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Jayati Sharma, PhD, ScM

@jayatirsharma.bsky.social
328 followers 494 following 68 posts

📊 epidemiologist 🧬 genetics, envt, & public health in diverse pops 💻 postdoc @ NCI 📝 editor @genebites.org | AAAS MMF alum pronounced “JAY-uh-tea” all views my own

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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 06/10/2026
Super exciting findings and promising transferrable methods to do some impactful meta-science and bioethics work. More evidence to my belief that Roshni’s most interesting paper is always the next one! 🙂‍↕️
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Roshni Patel @roshnipatel.bsky.social · 06/10/2026
So excited about this work with @nasalab.bsky.social! Led by Stephanie Gogarten & with help from @daphmarts.bsky.social, we use LLMs as judges to evaluate the use of population descriptors in the entirety of the GWAS Catalog (~4,000 papers published 2007-2025) www.biorxiv.org/content/10.6...
biorxiv.org
Large language model-based bibliometric evaluation of population descriptors in human genetics
As the use of population descriptors such as race, ethnicity, and ancestry have become increasingly common in modern genetics research, there have been growing calls to critically examine their use. M...
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Roshni Patel @roshnipatel.bsky.social · 06/10/2026
But, this also illustrates the importance of bottom-up change: decades of work by individual researchers across the field have systematically improved our use of population descriptors in human genetics and genomics. We need to continue to invest in these efforts -- ethics and rigor are intertwined!
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 01/10/2026
Come pitch us a fun new genetics story @ GeneBites! All flavors of genetics welcome.
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Roshni Patel @roshnipatel.bsky.social · 14/09/2026
These are of course very old questions with tremendous recent progress; we focus mostly on the recent progress and what it offers for the next era of studying human genetics in biobanks. Excited this preprint is out and we'd of course love to hear any thoughts!
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 15/09/2026
they know ball!
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Gen Wojcik @genandgenes.bsky.social · 19/08/2026
Genetics matter, but are not determinative for many many human traits. Even if genetics do influence health (or life in general), they do not influence someone's worth as a human being. Genetics just are. They are not good, they are not bad. They just are.
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Liz Neeley @lizneeley.bsky.social · 06/08/2026
A scientist who just lost her grant cuts straight to the heart of it: “Requiring that NIH only fund work leading directly to a drug or other biomedical intervention… would rule out much basic research funded by the agency.” It’s pathetic & harmful to limit our understanding of health like this
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 03/08/2026
a lot of science communicators are actually trained to not stay in their area of expertise and instead promoted to be generalists! ask me how i know. this is of course bad, but it is how “people” think scicomm should be. remembering all the covid era science influencers who had 0 epi training.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 14/07/2026
ok but hear me out this should be your new pfp. (also im dying at the alt text)
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Christa Caggiano @christacaggiano.bsky.social · 09/07/2026
Working on this project was so fun! ❤️ It's really awesome to work with so many passionate scientists who are all committed to improving our field (despite a climate that might not always be so friendly to that) We'd love any feedback, especially from other trainees and early career researchers!
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Roshni Patel @roshnipatel.bsky.social · 07/07/2026
I think this work really underscores that we are at a turning point in human genetics. There is a growing consensus that doing good research in human genetics requires an expanded skillset (including, e.g., one that can navigate the relationship between genetics, ancestry, and pop descriptors) (1/)
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
🫶🏼🫡
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
pls excuse any and all typos in this thread lol, too excited to proofread!
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bioRxiv Genetics @biorxiv-genetic.bsky.social · 07/07/2026
Recommendations for the ethical and accurate use of population descriptors: a trainee-led survey of early-career researchers www.biorxiv.org/content/10.64898/20…
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
Tagging the rest of our rockstar team here: @raungar.bsky.social @jpflores.rbind.io @alvinahere.bsky.social @tamigj.bsky.social @dianexue.bsky.social & (untaggable) Krystin Jones, Betzaida Maldonado, and Alyna Khan.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
This work would not have been impossible without the immense efforts of the entire team that helped design, pilot, distribute, interpret, analyze, write & edit. Special thanks to my co-correspondents Roshni @ @christacaggiano.bsky.social for their significant commitments to taking our work this far!
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
I remember pitching a commentary-style ELSI piece on this topic to @raungar.bsky.social & @roshnipatel.bsky.social 2+ yrs ago as a late stage grad student w lofty ambitions. Building this all-trainee (at the time) team and has been a real gift for me! So lucky to work with so many like-minded folks.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
Thank you to our survey participants for their very thorough responses to our survey that helped support many of the recommendations that we’ve put forth. Many thanks to @daphmarts.bsky.social, @eimearekenny.bsky.social, & @genandgenes.bsky.social for their support, review, & thoughtful comments.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
To address these, we offer actionable, stakeholder-specific recommendations across the research lifecycle ranging from decision-support tools to "bring-your-own-data" workshops to leadership and trainee mentors. Please read our preprint and let us know your thoughts! www.biorxiv.org/content/10.6...
biorxiv.org
Recommendations for the ethical and accurate use of population descriptors: a trainee-led survey of early-career researchers
Despite the importance of population descriptors in human genomics research, many scientists struggle to translate evolving ethical guidelines into their computational workflows. To characterize this ...
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
We found that while exposure to the report fosters ethical awareness, fundamental misconceptions about race and ancestry persist across disciplines. Trainees reported structural bottlenecks, including legacy data constraints and a lack of technical confidence in implementing NASEM guidelines.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
Motivated by our own experience as current trainees and early career researchers (ECRs), we'd seen many ECRs struggle to actually implement the NASEM report recommendations in their work. We wanted to better characterize the reasons for that across the field of computational human genetics.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 07/07/2026
In what has been a labor of love & joyful collaboration, we are super excited to share our preprint on recommendations towards the ethical and accurate use of population descriptors generated from a survey by trainees, for trainees. www.biorxiv.org/content/10.6...
biorxiv.org
Recommendations for the ethical and accurate use of population descriptors: a trainee-led survey of early-career researchers
Despite the importance of population descriptors in human genomics research, many scientists struggle to translate evolving ethical guidelines into their computational workflows. To characterize this ...
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Satoshi Yoshiji, MD, PhD @satoshiyoshiji.bsky.social · 30/06/2026
NIH All of Us has just released a massive multi-omics dataset, including: • 535K WGS (120K+ added; now larger than UKB) • ~10K proteomics + RNAseq + long-read • ML-curated clinical notes • 68K with Fitbit data Kudos to this great initiative and to the participants for advancing science
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Nonia Pariente @npariente.bsky.social · 29/06/2026
"The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. Replacing one prestige filter with another that is harder to see or challenge is not progress toward equity in science; it’s the opposite.” 💯🧪
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 16/06/2026
this is extremely good. my current writing playlist is dominated by ridgeclub & KatzPascale 🎷🎧
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John Delmenico @thebigjohnnyd.bsky.social · 14/06/2026
Mamdani’s New York is having the kind of run that you normally only see in a montage at the end of a Disney Channel movie
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 03/06/2026
did u know that out of the 12,000 data centers in the world over 4,000 are in the US of A? 😀
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Elise Cutts @elisecutts.bsky.social · 28/05/2026
Hey Europe: AC saves lives Hey USA: Gun control saves lives Chart by @hannahritchie.bsky.social (see below)
A plot of heat versus gun deaths in Europe and the United States per 100,000 population in 2024. Heat deaths are excess deaths, not deaths recorded as "heat deaths" on death certificates. It is a bar chart. Heat deaths in orange, gun deaths in blue. From left to right the bars are: US — heat (1.94 deaths/100,000 pop); Europe — guns (1.20 deaths/100,000 pop); US — guns (13.27 deaths/100,000 pop, with about 1/3 of those being shaded to show they are homicides vs suicides); Europe — heat (11.22 deaths/100,000 pop).

The chart shows that gun deaths in the US and heat deaths in Europe are pretty close in frequency per capita. Europe is good at protecting people from gun violence, the US is good at protecting people from heat deaths.
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 24/05/2026
I miss Twitter, mostly because the conversation there for a brief period was so wide-ranging, could be non-hierarchical and forced me to consider view points different than mine. now all of that is splintered between Twitter, Bluesky and threads (😭😭), which feels like a real loss.
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Ran Blekhman @blekhman.bsky.social · 21/05/2026
"This is why LLM AI will not solve cancer or climate change. Those problems require long time horizons, willingness to fail publicly, cooperations across competitors, and subordination of short-term returns to outcomes that may take decades to materialize." www.tomorrowsmess.com/p/the-fox-an...
tomorrowsmess.com
The Fox and the Hedgehog
Americans are catching on to Silicon Valley's 'One Weird Trick'
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 21/05/2026
someday far in the future we will tell children of the mystical Google dot com of decades past: a place where we could ask a question and be directed to at least several dozen factual and valuable* answers written by other real people with actual experience
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Eric Turkheimer @ent3c.bsky.social · 18/05/2026
A Substack post on the Nature Human Genetics article. The piece itself is very short, so it is sort of a summary of a summary.
ericturkheimer.substack.com
Polygenic Scores Are Not Genetic Predispositions
Language matters
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Sandy Ernest Allen @sandyernestallen.bsky.social · 14/05/2026
Trans people are being forced to flee red states and for the most part, the press has ignored this story.
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 14/05/2026
relatable queen
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ashlee, mph @avs.bsky.social · 07/05/2026
did you know i am doing a dissertation on workplace leave use among full-time workers in the US who have experienced miscarriage? well now you do! and if you think you may be eligible, you can take a screener survey at go.uic.edu/leavestudy or scan the QR code. #reprosky #healthpolicy #miscarriage
An image of a pair of hands being held while a clipboard is in one person's lap. The text to the side indicates Participants Needed for a research study on miscarriage and workplace leave policy use among full-time workers. People are eligible to participate if they have experienced a miscarriage at or before 20 weeks gestation, 18+ years of age, they were working full-time at the time of loss, were living and working in the United States, can read and write in English, and have internet access.

Participation requires completion of an eligibility screener that takes roughly 5 minutes and if deemed eligible, will be sent an invitation to the full survey which should take up to 20 minutes. Participants can either scan a QR code or go to go.uic.edu/leavestudy

If people have questions or concerns about participating, they can contact Ashlee Van Schyndel (avansc6@uic.edu) or Dr. Alisa Velonis (avelonis@uic.edu)
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 06/05/2026
brb making this a laptop sticker
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Jeremy Berg @jeremymberg.bsky.social · 04/05/2026
I just repeated the analysis for grants in fiscal year 2026. I found 98 grants with title changes upon administrative (non-competitive) renewal. Here is the removed word cloud for fiscal year 2026. 4/5
A word cloud of words removed from NIH grant titles in fiscal year 2026. The most commonly removed words are "equity", "diverse", "disparate", "racial", "gender, and similar terms.
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In These Times @inthesetimes.com · 04/05/2026
May Day wasn’t just a day of protest, boycott or celebration. It was a reminder that workers make the world run—and that we’re all on the same team. @hamiltonnolan.bsky.social reports. inthesetimes.com/article/may-...
Screenshot of an In These Times article card in the Labor section. The headline reads, “May Day Was a Reminder That We Make the World Run.” Below is a photo of May Day demonstrators marching in a city street, including workers in orange safety vests and members of Laborers’ International Union of North America Local 79. Several people hold signs, including one that says “An injury to one is an injury to all.” The subheadline reads, “It wasn’t just a day of protest, boycott or celebration—May Day showed that we, the workers, are all on the same glorious team.” The byline is Hamilton Nolan.
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Kevin Bird @stairwaytokevin.bsky.social · 01/05/2026
Wow shocker, the eugenics company doesn't care much about actually seeing if their snakeoil worked
nymag.com
Are ‘Designer Babies’ a Scam?
Anxious parents are buying $50,000 genetic tests that might not be worth much of anything.
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Ying Wang @yingwangyw.bsky.social · 23/04/2026
🎉New preprint: Phenome-derived polygenic scores and social determinants jointly shape context-dependent disease risk. We evaluate disease risk along 2 complementary axes: • how genetic liability is represented • the social context in which it is expressed
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xueyaowu.bsky.social @xueyaowu.bsky.social · 20/04/2026
Excited to share our recent paper in #npjBreastCancer! We investigated what drives the AI-generated mammogram risk score (MRS)—a texture feature that predicts breast cancer risk beyond breast density. A thread 👇 @peter-kraft.bsky.social
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 25/03/2026
gave my first official guest lecture today & have renewed hope in the future. the difference an engaged and curious classroom can make! 🙂‍↕️ even when the lecture is on molecular epidemiology 🔬
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Jonathan Wosen @jonathanwosen.bsky.social · 19/03/2026
@statnews.com conducted a national survey of NIH-funded researchers and found that, a year after Trump's return, many scientists are reeling, with some closing labs entirely. ‘This is like the Titanic,' one respondent told me. For full details, see our special report www.statnews.com/2026/03/19/n...
statnews.com
National survey of NIH-funded researchers shows precarious state of U.S. science — ‘This is like the Titanic’
A nationwide STAT survey of NIH-funded researchers reveals that, a year after Donald Trump's return to the White House, many scientists are reeling
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 18/03/2026
Finger on the pulse: “Embedding communication and policy fluency into STEM training is not about adding polish. It is about responsibility. Students should graduate knowing not only how to generate knowledge, but how to explain it, contextualize it, and respond when it is misunderstood or misused.”👏
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Paul Noth @paulnoth.bsky.social · 23/02/2026
Mine in this week’s @newyorker.com
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GeneBites @genebites.org · 11/02/2026
Happy #InternationalDayofWomenandGirlsinScience!
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 31/01/2026
another great read — this time on antibiotic resistance — from the talented @amandan-weiss.bsky.social (who’s also our new Social Media Editor)!! genebites.org/2026/01/30/a...
genebites.org
Answer the (KlebPha)Col: a new community resource for Klebsiella phage research
As bacteria evolve to become more resistant to antibiotics, scientists are revisiting “phage therapy” (using natural viruses that destroy bacteria) as an avenue for treating infections. A new commu…
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 31/01/2026
or this one on epigenetics and trauma from @pattersonhabitat.bsky.social ‘s ongoing series “Decoding Life”!! genebites.org/2026/01/27/d...
genebites.org
Decoding Life: The Echo of Trauma
It’s time to dig a little deeper into some newer genetics concepts. Previously in this series, we have explored the ins and outs of cell division and other genetic processes as a way to dive …
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Jayati Sharma, PhD, ScM @jayatirsharma.bsky.social · 31/01/2026
Despite *gestures broadly*, one bright light for me has been reading and editing so many wonderful pieces from our team at GeneBites on our corner of the internet, like this great one from @jpflores.rbind.io 🐭👇🏼
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