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Ignacio Vega-Vásquez

@igvegvas.bsky.social
242 followers 976 following 11 posts

From Coyhaique to Würzburg. Biochemist, PhD on 🧠🔬 in progress. In BlueSky only for cahuines (and the papers)

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Reposted by Ignacio Vega-Vásquez
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 27/08/2026
Very happy to see our Nature Reviews Molecular Cell Biology Roadmap out! A fantastic collective effort, led by Carsten Janke and Zdenek Lansky, together with an amazing group of colleagues, and sparked by inspiring discussions at the Fondation des Treilles. www.nature.com/articles/s41...
nature.com
Towards a systems-level view of the microtubule cytoskeleton and its functions in physiology and disease - Nature Reviews Molecular Cell Biology
Microtubules are essential components of the cytoskeleton, yet important links between their molecular properties and organismal functions remain unresolved. In this Roadmap, Janke et al. discuss key ...
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Ignacio Vega-Vásquez @igvegvas.bsky.social · 13/08/2026
(1/4) Last, but not least: how do mitochondria look like with #MegaExM? First, thank you Jorge for providing your expertise in this topic and how to deal with all these data! He already shared what a 10X air lens can capture in his latest post. But what about 40X 1.2 NA water lens?
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cryoEM papers @cryoempapers.bsky.social · 07/08/2026
Structural cell biology by mega-expansion microscopy www.biorxiv.org/content/10.64898/2026.08.05.743040v1 #cryoEM
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jorgetoledoh @jorgetoledoh.bsky.social · 12/08/2026
(1/5) Individual mitochondrial cristae with a 10X air lens 🤯 I am very happy to be a co-author on Mega-ExM! Driven by @igvegvas.bsky.social at @sauer-lab.bsky.social . It is really exciting to see how far Ignacio has pushed the technique since we learned it together back in 2019.
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Camila García-Navarrete @camig98.bsky.social · 10/08/2026
(2/3) As an example, here's a first look at cilia and basal bodies in a multiciliated cell expanded 250x! A 1.25×1.25x0.59 mm volume (≈ 5×5x2.4 µm, PreExM), acquired with a 10X air lens (undersampled), but yet so much detail! Stainings: NHS (magenta) / CEP83 (cyan) / Acet. tub. (orange).
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Ali Shaib @alishaib.bsky.social · 11/08/2026
our 5th paper of 2026 is out: ONE microscopy www.nature.com/articles/s41... #Protein shapes, #sub-nanometer precision, conventional #fluorescence #microscopes, and now #ONEpy. 3 more papers in revision, more this year. We’re only getting started. #optical #structural #biology is becoming a field
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Camila García-Navarrete @camig98.bsky.social · 10/08/2026
(1/3) For all centrosome/cilia enthusiasts 🗣️🗣️ From Pereira’s lab, we’re so happy to share our latest collab with @sauer-lab.bsky.social: Mega-ExM)! 🥳 Here, we pushed expansion microscopy to crazy scales (1500x 🤯) and used cilia and centrioles as some of our favorite test structures 🤭
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Ignacio Vega-Vásquez @igvegvas.bsky.social · 10/08/2026
Centrosome/cilia people 🗣🗣 Multiciliated cells by Mega-ExM with a 10X air lens 😶‍🌫️ (Plan-Apochromat, 0.45 N.A.); voxel: 1.248 μm x 1.248 μm x 4 μm, sampling 0.21x. Airyscan2 LSM900 Zeiss. Thank you Camila and Gislene for this awesome collab!
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Ali Shaib @alishaib.bsky.social · 07/08/2026
Exciting new preprint from Ignacio Vega Vásquez, Sauer lab, my team and collaborators: #Mega-ExM. From just ~20 NPCs imaged with a 10× objective on a confocal, we reconstructed the 3D structure at ~33 Å. A step toward optical structural biology in intact cells. www.biorxiv.org/content/10.6...
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Ignacio Vega-Vásquez @igvegvas.bsky.social · 07/08/2026
(1/4) We are very excited to share our latest preprint from @sauer-lab.bsky.social: Mega Expansion Microscopy (Mega-ExM)! We combine iterative hydrogel expansion with whole-proteome NHS labeling and post-expansion immunostaining, reaching tunable expansion factors up to ~1500× in whole cells 🤯
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bioRxiv Biophysics @biorxiv-biophys.bsky.social · 07/08/2026
Structural cell biology by mega-expansion microscopy www.biorxiv.org/content/10.64898/20…
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Camila García-Navarrete @camig98.bsky.social · 14/07/2026
Excited to share our latest paper in Gislene Pereira’s lab about how extracellular matrix stiffness affect ciliogenesis c: check it out here: doi.org/10.1038/s415...
doi.org
Soft matrix promotes ciliogenesis in human retinal pigment epithelial cells - Scientific Reports
Scientific Reports - Soft matrix promotes ciliogenesis in human retinal pigment epithelial cells
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Reposted by Ignacio Vega-Vásquez
Matt Lycas @lycasworks.bsky.social · 27/04/2026
www.protocols.io/view/cryo-ex... New protocol alert!! Cryo-expansion microscopy of C. elegans and Tardigrades using the high pressure freezer!
protocols.io
Cryo-Expansion Microscopy of C. elegans and Tardigrades
Cryo-Expansion Microscopy of C. elegans and Tardigrades. Expansion microscopy (ExM) improves imaging r. Read full protocol, steps, and materials on protocols.io
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David Solecki @so-lets-kilab70.bsky.social · 27/11/2025
Thanksgiving update: Turkey’s brined. Pie’s baked. Pickle slice just hit metaphase. Breaks from cutting edge science? Never heard of ’em. Happy Thanksgiving y’all 🥒🔬🦃 #Thanksgiving #CellBiology #NerdHumor #Science
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Sauer Lab @sauer-lab.bsky.social · 19/08/2025
🚨 New Preprint! Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons. ▶️ www.biorxiv.org/content/10.1...
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Ashley Juavinett, PhD @ashleyjuavinett.bsky.social · 22/07/2025
You can join this challenge to try and predict Alzheimer's pathology from transcriptomic data! www.synapse.org/Synapse:syn6... It launches July 27! #hackathon @alleninstitute.org
synapse.org
SEA-AD DREAM Challenge - Predicting Alzheimers Pathology from snRNA-seq Data
'SEA-AD DREAM Challenge - Predicting Alzheimers Pathology from snRNA-seq Data' (Synapse ID: syn66496696) is a project on Synapse. Synapse is a platform for supporting scientific collaborations cen...
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Reposted by Ignacio Vega-Vásquez
Meoow.co @catelovers.bsky.social · 09/12/2024
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Gerti Beliu @beliulab.bsky.social · 27/11/2024
Ready to dive into the world of "Fluorescence Bioimaging"? Here’s our starter pack! 🧪✨ Explore colleagues working on tools, techniques, and tips to illuminate biology at the nanoscale. #Bioimaging #FluorescenceMicroscopy #SuperResolution go.bsky.app/Dns7H6k
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(((Dr Hannah Wirtshafter))) 🔬 @aheadofthenerve.bsky.social · 24/11/2024
🚨 New #Blueprint🚨 Ever wondered how the HPC supports learning across different contexts? My newest, a combo of experimental and comp neuro, w @SaraASolla & @DisterhoftLab, uncovers a 'universal' memory code in the HPC—consistent across animals and environments! 🧵👇 www.biorxiv.org/content/10.1...
biorxiv.org
A universal hippocampal memory code across animals and environments
How learning is affected by context is a fundamental question of neuroscience, as the ability to generalize learning to different contexts is necessary for navigating the world. An example of swift co...
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Reposted by Ignacio Vega-Vásquez
Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 23/11/2024
I just created a Microscopy feed that tracks anything that has a cute 🔬 emoji on it as well as the simple #microscopy and #imaging tags. Enjoy! bsky.app/profile/did:...
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Reposted by Ignacio Vega-Vásquez
Michael Bang Petersen @m-b-petersen.bsky.social · 20/11/2024
A mapping of how Bluesky is becoming the new Scientific Twitter mikeyoungacademy.dk/bluesky-is-e...
mikeyoungacademy.dk
Bluesky is emerging as the new platform for science - Mike Young Academy
Scientific Twitter is about to find its true successor. And it is not X. This, our latest release, shows that the Bluesky network of scientists is growing — and growing.
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Nicolas Chiaruttini @nkiaru.bsky.social · 20/11/2024
Direct streaming of an #OMERO dataset in #BigDataViewer from the public server omero-tim.gerbi-gmb.de (dataset from the Workshop 35). Thank you Tom and @gerbi.bsky.social !
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Reposted by Ignacio Vega-Vásquez
DM to bookmark @bookmarkit.bsky.social · 13/11/2024
Hello, I'm a way to save bookmarks until we get a real bookmarking feature. Just DM me a post by tapping the three dots on the bottom right and selecting 'Send via direct message'. Type my handle (@bookmarkit.bsky.social) to find me and send me the post. You can practice on this post if you like 🔖
Post options menu showing "Send via direct message" as the third option
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Reposted by Ignacio Vega-Vásquez
The PhD Place - Academic Community @thephdplace.bsky.social · 15/11/2024
It took us three years to build up a community on X. Please help us find our community here, too 🤗 #academia
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Reposted by Ignacio Vega-Vásquez
Imaging Neuroscience @imagingneurosci.bsky.social · 16/11/2024
New paper in Imaging Neuroscience by Davood Karimi and Simon K. Warfield: Diffusion MRI with machine learning doi.org/10.1162/imag...
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Reposted by Ignacio Vega-Vásquez
Imaging Neuroscience @imagingneurosci.bsky.social · 17/11/2024
New paper in Imaging Neuroscience by John C. Williams, Jared X. Van Snellenberg, et al: Functional localization of the human auditory and visual thalamus using a thalamic localizer functional magnetic resonance imaging task doi.org/10.1162/imag...
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