Background : The growing availability of large prokaryotic genomic datasets presents an opportunity to discover new metabolic pathways and enzymatic reactions useful for industrial or synthetic…

Plasmodium falciparum possesses a highly structured genome with extensive sequence diversity concentrated in Variant Surface Antigen (VSA) families. These genes—var, rif, and stevor—play key roles in…

The current academic publishing system faces many well-identified issues. Not only is it slow and costly, but it is also an opaque system that produces a substantial amount of non-reproducible…

High-quality reference genomes are increasingly recognized as essential resources in biodiversity genomics and conservation. However, successful DNA extraction and long-read sequencing remain highly…

5' and 3' RNA-end sequencing protocols have unlocked new opportunities to study aspects of RNA metabolism such as synthesis, maturation and degradation, by enabling the quantification of exact ends…

Circular RNAs (circRNAs) are unique non-coding RNAs with covalently closed loop structures formed through backsplicing events. Their stability, tissue-specific expression patterns, and potential as…

Trichoderma gamsii is a filamentous fungus widely recognized for its beneficial roles in agriculture, particularly for its ability to suppress plant pathogens and enhance crop health. However,…

<div><p>Assessing ecological quality (EQ) is crucial for marine biodiversity monitoring. With the advent of High-Throughput Sequencing technologies, metabarcoding has enabled large-scale microbial…

At the onset of bacterial chromosome replication initiation, replicative helicases are loaded onto DNA, a process requiring helicase loaders. While organisms documented as lacking a helicase loader…

Due to the costs of single-cell sequencing, sample sizes are often relatively limited, sometimes leading to poorly reproducible results. In many contexts, however, larger bulk RNAseq data is…

Genomes from bacteria of interest to the food industry exhibit significant functional variability, yet evaluating this characteristic remains challenging. As public repositories continue to…

The increasing availability of genome sequences has highlighted the limitations of using a single reference genome to represent the diversity within a species. Pangenomes, encompassing the genomic…

Despite the inherent challenge of finding suitable mating partners, most eukaryotes use sexual reproduction to produce offspring endowed with increase genetic diversity and fitness. The persistence…

Peer Community in Psychology

We present a reference genome assembly from an individual male Violet Carpenter Bee (Xylocopa violacea, Linnaeus 1758). The assembly is 1.02 gigabases in span. 48% of the assembly is scaffolded into…

For 9 years now, thanks to your involvement, SciPost has grown into being recognized as an essential open science infrastructure. We are often touted as a template for journals of the future and case…

Transposable elements (TEs) have an important role in genome evolution but are challenging for bioinformatics detection due to their repetitive nature and ability to move and replicate within…

Cydalima perspectalis (the box tree moth), Leptoglossus occidentalis (the western conifer seed bug), and Tecia solanivora (the Guatemalan tuber moth) are three economically harmful invasive insect…

Francis et al. (2025) investigate the relationship between genomic rearrangement, specifically macro- and micro-synteny, and speciation across a broad range of animal phyla. Using chromosome-level…

We present haplotype-resolved whole-genome assemblies from one individual European river lamprey ( Lampetra fluviatilis ) and one individual brook lamprey ( Lampetra planeri ), usually regarded as…

The study of genomic variability within and between populations, as well as among species, relies on comparative analyses of homologous positions—sites that share a common evolutionary origin.…

Mediation analysis plays a crucial role in epidemiology, unraveling the intricate path- ways through which exposures exert influence on health outcomes. Recent advances in high-throughput sequencing…

Reviews

Fekete et al. (2024) generated a chromosome-level reference genome assembly for the mountain hare (Lepus timidus). This represents a significant advancement in genomic research for non-model…

Fekete et al. (2024) generated a chromosome-level reference genome assembly for the mountain hare (Lepus timidus). This represents a significant advancement in genomic research for non-model…