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Plants perceive pathogenic threats through receptors localized at the plasma membrane and inside cells to initiate pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), respectively....

Cyclic oligonucleotide–based antiphage signaling systems (CBASS) are bacterial immune pathways evolutionarily related to cGAS-STING (cyclic GMP-AMP synthase–stimulator of interferon genes) in humans. ...

Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.

The conservation of immune systems from prokaryotes to eukaryotes can guide discovery of immunity genes across the tree of life. Most studies to date have focused on metazoan systems, while the extent...

Sophien Kamoun to give the opening keynote talk:                AI-Guided Studies of Plant Immunity Save the Date Sunday, 18 July – Thursday, 22 July Jeju, South Korea The 22nd International Congress ...

YouTube video by IS-MPMI

Abstract. Membraneless organelles (MLOs) in eukaryotic cells, such as the nuclear Cajal body (CB), have been notoriously difficult to biochemically isolate

Bentham Lab, Centre for Programmable Biological Matter, Durham University. Structural biology and de novo protein design applied to host-pathogen interactions, plant immunity, and neglected tropical d...

Congratulations to the nine researchers from Brazil (4), Colombia (4), and Mexico (1), who have just been awarded an ERC Starting Grant.

Nominations for the 2027 Awards are Open! IS-MPMI’s 2027 awards recognized the outstanding service, scientific innovations, and significant accomplishments of our members​ with the Early Career Achiev...

Proposed model for the stepwise evolution of DELLA functions in the green lineage.

The gradual assembly and oligomerization of cell surface receptors are critical for regulating immune activation and turnover. Yet, how dynamic, spatiotemporally regulated assembly enables rapid and s...

Genetically encoded biosensors are central to plant cell biology, but low reporter signal can limit their use. Here, we developed modular intronised fluorophores to improve reporter output in transien...

Molecular phylogenetics guide for the assembly of gene trees. A guide to identifying homologous genes and constructing trees with command line tools. Intended as a practical guide and a teaching re...

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The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback lo...

To cause rice blast disease, the filamentous fungus Magnaporthe oryzae develops a specialised infection cell called an appressorium, which generates enormous turgor to breach the rice leaf cuticle. Al...

The specification of embryonic stem cells capable of self-renewing and differentiation into virtually any cell type, is one of the most consequential events in the development of a multicellular organ...

Plants use mobile small RNAs to coordinate development and stress responses. Here, we review recent advances revealing mechanisms shaping the mobile sRNA p

Lichens are stable multipartite symbioses in which a fungal mycobiont associates with one or more photosynthetic partners while hosting complex microbiomes. Secreted antimicrobial proteins (AMPs) have...

Recent discoveries on bacterial immunity have revealed that several protein domains involved in anti-phage defense are conserved in eukaryotes, such as SIRim, TIR, PNP and gasdermin. Bacterial immune ...

Computational Biologist (m/f/d) - Genome Editing Trait Discovery