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AndreaVentura

@andreaventura.bsky.social
2.2K followers 2.5K following 72 posts

My lab studies the biology and genetics of cancer using a combination of genome editing, biochemical, and computational methods. Opinions are my own (Andrea Ventura) and do not reflect those of my employer. venturalaboratory.com

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AndreaVentura @andreaventura.bsky.social · 25/09/2026
Very nice paper from @agnelsfeir.bsky.social and colleagues on the role of MMEJ in ecDNA maintenance and rearrangements. www.nature.com/articles/s41...
nature.com
MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness - Nature
Stability of extrachromosomal DNA (ecDNA) relies on microhomology-mediated end joining at fragile TA-rich sites, with FANCM suppressing break formation, suggesting that Polθ disruption may destab...
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Graham Erwin @grahamerwin.bsky.social · 18/08/2026
The Baylor College of Medicine Conference on Structural Variants and DNA Repeats is back, and this year it has a new home! Join us in person in Houston November 19th–20th. Or join online. Virtual registration is FREE! ErwinLab.org/svar-conference
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AndreaVentura @andreaventura.bsky.social · 20/03/2026
Celebrating our super postdoc Davide Pradella, who will soon start his own lab. We expect amazing things from him!
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AndreaVentura @andreaventura.bsky.social · 18/03/2026
We are seeking a highly motivated scientist with expertise in mouse embryo manipulation and the generation of genetically engineered mouse models. This is a permanent position with competitive compensation. Contact me via direct message if interested. Please share!
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Acyn @acyn.bsky.social · 06/03/2026
Obama: Every day you wake up to things you just didn’t think were possible. Each day we’re told by those in high office to fear each other. Everywhere we see greed and bigotry being celebrated, and bullying and mockery masquerading as strength.
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Barack Obama @barackobama.bsky.social · 28/01/2026
More and more Americans are voicing their outrage at the tactics being deployed by federal agents in Minnesota. But it’s important to understand the broader implications of what this administration is doing, and the threat it poses to the basic freedoms of every American.
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Bruce Springsteen @brucespringsteen.net · 28/01/2026
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free
youtu.be
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
YouTube video by Bruce Springsteen
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AndreaVentura @andreaventura.bsky.social · 28/01/2026
Brilliant!
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Barack Obama @barackobama.bsky.social · 25/01/2026
The killing of Alex Pretti is a heartbreaking tragedy. It should also be a wake-up call to every American, regardless of party, that many of our core values as a nation are increasingly under assault.
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AndreaVentura @andreaventura.bsky.social · 24/01/2026
Excellent work!
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AndreaVentura @andreaventura.bsky.social · 05/11/2025
“Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.” Winston Curchill
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Gautam Dey @gautamdey.bsky.social · 04/10/2025
If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back. I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support
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AndreaVentura @andreaventura.bsky.social · 04/10/2025
Just visited @ifomresearch.bsky.social in Milan. It was a true pleasure to see the direction this cancer research institute has taken. The energy and the enthusiasm of the faculties was contagious. Plus, Milan is a thriving city. European science at the best.
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AndreaVentura @andreaventura.bsky.social · 05/06/2025
media.tenor.com
a man wearing 3d glasses is holding a bag of popcorn
ALT: a man wearing 3d glasses is holding a bag of popcorn
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Human Technopole @humantechnopole.bsky.social · 22/04/2025
🚨 Fully funded #PhD opportunities at Human Technopole in Milan! 🔬 Apply by 9 June to join top research groups in Comp Bio, Struct Bio, Genomics, Neurogenomics, Mol Cell Bio 🌍 Open to grads worldwide via SEMM 👉 humantechnopole.it/en/news/10-f...
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Josh Marshall @joshtpm.bsky.social · 07/04/2025
You may be fearing your 401k is no longer enough for you to retire. But with all the cuts to NIH and Medicare you also won't live as long. So the policies are integrated.
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Dr. Lucky Tran @luckytran.com · 05/04/2025
100,000+ people marched at the #HandsOff rally in New York!
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AndreaVentura @andreaventura.bsky.social · 04/04/2025
Great opportunity!
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Elisabeth Bik @elisabethbik.bsky.social · 01/04/2025
More than 1,900 scientists write letter in ‘SOS’ over Trump’s attacks on science Members of the National Academies of Sciences, Engineering and Medicine warned Americans of ‘real danger in this moment’ www.theguardian.com/us-news/2025...
theguardian.com
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Igor Ulitsky @igorulitsky.bsky.social · 30/03/2025
I'll be in Boston/NYC/UPenn for <72 hrs this week explaining why Weizmann is the best school there is. If you know anyone that it can be relevant for - please DM me for details.
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 29/03/2025
very much worth reading -- the stakes for the health and safety of all Americans could not be greater
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Kristian Helin @helink.bsky.social · 24/03/2025
....and to be followed by broad investment in science as the columnist suggests. www.theguardian.com/commentisfre...
theguardian.com
A French university is offering ‘scientific asylum’ for US talent. The brain drain has started | Alexander Hurst
The Trump administration is cutting funding, while specifically targeting institutions like Columbia. No wonder academics want out, says Guardian Europe columnist Alexander Hurst
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Peter Andersen @germline.bsky.social · 24/03/2025
⌛📝 One week left to apply to our latest call for faculty positions here at @molbiolau.bsky.social in Aarhus, Denmark 🇩🇰 Two (👀) positions are available w. open topic + rank (tenure-track assist or assoc professorship dep. on career stage). mbg.au.dk/en/news-and-...
mbg.au.dk
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Aria Vaishnavi, PhD @drariav.bsky.social · 10/03/2025
Save the Date! Cancer Molecular Therapeutics Research Association Annual Meeting in Utah July 13-17. Please register today. Incredible line up of speakers: RT! @andreaventura.bsky.social @rjdlab.bsky.social #lcsm
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Lorenzo de la Rica @ldelarica.bsky.social · 24/02/2025
Very excited to share the stellar speaker line-up at our ecDNA conference this June in London! 👇 If you're interested in #ecDNA and want to hear or present groundbreaking research, register now. Abstract submission deadline is 14 March. Learn more: www.cancergrandchallenges.org/ecDNA-2025
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AndreaVentura @andreaventura.bsky.social · 19/02/2025
If you want to learn single-cell analysis from scratch with an user friendly, hands on, approach I very strongly recommend the series of FREE workshops offered by the SAIL team at @mskcancercenter.bsky.social , lead by @ronanchaligne.bsky.social . sail.mskcc.org/computationa...
sail.mskcc.org
Single-cell Data Analysis Workshop – Single-cell Analytics Innovation LabChaligne Lab Website
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AndreaVentura @andreaventura.bsky.social · 27/01/2025
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AndreaVentura @andreaventura.bsky.social · 27/01/2025
🧪 fellow scientists, any advice on a good primer for scRNAseq analysis. Not just the coding part, but the math behind it as well.
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Gaetano Gargiulo @ggargiul.bsky.social · 31/12/2024
In www.biorxiv.org/content/10.1... we propose that #KRAS #dosage integrates signaling & transcription to regulate cell states, driving #heterogeneity, progression & #metastasis
biorxiv.org
Transcriptional Dosage of Oncogenic KRAS Drives Lung Adenocarcinoma Cell States, Progression and Metastasis
Cancer cells display distinct, recurrent phenotypic cell states. Metastatic spreading correlates with tumor cell state evolution. However, the molecular mechanisms underlying metastasis remain elusive...
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AndreaVentura @andreaventura.bsky.social · 30/12/2024
I’m reaching out about a Memorial Sloan Kettering Cancer Center event I’m participating in —Cycle for Survival. Right now, Cycle for Survival has a special year-end match going on — every donation is being doubled!
mskcc.convio.net
Cycle for Survival: The Movement to Beat Rare Cancers
Support rare cancer research at Memorial Sloan Kettering Cancer Center.
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AndreaVentura @andreaventura.bsky.social · 18/12/2024
🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...
nature.com
Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature
Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based&nbsp;approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...
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Lluis Morey @lluismorey.bsky.social · 11/12/2024
Hello to my small Bsky community. We have postdoc positions open to study epigenetic mechanisms contributing to resistance to chemo+immuno in TNBC, and projects related to epigenetic determinants of neurodevelopmental disorders. Feel free to reach out to me here/via email. Please like and repost!
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AndreaVentura @andreaventura.bsky.social · 06/12/2024
Really interesting paper on how aging limits lung cancer progression by the Tammela lab www.nature.com/articles/s41...
nature.com
Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature
Studies using mouse models of lung adenocarcinoma identify an association between age, iron homeostasis and tumour initiation potential that involves NUPR1 and lipocalin-2.
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Ulrike Harjes @ulrikeharjes.bsky.social · 28/11/2024
#NatureMedicine is recruiting! We are looking for an editor to champion the areas of #Metabolism, #Endocrinology and #WomensHealth. Located in NY or Shanghai. Apply by Dec 2nd! Reach out if you have questions. @natureportfolio.bsky.social springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, Nature Medicine (Metabolism, Endocrinology &amp; Women’s Health)
Title: Associate or Senior Editor, Nature Medicine (Metabolism, Endocrinology &amp; Women’s Health) Location(s): New York or Shanghai - Hybrid Working Application Deadline: December 1st 2024 About Spr...
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Anna Obenauf @obenaufa.bsky.social · 27/11/2024
1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...
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AndreaVentura @andreaventura.bsky.social · 26/11/2024
A list of science journals (mostly biomed) to be updated as more join Bluesky go.bsky.app/5kmzyLp
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Amaia Lujambio @amaialujambio.bsky.social · 21/11/2024
Very excited to share our latest publication on the role of NOTCH1 in sexual dimorphism in liver cancer and published in Cancer Discovery! Super proud of Katie Lindblad for leading this study as part of her outstanding PhD work.
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AndreaVentura @andreaventura.bsky.social · 21/11/2024
That's quite impressive. I guess our -20 is their 'room temperature'...
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AndreaVentura @andreaventura.bsky.social · 18/11/2024
I had a ton of fun discussing this famous paper with a group of very enthusiastic and bright Weill-Cornell Medical College students. In my opinion it is one of the most elegant studies ever published. Any suggestion for what we should read next? The class is about logical thinking. #science
General Nature of the genetic code for proteings. Nature paper by Crick,. Barnett, Brenner, and Watts-Tobin
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AndreaVentura @andreaventura.bsky.social · 18/11/2024
Really cool work by Bobby Bowman (UPenn) and Ross Levine (MSK) using next-generation cancer models to study mutations order and dependency in leukemia. www.cell.com/cancer-cell/...
cell.com
In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy
Bowman et al. develop orthogonal DNA recombinase tools to sequentially and reversibly control somatic mutations in leukemic evolution. These approaches identify how mutation timing and order influence...
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Javier Santoyo @jsantoyo.bsky.social · 12/11/2024
Coordinated inheritance of extrachromosomal DNAs in cancer cells. #ExtrachromosomalDNA #ecDNA #CancerCells @natureportfolio.bsky.social www.nature.com/articles/s41...
nature.com
Coordinated inheritance of extrachromosomal DNAs in cancer cells - Nature
Cooperative species of extrachromosomal DNAs are coordinately inherited through mitotic co-segregation.
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Nicolas Robine 🇪🇺🇫🇷🇺🇸 @nicorobine.bsky.social · 09/10/2024
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution. Many years of collaboration between Weill-Cornell's Bishoy Faltas and Olivier Elemento with my group at NYGC. Really proud of this paper! www.nature.com/articles/s41...
nature.com
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution - Nature
Whole-genome sequencing of matched serial tumours from patients identifies two key mutagenic factors (APOBEC3 and chemotherapy)&nbsp;and extrachromosomal DNA-forming structural variants&nbsp;that driv...
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AndreaVentura @andreaventura.bsky.social · 14/11/2024
Interesting perspective by S Quake out in Cell www.cell.com/cell/fulltex...
cell.com
The cellular dogma
In this essay, I will put forth what I see as a major conceptual challenge for biology in the next decade, one that is inspired by Crick’s Central Dogma: understanding information flow in the cell in ...
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Alper Akay @alperakay.bsky.social · 14/11/2024
We are advertising two PhD positions in our lab on RNA splicing and modifications in development and cancer. NRPDTP project is open to international applicants. UEA project is for UK applicants only. With Yiliang Ding and Mark Williams www.findaphd.com/phds/?Keywor...
findaphd.com
akay PhD Projects, Programmes & Scholarships
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in akay. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
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Ozren Bogdanovic @obog.bsky.social · 14/11/2024
We have 15 PhD positions available as part of the DANIO-ReCODE MSCA DN 🇪🇸🇩🇪🇸🇮🇭🇷🇦🇹🇬🇧 Great opportunity for anyone interested in developmental biology, regeneration, genomics, and computational sciences. For project descriptions and how to apply, check: euraxess.ec.europa.eu/jobs/290548
euraxess.ec.europa.eu
15 PhD positions in Decoding Transcriptional Regulation in Regeneration by Advanced Genomics and Computational tools (funded by the DANIO-ReCODE MSCA 2023 Doctoral Network)
The principal objective of DANIO-ReCODE is to provide world-class doctoral training to a new generation of early-career researchers interested in understanding the complex and multilayered process of ...
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Katja Röper @katjaroeper.bsky.social · 14/11/2024
Postdoc position available in the Röper lab at the University of Cambridge @PDN_Cambridge! Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids! jobs.cam.ac.uk/job/48947/
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Ya’el Courtney, PhD @scienceyael.bsky.social · 12/11/2024
The @HHMINEWS Gilliam Fellowship applications are due in ~3 weeks! If you're a 2nd or 3rd yr PhD student (& U.S. citizen) passionate about science & building an inclusive scientific community, check out my application guide! 🌐🔬 #HHMIGilliam www.yaelcourtney.com/resources-an...
yaelcourtney.com
Navigating the HHMI Gilliam Fellowship Application — Ya'el Courtney
HHMI Gilliam Fellowship Application Advice
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AndreaVentura @andreaventura.bsky.social · 14/11/2024
Interested in gene amplification, cancer, and ecDNAs? This is the conference for you. London, June 2025. Will be fun! www.cancergrandchallenges.org/ecDNA-2025
cancergrandchallenges.org
Cancer Grand Challenges Conference: extrachromosomal DNA
Taking place on 11 - 13 June 2025 in London, UK. Registration is now open.
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AndreaVentura @andreaventura.bsky.social · 14/11/2024
@jung-sillah.bsky.social hi! Can I join the cancer bio starter pack as well? Thanks for organizing this.
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AndreaVentura @andreaventura.bsky.social · 14/11/2024
First post here. Our lab at MSKCC studies how #cancer form. Hoping for a vibrant and safe place to talk #science, connect with fellow #scientists, and inform the public about science and rationality. Interested in #genome_editing, #ecDNAs, #non-coding RNAs, and #cancer_biology
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