iiinova — where your digital self keeps evolving

Reposted by Andy Posbe

Sophien Kamoun @kamounlab.bsky.social · 14/09/2026

We just published: Fold on Tight — 10 lessons on AI structure prediction Andy Posbe @adnroide.bsky.social turned our ten lessons on AI structure prediction into a thread. Here it is, one lesson at a time. kamounlab.medium.com/fold-on-tigh...

kamounlab.medium.com

Fold on Tight — 10 lessons on AI structure prediction

Andy Posbe turned our ten lessons on AI structure prediction into a thread. Here it is, one lesson at a time.

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Andy Posbe @adnroide.bsky.social · 11/09/2026

No one remembers authorising this firmware update

Five researchers hold freshly printed immune receptor structures while the office Ricoh continues production, despite nobody remembering authorising this feature.

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Reposted by Andy Posbe

Alex McClelland @alexjmcclelland.bsky.social · 11/09/2026

Very pleased to have contributed to this concise, digestible overview of AI structure prediction! I think this is a great resource for newbies and experienced AlphaFold users alike. Happy Folding!

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Andy Posbe @adnroide.bsky.social · 10/09/2026

Excited to share Fold on Tight! 🎉 We distil recent advances in plant immunity into 10 lessons for using AI structure prediction critically and effectively, in plants and beyond. 📝 zenodo.org/records/2210...

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Reposted by Andy Posbe

Jiorgos Kourelis @jiorgoskourelis.bsky.social · 23/01/2026

📢 2 PhD Positions Available in Plant Immune Receptor Bioengineering at Imperial College London 🌱 Start: Oct 2026 📅 Deadline: 10 Feb 2026 🇬🇧 UK/settled status only 💰 Fully funded (48 months) ℹ️ Info: shorturl.at/po61I #PlantImmunity #PlantPathology #SyntheticBiology 🙏 Share with interested candidates!

imperial.ac.uk

PhD Opportunities | Faculty of Natural Sciences | Imperial College London

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Clémence Marchal @clemmar.bsky.social · 03/12/2025

Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social www.biorxiv.org/content/10.6...

CC-NLRs exhibit diverse conformations in the resting state.
Figure depicts different NLR resting and activated states. While ZAR1 exists as a monomer bound to its guardees in its resting state, several forms have been observed for the NRC2 helper, including dimers, tetramers, and filaments. While filament-like structures were observed via confocal microscopy for NRC2 upon overexpression in planta, these structures were not detected for its paralog NRC4, suggesting a potentially different resting state configuration for NRC4. Our work suggests that the Pik CC-NLR pair forms a hetero-complex bound to the plasma membrane in its resting state. How effector binding to the integrated domain (ID) of the Pik-1 sensor leads to the activation of the complex remains to be determined.

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Reposted by Andy Posbe

Sainsbury Laboratory Cambridge University (SLCU) @slcuplants.bsky.social · 03/11/2025

🎃✨ Pumpkin perfection! We were seriously impressed by the beautifully carved and brilliantly lit pumpkins from @thesainsburylab.bsky.social🕯️ We also got spiritedly competitive with our annual team pumpkin carving competition 😄🎃 Who knew plant scientists were such talented artists? 🪚🎃🌿

Collage of 13 pumpkins that have been carved in various designs and painted for the annual SLCU Pumpkin Carving Competition

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Andy Posbe @adnroide.bsky.social · 30/10/2025

Spooky season has arrived! 👻 We held our annual Pumpkin Carving Competition at @thesainsburylab.bsky.social —vote for your favourite carve! 🎃🕯️

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Reposted by Andy Posbe

Clémence Marchal @clemmar.bsky.social · 04/09/2025

Super excited and honoured to have been awarded an ERC Starting Grant for CooPAIRation! How do plant immune receptors work together to trigger an immune response? Can we modulate immune responses for disease resistance? We will tackle these questions in CooPAIRation Positions to be announced soon!

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Reposted by Andy Posbe

Josh Bennett @joshwbennett.bsky.social · 14/07/2025

Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾 Come chat to me at my poster on Tuesday, P-050! 📜 If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!

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Reposted by Andy Posbe

Morgan Carter @morgancarterphd.bsky.social · 13/07/2025

Incredibly inspiring talk about the discovery of the more than 200 immune systems in bacteria by Rotem Sorek. From computational discovery in 2018 through functional and structural analyses, even linking bacterial immune systems to that of eukaryotes. #2025ISMPMI

A large conference stage with a man presenting with a power point slide showing a scientific figure about bacterial immunity

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Reposted by Andy Posbe

Current Biology @currentbiology.bsky.social · 19/11/2024

You asked for it...

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Reposted by Andy Posbe

Angus Bucknell @ahbucknell.com · 26/10/2023

Great time at the TSL student/postdoc pumpkin carving social today! 🎃 📸 by Matt Wengler

25 carved pumpkins in a line lit with tea lights. The reflection of the pumpkins can be seen in the water of a pond in front of them.

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