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Hartmut Vodermaier

@hvodermaier.bsky.social
665 followers 609 following 49 posts

Senior Scientific Editor for @embojournal.bsky.social @embopress.org Ubiquitin & other PTMs, cell cycle & cell division, 3R stuff (replication, recombination, repair). Opinions my own. He/his.

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Hartmut Vodermaier @hvodermaier.bsky.social · 01/07/2026
a plant SUMO E3 that looks like a STUbL - this was quite a surprise...
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The EMBO Journal @embojournal.org · 30/05/2026
The end of a great meeting: #EMBOevents #EMBOtelomere Our editor @hvodermaier.bsky.social presents the @embojournal.org poster prize to winner Valeria Rubeo from @crcm.bsky.social - congratulations! meetings.embo.org/event/26-tel...
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Hartmut Vodermaier @hvodermaier.bsky.social · 10/04/2026
Beautiful cover this time - makes me miss the days when they were still produced to adorn real print issues in all their glory!
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Vladimir Volkov 🇺🇦 @vladimirvolkov.bsky.social · 20/03/2026
Happy to see the first paper from the lab published in the EMBO J today: link.springer.com/article/10.1... In it, we reconstitute self-assembling cooperative oligomers of human Ndc80 and Ska kinetochore complexes that stabilise microtubule ends, and study these samples using cryoET and TIRF
link.springer.com
Microtubule end stabilisation by cooperative oligomers of Ska and Ndc80 complexes - The EMBO Journal
During mitosis, properly aligned chromosomes stabilise microtubule ends with the help of kinetochores to ensure timely segregation of chromosomes. Microtubule-binding components of the human outer kin...
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Hartmut Vodermaier @hvodermaier.bsky.social · 20/02/2026
Only three more days, excited to meet the ubiquitin crowd again at #KSUbiquitin26 @keystonesymposia.bsky.social hubs.la/Q03TCqzV0
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The EMBO Journal @embojournal.org · 28/01/2026
See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers! link.springer.com/article/10.1...
link.springer.com
Mitotic entry: Bora takes Polo to Aurora, and gives them a hug - The EMBO Journal
The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...
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Hartmut Vodermaier @hvodermaier.bsky.social · 12/12/2025
Cannot help but feeling the Impact Factor hype may have gone awry by now...?
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Anna Abalkina @abalkina.bsky.social · 02/12/2025
Happy Advent! !!!🎄✨ Day 2. Today's puzzle is about paper mills' red flags! Do you spot the problem? papermills.tilda.ws/advent2025
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Hartmut Vodermaier @hvodermaier.bsky.social · 21/11/2025
My seminar will only be on Nov 26th though - so still a chance to catch it 😀
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Hartmut Vodermaier @hvodermaier.bsky.social · 21/11/2025
Looking forward to my upcoming site visit in Madrid!
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Hartmut Vodermaier @hvodermaier.bsky.social · 17/11/2025
As my conference year draws to a close: still one last highlight coming up #EESNucleus on home turf @events.embl.org!
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Hartmut Vodermaier @hvodermaier.bsky.social · 03/11/2025
It's been an amazing year for the new PTM field of #MARUbylation - happy that I could get involved first-hand!
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Hartmut Vodermaier @hvodermaier.bsky.social · 21/09/2025
On the train to Montpellier for the #EMBOsumoylation conference - looking forward to the 2nd recurrence of this #EMBOevents workshop and to the latest research in the SUMO field! meetings.embo.org/event/25-sum...
meetings.embo.org
SUMOylation: From discovery to translation
Sumoylation is an essential post-translational modification that regulates thousands of target proteins in a dynamic manner. Small ubiquitin-like modifiers (SUMOs) can be attached to target proteins …
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Hartmut Vodermaier @hvodermaier.bsky.social · 04/09/2025
I continue to be astounded by the recent resurgence of intriguing studies revolving around #PARPs and the interplay of ADP-ribosylation with other PTMs! Latest example that we published in @embojournal.org:
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Hartmut Vodermaier @hvodermaier.bsky.social · 02/09/2025
Was fun to work on this manuscript - never would have thought that an E1 enzyme could be involved in selecting a particular #ubiquitin -like protein isoform over another!
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The EMBO Journal @embojournal.org · 02/09/2025
Our RNA & translation editor Cornelius Schneider is excited to be at #EMBLProtein starting tomorrow – make sure to say Hi to him and drag him to your posters 😀 @events.embl.org ‬
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Hartmut Vodermaier @hvodermaier.bsky.social · 16/07/2025
Fascinating new insights into evolutionary conservation/diversification/repurposing in the chromosome segregation machinery!
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Hartmut Vodermaier @hvodermaier.bsky.social · 10/06/2025
Another week, another great conference - happy to be at #EESAgeing on home turf
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NPR @npr.org · 05/06/2025
Senate Democrats warn Trump plan to wipe out public broadcasting funding will shut down stations, eliminate essential services. But House GOP scheduled to vote to clawback $1.1 billion next week.
n.pr
Partisan battle lines form over Trump's plan to defund NPR & PBS
Senate Democrats warn Trump plan to wipe out public broadcasting funding will shut down stations, eliminate essential services. But House GOP scheduled to vote to clawback $1.1 billion next week.
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Cahir O'Kane @cahirokane.bsky.social · 05/06/2025
This vital resource @flybase.bsky.social is in acute peril: its funding blocked by the vindictiveness of Trump. Emergency funds needed *now*, pending longer term solutions. Personal donations from Europe can be made here (UK taxpayers can gift-aid); other routes also possible. US appeal to follow.
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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The EMBO Journal @embojournal.org · 05/06/2025
A scary situation!
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Retraction Watch @retractionwatch.com · 04/06/2025
‘Anyone can do this’: Sleuths publish a toolkit for post-publication review @averyorrall.bsky.social reports on an initiative from @reeserichardson.bsky.social and colleagues
retractionwatch.com
‘Anyone can do this’: Sleuths publish a toolkit for post-publication review
For years, sleuths – whose names our readers are likely familiar with – have been diligently flagging issues with the scientific literature. More than a dozen of these specialists have teamed up to cr...
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Román González-Prieto @romangp.bsky.social · 04/06/2025
If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!
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Netherlands Cancer Institute @nkinl.bsky.social · 05/06/2025
Today, these amazing NKI researchers are pushing their limits by climbing the Alpe d’Huez. Go for it lovely people! We are proud to see so many of you dedicate your time and effort to supporting cancer research. With @oncodeinstitute.bsky.social #AlpedHuZes #cancerresearch #ad6 #NKI
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Hartmut Vodermaier @hvodermaier.bsky.social · 04/06/2025
Grateful for the opportunity to meet with so many enthusiastic early-career scientists and sharing behind-the-scenes insights with them #wUeBI2025
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Hartmut Vodermaier @hvodermaier.bsky.social · 02/06/2025
Excited that the symposium #wUeBI2025 @grk2243.bsky.social is now about to start - looking forward to exciting news from the #ubiquitin field, and to meeting this great community again!
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Hartmut Vodermaier @hvodermaier.bsky.social · 19/05/2025
Ever wondered how it would be as an Editor? Here's your chance to try as an absence cover with our wonderful colleagues from @emboreports.org!
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Randall Munroe @xkcd.com · 08/04/2025
Tariffs xkcd.com/3073
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Randall Munroe @xkcd.com · 17/03/2025
Lungfish xkcd.com/3064
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Hartmut Vodermaier @hvodermaier.bsky.social · 08/04/2025
Great to get to publish another one on the emerging connections between ADP-ribosylation, immune signaling, ubiquitin and protein aggregation/degradation
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Iannacone Lab @iannaconelab.bsky.social · 01/04/2025
💡Exciting news! Our latest study, in collaboration with Prof. Mirela Kuka’s lab, is out now—uncovering how T cell–derived IFN-γ can suppress T follicular helper (TFH) cells and limit antibody responses. 🚀🧵(1/10) www.embopress.org/doi/full/10....
embopress.org
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses | The EMBO Journal
imageimageSubcutaneous infection by lymphocytic choriomeningitis virus (LCMV) is characterized by skewed CD4+ T-cell polarization, as well as severely impaired differentiation of T follicular helper (...
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The EMBO Journal @embojournal.org · 01/04/2025
Highlighted in Issue 7: Lysosome-CDK4/6 co-targeting in cancer therapy Algal spliceosome structure Also: Opposite synaptic plasticity effects of Ras isoforms Novel biosensor for spatiotemporal dynamics of STING activation Cover: @plenart.bsky.social and coworkers www.embopress.org/toc/14602075...
This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto cells treated with the PLK1 inhibitor BI2536 spend prolonged periods of time in a prophase-like state with condensed chromosomes. Cells stained with 5-SiR-Hoechst imaged on a spinning disk confocal microscope.

Scientific image by Monica Gobran
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Maria Polychronidou @mpolychronidou.bsky.social · 28/03/2025
From large language models (LLMs) to large reasoning models (LRMs) based on chain-of-thought. Are LRMs "“genuinely reasoning” or “merely mimicking” the kinds of human reasoning that is in the pretraining or post-training data"? Interesting read ➡️ www.science.org/doi/10.1126/...
science.org
Artificial intelligence learns to reason
Julia has two sisters and one brother. How many sisters does her brother Martin have?Solving this tiny puzzle requires a bit of thinking. You might mentally picture the family of three girls and one b...
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Hartmut Vodermaier @hvodermaier.bsky.social · 27/03/2025
Not to over-rate journal rankings - but this is nevertheless surely good news!
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The EMBO Journal @embojournal.org · 17/03/2025
Lu Gan (甘露) and collaborators use cryo-electron tomography to reveal the nanoscale architecture of human #chromatin in situ: G1 and metaphase chromatin is devoid of mega-complexes beyond dinucleosome regularities www.embopress.org/doi/full/10....
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The EMBO Journal @embojournal.org · 17/03/2025
In issue 6: Commentary: organoids for decoding host-microbe interactions Importance of mitochondrial DNA elimination during spermatogenesis How kinesin KIF12 promotes steatohepatitis Cancer cell adaptation strategies to aneuploidy Cover: Daniel Ott, Anne Spang et al www.embopress.org/toc/14602075...
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The EMBO Journal @embojournal.org · 12/03/2025
Medicine & Society: The human condition A virtual seminar series coorganized by @embopress.org - feel free to subscribe & attend! cancerprev.com/medicine-soc...
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The EMBO Journal @embojournal.org · 03/03/2025
In issue 5: Review: Arginine in the center of cellular nitrogen metabolism Elongator polymerizes polyglutamylated tubulin Shu complex HR factor to the replication fork! Ephrin as EGFR ligand promotes gastric cancer metastasis Cover by Ito, Hata, Kitagawa et al www.embopress.org/toc/14602075...
This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole cycle as marked by acetylated tubulin. Daughter centrioles form on mother centrioles (yellow) and undergo stepwise engagement (blue, green, red) before disengaging (purple) to become new mother centrioles.

Scientific image by the authors
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Björn Schumacher @bjornschumacher.bsky.social · 02/03/2025
Register and submit your abstract now: The ageing genome: from mechanisms to disease www.embl.org/about/info/c...
embl.org
The ageing genome: from mechanisms to disease
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Hartmut Vodermaier @hvodermaier.bsky.social · 27/02/2025
don't tell our @embojournal.org RNA editor...
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Anja Groth @groth-anja.bsky.social · 26/02/2025
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.   Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...
embl.org
DNA replication and genome maintenance: from basic biology to disease
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Hartmut Vodermaier @hvodermaier.bsky.social · 26/02/2025
Happy that I got to handle and help publish this cool new work for @embojournal.org And after many years of PARPi/(poly-ADP)ribose craze, exciting to see mono-ADP-ribosylation starting to reveal its secrets in so many ways now!
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Hartmut Vodermaier @hvodermaier.bsky.social · 19/02/2025
#Chlamydomonas on our latest @embojournal.org cover - nice flash-back to my Diploma work in this organism many many years ago 😯
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The EMBO Journal @embojournal.org · 08/01/2025
Happy New Year with our first 2025 issue! With cover by Thomas Laux, Ning Zhang et al and: FNDC1 as myokine Tubulin glutamylation in axon guidance Chromatin remodelers aiding meiotic recombination Maintaining subunit essentiality during RUBISCO evolution www.embopress.org/toc/14602075...
This cover highlights the article Deciphering the molecular logic of WOX5 function in the root stem cell organizer by Ning Zhang, Pamela Bitterli, Thomas Laux and colleagues. The image highlights the expression (green color) of WOX5 in the root stem cell organizer, the quiescent center.

Scientific image by the authors
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Hartmut Vodermaier @hvodermaier.bsky.social · 24/12/2024
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #Books #BookSky #BookChallenge Day 20 – finishing with the most recent addition...
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Hartmut Vodermaier @hvodermaier.bsky.social · 23/12/2024
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #Books #BookSky #BookChallenge Day 19
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Hartmut Vodermaier @hvodermaier.bsky.social · 22/12/2024
Choose 20 books that have stayed with you or influenced you. One book per day for 20 days, in no particular order. No explanations, no reviews, just covers. #Books #BookSky #BookChallenge Day 18
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Hartmut Vodermaier @hvodermaier.bsky.social · 21/12/2024
#Books #BookSky #BookChallenge Day 17
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Hartmut Vodermaier @hvodermaier.bsky.social · 20/12/2024
#Books #BookSky #BookChallenge Day 16
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Hartmut Vodermaier @hvodermaier.bsky.social · 19/12/2024
#Books #BookSky #BookChallenge Day 15: indeed "...deserves to sell more copies than the Bible" ☺️
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