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Giuliana Hessler

@giurassicpark.bsky.social
743 followers 180 following 6 posts

Postdoctoral researcher at Uni Zurich in Cyril Zipfel’s group. PhD graduate of Jane Parker‘s lab at MPIPZ Cologne. Studying signaling mechanisms in plant immunity 🌱 she/her

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Reposted by Giuliana Hessler
Fantin Mesny @mesny.bsky.social · 01/10/2026
5 years ago, @hacquardst.bsky.social and I became very interested in 𝑃𝑙𝑒𝑐𝑡𝑜𝑠𝑝ℎ𝑎𝑒𝑟𝑒𝑙𝑙𝑎 𝑐𝑢𝑐𝑢𝑚𝑒𝑟𝑖𝑛𝑎, an emerging fungal pathogen that colonizes the roots of many plants 🌱 🍅 🌾 🆕📝 Final result of a huge team effort to uncover the bases of its multi-host compatibility👇 www.nature.com/articles/s41...
nature.com
Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts - Nature Microbiology
Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.
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parkergroup.bsky.social @parkergroup.bsky.social · 08/09/2026
Parker Lab out and about this week 🌱 @junli-wang.bsky.social is presenting her work at #ECPP26, while @federicalocci.bsky.social will be giving a talk at #PPath26 on Thursday at 12:15. Great to see familiar faces from the lab and catch up with friends and collaborators!
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Mariana Schuster @marischuster.bsky.social · 07/09/2026
I'm excited to share that my newly funded #ERCStG FRONTERA is recruiting two postdoctoral researchers at @ipbhalle.bsky.social 🌱🔬 If you are passionate about plant immunity, proteolysis, membrane proteins, or proteomics, I'd love to hear from you. 🧵 Please RT/share!
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Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 05/08/2026
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs
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Reposted by Giuliana Hessler
Álvaro Fernández @alvaroferfer.bsky.social · 25/06/2026
With a bit of delay, but my latest work on engineering a sensor for plant proteolysis was published online in The Plant Cell (1/5).
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Reposted by Giuliana Hessler
parkergroup.bsky.social @parkergroup.bsky.social · 09/06/2026
TIRs are key regulators of plant immunity, but the role of conserved TIR-only proteins has remained unclear. Here, we compare TIR-only proteins from Arabidopsis and barley and show that they share a conserved role in plant immunity. www.biorxiv.org/content/10.6...
biorxiv.org
Conserved TIR-only proteins drive transcriptional defense and basal immunity in dicot and monocot plants
Toll/interleukin-1/resistance (TIR) domain NADase enzymes signal in plant immunity by producing ribosylated nucleotide second messengers which activate EDS1 dimer-helper NLR pathways to restrict patho...
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Reposted by Giuliana Hessler
Diana Gómez De La Cruz @dianagdlc.bsky.social · 05/06/2026
So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇 www.science.org/doi/10.1126/...
science.org
Molecular mimicry of a pathogen virulence target by a plant immune receptor
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
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Reposted by Giuliana Hessler
Mauricio Contreras @mpcontreras.bsky.social · 04/06/2026
Molecular mimicry of a pathogen virulence target by a plant immune receptor | Science www.science.org/doi/10.1126/...
science.org
Molecular mimicry of a pathogen virulence target by a plant immune receptor
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
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Reposted by Giuliana Hessler
Jinyi Zhu @jinyi-zhu.bsky.social · 10/05/2026
Fungi deploy antimicrobial proteins (AMPs) to compete with microbes, including bacteria. But can bacteria fight back? We @teamthomma.bsky.social found that some AMP-sensitive bacteria can repress AMP deployment, suggesting an unrecognized bacterial–fungal arms race. www.biorxiv.org/content/10.6...
biorxiv.org
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Fantin Mesny @mesny.bsky.social · 29/04/2026
So, the ancestral antimicrobial function of 424Y proteins supports diverse fungal lifestyles through microbial antagonism. In plant pathogens, acquisition of an NLS enabled them to also manipulate host immunity. A clear example that immunomodulatory effectors evolved from ancient antimicrobials!
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Fantin Mesny @mesny.bsky.social · 29/04/2026
🎉 📰 Very happy to share the journal publication of our manuscript "Plant-associated fungi co-opt ancient antimicrobials for host manipulation"! #ScienceAdvancesResearch @science.org @teamthomma.bsky.social www.science.org/doi/10.1126/...
science.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Fungal effectors may have evolved from ancient antimicrobials, shaping plant microbiota and immunity during infection.
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Reposted by Giuliana Hessler
Thomas Ott @ottlab.bsky.social · 13/04/2026
New pre-print from the lab! We show that the subtilase SBT12a is essential for symbiosome stabilization in Medicago. Using HUNTER proteomics, we even got some of its substrates. Have a look. www.biorxiv.org/content/10.6...
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Giuliana Hessler @giurassicpark.bsky.social · 28/02/2026
It was a pleasure to host you, @marischuster.bsky.social. Thank you for all the inspiring scientific discussions and sharing your protease fascination with us.
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Reposted by Giuliana Hessler
Fantin Mesny @mesny.bsky.social · 15/08/2025
📣 NEW PREPRINT 📝 We identified evolutionary origins of many fungal effectors! We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression. www.biorxiv.org/content/10.1... cc @teamthomma.bsky.social
biorxiv.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
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Fantin Mesny @mesny.bsky.social · 20/07/2025
Coming back from 5 days of great science at #2025ISMPMI, I wanted to share some of my highlights, and particularly to mention my favourite presentations by early career researchers. A thread 🧵 ⬇️
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Reposted by Giuliana Hessler
Ksenia Krasileva @kseniakrasileva.bsky.social · 17/07/2025
«Nothing in plant-microbe interactions makes sense except in the light of microbe-microbe interactions » @teamthomma.bsky.social #2025ISMPMI
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parkergroup.bsky.social @parkergroup.bsky.social · 17/07/2025
Parker Group alumni, from the early 2000s to 2025, the best folks! Grateful for everyone who helped shape the science over the years #2025ISMPMI Thanks @federicalocci.bsky.social for taking the picture
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Gitta Coaker @gittacoaker.bsky.social · 17/07/2025
www.biorxiv.org/content/10.1... Up next at #2025ISMPMI @kseniakrasileva.bsky.social discussing work on protein language model for receptor engineering.
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margotraffeiner.bsky.social @margotraffeiner.bsky.social · 16/07/2025
Happy to meet you at poster no. P-405 and to talk about my project at #2025ISMPMI this afternoon! 🌿
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Giuliana Hessler @giurassicpark.bsky.social · 16/07/2025
#2025ISMPMI my poster is up! If you are interested in how a family of plant endogenous peptides can act as both signaling and antimicrobial peptides, pass by my poster P-222 on Thursday afternoon.
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Fantin Mesny @mesny.bsky.social · 16/07/2025
My poster is up at #2025ISMPMI. Come by P-372 Thursday afternoon if you are interested in fungal evolution, effectors and microbial competitions! More research by @teamthomma.bsky.social at P-091, P-170, P-299, P-317, P-337 and P-388.
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Reposted by Giuliana Hessler
Liz Florez @lizflorez.bsky.social · 14/07/2025
🧪⚔️ When a fungal effector tries to coexist with plant apoplastic bacteria My poster’s not up until Thursday, but you can already check it out on Zenodo 👀 📎 zenodo.org/records/1585... 🧾 Poster P-166, Thur 17th, 1:30 pm #2025ISMPMI
zenodo.org
The fungal effector AvrStb6 regulates the wheat pathobiome
Zymoseptoria tritici, the causal agent of the foliar disease Septoria tritici blotch (STB), is a major wheat pathogen in Europe. Although several wheat resistance (R) genes have been identified, Z. tr...
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Giuliana Hessler @giurassicpark.bsky.social · 14/07/2025
Great talk at #2025ISMPMI by @federicalocci.bsky.social on a TN protein in systemic resistance. So happy to catch up on @parkergroup.bsky.social projects!
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Mariana Schuster @marischuster.bsky.social · 14/07/2025
I am looking for a (bio)chemist to join the lab and help us making affinity-based probes for proteases! The project is truly interdisciplinary with a strong computational chemistry component, peptide synthesis and plant biochemistry! Text me if interested and please spread the word!
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Max Planck Institute for Plant Breeding Research @mpipz.bsky.social · 18/03/2025
We are happy to announce another PhD success at @mpipz.bsky.social! 🎉 Dr. Henriette Läßle has passed her viva in Jane Parkers’s lab. Huge congrats, Dr. Läßle, and best of luck with your next steps! 🚀🌱🎓 #PhDSuccess #PlantScience #PhDone
The post shows a picture of Henriette after successfully passing his viva on a green background with words congratulating him on acquiring the PhD title.
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Christine Faulkner @pdchristine.bsky.social · 11/03/2025
We're looking for a postdoc to join the lab to work on cell-to-cell communication via the apoplast. Candidate must be brave, as they will have to lead us (me) away from the plasmodesmata-lands we've inhabited for so long! www.jic.ac.uk/vacancies/po...
jic.ac.uk
Postdoctoral Researcher (Faulkner Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Faulkner Group at the John Innes Centre, working on cutting-edge science in the field of Cell & Developmental Biology.
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Jack Rhodes @jackrhodes.bsky.social · 16/12/2024
Are you interested in receptor kinase signalling and plant immunity? We have several positions open to join our team at @thesainsburylab.bsky.social in Norwich. #plantscience #mpmi #plantimmunity #sceincejobs Please get in touch if you have questions 1/5
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