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Stéphane Hacquard

@hacquardst.bsky.social
1.4K followers 236 following 9 posts

Research Group Leader at the MPI for Plant Breeding Research. Interested in plant-microbiota interactions.

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Reposted by Stéphane Hacquard
Nature Microbiology @natmicrobiol.nature.com · 05/10/2026
Out Now! Thiamine cross-feeding drives microbial coexistence in the leaf microbiome #MicroSky
go.nature.com
Thiamine cross-feeding drives microbial coexistence in the leaf microbiome
Nature Microbiology, Published online: 05 October 2026; doi:10.1038/s41564-026-02499-wEvolution of nutrient cross-feeding between a yeast and oomycete mediates microbial coexistence and leaf microbiome stability.
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Nature Microbiology @natmicrobiol.nature.com · 01/10/2026
Out Now! Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts #MicroSky
go.nature.com
Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts
Nature Microbiology, Published online: 01 October 2026; doi:10.1038/s41564-026-02492-3Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.
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Fantin Mesny @mesny.bsky.social · 01/10/2026
5 years ago, @hacquardst.bsky.social and I became very interested in 𝑃𝑙𝑒𝑐𝑡𝑜𝑠𝑝ℎ𝑎𝑒𝑟𝑒𝑙𝑙𝑎 𝑐𝑢𝑐𝑢𝑚𝑒𝑟𝑖𝑛𝑎, an emerging fungal pathogen that colonizes the roots of many plants 🌱 🍅 🌾 🆕📝 Final result of a huge team effort to uncover the bases of its multi-host compatibility👇 www.nature.com/articles/s41...
nature.com
Carbohydrate-active enzymes from a core root mycobiota member enable infection of multiple plant hosts - Nature Microbiology
Host-induced fungal CAZymes act as disease determinants and drive multihost compatibility.
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bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 02/12/2025
Genetic factors driving multi-host infection in a core member of the root mycobiota www.biorxiv.org/content/10.1101/202…
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Clémence Marchal @clemmar.bsky.social · 04/09/2025
Super excited and honoured to have been awarded an ERC Starting Grant for CooPAIRation! How do plant immune receptors work together to trigger an immune response? Can we modulate immune responses for disease resistance? We will tackle these questions in CooPAIRation Positions to be announced soon!
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Fantin Mesny @mesny.bsky.social · 15/08/2025
📣 NEW PREPRINT 📝 We identified evolutionary origins of many fungal effectors! We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression. www.biorxiv.org/content/10.1... cc @teamthomma.bsky.social
biorxiv.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
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Fantin Mesny @mesny.bsky.social · 20/07/2025
Coming back from 5 days of great science at #2025ISMPMI, I wanted to share some of my highlights, and particularly to mention my favourite presentations by early career researchers. A thread 🧵 ⬇️
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Kenichi Tsuda @kenichitsuda.bsky.social · 18/07/2025
I'm very happy that this paper is now published in PNAS! Isochorismate-based salicylic acid biosynthesis appears to have emerged in the Brassicales after the divergence of C. papaya, likely within the timeframe between the divergence of B. maritima and R. odorata. www.pnas.org/doi/10.1073/...
pnas.org
Emergence of isochorismate-based salicylic acid biosynthesis within Brassicales | PNAS
Salicylic acid (SA) is a major defense phytohormone. In Arabidopsis thaliana, the isochorismate (IC) pathway is the primary route for pathogen-indu...
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kathywippel.bsky.social @kathywippel.bsky.social · 16/07/2025
Our paper on Pseudomonas intra-genus competition in SynComs on Arabidopsis roots is now out @plosbiology.org ! 🎉 If you want to chat about the story, visit poster 374 tomorrow, Thursday #2025ISMPMI journals.plos.org/plosbiology/...
journals.plos.org
Pseudomonas intra-genus competition determines the protective function of synthetic bacterial communities in Arabidopsis thaliana
The plant microbiome can protect its host against detrimental bacterial strains. This study shows that competition among Pseudomonas bacteria in synthetic bacterial communities determines how well the...
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Max Planck Institute for Plant Breeding Research @mpipz.bsky.social · 14/05/2025
Celebrating a new PhD at @mpipz.bsky.social! 🎓 Dr. Ram Sevak Raja Kumar defended her thesis in @hacquardst.bsky.social’s lab. Congrats, and all the best for what’s next! 🌟 #PhDone #PlantScience
The post shows a picture of Ram after successfully passing her viva on a green background with words congratulating him on acquiring the PhD title.
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Max Planck Institute for Plant Breeding Research @mpipz.bsky.social · 10/04/2025
📣Paper Alert! 📣New publication out by @hacquardst.bsky.social and his team on the development of MetaFlowTrain – a new tool to study metabolic exchange and interactions within microbial communities @naturecomms.bsky.social 👏🥳Congratulations! 👉https://bit.ly/44jnM1H www.nature.com/articles/s41...
nature.com
MetaFlowTrain: a highly parallelized and modular fluidic system for studying exometabolite-mediated inter-organismal interactions - Nature Communications
Metabolic interactions shape ecosystems but remain hard to study. Here, authors present MetaFlowTrain, a modular, low-cost fluidic system controlling metabolic fluxes between microbes, and show its va...
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Eoin Brodie @elbrodie.bsky.social · 11/04/2025
Very clever design and nicely presented. 👍
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Eva Stukenbrock @estukenbrock.bsky.social · 11/04/2025
New post doc opportunity in our team at Kiel University in the north of Germany. We are looking for a motivated molecular biologists to unravel plant-microbe interactions in grasses. Please see: www.uni-kiel.de/personal/de/... More to our research and group here: www.environmental-genomics.de
uni-kiel.de
Aktuelle Ausschreibungen
Aktuelle Ausschreibungen
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Emily White @emily-white.bsky.social · 11/04/2025
Come and work with me! The Nature Micro team is expanding and we're looking for someone to champion microbial ecology, plant micro & related areas for the journal Knowledge of microbial ecology/plant micro is desirable but we're open to applications from all microbiologists Link below 👇
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Johannes Herpell @herpell.bsky.social · 11/04/2025
Would you like to study metabolite-based microbe-microbe or plant-microbe interactions but do not have the tools to? @chesneau-g.bsky.social came up with a simple solution with great potential! Check out our new publication in @naturecomms.bsky.social and Guillaume’s 🧵 below for details👇
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
5/5. MetaFlowTrain confirms that specific bacterial exometabolites, not media depletion, drive microbial antagonism. 🦠 Pseudomonas R401 WT suppresses SynCom growth via known inhibitory exometabolites. ❌ A triple mutant loses inhibitory power.
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
4/5. MetaFlowTrain dissects inter-kingdom microbial interactions via directional exometabolite flow. 🦠 Bacterial SynComs strongly inhibit fungal growth, even without physical contact. 🚫 Up to 82% growth suppression via exometabolites.
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
3/5. MetaFlowTrain reveals how soil conditioning alters microbial assembly/exometabolite output. 🦠 SynComs exposed to plant-conditioned peat undergo major community shifts & consume key metabolites (α-KG, fumarate). 🌱 BF SynCom-derived exometabolites impact Arabidopsis germination & root growth.
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
2/5. MetaFlowTrain cultivates diverse microbes & collects their exometabolites under continuous nutrient flow. 🌱 Using sterile peat extract, we grew 11 bacterial & 4 fungal strains from the Arabidopsis root microbiota. 💥 Exometabolite profiles differed significantly by strain.
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
📝 Paper: www.nature.com/articles/s41... 1/5. 🚂 MetaFlowTrain = 4 modular components: a. Variety of liquid inputs b. 24-channel pump enabling parallel metabolic trains c. 3D-printed gnotobiotic microchambers d. Multi-layered outputs for cell/metabolite analysis 🔗 protocols.io/view/36wgqd68ovk5/v3
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Guillaume Chesneau @chesneau-g.bsky.social · 11/04/2025
🚨Excited to share our new publication! MetaFlowTrain, a highly parallelized and modular fluidic system to study exometabolite interactions between microbes-microbes-plants 🌱 @hacquardst.bsky.social @herpell.bsky.social S.Wolf S.Perin @mpipz.bsky.social www.youtube.com/watch?v=gNUf... 🧵Thread 5/5:
youtube.com
MetaFlowTrain : A Highly-Parallelized and Modular Fluidic System.
YouTube video by Guillaume Chesneau
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Stéphane Hacquard @hacquardst.bsky.social · 10/04/2025
We present MetaFlowTrain, an easy-to-build, highly parallelized, and cost-effective fluidic system for studying microbial exometabolites and their roles in modulating microbe–microbe–host interactions. Kudos to @chesneau-g.bsky.social @mpipz.bsky.social Give it a try: www.nature.com/articles/s41...
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Prof Braj Singh @prof-braj-singh.bsky.social · 06/04/2025
New paper from lab- in @newphyt.bsky.social Integrating ecological and evolutionary frameworks for SynCom success. Led by @manudelbaq.bsky.social with Singh, Liu, Sáez-Sandino, Coleine, Muñoz-Rojas, Bastida, Trivedi @microsky.bsky.social nph.onlinelibrary.wiley.com/doi/full/10....
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Tonni Andersen @tonnigrubeandersen.bsky.social · 21/03/2025
Finally! Im so excited to present to culmination of many years of work from the fantastic Defeng Shen and some great collaborators. For details, I have made a digested thread below, but if you are more interested feel free to reach out (and read the paper of course). www.science.org/doi/10.1126/...
science.org
Apoplastic barriers are essential for nodule formation and nitrogen fixation in Lotus japonicus
Establishment of the apoplastic root barrier known as the Casparian strip occurs early in root development. In legumes, this area overlaps with nitrogen-fixing nodule formation, which raises the possi...
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Roman Ulm @romanulm.bsky.social · 19/02/2025
POSTDOC POSITION AVAILABLE, UV-B Perception and Signalling, Geneva, Switzerland. Deadline approaching: 24.02.2025
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Paloma Durán @paduba.bsky.social · 17/02/2025
Happy to share this viewpoint, written together with @fabriceroux7.bsky.social and Fabienne Vailleau @lipme-toulouse.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/... 1/4
nph.onlinelibrary.wiley.com
Building microbial synthetic communities: get inspired by the design of synthetic plant communities
In the last decade, the generation of host-associated microbial culture collections has allowed the fine disentangling of complex relationships between commensal microbes and their hosts, and within-...
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Chloé Beaulieu @chloe-beaulieu.bsky.social · 17/02/2025
I’m super happy to have a great part of my PhD work (under the wonderful supervision of C. Libourel @pierremarcdelaux.bsky.social & @maximebonhomme.bsky.social) now out in @naturegenet.bsky.social ! Here’s a little thread (1/18) www.nature.com/articles/s41...
nature.com
The Marchantia polymorpha pangenome reveals ancient mechanisms of plant adaptation to the environment - Nature Genetics
Pangenome analyses of 133 wild accessions of the model bryophyte Marchantia polymorpha identify adaptive features and provide insights into the mechanisms of plant adaptation to the terrestrial enviro...
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PM Delaux @pierremarcdelaux.bsky.social · 17/02/2025
1/6 Super excited to share with you our work on Marchantia intra-specific diversity and pan-genomics, just out @naturegenet.bsky.social www.nature.com/articles/s41... Everything on the discoveries in the thread by @chloe-beaulieu.bsky.social I want to emphasize 5 additional points:
nature.com
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Yasin Dagdas @plantophagy.bsky.social · 07/02/2025
Happy to see that our Cell wall integrity #CWI & #ATG8ylation #preprint found a home @natureplants www.nature.com/articles/s41... Congrats Jose, Peng, Alessia & everyone involved. Stay tuned for exciting updates on this story…
nature.com
ATG8ylation of vacuolar membrane protects plants against cell wall damage - Nature Plants
ATG8ylation of the tonoplast, triggered by cell wall damage, acts as a vital vacuolar quality control mechanism that safeguards vacuolar integrity and ensures cell survival under stress.
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Tatsuya Nobori @tatsuyanobori.bsky.social · 08/01/2025
New year, new paper! Now published in @nature.com. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in the Ecker lab at @salkinstitute.bsky.social. A thread (0/n) #PlantScience www.nature.com/articles/s41...
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André Marques @amarques.bsky.social · 07/01/2025
Happy to share our Tansley insight published in @newphyt.bsky.social nph.onlinelibrary.wiley.com/doi/epdf/10.... #plantscience #chromosome #centromere #meiosis
nph.onlinelibrary.wiley.com
Centromere diversity and its evolutionary impacts on plant karyotypes and plant reproduction
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Roeland Berendsen @rlberendsen.bsky.social · 28/12/2024
www.nature.com/articles/s41... 🌱🚜 Excited to see our paper in @naturemicrobiol.bsky.social ! Amazing effort by @y-song.bsky.social in collaboration with TU Delft (Neil Budko, Elisa Atza) and the Dutch potato breeding industry to harness the power of the microbiome! 🥔🔬@utrechtpmi.bsky.social
nature.com
Seed tuber microbiome can predict growth potential of potato varieties - Nature Microbiology
Time-resolved drone imaging of potato crop development and seed tuber microbiome data can be used to predict potato vigour, or growth potential, in next-season crops in trial fields.
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Team_Zuccaro @algazuccaro.bsky.social · 27/11/2024
Our latest paper is online: "A nucleoside signal generated by a fungal endophyte regulates host cell death and promotes root colonization". Two fungal enzymes acting cooperatively are key players in this process. Thanks to the fantastic team of scientists. 👇 www.sciencedirect.com/science/arti...
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Liz Koziol @lizkoziol.bsky.social · 21/11/2024
🌾🌱🧪🦠🌍 New study out today! Please share! Meta-analysis of 302 globally sourced AMF inoculant trials. Only 12% of commercial products both boosted crop growth and had effective root colonization by mycorrhizal fungi. #soilscience #PlantScience #mycosky nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com
Meta‐analysis reveals globally sourced commercial mycorrhizal inoculants fall short
Click on the article title to read more.
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François Leulier @francoisleulier.bsky.social · 22/11/2024
A top european science job opened to applications: Scientific director @pasteur.fr research.pasteur.fr/en/job/insti...
research.pasteur.fr
The Institut Pasteur is looking for a Scientific Director | Research - Institut Pasteur
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Karin Sauer @biofilms-karin.bsky.social · 22/11/2024
And check out the #FEMS thematic issue on microbiome interactions academic.oup.com/femsre/pages... that was edited by my Co-editor-in-chief Bart Thomma, @teamthomma.bsky.social
academic.oup.com
Thematic Issue: Microbiome interactions across host species
This cutting-edge collection explores the different facets of microbiome interactions across host species, covering a wide range of subtopics. Browse the paper
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Asaf Levy @asaflevylab.bsky.social · 16/11/2024
This is a recent cool preprint by Dor Russ et al. from Jeff Dangl's lab showing several bacterial genes that affect colonization of a single (plant) host and organ. www.biorxiv.org/content/10.1... Are you familiar with other bacterial genes that have similar host- or organ-specific function?
biorxiv.org
An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxification of a host-specific glucosinolate
In nature, plants recruit a diverse microbial community, the plant microbiome, that is distinct from the surrounding soil community. To understand the forces that shape the plant microbiome we need to...
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New Phytologist @newphyt.bsky.social · 15/11/2024
We are delighted to announce that Maarja Öpik will be New Phytologist's next Editor-in-Chief. Maarja will take up the position from January 2025, for an initial term of five years. www.newphytologist.org/news/view/354
Maarja Öpik
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Paloma Durán @paduba.bsky.social · 12/11/2024
The ECOGEN team @lipme-inrae.bsky.social is searching for 3! PostDocs to join us in the PATHOCOM ERCSyg project in Toulouse, investigating the impact of host and microbial genetics on plant pathogen-pathogen interactions. The links to apply are below. Deadline 29th of Nov!!
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Tiffany Lowe-Power stands with Minnesota @tlowepower.bsky.social · 10/11/2024
I initiated a plant pathology/plant microbe starter pack, feel free to self-nominate 🥀 go.bsky.app/LbYaW8k
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Marc Somssich @somssich.bsky.social · 11/11/2024
Hello new Plant Scientists, 2 Things: 👉 To connect to 150 Plant Science Accounts and 3 relevent feeds, here's a #StarterPack for you: go.bsky.app/8Zfmwf7 👉 To get your #PlantScience posts into the Plant Science Research Feed (here: bsky.app/profile/did:...), always use the Hashtag #PlantScience
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Marc Somssich @somssich.bsky.social · 07/11/2024
📜 From synthetic communities to synthetic ecosystems: exploring causalities in plant–microbe–environment interactions 🧑‍🔬 Guillaume Chesneau, Stéphane Hacquard, et al 📔 @newphyt.bsky.social 🔗 nph.onlinelibrary.wiley.com/doi/10.1111/... #️⃣ #PlantScience #PlantImmunity #PlantMicrobiome #TansleyReview
nph.onlinelibrary.wiley.com
From synthetic communities to synthetic ecosystems: exploring causalities in plant–microbe–environment interactions
The plant microbiota research field has rapidly shifted from efforts aimed at gaining a descriptive understanding of microbiota composition to a focus on acquiring mechanistic insights into microbiot....
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raphmercier.bsky.social @raphmercier.bsky.social · 10/11/2024
The department of Chromosome Biology of the Max planck @mpipz_cologne is looking for a new group leader. Join us, with @Polina_Novik @marques_et_al @LabSchneeberger We are very open minded concerning the project, it just needs to be exciting. jobs.mpipz.mpg.de/jobposting/8...
jobs.mpipz.mpg.de
Group Leader Position in Plant Chromosome Biology (m/f/d)
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