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García Knight Lab

@levelab.bsky.social
139 followers 294 following 6 posts

Laboratorio de Enfermedades Virales Emergentes. Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México

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Reposted by García Knight Lab
bioRxiv Genomics @biorxiv-genomic.bsky.social · 11h
Phylodynamic analysis reveals asymmetric and accelerating global spread of dengue virus www.biorxiv.org/content/10.64898/20…
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PLOS @plos.org · 22h
Interested in contributing to research in your field, supporting rigorous peer review, and building on your research experience? Several of our journals are currently recruiting Academic Editors 🤝 🔗 Find out more and explore what the role involves: plos.io/4z3Uq3o
Recruitment banner: PLOS seeking Academic Editors — "Become an Academic Editor" — currently recruiting for PLOS One, PLOS Global Public Health, PLOS Computational Biology, PLOS Digital Health, PLOS Pathogens and PLOS Genetics; PLOS logo left and a black-and-white butterfly with colorful swooshes on
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Viruses MDPI @virusesmdpi.bsky.social · 29/09/2026
🧠 New in Viruses — a Highly Accessed review: #Nipah Virus: A Neurotropic #Zoonosis From molecular biology to neuropathogenesis, clinical manifestations, and translational advances — covering how NiV invades the CNS and current vaccine/therapeutic efforts. 🔗 www.mdpi.com/1999-4915/18...
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Pathogen Dynamics Unit @pducambridge.bsky.social · 25/09/2026
We have an open Assistant/Associate Professor position in Pathogen Genetics - come and join our department! 🦠 🧫 🧬https://www.cam.ac.uk/jobs/assistantassociate-professor-in-pathogen-genetics-pc51175
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Steve Russell @steverus.bsky.social · 24/09/2026
We’re recruiting to an assistant/associate professorship in Pathogen Genetics- come and join us. www.cam.ac.uk/jobs/assista...
cam.ac.uk
Assistant/Associate Professor in Pathogen Genetics
Applications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu...
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Centre for Tropical Medicine and Global Health @tropicalmedicine.ox.ac.uk · 23/09/2026
#ResearchHighlight from Charles Agoti @kemriwellcome.bsky.social Genomic epidemiology of coxsackievirus A24 variant during the 2024 acute hemorrhagic #conjunctivitis outbreak in Coastal Kenya Read more 👉 ndm.ac/tropmed-res-hi Full publication 👉 journals.plos.org/plospathogen...
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Gytis Dudas @evogytis.bsky.social · 23/09/2026
And here is the preprint, available online on Baltic Unity Day (Sep 22). Happy citing! www.biorxiv.org/content/10.6... Thanks again to @barney-potter.bsky.social, @gkarthik.com, @sidneymbell.bsky.social, and @mftorresj.bsky.social
biorxiv.org
baltic: the Backronymed Adaptable Lightweight Tree vIsualisation Code
For ten years, baltic (Backronymed Adaptable Lightweight Tree vIsualization Code) has been used to make annotated phylogeny figures in molecular epidemiology, including during the West African Ebola e...
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Reposted by García Knight Lab
Pathoplexus @pathoplexus.org · 22/09/2026
1/ 🧬 A big #Pathoplexus milestone: you can now optionally include raw sequencing reads alongside your consensus sequences! Hosting raw reads alongside consensus data helps improve reproducibility & allow in-depth analyses. 📰 Read more: pathoplexus.org/news/2026-09...
AI-generated image showing raw reads (short reads) lining up above a consensus sequence, with both the raw reads and consensus sequence labelled. Vague images below show a virus, coverage, and DNA.
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The Lancet Microbe @lancetmicrobe.bsky.social · 16/09/2026
New research article Evaluation of the effect of serotype on pneumococcal conjugate #vaccine induced immunity: an exploratory analysis of the PREVENTING PNEUMO 2 trial www.thelancet.com/journals/lan... #IDSky #ClinMicro #MicroSky #Streptococcus #OpenAccess #OA
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Nature Portfolio @natureportfolio.nature.com · 12/09/2026
Primary infection of varicella zoster virus causes chickenpox, and reactivation later in life can cause shingles and other complications. A Primer in Nature Reviews Disease Primers describes the epidemiology, diagnosis and management of varicella zoster virus infection. go.nature.com/4dxTgF5 🧪
This is figure 1, which shows varicella zoster virus life cycle.
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Arbovirus seminars @arbovirus.bsky.social · 11/09/2026
Come join us for the first seminar of the series - some fascinating work by Zhouming Liu on La Crosse Virus infection. All welcome - just email us for a Zoom link.
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Science Magazine @science.org · 09/09/2026
Detecting viruses in whole blood usually requires a complex process that prevents swift, point-of-care detection in low-resource settings. Now, new #ScienceAdvances research finds Zika and hepatitis C virus can be detected in dried whole blood by direct RNA amplification. scim.ag/4zTNcAq
scim.ag
Amplification of RNA for identification of Zika and HCV in whole blood
Direct RNA amplification from whole blood is fundamentally limited by rapid enzymatic degradation and inhibitory matrix effects. Here, we present a blood drying protocol that enables sensitive and rob...
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Giles Wilkes @gilesyb.bsky.social · 09/09/2026
It's always the way, isn't it giftarticle.ft.com/giftarticle/...
Graph shows far right support higher where the number of foreign nationals is lowest
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Viruses MDPI @virusesmdpi.bsky.social · 07/09/2026
🍅 Particular interest in Viruses: #CIDER‑Seq reveals a New World #begomovirus–alphasatellite complex associated with #tomato leaf curl disease in Morelos, Mexico, with mixed infections of ToGMoV, ToSLCV, ToChLPV and tomato‑associated alphasatellites. 👉Read more: www.mdpi.com/1999-4915/18...
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Carolina Lucas @carolilucas.bsky.social · 04/09/2026
Dengue vaccines face a uniquely difficult challenge: protecting against four distinct viral serotypes at once. 🦟 Our new study in JEM: rupress.org/jem/article/... A 🧵 on why tetravalent vaccine design does not necessarily mean tetravalent immunity.
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Heather Ferguson @drheatherferg.bsky.social · 03/09/2026
🚨Breaking news UKHSA finds invasive Aedes aegypti breeding in east London, prompting enhanced surveillance. ⬇️ Invasive mosquito species detected in east London - GOV.UK www.gov.uk/government/n...
gov.uk
Invasive mosquito species detected in east London
UKHSA finds invasive Aedes aegypti breeding in east London, prompting enhanced surveillance.
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Daniel Ríos @yosoyden.bsky.social · 03/09/2026
We’re kicking off the 14th meeting of the Mexican Society for Developmental Biology! Looking forward to learning from so many invited speakers from many fields and models from the #devbio world
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Waggoner Lab @labwaggoner.bsky.social · 27/08/2026
Bats’ remarkable longevity and immunity are linked through pleiotropic adaptations to viruses and ageing-related disease @nature.com @psudmant.bsky.social @ucberkeleyofficial.bsky.social @lucievirevolte.bsky.social www.nature.com/articles/s41...
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Jonathan Howard @joho.bsky.social · 27/08/2026
nbcnews.com
Infant in Pennsylvania is one of two people reported to die of measles this week
The deaths were the first associated with measles in the state in 35 years.
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Zoonotic Diseases MDPI @zoonoticdis.bsky.social · 26/08/2026
Review published this August!📚 by Adedeji et al.: "Five Decades of Mpox in West Africa: History, Epidemiology, Viral Evolution, and Reservoir Ecology (1970–2025)"🌍🧬 📄Pages: 15 🔗Link: www.mdpi.com/4031370 #Mpox #Zoonoses #Epidemiology #Virus #Virology #Africa #OpenAccess
Spatial and Taxonomic Distribution of Monkeypox (MPXV) and Orthopoxvirus (OPXV) Antigen Detection in West African Mammalian Wildlife. Blue: MPXV/OPXV Antibodies Detected (+), orange: OPXV DNA Detected (+), green: MPXV DNA Detected (+).
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Microbes.Info @microbesinfo.bsky.social · 26/08/2026
👍
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Journal of Virology @jvico-eics.bsky.social · 24/08/2026
If you're an early-career virologist and are interested in publishing with JVI, apply now to our New Voices in Virology initiative! Deadline is Sept. 1. journals.asm.org/journal/jvi/...
New Voices in Virology with QR code to application details
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Kristian G. Andersen @kgandersen.bsky.social · 24/08/2026
We have a (dry lab) Postdoc Position in Viral Genomics & Pathogen Surveillance here in wonderful and sunny San Diego 🏄‍♂️☀️! We're looking to continue to build our AI and broader infectious disease surveillance efforts, with a focus on our outbreak.info platform. Read more: andersen-lab.com/about/
andersen-lab.com
About | Andersen Lab
Learn more about the Andersen Lab, as well as jobs and career opportunities.
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BK. Titanji @boghuma.bsky.social · 21/08/2026
MMWR on Mpox surveillance in the US shows continuous local circulation during the last three years which suggests that it is transitioning towards endemic circulation in the United States www.cdc.gov/mmwr/volumes...
cdc.gov
Monkeypox Virus Surveillance
This report describes cases of monkeypox virus infection reported during 2024–2025.
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Mauricio Comas-Garcia @m-comas-phys-virol.bsky.social · 20/08/2026
Ciencia en el bar. Me han invitado a hablar de virus y ciencia en un bar. Qué maravilla.
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Parasites Without Borders @pwbglobal.bsky.social · 20/08/2026
Have you spent time getting to know our Tropical Medicine Curriculum yet? It’s a self-study resource in parasitic and other tropical diseases. Learn more at parasiteswithoutborders.com/all-courses
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Scholars at Risk @scholarsatrisk.bsky.social · 19/08/2026
Is your university interested in joining our network to help promote #AcademicFreedom? Consider hosting this at-risk scholar within your #Microbiology department! www.scholarsatrisk.org/actions/host…
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Philip Bejon @philipbejon.bsky.social · 18/08/2026
Kilifi is a coastal County in Kenya, where @kemriwellcome.bsky.social has undertaken 35 years sentinel surveillance of malaria. Dramatic changes that I think aren't widely appreciated. Work led by @alice-kamau.bsky.social Highlights and link to paper:
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Vasilakis Lab @vasilakislab.bsky.social · 18/08/2026
We look forward welcoming you to our webinar on Sept. 8. Dr Marrazzo, CEO of IDSA will be presenting "Emerging Infection Research in 2026: Opportunities and Threats". Register: www.zoomgov.com/webinar/regi... @astmh.bsky.social @utmbhealth.bsky.social @amersocvirology.bsky.social
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The Lancet Microbe @lancetmicrobe.bsky.social · 18/08/2026
New research article A WHO International Standard for neutralising antibodies to #Chikungunya virus: development and evaluation www.thelancet.com/journals/lan... #IDSky #ClinMicro #ViroSky #CHIKV #OpenAccess #OA
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Carl Zimmer @carlzimmer.com · 12/08/2026
A new study suggests that the current Bundibugyo epidemic is a new spillover from an animal host--not a resurgence of human cases from the two previous human outbreaks. www.nature.com/articles/s41...
nature.com
Emergence of a Bundibugyo virus variant in the 2026 outbreak in the Democratic Republic of the Congo and Uganda - Nature Medicine
A phylogenetic analysis of 22 genomes from the recent Bundibugyo virus outbreak in the Democratic Republic of the Congo and Uganda suggests the outbreak was caused by a new zoonotic spillover event.
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Vasilakis Lab @vasilakislab.bsky.social · 12/08/2026
We are delighted to announce the roster of speakers for our 7th year of “Virtual Seminar Series on Vector-Borne and Zoonotic Diseases”. Details of the upcoming seminar will be coming shortly. @utmbhealth.bsky.social @astmh.bsky.social @amersocvirology.bsky.social @sbvirologia.bsky.social
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Sur Herrera Paredes @surh.bsky.social · 03/08/2026
Check out our new preprint on "Rich mobilomes and a conserved adaptive core in bacteria from an intensifying Mexican soda lake" www.biorxiv.org/content/10.6... We isolate and sequence bacteria from a crater lake and find many mobile genetic elements! @liigh-unam.bsky.social
biorxiv.org
Rich mobilomes and a conserved adaptive core in bacteria from an intensifying Mexican soda lake
The haloalkaline maar lake at Rincón de Parangueo, in central Mexico’s volcanic belt, is a doubly extreme habitat where high salinity and high alkalinity co-occur. Unlike the long-lived soda lakes tha...
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The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 03/08/2026
New Review A review of Bundibugyo virus and the 2026 outbreak: lessons for epidemic preparedness www.thelancet.com/journals/lan...
thelancet.com
A review of Bundibugyo virus and the 2026 outbreak: lessons for epidemic preparedness
The ongoing 2026 outbreak of Ebola virus disease caused by Bundibugyo virus (BDBV) in the Democratic Republic of the Congo and Uganda has renewed attention to one of the least studied human-pathogenic...
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Amy Maxmen, PhD @amymaxmen.bsky.social · 30/07/2026
The US owes the Pan-American Health Organization $135 million in past dues. Trump's budget proposal cuts funding for PAHO entirely, even though our contribution is 0.001% of federal spending. The result will be even weaker defenses agst measles, dengue & more. www.nytimes.com/2026/07/30/h...
nytimes.com
Former Officials Protest U.S. Plan to Defund Pan American Health Organization
The group of former health and national security officials warned that Americans will be more vulnerable to infectious disease threats.
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Science Magazine @science.org · 30/07/2026
Research on the fossil record of mammals in Mexico suggests that the geographic region acted as a biodiversity “holding pen” for 10 million years. Learn more this week in Science: scim.ag/4xhNmQ9
A three-dimensional rendering shows the land bridge connection between North and South America. Research on the fossil record of mammals in Mexico suggests that the geographic region acted as a biodiversity “holding pen” for 10 million years, buffering the pace of both northward and southward movements of mammal species leading up to the Great American Biotic Interchange.

Illustration: C. Bickel and V. Penney/Science. Data: NASA Blue Marble Imagery, August 2026; B. Tozer, D. T. Sandwell, W. H. F. Smith, C. Olson, J. R. Beale, P. Wessel, Global bathymetry and topography at 15 arc sec: SRTM15+ (2019), distributed by OpenTopography, https://doi.org/10.5069/G92R3PT9, accessed 24 June 2026
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Eric Topol @erictopol.bsky.social · 30/07/2026
Killer T cells (CD8+) in Long Covid directed to SARS-CoV-2 and Herpes virus antigens are persistent and may have a causal role www.cell.com/cell-reports...
cell.com
Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID
Ma et al. perform deep-phenotyping of CD8+ T cells specific for viruses implicated in LC pathogenesis: SARS-CoV-2, CMV, and EBV. These T cells from LC individuals share features of terminal differenti...
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Mauricio Comas-Garcia @m-comas-phys-virol.bsky.social · 27/07/2026
We are excited to share our first paper on alphavirus core #evolution link.springer.com/article/10.1...
link.springer.com
Highly Conserved Core Residues Define Old-World Alphaviruses and Trace Early Evolutionary Divergence - Journal of Molecular Evolution
Alphaviruses are positive-sense, single-stranded RNA viruses that assemble into striking double-icosahedral particles. During budding, the nucleocapsid core forms in the cytoplasm and adopts a T = 4 i...
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Michael Emerman @memerman.bsky.social · 27/07/2026
My very last, last author paper now published a year since retirement. All credit to grad Caroline Langley who did brilliant work, super tech Michelle Lily who finished the experimental work after Caroline graduated, and my ever wise collaborator (and Caroline’s co-mentor) @harmitmalik.bsky.social
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García Knight Lab @levelab.bsky.social · 24/07/2026
Travel associated case of ECSA CHIKV highlights the potential for emerging outbreaks of this previously unreported lineage in Mexico. Detection and genomic characterization of a travel-associated ECSA lineage chikungunya virus infection in Mexico | ASM Case Reports journals.asm.org/doi/10.1128/...
journals.asm.org
Detection and genomic characterization of a travel-associated ECSA lineage chikungunya virus infection in Mexico | ASM Case Reports
Chikungunya (CHIKV; genus Alphavirus, family Togaviridae) is a re-emerging Aedes-borne virus that causes an acute febrile illness (CHIKF) with an incubation period of typically 3–7 days. The disease i...
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García Knight Lab @levelab.bsky.social · 23/07/2026
Our first LEVE lab review! Vector competence across Aedes aegypti populations shaped by host-preference adaptation and host-pathogen interactions | Journal of Virology journals.asm.org/doi/10.1128/...
journals.asm.org
Vector competence across Aedes aegypti populations shaped by host-preference adaptation and host-pathogen interactions | Journal of Virology
Mosquitoes are vectors for numerous arthropod-borne viruses (arboviruses) that are a huge global health burden. Chief among the vectors that transmit arboviruses is Aedes aegypti, the yellow fever mosquito, which transmits not only yellow fever virus (YFV) but also dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) viruses. Together, these pathogens are the most prevalent arboviruses worldwide, driving recurrent epidemics, with DENV alone being responsible for ~100 million annual clinical cases and ~30,000 deaths (1, 2). In addition to these pathogens, Ae. aegypti can also function as a secondary vector for understudied arboviruses, including Mayaro, Bunyamwera, and Cache Valley viruses (3–6). The expanding global distribution of Ae. aegypti, coupled with its capacity to sustain infections with arboviruses from multiple viral taxa—e.g., Flaviviridae, Togaviridae, and Bunyavirales—poses a significant risk for viral emergence and disease transmission.
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Loukas Theodosiou @bioinformatician.bsky.social · 19/07/2026
After four years, several updates and a handful of CRAN releases, 𝗹𝘁𝗰 𝗰𝗼𝗹𝗼𝗿 𝗽𝗮𝗹𝗲𝘁𝘁𝗲 𝗥-𝗽𝗮𝗰𝗸𝗮𝗴𝗲, reached a version I feel genuinely good about sharing with the community. github.com/loukesio/ltc...
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Thiago Carvalho @cyrilpedia.bsky.social · 26/05/2026
'We find that the Ty3-like giant transposon Burro1 is an ancient element that retains its mobility. Burro1 has incorporated a host-derived anti-apoptotic protein that upregulates upon stress and improves stem cell resilience, resulting in enhanced regenerative abilities in its host.'
cell.com
Host-transposon mutualism supports regeneration in planarians
Lee et al. find that the planarian transposon Burro1 bolsters stem cell resilience by producing a functional host-derived caspase inhibitor during physiological stress. By suppressing apoptosis, activ...
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Petra Korlević @petrathepostdoc.bsky.social · 22/05/2026
guess who got accepted! 📝 fancy formatted PDF incoming, unformatted final submission now available for your reading pleasure, and maybe keep in mind for your next sample shipping, skip on the dry ice and save moneys while still making beautiful reference genomes! academic.oup.com/gigascience/...
academic.oup.com
Breaking the cold chain: solutions for room temperature preservation of mosquitoes leading to high quality reference genomes
AbstractBackground. The Earth BioGenome Project (EBP) is a global endeavour to produce reference genomes for all described eukaryotic species. The majority
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BK. Titanji @boghuma.bsky.social · 19/05/2026
Important to read the seminal paper on the discovery of the Bundibugyo virus. It is a different species from Zaire Ebola virus, differing in its genome by up to 32%. The vaccines and monoclonal antibodies for Zaire virus are unlikely to be effective here. journals.plos.org/plospathogen...
journals.plos.org
Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
Author Summary In this report we describe a newly discovered ebolavirus species which caused a large hemorrhagic fever outbreak in western Uganda. The virus is genetically distinct, differing by more ...
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Kristian G. Andersen @kgandersen.bsky.social · 18/05/2026
Amazing speed from the teams in Uganda and the DRC - impressive! Three genomes released so far - a few quick takes: 1️⃣ New genomes ~equidistant from 2007 and 2012 outbreaks. 2️⃣ Represents new spillover from reservoir. 3️⃣ Limited diversity, so too early to speculate on timing. Great work ⭐!
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 18/05/2026
Great that Uganda has rapidly shared #Ebola genomic sequence data. Fast, transparent data sharing is vital for surveillance & accelerating medical countermeasures esp for Bundibugyo where there are no vaccines & therapeutics. This is global scientific collaboration pathoplexus.org/ebola-bdbv/s...
pathoplexus.org
Pathoplexus | Ebola Bundibugyo - Browse
Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.
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BK. Titanji @boghuma.bsky.social · 17/05/2026
Bundibugyo ebolavirus outbreak in the DRC and Uganda has been declared a PHEIC by the WHO. The highest alert lever it has. This requires swift a and multinational response. Estimated death count is already 80! No vaccine, no rapid diagnostic tests. www.science.org/content/arti...
science.org
BREAKING: WHO declares major outbreak of rare Ebola virus species in Congo and Uganda an international emergency
No vaccines or treatments exist for Ebola Bundibugyo, which has caused hundreds of suspected cases and 80 deaths; WHO warns of
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public health guy @publichealthguy1.bsky.social · 17/05/2026
my heart hurts tonight for the hundreds already harmed by this ebola outbreak. thinking of everyone at risk in the region, especially the responders and healthcare workers from the drc and uganda who are working to save lives/stop the spread under extremely difficult and dangerous conditions
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