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Matt Whelan / Mathúin Ó Faoláin

@mattvxwhelan.bsky.social
731 followers 1.1K following 37 posts

Wellcome Trust Early Career Investigator allied with Jolly and Henriques labs based in QMUL #Cellular #Microbiologist doing #LIVE/#SR #Microscopy of #HIV, #NuclearPores #Tcells and all things #Trafficking and #Host #Cell ?manipulation by #Pathogens!

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Reposted by Matt Whelan / Mathúin Ó Faoláin
Nature @nature.com · 11/05/2026
Nature research paper: HIV-1 signalling remodels nuclear pores to licence infection go.nature.com/49hjtFQ
go.nature.com
HIV-1 signalling remodels nuclear pores to licence infection - Nature
HIV-1 capsid nuclear import at the nuclear pore complex is a bottleneck to resting T cell infection, but HIV-1 overcomes this by triggering receptor-mediated signalling during cell–cell spread to drive nuclear import and licence infection.
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 06/05/2026
Nature Baby! So proud to share below, a story led by myself and the legend @d-mesner.bsky.social + senior-author @jollylab.bsky.social in @nature.com This work excitingly answers many of the key research questions from my @wellcometrust.bsky.social Early Career award! And opens new horizons!
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 20/12/2025
Really excited to be awarded a British council UK-Germany Springboard grant! Exciting times ahead as a UK cohort featuring the labs of myself and Ines Castro and @jollylab.bsky.social will launch trips and research meetings to build a collaboration with @marinalusic.bsky.social in CIID Heidelberg.
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Jean-Yves Tinevez @jytinevez.bsky.social · 15/12/2025
I was invited by @focalplane.bsky.social to write a short description about it: focalplane.biologists.com/2025/12/12/a...
focalplane.biologists.com
A new version of TrackMate with improved integration of key AI algorithms and track edition improvements - FocalPlane
A new version of TrackMate with improved integration of key AI algorithms and track edition improvements -
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 18/11/2025
Really enjoying #EESNucleus day one! Great to be back in @embl.org
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Reposted by Matt Whelan / Mathúin Ó Faoláin
The EMBO Journal @embojournal.org · 18/11/2025
Starting today: @events.embl.org #EESNucleus Make sure to say Hi to our editor @hvodermaier.bsky.social and discuss your latest work with him!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
FocalPlane @focalplane.bsky.social · 18/09/2025
📢 Join us next week for our mini-symposium with the membrane trafficking webinar series Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
focalplane.biologists.com
FocalPlane features... membrane trafficking - FocalPlane
FocalPlane features... membrane trafficking - News
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 08/09/2025
Great to see this in the wild!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Journal of Cell Science @jcellsci.bsky.social · 16/07/2025
Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social. journals.biologists.com/jcs/pages/nu...
Call for papers for JCS Special Issue
Text: Special Issue
Cell Biology of the Nucleus
Guest Editor: Abby Buchwalter
Deadline: 3 November 2025
Image of a cell with a heart-shaped nucleus (Image credit: Hoang Anh Le)
Journal of Cell Science logo
Call for papers
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 24/07/2025
I'll be there!
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 23/07/2025
Really excited to be back in my home away from home, Berlin, for my first conference in Germany: "Life at the Edge: The nuclear envelope in nucleocytoplasmic transport and genome organisation" Really looking forward to it!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Rita Strack @ritastrack.bsky.social · 10/07/2025
Come work at Nature Methods! A dream job. I know from experience 😄
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 10/07/2025
Hyped to be moving to the Blizard Institute @qmul.bsky.social in the Autumn. As part of an exciting new development in infection research within the Blizard, I’ll be a Group Leader, Academic Lead of the Blizard Advanced Light Microscopy (BALM) Facility and soon take up a Senior Lectureship.
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 03/07/2025
Hugely excited to work with this!
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 11/06/2025
This was a lot of fun! Great to be back in my Alma Mater.
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 06/06/2025
Great to see this out! And very fitting the last publication from my PhD is in a @microbiologysociety.org journal. Who played a significant role in supporting my EARLY early career!
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Rita Strack @ritastrack.bsky.social · 29/05/2025
I cannot believe I didn't post about dark sectioning! I can only blame my crazy travel schedule. Check out this amazing tool for background removal in fluorescence microscopy. An important new concept, not 'just another' denoising algorithm.
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 23/05/2025
Really great talk by @melghazaly.bsky.social from @towerslab.bsky.social in #CSH #Retroviruses !
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Jolly Lab @jollylab.bsky.social · 21/05/2025
Yesterday, @mattvxwhelan.bsky.social gave a fantastic talk! Thanks for all the engaging questions and all the great science chat afterwards! #cshretro
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 21/05/2025
It was a huge honour to speak today in the beautiful locale of Cold Spring Harbor, Long Island, NY. At an epic post entry events session on the 50th anniversary of #CSH #Retroviruses
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 20/05/2025
Can't wait for this!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
FocalPlane @focalplane.bsky.social · 16/05/2025
Our latest preprint list is now up on FocalPlane. Our list this week is focusses on research using 🔬microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included. focalplane.biologists.com/2025/05/16/m...
focalplane.biologists.com
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 12/05/2025
Join us at Virtual Virology for an afternoon of excellent science!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Janelia Research Campus @hhmijanelia.bsky.social · 09/05/2025
🖱️ Picking out individual cells in distorted microscopy images is now as easy as clicking a button, thanks to Cellpose3: www.janelia.org/news/newest-...
janelia.org
Newest version of Cellpose can spot cell boundaries even in cloudy conditions
Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Nature Methods @natmethods.nature.com · 17/03/2025
A computational framework links transcriptomic analyses with mechanical signatures to study the interplay between cell mechanical forces and gene expression. www.nature.com/articles/s41...
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Ellenberg Lab @ellenberglab.bsky.social · 19/03/2025
We are #hiring! We have two open postdoc/research scientist positions to join our #ERC funded project MITOFOLD to resolve the organization of mitotic chromosomes! 1) experimental biologist shorturl.at/LjGEM 2) data scientist shorturl.at/nDdhQ Please share! 🙌 We look forward to your application! 🤩
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Austin E. Y. T. Lefebvre @austin-lefebvre.bsky.social · 27/02/2025
Do you LOVE organelles?? Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social! Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy 🧵1/N
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Sketchy News @sketchynews.net · 27/02/2025
[Phys.Org]A completely new type of microscopy based on quantum sensors - Phys.org Researchers at the Technical University of Munich (TUM) have invented an entirely new field of microscopy called nuclear spin microscopy. The team can visualize magnetic signals of nuclear magnetic resonance with a...
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Pablo Carravilla @pablo-carravilla.bsky.social · 19/02/2025
We wrote a protocol to quantify plasma membrane fluidity using a confocal microscope 🔬 Hopefully those interested in measuring membrane biophysical properties in live cells find it useful. We also provide an ImageJ/Fiji tool to make the analysis as easy as possible. www.nature.com/articles/s41...
nature.com
Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols
Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...
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Reposted by Matt Whelan / Mathúin Ó Faoláin
HHMI @hhmi-science.bsky.social · 17/02/2025
Bring your samples into focus! A new version of the #Cellpose cell boundary mapping tool, developed at @hhmijanelia.bsky.social by @computingnature.bsky.social and @marius10p.bsky.social, now works on less-than-perfect microscopy images that are noisy, blurry, or undersampled.
buff.ly
Newest version of Cellpose can spot cell boundaries even in cloudy conditions
Picking out individual cells in distorted microscopy images is now as easy as clicking a button. A new version of Cellpose – the popular tool that maps the boundaries of diverse cells in microscopy
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Reposted by Matt Whelan / Mathúin Ó Faoláin
PLOS Biology @plosbiology.org · 04/02/2025
How is transport directionality achieved through the #trypanosome nuclear pore complex? The current model is symmetrical, but this study reveals that the trypanosome #NuclearPore has an asymmetrical architecture, with conserved hubs that direct mRNA transport 🧪 @plosbiology.org plos.io/3Q36QV2
Expansion microscopy identifies novel asymmetric pore proteins. The images show proExM of cell lines co-expressing epitope-tagged versions of NUP76 (top; magenta), NUP149 (middle; magenta), or NUP140 (bottom; magenta) in combination with NUP110 (green). Images were deconvolved (20 iterations for NUP149 and NUP76; 60 iterations for NUP140) and single planes of the nuclei are shown.
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Matt Whelan / Mathúin Ó Faoláin @mattvxwhelan.bsky.social · 10/01/2025
Time flies... 7 years ago this week. I was a green PhD student off to do a stint in the Suzuki lab at the CZC @hokkaido-univ.bsky.social. Living in Sapporo was like a dream. The excitement for research I witnessed and found in this place was my inspiration to pursue a life in academia!
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Reposted by Matt Whelan / Mathúin Ó Faoláin
dfachinetti.bsky.social @dfachinetti.bsky.social · 08/01/2025
#1 Happy to share our last work published in @NatureCellBio about a new cell cycle checkpoint that senses nuclear shape & mechanics to guarantee genome integrity www.nature.com/articles/s41.... Great work from @sol-herve.bsky.social & Andrea Scelfo in close collaboration with @katemiro.bsky.social
nature.com
Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint - Nature Cell Biology
Hervé, Scelfo et al. show that chromosome mis-segregation induces mTORC2- and ATR-mediated p53 activation through a mechanosensitive checkpoint at the nuclear envelope triggered by altered heterochrom...
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Onisillos @onisillos.bsky.social · 17/12/2024
"Given the exodus of the academic community from X to Bluesky, we would advocate that publishers and database managers incorporate direct-share links to Bluesky, and so assist the academic community in its shift to a platform more suited to scientific discussion." www.nature.com/articles/d41...
nature.com
Facilitate the move of academia from X to Bluesky
Letter to the Editor
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Brian Northan @truenorth-ia.bsky.social · 16/12/2024
I finally got around to making a video about my utilities to render 3D projections in Jupyter notebooks. The code is useful but a bit rough so I also suggest taking a look at @guiwitz.bsky.social microfilm and @haesleinhuepf.bsky.social stackview as more polished options. youtu.be/9yOA8R03trE
youtu.be
Jupyter Notebook 3D Projections
YouTube video by Brian Northan
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Reposted by Matt Whelan / Mathúin Ó Faoláin
FocalPlane @focalplane.bsky.social · 16/12/2024
📢Now up on FocalPlane: Probes 101 – How to choose a fluorescent probe for your imaging experiment. Lina El Hajji talks us through the optimal photophysical properties & weighs up the pros & cons of FPs versus small molecule dyes & the options in between! focalplane.biologists.com/2024/12/14/p...
focalplane.biologists.com
Probes 101 – How to choose a fluorescent probe for your imaging experiment - FocalPlane
Probes 101 – How to choose a fluorescent probe for your imaging experiment - Tools
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Joachim Goedhart @joachimgoedhart.bsky.social · 16/12/2024
There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Dutchscientist (the real one) @dutchscientist.bsky.social · 11/12/2024
jobs.surrey.ac.uk/Vacancy.aspx... At the University of Surrey, we are looking for a new colleague. Join us as Lecturer/Senior Lecturer in Immunity and Infection Biology at the School of Veterinary Medicine. Do get in touch for any queries or forward to your networks 🙂 #MicroSky #IDSky #MicrobiomeSky
jobs.surrey.ac.uk
Jobs at the University of Surrey
[No Meta Tag Description provided]
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Reposted by Matt Whelan / Mathúin Ó Faoláin
Nicky O’Boyle @oboylelab.bsky.social · 02/12/2024
We're looking for an Assitant Professor in Microbiology to join us @tcdgenmicro! Come and join our growing team. www.tcd.ie/microbiology... www.tcd.ie/hr/vacancies/ Job ID: 037876. Closes 31st January
tcd.ie
Research Groups - Microbiology | Trinity College DublinmenusearchSearchmenu
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Reposted by Matt Whelan / Mathúin Ó Faoláin
David Gaboriau @dgaboriau.bsky.social · 01/12/2024
Useful orders of magnitude
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Birds Are Dinosaurs @birdsaredinosaurs.bsky.social · 29/11/2024
Dune has the same plot as the Westminster Dog Show: After generations of careful breeding, we have produced this perfect little freak of nature and now it has behavioral issues
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Reposted by Matt Whelan / Mathúin Ó Faoláin
BioImaging North America @bioimagingna.bsky.social · 25/11/2024
Happy #MicroscopyMonday! The recordings of the #Virtual #I2K2024 workshops are available now tinyurl.com/VirtualI2K20... Thanks to all who presented! Please re-share! 2022 and 2023 content available too: www.youtube.com/@I2KConference
Virtual I2K Flyer notifying that the Recordings are available on the I2K YouTube channel: https://www.youtube.com/@I2KConference
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Helen Zenner @helenzsci.bsky.social · 13/11/2024
One of my favourite things to do at FocalPlane is hosting webinars (well, not so much the speaking on screen…). I’ve met some fantastic scientists & getting email saying they'll speak is so exciting! You can check out the recordings of our webinars here: focalplane.biologists.com/focalplane-f...
focalplane.biologists.com
FocalPlane features...
FocalPlane
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