Nature Reviews Microbiology, Published online: 02 May 2025; doi:10.1038/s41579-025-01180-zIn this Review, van de Veerdonk and colleagues explore Aspergillus fumigatus biology, the host immune responses and the fungal mechanisms of immune evasion, as well as emerging challenges such as virus-associated pulmonary aspergillosis and azole resistance, and reflect on future directions for therapeutics and patient care improvement.

To combat long-overlooked fungal pathogens, researchers and regulators must embrace innovative science and policy.

La bande dessinée InScience : cultive ta santé avec l’Inserm ! nous entraîne au cœur de la recherche biomédicale, avec pédagogie et humour. Ses deux tomes, écrits et dessinés par Maïté Robert, sont ac...

Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But scientists have only begun to unlock the secrets of this ancient arms race.

Abstract. Textbooks remain a primary source of reference and education for many health care professionals and students. This study assessed the mycology co

Traditional peer review is slow, often delayed by the time-consuming process of identifying reviewers and lengthy review turnaround times. This study tests the feasibility of the Fast & Fair peer revi...

In red are the proposed improvements to the classical yeast transformation protocol.

« Je ne serais pas arrivée là si… » Chaque semaine, « Le Monde » interroge une personnalité sur un moment décisif de son existence. La chercheuse franco-britannique, professeure au Collège de France, ...

Genome-wide hypertranscription is common in human cancer and predicts poor prognosis. To understand how hypertranscription might drive cancer, we applied our formalin-fixed paraffin-embedded (FFPE)–cl...

Shen et al. investigate the use of Lactobacillus plantarum, a commensal bacterial strain, as a chassis for targeting the olfactory mucosa to facilitate precise nose-to-brain delivery of therapeutic mo...

Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that proteins with shared functions share amino acid sequence ...

SUMMARYThe ability to overcome metabolic stress is a major determinant of outcomes during infections. Pathogens face nutrient and oxygen deprivation in host niches and during their encounter with immu...

The fungal BET protein Bdf1 is a potential antifungal target in pathogenic Candida species requiring the inhibition of both its bromodomains. Humanized Candida strains and NanoBiT complementation ass...

Researchers with lived experience of the chronic workplace stress that typifies burnout describe how they sought help and turned their working lives around.

Survey of more than 1,600 biomedical researchers also flagged small sample sizes and cherry-picking of data as leading causes of reproducibility problems.

Nshanian et al. investigate the differential effects of the short-chain fatty acids propionate and butyrate on chromatin remodelling and gain insight into the mechanisms that drive selective histone a...

As HBO finally confirms the release date of The Last of Us season two, scientists say the show's premise could soon be a reality - and disasters like the California wildfires could be to blame.

Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...

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