Sign in

Anestis Tsakiridis

@tsakiridis.bsky.social
562 followers 612 following 50 posts

Research group leader and Senior Lecturer at the University of Sheffield. Stem cells, embryonic development, disease modelling, regenerative medicine: www.tsakiridislab.com

PostsRepliesMedia
Anestis Tsakiridis @tsakiridis.bsky.social · 21/08/2026
We have an opening for a Medical Research Council-funded, 3-year research assistant post in my lab to contribute to our efforts to develop a cell therapy against Hirschsprung disease. Closing date=15/9, for more details check the application portal: jobsite.sheffield.ac.uk/job/Research...
jobsite.sheffield.ac.uk
Research Assistant (Stem Cell Biology)
Research Assistant (Stem Cell Biology)
045
Reposted by Anestis Tsakiridis
International Society of Developmental Biology @isdb.bsky.social · 19/08/2026
New preprint by @benswedlund.bsky.social shows that simple two-component synthetic reaction-diffusion circuits are sufficient to generate self-organised patterns in mammalian cells. Instead of a diffusing activator, he tethers it to the cell-cell junction 🔥! Check it out: doi.org/10.64898/202...
12510
Reposted by Anestis Tsakiridis
Pablo Navarro @pablonavarrolab.bsky.social · 15/08/2026
Happy to share our last work on mitotic bookmarking where we describe a new role for extensively studied TFs. Heroic effort by first author Inma over many years. genesdev.cshlp.org/content/earl...
genesdev.cshlp.org
Mitotic MAX bookmarking drives MYC-dependent hypertranscription at TBP-bound promoters
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
23311
Reposted by Anestis Tsakiridis
Vicki Metzis @vmetzis.bsky.social · 17/07/2026
How does an embryo generate the right cells in the right place? Delighted to share our latest findings on how neural crest cells acquire vagal or trunk identities Spoiler alert: The timing & combination of CDXs preconfigures cell identity & distinct HOX states www.biorxiv.org/content/10.6...
biorxiv.org
Temporally distinct CDX programmes preconfigure vagal and trunk neural crest
Neural crest cells (NCCs) are progenitor cells vital in establishing the head, heart, gut and peripheral nervous system of vertebrate embryos. Disruptions to NCC development underlie neurocristopathie...
16724
Reposted by Anestis Tsakiridis
Igor Adameyko @adameykolab.bsky.social · 11/07/2026
For the neural crest nerds: we love looking into transcriptional programs in single NCC cells. However, selective ribosomal modifications refine gene expression programs at a different scale. Here is our story about modified ribosomes in neural crest fate selection: www.nature.com/articles/s41...
nature.com
Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage - Nature Communications
Neural crest cells differentiate into skeletogenic mesenchyme and neuro-glial lineages, thereby contributing to craniofacial formation. Here, single-cell analysis of cranial neural crest shows that sp...
0299
Reposted by Anestis Tsakiridis
Candice Fung @candicefung.bsky.social · 11/07/2026
🔬 Bidirectional communication between neurons in the mesentery and ileal myenteric neurons www.biorxiv.org/content/10.6...
Image of a dissected mouse ileum myenteric plexus with mesentery attached. The inset shows a cluster of neurons situated in the mesentery.
3135
Reposted by Anestis Tsakiridis
Matt Towers @matt-towers.bsky.social · 02/07/2026
Pleased to share our latest! We show that the chick limb can be directed to recapitulate key stages in mammalian evolution, providing a unifying model for digit patterning across amniotes. Preprint: www.biorxiv.org/content/10.6... Video summary: www.youtube.com/watch?v=fvL_...
biorxiv.org
Transforming avian to mammalian modes of digit patterning
How a conserved embryonic organiser-the Sonic hedgehog (Shh)-expressing Zone of Polarising Activity (ZPA)-generates diverse limb architectures in amniotes remains a central problem in evolutionary and...
12511
Reposted by Anestis Tsakiridis
Karen J Liu @karenjliu.bsky.social · 04/06/2026
Looking forward to an exciting programme this Monday on Developmental Origins of Paediatric Cancers, sponsored by CCLG at the Crick. @tsakiridis.bsky.social www.cclg.org.uk/information-...
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
141
Anestis Tsakiridis @tsakiridis.bsky.social · 18/05/2026
The registration deadline for our @cclguk.bsky.social symposium on the developmental origins of paediatric cancers is closing this Friday 22nd May. A wide range of topics and a stellar speaker line-up so make sure you register! for more details check: www.cclg.org.uk/information-...
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
031
Reposted by Anestis Tsakiridis
Roberto Mayor Lab @mayorlab.bsky.social · 16/05/2026
PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl
06857
Reposted by Anestis Tsakiridis
Development @dev-journal.bsky.social · 12/05/2026
Did you know that Development publishes Research Reports? These short articles emphasise an important finding, laying the groundwork for future research. Browse a selection of our latest, free-to-read Research Report highlights in our subject collection journals.biologists.com/dev/collecti...
A screenshot of Development's 'Highlights from our Research Reports section' subject collection.
086
Anestis Tsakiridis @tsakiridis.bsky.social · 11/05/2026
The program for our @cclguk.bsky.social symposium, co-sponsored by @dmmjournal.bsky.social , @neuroblastomauk.bsky.social and @parse.bsky.social on the developmental origins of paediatric cancer is now finalised (8th June, @crick.ac.uk): www.cclg.org.uk/information-...
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
151
Reposted by Anestis Tsakiridis
Mehmet Can Uçar @mehmetcanucar.bsky.social · 08/05/2026
Summer is coming, but how will you maximize your picnic space when everyone else is doing the same? In our new preprint, we show that branched cells may have an elegant solution: As cells grow and repel neighbors, they don't just cover space, but reach a hidden order called hyperuniformity! 🧪⚛️
2217
Reposted by Anestis Tsakiridis
Carmen Moreno Gonzalez @carmenmorenogon.bsky.social · 08/05/2026
I’m beyond happy to share that the preprint summarising my PhD research is now online on bioRxiv! 🚀 I am very grateful to my supervisors, Karen J Liu and Andrea Serio, all the coauthors and members of both teams who have made this work possible.
253
Anestis Tsakiridis @tsakiridis.bsky.social · 06/05/2026
Congratulations to @carmenmorenogon.bsky.social, @andreaserio.bsky.social, @karenjliu.bsky.social and the rest of the team for developing a great platform for interrogating neural crest behaviour
031
Anestis Tsakiridis @tsakiridis.bsky.social · 05/05/2026
Our latest preprint is out: we used hPSC differentiation and quantitative modelling to dissect the role of Notch signalling, a pathway that is perturbed in Hirschsprung disease, a potentially lethal enteric neuropathy, in human enteric nervous system (ENS) progenitor dynamics (1/n)
192
Anestis Tsakiridis @tsakiridis.bsky.social · 17/04/2026
Our excursion into the world of hPSC-derived lateral plate mesoderm progenitors, the result of a great collaboration with the lab of @matt-towers.bsky.social. For more details check the thread of @sudeuyulgan.bsky.social below-Sude has been fantastic in leading and driving this work!
1103
Reposted by Anestis Tsakiridis
Surfin' NuRD @surfinnurd.bsky.social · 02/04/2026
Do you do a PhD on Chromatin in this cool critter? Work with @jordisolana.bsky.social @seanflynn.bsky.social, Magda Strauss and myself @lsiexeter.bsky.social on developing #singlecell #chromatin analyses to better understand pluripotency #planarians. www.exeter.ac.uk/research/ins...
Image of a planarian, from Wiki.
21910
Reposted by Anestis Tsakiridis
Luke Dunning @luketdunning.bsky.social · 26/03/2026
Come and join us!! www.jobs.ac.uk/job/DQZ547/r...
jobs.ac.uk
Research Associate - Plant Phylogenomics at University of Sheffield
Apply for the Research Associate - Plant Phylogenomics role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
01921
Anestis Tsakiridis @tsakiridis.bsky.social · 19/03/2026
One day left until the abstract submission deadline for our symposium on the developmental origins of paediatric cancers on the 8th of June! If you do not want to submit an abstract please note that there is still time to register after the 20th of March
032
Anestis Tsakiridis @tsakiridis.bsky.social · 13/03/2026
One week left until the abstract submission deadline for our symposium on the developmental origins of paediatric cancers on the 8th of June!
043
Anestis Tsakiridis @tsakiridis.bsky.social · 06/03/2026
Abstract deadline extended to 20 March for our @cclguk.bsky.social @biologists.bsky.social-DMM symposium on the developmental origins of paediatric cancers (8 June, @crick.ac.uk)-short talk slots still available. See: www.cclg.org.uk/information-... Please RT!
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
012
Reposted by Anestis Tsakiridis
Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 04/03/2026
Today’s seminar, hosted jointly by DRN and the Cancer Research Seminar Track (CREST) @sheffielduni.bsky.social: Dr Duncan Sproul @sproullab.bsky.social, Institute of Genetics and Cancer, Univ. Edinburgh @edinburghuni.bsky.social Host: Anestis Tsakiridis @tsakiridis.bsky.social All welcome!
011
Anestis Tsakiridis @tsakiridis.bsky.social · 26/02/2026
Final call for everyone interested in the links between developmental biology and childhood cancer: only 2 days remaining to register and submit abstracts for our @cclguk.bsky.social, @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers taking place this June
s.bsky.social
Bluesky
030
Reposted by Anestis Tsakiridis
Matt Towers @matt-towers.bsky.social · 16/02/2026
PDRA position still open in my lab for anyone who wants to solve some outstanding questions in limb development. We have a variety of models and approaches (everything from stem cells to chicks and catsharks). Please share!
057
Reposted by Anestis Tsakiridis
St. Anna Children's Cancer Research Institute (CCRI) @stanna-ccri.bsky.social · 15/02/2026
🎗️#InternationalChildhoodCancerDay! Every year, around 400,000 children worldwide are diagnosed with cancer. Progress is possible: through research, international collaboration and close cooperation between science and clinical care. Read more:🔗 ccri.at/internationa...
ccri.at
International Childhood Cancer Day: Research as the key to better survival rates - St. Anna CCRI
International Childhood Cancer Day: Research as the key to better survival rates (Vienna, February 15, 2026) Every year, around 400,000 children and adolescents worldwide are diagnosed with cancer, wi...
022
Anestis Tsakiridis @tsakiridis.bsky.social · 13/02/2026
2 weeks to go until the registration/abstract submission deadline for our @cclguk.bsky.social @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk this June. Great speaker line up and slots for short talks: www.cclg.org.uk/information-...
cclg.org.uk
Developmental origins of paediatric cancer symposium
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
053
Reposted by Anestis Tsakiridis
Karen J Liu @karenjliu.bsky.social · 06/02/2026
Last couple spots remaining for the Craniofacial GRC in sunny CA! Looks to be a full house, with a great set of up-and-coming #craniofacial biologists spanning evo/devo, genetics, multiomics all the way to stem cells, engineering and repair. @brugmannlab.bsky.social www.grc.org/craniofacial...
grc.org
2026 Craniofacial Morphogenesis and Tissue Regeneration Conference GRC
The 2026 Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration will be held in Ventura, California. Apply today to reserve your spot.
083
Reposted by Anestis Tsakiridis
Rob Fagan @robfagan.bsky.social · 30/01/2026
Appalling news for the biosciences in the UK. I have three grants under review at the moment so the last week since I heard these rumours have been a definite career low point. Shifting priorities (read political interference) are bad enough www.researchprofessionalnews.com/rr-news-uk-r...
researchprofessionalnews.com
MRC instructs grant review boards to slash funding rates - Research Professional News
Boards asked to recommend just three applications for funding, as BBSRC also suspends calls
264
Reposted by Anestis Tsakiridis
Rory Cooper @rorylcooper.bsky.social · 29/01/2026
Check out this postdoc opportunity in a great lab in Sheffield! 🐣🔬
023
Reposted by Anestis Tsakiridis
Ali Twelvetrees @dozenoaks.bsky.social · 28/01/2026
I am completely baffled by the total lack of any action or any evidence of speaking out from our scientific ‘leaders’. We’re in a void of information and the consequences are potentially catastrophic- especially as it looks like BBSRC are following suit.
1146
Anestis Tsakiridis @tsakiridis.bsky.social · 22/01/2026
The lab turned 10 this month, what better way to celebrate than with an amazing cake from @faycooper.bsky.social! I feel lucky to have worked alongside so many talented students, postdocs, and colleagues here in Sheffield over the years.
3241
Reposted by Anestis Tsakiridis
Anahí Binagui-Casas @abinagui.bsky.social · 15/01/2026
🚨DEADLINE TOMORROW FRIDAY 16th JANUARY If you are interested in DevBio, *don't think about it twice* 👇STEPS: 1)Submit an abstract bsdb.org/meetings/ 2)Become a @bsdb.bsky.social member if you aren't already bsdb.org/about-us/#me... 3)Apply for travel grants bsdb.org/membership/#... See you there!
032
Reposted by Anestis Tsakiridis
Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 08/01/2026
rdcu.be/eX8JD DRN new publication alert: Manning et al., 2025, @emmanning.bsky.social, co-led by Marysia Placzek and Elsie Place @elsieplace.bsky.social, in collaboration with Seth Blackshaw @sethblackshaw.bsky.social
rdcu.be
Resolving forebrain developmental organisation by analysis of differential growth patterns
Nature Communications - Experiments on the embryonic chick brain reveal distinct directional growth patterns and a tripartite hypothalamus, challenging the classic segmented prosomere model and...
073
Anestis Tsakiridis @tsakiridis.bsky.social · 15/12/2025
Thank you @stanna-ccri.bsky.social for hosting us, great to see clinicians and groups working on different aspects of neuroblastoma biology coming together and discussing openly about how to build better models that will accelerate the development of new treatments against this devastating disease.
050
Reposted by Anestis Tsakiridis
Vicki Metzis @vmetzis.bsky.social · 09/12/2025
Meeting schedule now online for @bsdb.bsky.social 2026 spring meeting: Molecules to Morphogenesis! ***Abstracts due in by January 16*** Join the outstanding line up! Submit your abstract for a short talk, flash talk, or poster presentation: 👇👇👇 bsdb.org/meetings/
A poster listing the names of invited speakers at the upcoming BSDB 2026 meeting at the University of Warwick, 23-26 March
02415
Reposted by Anestis Tsakiridis
James Briscoe @jamesbriscoe.bsky.social · 03/12/2025
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions: Mentoring Profile raising Leadership training Network building Spread the word... www.biologists.com/grants/devel...
biologists.com
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
07483
Reposted by Anestis Tsakiridis
Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 26/11/2025
Today’s speaker in our DRN external seminar series is Dr Takuya Azami (University of Edinburgh) @tazami.bsky.social Host: Anestis Tsakiridis @tsakiridis.bsky.social All welcome!
0101
Reposted by Anestis Tsakiridis
Chris Toseland @christoseland.bsky.social · 14/11/2025
We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells. www.biorxiv.org/content/10.1... We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.
12210
Reposted by Anestis Tsakiridis
Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 12/11/2025
Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships (IRFs) to join our friendly and collaborative environment, in areas related to developmental biology, stem cells and regenerative biology, and neuroscience.
02823
Reposted by Anestis Tsakiridis
Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 12/11/2025
Today’s speaker in our DRN external seminar series is Professor Jens Januschke (University of Dundee) @dundee.ac.uk Host: Kyra Campbell @kyracampbelllab.bsky.social All welcome!
052
Reposted by Anestis Tsakiridis
Hannah Long @hannahlong.bsky.social · 10/11/2025
📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...
712450
Reposted by Anestis Tsakiridis
Mari Herigstad @herigstad.bsky.social · 06/11/2025
An exciting PhD opportunity to work at the University of Sheffield on how e-cigarettes affect reproduction and offspring: www.findaphd.com/phds/project...
findaphd.com
BBSRC Yorkshire Bioscience DLA Programme: Defining the Reproductive and Offspring Developmental Impacts of e-Cigarettes at University of Sheffield on FindAPhD.com
PhD Project - BBSRC Yorkshire Bioscience DLA Programme: Defining the Reproductive and Offspring Developmental Impacts of e-Cigarettes at University of Sheffield, listed on FindAPhD.com
022
Reposted by Anestis Tsakiridis
Chris Toseland @christoseland.bsky.social · 05/11/2025
Please repost - Multiple PhDs available www.findaphd.com/phds/project... www.findaphd.com/phds/project... www.findaphd.com/phds/project...
13755
Reposted by Anestis Tsakiridis
Rory Cooper @rorylcooper.bsky.social · 03/11/2025
🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪
33618
Reposted by Anestis Tsakiridis
Emma Rawlins @labrawlins.bsky.social · 31/10/2025
Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social
Airway cells in the human lung
0115
Reposted by Anestis Tsakiridis
Stanley E. Strawbridge @stanleystrawbridge.bsky.social · 31/10/2025
🚨 PhD Projects 🚨 We are advertising two UKRI funded PhD projects at the @sheffielduni.bsky.social. #stemcells #development #embryology #reproductivephysiology #mathmaticalmodelling #quantitativebiology
067
Reposted by Anestis Tsakiridis
Giulia Boezio @giulia-boezio.bsky.social · 26/10/2025
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...
biorxiv.org
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
616649
Reposted by Anestis Tsakiridis
Vicki Metzis @vmetzis.bsky.social · 23/10/2025
I am absolutely delighted to share the invited speakers for our upcoming @bsdb.bsky.social "Molecules to Morphogenesis" meeting! Registration and abstract submission is now open - join us! bsdb.org/meetings/ March 23-26, 2026 - UK
16829
Reposted by Anestis Tsakiridis
Conor McCann @conormccann-ens.bsky.social · 20/10/2025
Hot on the heels of our recent basic science preprint. Check out our preprint of a data driven study looking at Hirschsprung Disease Outcomes of children in England using ECHILD (medrxiv.org/cgi/content/...).
medrxiv.org
Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England
Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite lifesaving surgery, can result in increased hospitalisations and a lower quality of life throughout childh...
172