Plasmid construction underpins molecular biology and synthetic biology, yet validation is often limited to the inserted fragment rather than the whole plasmid, and around a third of laboratory-made pl...

Plasmid construction underpins molecular biology and synthetic biology, yet validation is often limited to the inserted fragment rather than the whole plasmid, and around a third of laboratory-made pl...

Existing notions of pangenome coordinates rely on hard-to-compute multiple sequence alignments. On the other hand, pangenome-wide exact unique matches (multi-MUMs) can be computed efficiently, and rep...

AbstractMotivation. The increasing number of fully sequenced bacterial plasmids being annotated and catalogued has prompted the development of computationa

Abstract. Synthetic biology and metabolic engineering increasingly demand predictable and interoperable gene expression across phylogenetically distant org

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CRISPR-Cas provides RNA-mediated adaptive immunity, but how its first RNA-guided effector arose is unclear. In this study, we report the discovery of Viral Interference Programmable Repeat (VIPR) syst...

Abstract. C4 photosynthetic syndromes have evolved multiple times from ancestral C3 photosynthetic pathways. The genus Flaveria has served as a model group

A small, spotted tiger cat from Bolivia may just be the beginning of a wave of new small cat species.

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11057-7Rhynchospora tenuis undergoes obligate, genome-wide achiasmy in both male and female meiosis.

Biological sciences; Molecular biology; Molecular mechanism of gene regulation; Neuroscience; Plant biology

Researchers are racing to culture a menagerie of exotic organisms and finding lots of surprises along the way.

Rhynchospora tenuis undergoes obligate, genome-wide achiasmy in both male and female meiosis.

Screen limits will become mandatory in NSW schools from 2028 as federal education minister says students may need a ‘digital detox’ * Follow our Australia news live blog for latest updates * Get our new political email, free app or daily news podcast The New South Wales government has announced it will implement limits on screen time in public school classrooms and push for students to take part in daily “pen and paper” learning. The state’s new regulations follow a similar announcement from the Victorian government and suggestions by the federal education minister, Jason Clare, that students might need a “digital detox”. Sign up for Guardian Australia’s Politics, really newsletter here Continue reading...

Recent technological breakthroughs have transformed our understanding of how transcription initiation in eukaryotes is regulated. This Review discusses the dynamics and roles of initiation-relevant pr...

In this Review, James et al. provide an overview of approaches for planning, constructing, and fine-tuning synthetic genomes and describe their potential applications.