Nature Reviews Chemistry, Published online: 24 September 2026; doi:10.1038/s41570-026-00881-0Chemistry is a strategically vital UK strength and underpins many of the sectors identified as priorities for future growth. Yet despite its economic significance and continued demand for the skills it supplies, chemistry is facing structural pressures that need serious attention from universities, funders and governments across the UK.

Nature Reviews Chemistry, Published online: 29 September 2026; doi:10.1038/s41570-026-00878-9This Review examines how the dynamic solid electrolyte interphase governs lithium-mediated ammonia synthesis and highlights complementary operando, in situ and multiscale characterization strategies to resolve the composition, structure and evolution of the former, guiding rational solid electrolyte interphase design for improved efficiency, selectivity and durability.

Nature Reviews Chemistry, Published online: 23 September 2026; doi:10.1038/s41570-026-00880-1Mahshab Sheraz explains how a custom photocatalytic column reactor integrates capturing volatile organic compounds, light-driven filter regeneration and humidity effects, enabling realistic continuous-flow evaluation of reusable filter membranes for cleaner indoor air.

Nature Reviews Chemistry, Published online: 28 September 2026; doi:10.1038/s41570-026-00882-zSingle-atom catalysis has triggered an enormous research boom. However, inconsistent terminology is widely encountered in the literature, particularly for single-atom versus single-site catalysts. By clarifying the origins of these catalysts, and distinguishing their criteria and structural boundaries, this Comment proposes standardized characterization benchmarks and writing norms to unify terminology.

Nature Reviews Chemistry, Published online: 29 September 2026; doi:10.1038/s41570-026-00878-9This Review examines how the dynamic solid electrolyte interphase governs lithium-mediated ammonia synthesis and highlights complementary operando, in situ and multiscale characterization strategies to resolve the composition, structure and evolution of the former, guiding rational solid electrolyte interphase design for improved efficiency, selectivity and durability.

Nature Reviews Chemistry, Published online: 28 September 2026; doi:10.1038/s41570-026-00882-zSingle-atom catalysis has triggered an enormous research boom. However, inconsistent terminology is widely encountered in the literature, particularly for single-atom versus single-site catalysts. By clarifying the origins of these catalysts, and distinguishing their criteria and structural boundaries, this Comment proposes standardized characterization benchmarks and writing norms to unify terminology.

Nature Reviews Chemistry, Published online: 21 September 2026; doi:10.1038/s41570-026-00875-yThe formation and interfacial transfer of reactive hydrogen species (H+, H· and Hδ−) is crucial for various reactions and systems, such as hydrogen evolution, hydrogenation and fuel cells. Understanding these transfer pathways is key when designing next-generation catalysts capable of precisely controlling hydrogen dynamics.

Nature Reviews Chemistry, Published online: 25 September 2026; doi:10.1038/s41570-026-00877-wThe lack of a unified framework for aromaticity often prevents cross-disciplinary comprehension. By summarizing fundamental concepts and highlighting recent developments in excited-state, 3D and metallaaromaticity, this Review bridges these conceptual gaps to foster a holistic understanding.

Nature Reviews Chemistry, Published online: 24 September 2026; doi:10.1038/s41570-026-00881-0Chemistry is a strategically vital UK strength and underpins many of the sectors identified as priorities for future growth. Yet despite its economic significance and continued demand for the skills it supplies, chemistry is facing structural pressures that need serious attention from universities, funders and governments across the UK.

Nature Reviews Chemistry, Published online: 25 September 2026; doi:10.1038/s41570-026-00877-wThe lack of a unified framework for aromaticity often prevents cross-disciplinary comprehension. By summarizing fundamental concepts and highlighting recent developments in excited-state, 3D and metallaaromaticity, this Review bridges these conceptual gaps to foster a holistic understanding.

Nature Reviews Chemistry, Published online: 18 September 2026; doi:10.1038/s41570-026-00879-8Dopamine is usually thought of as a ligand that binds to a receptor. However, a recent study demonstrated that dopamine also dynamically interacts with a lipid bilayer by binding to the membrane’s surface and bending the acyl chains of the lipids on the outer leaflet.

Nature Reviews Chemistry, Published online: 23 September 2026; doi:10.1038/s41570-026-00880-1Mahshab Sheraz explains how a custom photocatalytic column reactor integrates capturing volatile organic compounds, light-driven filter regeneration and humidity effects, enabling realistic continuous-flow evaluation of reusable filter membranes for cleaner indoor air.

Nature Reviews Chemistry, Published online: 24 September 2026; doi:10.1038/s41570-026-00881-0Chemistry is a strategically vital UK strength and underpins many of the sectors identified as priorities for future growth. Yet despite its economic significance and continued demand for the skills it supplies, chemistry is facing structural pressures that need serious attention from universities, funders and governments across the UK.

Nature Reviews Chemistry, Published online: 23 September 2026; doi:10.1038/s41570-026-00880-1Mahshab Sheraz explains how a custom photocatalytic column reactor integrates capturing volatile organic compounds, light-driven filter regeneration and humidity effects, enabling realistic continuous-flow evaluation of reusable filter membranes for cleaner indoor air.

Nature Reviews Chemistry, Published online: 21 September 2026; doi:10.1038/s41570-026-00875-yThe formation and interfacial transfer of reactive hydrogen species (H+, H· and Hδ−) is crucial for various reactions and systems, such as hydrogen evolution, hydrogenation and fuel cells. Understanding these transfer pathways is key when designing next-generation catalysts capable of precisely controlling hydrogen dynamics.

Nature Reviews Chemistry, Published online: 21 September 2026; doi:10.1038/s41570-026-00875-yThe formation and interfacial transfer of reactive hydrogen species (H+, H· and Hδ−) is crucial for various reactions and systems, such as hydrogen evolution, hydrogenation and fuel cells. Understanding these transfer pathways is key when designing next-generation catalysts capable of precisely controlling hydrogen dynamics.

Nature Reviews Chemistry, Published online: 18 September 2026; doi:10.1038/s41570-026-00879-8Dopamine is usually thought of as a ligand that binds to a receptor. However, a recent study demonstrated that dopamine also dynamically interacts with a lipid bilayer by binding to the membrane’s surface and bending the acyl chains of the lipids on the outer leaflet.

Nature Reviews Chemistry, Published online: 18 September 2026; doi:10.1038/s41570-026-00879-8Dopamine is usually thought of as a ligand that binds to a receptor. However, a recent study demonstrated that dopamine also dynamically interacts with a lipid bilayer by binding to the membrane’s surface and bending the acyl chains of the lipids on the outer leaflet.

Nature Reviews Chemistry, Published online: 11 September 2026; doi:10.1038/s41570-026-00865-0Ionizable lipids represent central components in nucleic acid therapeutics. This Review outlines their structural evolution, design strategies and emerging functions while highlighting next-generation principles and translational perspectives that may guide precision RNA therapeutics in regenerative medicines.

Nature Reviews Chemistry, Published online: 10 September 2026; doi:10.1038/s41570-026-00873-0Aqueous–organic reaction media contain dynamic colloidal structures that strongly influence reactivity and selectivity yet remain difficult to characterize. This Perspective discusses outstanding mechanistic questions, evaluates available analytical tools and identifies routes towards a predictive framework for reaction development in water.

Nature Reviews Chemistry, Published online: 08 September 2026; doi:10.1038/s41570-026-00874-zThis article highlights a newly developed chemically fuelled logic gate whereby a single porphyrin dye is driven by two independent enzyme reactions, one setting its colour and the other its fluorescence. Because the two outputs recover on separately tunable timescales, the system produces a programmable delay of up to about 23 minutes between them, letting the researchers control not just whether a signal appears but when.

Nature Reviews Chemistry, Published online: 07 September 2026; doi:10.1038/s41570-026-00876-xBruno Pinheiro explains the workings of their custom-made apparatus for measuring vapour pressures with high accuracy within large pressure and temperature ranges.

Nature Reviews Chemistry, Published online: 11 September 2026; doi:10.1038/s41570-026-00865-0Ionizable lipids represent central components in nucleic acid therapeutics. This Review outlines their structural evolution, design strategies and emerging functions while highlighting next-generation principles and translational perspectives that may guide precision RNA therapeutics in regenerative medicines.

Nature Reviews Chemistry, Published online: 10 September 2026; doi:10.1038/s41570-026-00873-0Aqueous–organic reaction media contain dynamic colloidal structures that strongly influence reactivity and selectivity yet remain difficult to characterize. This Perspective discusses outstanding mechanistic questions, evaluates available analytical tools and identifies routes towards a predictive framework for reaction development in water.

Nature Reviews Chemistry, Published online: 11 September 2026; doi:10.1038/s41570-026-00865-0Ionizable lipids represent central components in nucleic acid therapeutics. This Review outlines their structural evolution, design strategies and emerging functions while highlighting next-generation principles and translational perspectives that may guide precision RNA therapeutics in regenerative medicines.

Nature Reviews Chemistry, Published online: 10 September 2026; doi:10.1038/s41570-026-00873-0Aqueous–organic reaction media contain dynamic colloidal structures that strongly influence reactivity and selectivity yet remain difficult to characterize. This Perspective discusses outstanding mechanistic questions, evaluates available analytical tools and identifies routes towards a predictive framework for reaction development in water.

Nature Reviews Chemistry, Published online: 08 September 2026; doi:10.1038/s41570-026-00874-zThis article highlights a newly developed chemically fuelled logic gate whereby a single porphyrin dye is driven by two independent enzyme reactions, one setting its colour and the other its fluorescence. Because the two outputs recover on separately tunable timescales, the system produces a programmable delay of up to about 23 minutes between them, letting the researchers control not just whether a signal appears but when.

Nature Reviews Chemistry, Published online: 07 September 2026; doi:10.1038/s41570-026-00876-xBruno Pinheiro explains the workings of their custom-made apparatus for measuring vapour pressures with high accuracy within large pressure and temperature ranges.

Nature Reviews Chemistry, Published online: 08 September 2026; doi:10.1038/s41570-026-00874-zThis article highlights a newly developed chemically fuelled logic gate whereby a single porphyrin dye is driven by two independent enzyme reactions, one setting its colour and the other its fluorescence. Because the two outputs recover on separately tunable timescales, the system produces a programmable delay of up to about 23 minutes between them, letting the researchers control not just whether a signal appears but when.

Nature Reviews Chemistry, Published online: 07 September 2026; doi:10.1038/s41570-026-00876-xBruno Pinheiro explains the workings of their custom-made apparatus for measuring vapour pressures with high accuracy within large pressure and temperature ranges.

Nature Reviews Chemistry, Published online: 25 August 2026; doi:10.1038/s41570-026-00872-1A 2026 public survey suggests that organic chemistry (o-chem) remains underappreciated and misunderstood in the modern era — is it finally time to take action?

Nature Reviews Chemistry, Published online: 24 August 2026; doi:10.1038/s41570-026-00871-2Mycobacterial drug discovery is held back by the challenge of limited compound penetration across the mycomembrane. An experimentally enabled machine-learning approach identifies permeability-promoting molecular features that could help guide medicinal chemistry toward more permeable antibacterial candidates.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00864-1Conventional drug design lacks the spatial control needed for the selective targeting of mislocalized proteins, a pervasive phenomenon with diseases. This Perspective discusses how subcellular photochemistry combined with a prodrug approach can target those conserved proteins precisely.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00870-3Devendra Pal explains how their custom-made ice nucleation chamber works, yielding data on nucleation itself as well as particle sizes, phases, and morphologies in an effort to understand cloud formation and its impact on atmospheric chemistry.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00867-yThis Review surveys emerging chemical and biophysical tools for detection, characterization and intervention of soluble misfolded oligomers. These small oligomers are considered the main disease-causing species for amyloid diseases. Targeting these oligomers is highlighted as a promising research direction.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00866-zThis Review discusses molten salt electrochemistry for energy storage systems, covering electrolyte chemistry, charge storage, cell configurations and materials innovations, and points to future opportunities in cathode design, ion-selective membranes and advanced molten salt systems.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00869-wAhead of her 65th birthday, Margaret Brimble, Distinguished Professor and Director of Medicinal Chemistry at the University of Auckland, discussed her life in science.

Nature Reviews Chemistry, Published online: 25 August 2026; doi:10.1038/s41570-026-00872-1A 2026 public survey suggests that organic chemistry (o-chem) remains underappreciated and misunderstood in the modern era — is it finally time to take action?

Nature Reviews Chemistry, Published online: 24 August 2026; doi:10.1038/s41570-026-00871-2Mycobacterial drug discovery is held back by the challenge of limited compound penetration across the mycomembrane. An experimentally enabled machine-learning approach identifies permeability-promoting molecular features that could help guide medicinal chemistry toward more permeable antibacterial candidates.

Nature Reviews Chemistry, Published online: 25 August 2026; doi:10.1038/s41570-026-00872-1A 2026 public survey suggests that organic chemistry (o-chem) remains underappreciated and misunderstood in the modern era — is it finally time to take action?

Nature Reviews Chemistry, Published online: 24 August 2026; doi:10.1038/s41570-026-00871-2Mycobacterial drug discovery is held back by the challenge of limited compound penetration across the mycomembrane. An experimentally enabled machine-learning approach identifies permeability-promoting molecular features that could help guide medicinal chemistry toward more permeable antibacterial candidates.

Nature Reviews Chemistry, Published online: 17 August 2026; doi:10.1038/s41570-026-00862-3Volatile methyl siloxanes are synthetic compounds that readily partition to the atmosphere and have been a focus of policy debates. This Review discusses advances in understanding the atmospheric chemistry, lifetimes and abundancies of these compounds and their oxidation products.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00864-1Conventional drug design lacks the spatial control needed for the selective targeting of mislocalized proteins, a pervasive phenomenon with diseases. This Perspective discusses how subcellular photochemistry combined with a prodrug approach can target those conserved proteins precisely.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00870-3Devendra Pal explains how their custom-made ice nucleation chamber works, yielding data on nucleation itself as well as particle sizes, phases, and morphologies in an effort to understand cloud formation and its impact on atmospheric chemistry.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00867-yThis Review surveys emerging chemical and biophysical tools for detection, characterization and intervention of soluble misfolded oligomers. These small oligomers are considered the main disease-causing species for amyloid diseases. Targeting these oligomers is highlighted as a promising research direction.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00866-zThis Review discusses molten salt electrochemistry for energy storage systems, covering electrolyte chemistry, charge storage, cell configurations and materials innovations, and points to future opportunities in cathode design, ion-selective membranes and advanced molten salt systems.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00869-wAhead of her 65th birthday, Margaret Brimble, Distinguished Professor and Director of Medicinal Chemistry at the University of Auckland, discussed her life in science.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00864-1Conventional drug design lacks the spatial control needed for the selective targeting of mislocalized proteins, a pervasive phenomenon with diseases. This Perspective discusses how subcellular photochemistry combined with a prodrug approach can target those conserved proteins precisely.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00870-3Devendra Pal explains how their custom-made ice nucleation chamber works, yielding data on nucleation itself as well as particle sizes, phases, and morphologies in an effort to understand cloud formation and its impact on atmospheric chemistry.

Nature Reviews Chemistry, Published online: 20 August 2026; doi:10.1038/s41570-026-00866-zThis Review discusses molten salt electrochemistry for energy storage systems, covering electrolyte chemistry, charge storage, cell configurations and materials innovations, and points to future opportunities in cathode design, ion-selective membranes and advanced molten salt systems.