The rapid evolution of plant pathogens poses a persistent threat to global agricultural sustainability, often outpacing the discovery and deployment of natural disease resistance genes. While bioengin...

Transcription in chloroplasts depends on the Plastid-Encoded RNA polymerase (PEP), a bacterial-derived enzyme whose catalytic core remains encoded by the highly reduced genome inherited from the cyano...

In Mueller et al. the authors capture and visualize the native enzyme-substrate (Michaelis) and product complexes of nucleotide addition by bacterial RNA polymerase. Substrate coordination in a transition-state-like conformation, together with highly coordinated water molecules, suggests a positional (entropic) catalytic mechanism involving specific acid-base chemistry.

An exciting opportunity has arisen for a Postdoctoral Researcher to join the newly starting Schreier group at the John Innes Centre, working on cutting-edge science in the field of photosynthesis…

PhD Project - Engineering plant rubisco enzymes through high-throughput enzyme assays and cryo-EM (Plant BioDesign Cambridge project) at University of York, listed on FindAPhD.com

We discover and study reverse transcriptases

Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…

The University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This...

The innovative research project of an early-career plant scientist at the John Innes Centre has attracted a prestigious funding award from a global health charity…

An exciting opportunity has arisen for an Optical Microscopy Support Specialist to join the Bioimaging Platform at the John Innes Centre.

The John Innes Centre (JIC) seeks a visionary Group Leader to lead research on Discovery Plant Science.

Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs). In the budding ...

Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Following an international search, Professor Cristóbal Uauy has been appointed as the next Director of the John Innes Centre. Professor Uauy is internationally recognised for his significant…

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...

Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...