Reposted by Matt Whelan / Mathúin Ó Faoláin
Nature research paper: HIV-1 signalling remodels nuclear pores to licence infection
go.nature.com/49hjtFQ
go.nature.com
HIV-1 signalling remodels nuclear pores to licence infection - Nature
HIV-1 capsid nuclear import at the nuclear pore complex is a bottleneck to resting T cell infection, but HIV-1 overcomes this by triggering receptor-mediated signalling during cell–cell spread to drive nuclear import and licence infection.