #DROS26! I’ll be giving a talk today at 11 AM in the Patterning, Morphogenesis, and Organogenesis session. Also come check out posters from our lab: Elizabeth (F 2-4 pm), Debbie (S 1:30-3:30 pm)
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Neha Ghosh @nehaghosh.bsky.social · 06/03/2026
Best wishes for your talk, Shefali!
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Neha Ghosh @nehaghosh.bsky.social · 06/03/2026
Many congratulations to you! 🎉
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Felipe Opazo @opazo.bsky.social · 04/03/2026
New preprint out! In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...
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Alex Gould Lab @alexgouldlab.bsky.social · 25/02/2026
#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social @dev-journal.bsky.social tinyurl.com/4jpw9jd6
ShineGAL4 FLP-out clones
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Leah Greenspan @ljgreenspan.bsky.social · 24/02/2026
Excited to have started my new lab in Human Genetics at Pitt Public Health! We study wound healing in diabetes & aging using adult zebrafish. Check out this movie showing neutrophil dynamics after injury. Now recruiting research staff, grad students, and postdocs. DM me if interested.
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Neha Ghosh @nehaghosh.bsky.social · 26/02/2026
Many congratulations, Leah! Best wishes for the exciting times ahead 🎉
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Rodrigo Fernandez-Gonzalez @rodrigofg.bsky.social · 20/02/2026
And if you wanted proof ... @dev-journal.bsky.social
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Jason Rasgon @vectorgen.bsky.social · 20/02/2026
I love GFP
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PLOS Biology @plosbiology.org · 20/02/2026
#Photoreceptor cells vary in the morphology of the light-absorbing outer segment, but why? This study in #zebrafish shows that the wavelength sensitivity of the expressed #opsin and the intensity of light exposure determine outer segment morphology @plosbiology.org 🧪 plos.io/4aKJi15
Left: This image visualizes the precise retinal mosaic formed by ultraviolet-sensitive cone (red) cells in zebrafish, highlighting the organized cellular landscape that underlies this research. Right: This image highlights the abundant cone population in the adult zebrafish retina, with UV-sensitive cones distributed throughout the tissue. The visualization, achieved using the Tg(sws1:GFP) transgene to label UV cone cell bodies. Creator: Jingjin Xu.
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Yarui Diao @yaruidiao.bsky.social · 20/02/2026
Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.
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PLOS Biology @plosbiology.org · 20/02/2026
The #fly community aims to achieve a comprehensive genomic study of the Drosophilidae family. @pankajd.bsky.social @bernardkim.bsky.social @petrovadmitri.bsky.social @darrenobbard.bsky.social present a comparative gene annotation for 301 #Drosophilidae species @plosbiology.org 🧪 plos.io/4c3pyrI
Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.
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Stefan Luschnig @luschnig.bsky.social · 18/02/2026
New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila See tinyurl.com/yhbwd9xh @sfb1348.bsky.social
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Sarah Cohen @cohenlaboratory.bsky.social · 16/02/2026
Cells come in many shapes and sizes, with diverse physiological functions. But how do #organelles and their interaction networks remodel during #differentiation of stem cells into different cell types? Here’s what we discovered about neuronal differentiation: 1/13
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Alejandro Torres-Sánchez @torres-sanchez.bsky.social · 12/02/2026
Development builds... But it also breaks! Planarians split to reproduce. Hydra tears open a mouth. Embryos fracture to make cavities. Failure? No. Fracture is essential to development. Our new review on fracture physics and its uses in development: journals.biologists.com/dev/article/...
journals.biologists.com
Break to build: fracture as a unifying morphogenetic strategy
Summary: This Review presents mechanical fracture as a unifying morphogenetic strategy and describes how developmental systems actively exploit mechanical fracture to drive morphogenesis, reproduction...
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Wyoming Wormboy @wyomingwormboy.bsky.social · 14/02/2026
Our uncorrected spoof, I mean proof! More forays into lipids and sensors and the intricacies of membrane trafficking. Thanks again to three reviewers for authentically helping us make this a better manuscript. Peer review is essential. dx.plos.org/10.1371/jour...
dx.plos.org
PIKI-1, a class II PI 3-kinase, functions in endocytic trafficking
Author summary The uptake of materials from outside the cell and their subsequent delivery to specific intracellular locations are essential for cell function and survival. Two of the mechanisms that ...
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Katja Röper @katjaroeper.bsky.social · 11/02/2026
Our take on a really interesting new study by the Franz lab at UCL, a version of epithelial polarity where you would not expect it! Read our Spotlight and the original paper!
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Sara Wickstrom @sarawickstrom.bsky.social · 10/02/2026
Excited to share our work on epithelial multilayering - identifying why stem cell stay in the basal layer and how and why differentiating cells move up. Great collab with @manningresearch.bsky.social and Niessen labs! Check out preprint and great summary below www.biorxiv.org/content/10.6...
biorxiv.org
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