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Mehmet Can Uçar

@mehmetcanucar.bsky.social
614 followers 499 following 67 posts

Research fellow @sheffielduni.bsky.social • Physics of biological and living matter Alumnus @istaresearch.bsky.social (Postdoc) & @mpici.bsky.social (PhD) www.sheffield.ac.uk/mps/people/all-…

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Reposted by Mehmet Can Uçar
Brian Camley @diffusiveblob.bsky.social · 21/09/2026
Come join us! The Jenkins Department of Biophysics at Johns Hopkins University is hiring for *computation and theory* - multiple positions at all levels www.linkedin.com/posts/brian-...
linkedin.com
Home | Brian Camley
Multiple Faculty Positions in Biophysics Theory and Computation at All Levels    Come join JHU Biophysics! The Thomas C. Jenkins Department of Biophysics (https://lnkd.in/eD8NJKgh) invites application...
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Ricard Alert Zenón @ricardalert.bsky.social · 08/09/2026
New paper out @natcellbio.nature.com! In embryos, immune cell migration is guided by the surrounding tissue flow. In turn, tissue flow is captured by active wetting theory, generalized to include influx from the upper cell aggregate! Check the thread below! 👇 www.nature.com/articles/s41...
nature.com
Tissue flow acts as a guidance cue for immune cell polarization and directional migration - Nature Cell Biology
Le et al. show that in Xenopus embryos, local ectodermal tissue flows provide a directional cue that polarizes and guides embryonic myeloid cells migration via cell-on-cell interactions.
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Yuting Irene Li @irene-yuting-li.bsky.social · 27/07/2026
I’m starting at the Hubrecht Institute at a new group leader from September. I will be hiring a PhD student through the PhD program ⬇️ If you, or anyone you know, is interested in theoretical biophysics, I will be very excited to hear from them — please send inquiries to my ISTA email for now :)
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Alfonso Martinez Arias @amartinezarias.bsky.social · 07/07/2026
This www.nature.com/articles/s41... is a very troublesome paper. Either human embryos are totally different from other mammals or there is a problem with this specimen. In either case @Nature should have been cautious.
nature.com
Epiblast diversification and blood formation in a human pregastrula - Nature
High-resolution spatial transcriptome analysis of a human embryo at Carnegie stage 6 reveals three distinct developmental trajectories from the epiblast towards amnion, primitive streak and axial meso...
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Rory Cooper @rorylcooper.bsky.social · 02/07/2026
Check out this new work from the Towers lab to learn how avian digit patterns can be transformed into mammalian-like patterns! 🔬🐣🧪 @matt-towers.bsky.social Video: www.youtube.com/watch?v=fvL_... Preprint: www.biorxiv.org/content/10.6...
youtube.com
Transforming Avian to Mammalian Modes of Digit Patterning
YouTube video by Matteo de la Torre
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Robert Insall @robinsall.bsky.social · 24/06/2026
It neglects that "the best" science is never, *ever* a single parameter. It neglects that science is a rapidly-evolving concept, the way it is published changes by the year, and the definition of success only exists in long hindsight. Above all it neglects that science is a human construct.
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 17/05/2026
🧪⚛️ Immune cells in the retina self-organize into efficient territories right before the eye opens! 😳 Surprisingly, this also drives the emergence of a “hidden” long-range order called hyperuniformity. Thread below ⬇️
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 08/05/2026
Summer is coming, but how will you maximize your picnic space when everyone else is doing the same? In our new preprint, we show that branched cells may have an elegant solution: As cells grow and repel neighbors, they don't just cover space, but reach a hidden order called hyperuniformity! 🧪⚛️
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 08/05/2026
Summer is coming, but how will you maximize your picnic space when everyone else is doing the same? In our new preprint, we show that branched cells may have an elegant solution: As cells grow and repel neighbors, they don't just cover space, but reach a hidden order called hyperuniformity! 🧪⚛️
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David Brückner @davidbrueckner.bsky.social · 21/04/2026
If you're looking for a PhD position, or know someone looking checkout our PhD Fellowship program! Deadline May 8th. We are always looking for talented students with a physics or computational background to join our group to work on the physics of living systems! More info here: shorturl.at/ebGVr
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Alex Gao @algao.bsky.social · 16/04/2026
Excited to share our new findings in @science.org on how the DRT3 bacterial defense system uses a reverse transcriptase that builds DNA repeats without a nucleic acid template. Microbes never cease to amaze! www.science.org/doi/10.1126/...
science.org
Science | AAAS
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Denis Wirtz @deniswirtz.bsky.social · 14/04/2026
Mapping nerves in a whole embryos. We find that across species and development stages, embryonic nerves display (beautiful) fractal geometry. More here: www.biorxiv.org/content/10.6...
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canaztekin.bsky.social @canaztekin.bsky.social · 10/04/2026
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders? In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸 🔗 www.science.org/doi/10.1126/... #EvoDevo
science.org
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...
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Robert Insall @robinsall.bsky.social · 03/04/2026
New paper! Self-generated gradients in macrophage chemotaxis. Just published, by the esteemed Abhi Kiran and many collaborators. A short skytorial follows. journals.plos.org/plosbiology/...
journals.plos.org
Macrophages self-generate and refine chemotactic gradients during migration towards complement C5a
Macrophages don’t just follow chemoattractants to locate sites of infection, they can also create and sculpt them as guidance cues but the mechanisms remain unclear. This study shows that macrophages ...
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Anestis Tsakiridis @tsakiridis.bsky.social · 13/02/2026
2 weeks to go until the registration/abstract submission deadline for our @cclguk.bsky.social @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk this June. Great speaker line up and slots for short talks: www.cclg.org.uk/information-...
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
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Ricard Alert Zenón @ricardalert.bsky.social · 30/01/2026
New preprint! We show how mesoscopic nonequilibrium fluctuations in active gels emerge from the breaking of detailed balance at the molecular scale. Warning: Long technical paper ahead! Enjoy! @mpipks.bsky.social @ub.edu @ubics.bsky.social @icreacommunity.bsky.social arxiv.org/abs/2601.20483
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Alice Auersperg @auersperga.bsky.social · 19/01/2026
Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments. www.cell.com/current-biol...
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David Brückner @davidbrueckner.bsky.social · 06/01/2026
Self-organized or instructed? My @natrevgenet.nature.com Journal Club traces how classic papers revealed two modes of developmental patterning & why the debate between Turing and Wolpert is as timely as ever for organoid engineering today www.nature.com/articles/s41...
nature.com
From models to molecules: self-organized and instructed modes of developmental patterning - Nature Reviews Genetics
In this Journal Club article, David Brückner discusses how seminal molecular genetic studies by Driever and Nüsslein-Volhard and Sick et al. demonstrated that both instructed (Wolpert model) and self-...
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Maik Bischoff @maikbischoff.bsky.social · 26/06/2025
Morphogenesis & Organogenesis! Part 1 (full) in the comments 👇 Comment if you'd like to be added (regardless of age or career stage!) Please post your own biology-related starter packs using #BioStarterPacks 🧬🔬🪰🐟🐁🌱
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 05/12/2025
cytoskeletal filaments patterning musée d’Orsay!
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Sophien Kamoun @kamounlab.bsky.social · 03/12/2025
I just published: ERC-Plus: jackpot science or missed chance to fix academia? My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building. medium.com/p/erc-plus-j...
medium.com
ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re…
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Ricard Alert Zenón @ricardalert.bsky.social · 02/12/2025
New preprint! Do you like ocean waves? We found similar waves on bacterial colonies! We found that this collective behavior, known as rippling, is nothing but surface waves on an active nematic. @princeton.edu @mpipks.bsky.social @ub.edu @icreacommunity.bsky.social www.biorxiv.org/content/10.1...
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jsimmchen.bsky.social @jsimmchen.bsky.social · 29/10/2025
In May 2024 we had a great workshop on chemotaxis in the MPI PKS in Dresden! The social impressions are in the picture below, and the scientific discussions are summarised in Angewandte Chemie lnkd.in/d6ymRhGK What a nice way to remember!
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AlankoLab @alankolab.bsky.social · 28/10/2025
🚨 Postdoc opportunities in Finland! Are you fascinated by leukocyte navigation and chemotaxis in different disease and tissue contexts? Apply for a 3-year postdoc fellowship with us! More info below 👇 or DM me.
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efe ilker @efeilker-phys.bsky.social · 27/10/2025
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176 #biophysics
euraxess.ec.europa.eu
Postdoc in Theoretical Biophysics
Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).
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David Brückner @davidbrueckner.bsky.social · 16/10/2025
🤔 Can tissue patterning & tumor heterogeneity emerge in a self-organized way? We show that self-organized mechanical stress & density gradients pattern tumors in vitro & in vivo, and this behavior is quantitatively predicted by a mechano-chemical active fluid model! Check out Carlos' thread ⬇️
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Lale Alpar, PhD @lale-alpar.bsky.social · 02/10/2025
Thought it would be fitting for my first post to be this little fly illustration I made. Because once a Drosophilist, always a Drosophilist 🪰
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David Brückner @davidbrueckner.bsky.social · 27/09/2025
How do cells navigate up gradients of adhesive proteins? 🤔 Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood We show that passive friction directs cells & explains complex trajectories on gradients 👉 www.nature.com/articles/s41...
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Matt Towers @matt-towers.bsky.social · 09/09/2025
I'm a bit late to the party over here. I'll be advertising a BBSRC-funded postdoc position soon. So if anyone wants to solve some outstanding questions in limb development - please get in touch. We have a variety of models and approaches (everything from stem cells to sharks). towerslab.weebly.com
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David Brückner @davidbrueckner.bsky.social · 25/08/2025
🤔 Can migrating cells 'remember' their past trajectories? In collab w/ @sgabriele.bsky.social & @kyohalie.bsky.social, we address this question: Confined cells undergo geometry-sensitive morphology switches, and these switches depend on the past migration history! www.nature.com/articles/s41...
nature.com
The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics
Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 22/08/2025
🚨 New paper out in @pnas.org! 🚨 We show that self-generated gradients allow heterogeneous cell mixtures to co-migrate efficiently over long distances —while optimizing their physical interactions! (See below for 🧵) www.pnas.org/doi/10.1073/... 🧪
pnas.org
Self-generated chemotaxis of mixed cell populations | PNAS
Cell and tissue movement in development, cancer invasion, and immune response relies on chemical or mechanical guidance cues. In many systems, this...
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Giorgio Gilestro @giorgio.gilest.ro · 12/05/2025
This is insane. Labour is making the very same mistake the Tories made but in a more catastrophic way. A left-leaning party adopting an ultra-right fascist agenda: what could go wrong?
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 11/05/2025
Sheffield continues to surprise -I was expecting rain and steel 🥲
Scene from Rivelin valley in SheffieldPeople bathing in the Rivelin river waterfallsView from a hill towards Fox Hagg nature reserveweather forecast for Sheffield
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 07/05/2025
..and the same day we get a definition of what a *good* theory is by @robinsall.bsky.social back here on the island 😅 @sheffielduni.bsky.social
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 04/05/2025
here's a plot showing the increase in the number of persons disappeared by ICE (data as posted by @msbr89.bsky.social):
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Nature @nature.com · 13/04/2025
Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good go.nature.com/42nGQt6
go.nature.com
Why an overreliance on AI-driven modelling is bad for science
Nature - Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good.
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Dr Cath Feely @cathfeely.bsky.social · 11/04/2025
University of Derby faces mass job cuts as management plans to make half of senior academics redundant. Please spread the word. www.ucu.org.uk/article/1398...
ucu.org.uk
University of Derby staff face mass job cuts as management plans to axe half of senior academics
University of Derby staff face mass job cuts as management plans to axe half of senior academics
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Denis Krndija @deniskrndija.bsky.social · 06/04/2025
🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻‍🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)
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American Historical Association @historians.org · 24/03/2025
The AHA has released a statement condemning "the dismantling of federal departments and agencies through the indiscriminate termination of federal employees and elimination of programs, including historical offices.” 🗃️
historians.org
American Historical Association Condemns Indiscriminate Cuts to the Federal Government
The AHA has released a statement condemning "the dismantling of federal departments and agencies through the indiscriminate termination of federal employees and elimination of programs, including hist...
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Radley Balko @radleybalko.bsky.social · 30/03/2025
NYU canceled a planned speech by the former president of Doctors Without Borders because she planned to discuss the humanitarian crisis in Gaza and cuts to US AID. This is what actual campus censorship looks like.
ctvnews.ca
‘Climate of fear’: Montreal doctor says NYU cancelled her presentation
A Montreal doctor says her presentation at NYU was abruptly cancelled and believes the university did so out of fear of being pressured by the Donald Trump administration.
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Jason Linkins @dceiver.bsky.social · 29/03/2025
another student was disappeared at the University of Minnesota
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Annika Barber @annikabarber.bsky.social · 27/03/2025
How do I even put "my doctoral students could not achieve their full scientific potential because they had to worry ICE would abduct them off the street while getting to lab" into a tenure impact statement?
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Biology Open @biologyopen.bsky.social · 25/03/2025
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Fast & Fair peer review

A new initiative offering high-quality peer review within 7 working days of submission

Biology Open
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Paul Villoutreix @paulvilloutreix.bsky.social · 25/03/2025
Very happy to share our new preprint "MODIS: Multi-Omics Data Integration for Small and Unpaired Datasets"! We proposed a new coupled variational auto-encoder architecture to solve the problem of data integration for small and unpaired datasets (diagonal integration) arxiv.org/abs/2503.18856
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Robert Saunders @robertsaunders.bsky.social · 22/03/2025
It is inherently dangerous to democracy for one man to hold as much wealth and power as Elon Musk. It should be a primary goal of democratic states to prevent such concentrations of power, & to ensure that global plutocrats cannot shut off the arteries of democracy. www.politico.eu/article/musk...
politico.eu
Musk’s X suspends opposition accounts in Turkey amid civil unrest
Suspensions affect accounts spreading information about the widespread demonstrations.
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Yusuf Sarfati @yusufsarfati.bsky.social · 19/03/2025
This should be the last straw for the Turkish opposition. Unless there are mass protests, which the government is trying to prevent at all costs, Turkey is now very much a closed autocracy. www.nytimes.com/2025/03/19/w...
nytimes.com
Turkey Arrests Istanbul Mayor, Key Rival to President Erdogan
Ekrem Imamoglu was detained at his home, according to prosecutors, who said the charges against him were related to corruption and terrorism.
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Hallou Lab @halloulab.bsky.social · 17/03/2025
🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...
nature.com
A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
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David Brückner @davidbrueckner.bsky.social · 14/03/2025
How do cells migrate without substrate, e.g. in embryogenesis, when extra-cellular matrix has not yet formed? Check out our paper in @cp-cellreports.bsky.social on zebrafish lateral mesendoderm migration, led by @stetavano.bsky.social @heisenbergcplab.bsky.social! www.cell.com/cell-reports...
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Jan Steinkühler @steinkuehler.bsky.social · 09/03/2025
Our work about a dynamic tissue mimetic is finally out: Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles @mehmetcanucar.bsky.social @uni-kiel.de www.nature.com/articles/s41...
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Mehmet Can Uçar @mehmetcanucar.bsky.social · 04/03/2025
Very happy to see this out! 😍 Tissue-like lipid networks with motile bacteria undergo large remodeling events, leading to active “hubs” & tissue fluidization! This was a super fun collab w Jan Steinkuhler lab! www.nature.com/articles/s41...
nature.com
Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles - Nature Communications
Constructing synthetic prototissues is a challenge in bottom-up synthetic biology. Here, the authors introduce a “lipid foam” tissue mimetic and demonstrate network-wide tension fluctuations upon comp...
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