Cook et al. show that macrophages sense cell volume disruption as a danger signal promoting transcriptional reprogramming and inflammatory responses via ty

The bacterial ubiquitin ligase NleL evades host defence mechanisms both by inhibiting pyroptosis and by preventing infected intestinal epithelial cells from being extruded into the lumen and expelled ...

Raffaele Vitolo (Adi) spiega a Open perché i dottorandi considerano «incompatibile» con le direttive Ue l’emendamento Occhiuto alla legge Pnrr, che introduce due nuovi contratti

🥇2025 ACDS Professional Development Award 🥇 Applications are now open! Are you a PhD student or early-career researcher in the cell death field? Don’t miss your chance to apply for our $2,000 travel ...

Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate dendritic cells.

ACE2 in macrophages promotes infection that enables an intrinsic antiviral response to SARS-CoV-2.

Nature Immunology - Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate...