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Guy Leonard

@guyleonard.eurosky.social
913 followers 1.8K following 364 posts

Bioinformatician w/ Tom Richards & Team at @oxfordbiology.bsky.social Homebrewer. WSET Beer Level 2. Rejoiner 🇪🇺🤝🇬🇧 AI is not 'inevitable', resist its uncritical adoption. I unfollow everyone who hypes/uses genAI/LLMs/agentic coding.

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Reposted by Guy Leonard
Sarah T Roberts, PhD @ubiquity75.xyz · 13/06/2026
The goal isn’t to replace the work of humans. It’s to make a case for its devaluation.
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Guy Leonard @guyleonard.eurosky.social · 29/09/2026
I just signed a petition to stop the rollout of facial recognition surveillance in the UK. The Government and shops are scanning us without clear laws in place, using our faces like barcodes. It is really invasive. Can you take 30 seconds to sign it too? you.38degrees.org.uk/petitions/st...
you.38degrees.org.uk
Stop scanning us all with facial recognition!
I just signed a petition to stop the massive rollout of facial recognition surveillance in the UK. The government and shops are starting to scan us without clear laws in place, effectively turning our...
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Reposted by Guy Leonard
Velour Shirt @object.works · 29/09/2026
This is a metaphor for so many things these days that I couldn't choose
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the babahuck @tylerhuckabee.bsky.social · 28/09/2026
bad news babe a rogue openai agent must have hacked our refrigerator last night and drank 15 beers
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Iñaki Ruiz-Trillo @multicellgenome.bsky.social · 28/09/2026
We have a new branch in the family tree of animals: Atreyea- a previously unrecognized lineage among the closest unicell relatives of animals. Led by @konsmitsi.bsky.social & @freejakoba.bsky.social together with a fantastic team of collaborators. 🔗 papers.ssrn.com/sol3/papers.... #protistsOnSky
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Guy Leonard @guyleonard.eurosky.social · 28/09/2026
The plagiarism nexus strikes again. Stop feeding the slop machine your precious data.
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Julia Van Etten @couchmicroscopy.bsky.social · 26/09/2026
Protists deserve the spotlight and so do scientists! This was such an honor but mostly, this project reminded me why I have the best job and friends/colleagues in the world! 🔬
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MwahahahahahadScientist @mads100tist.bsky.social · 25/09/2026
This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪
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Reposted by Guy Leonard
Joe Hanly @hanliconius.bsky.social · 22/09/2026
I hate to do this with real data, but this is a persistent data vis issue in chromosome synteny riparian plots that we Need to get better at. Left, a synteny plot published today. Right, a rearranged version with exactly the same gross arrangement but with reordered chromosomes:
chromosome synteny riparian plot in which every chromosome has crossing lineschromosome synteny plot in which no chromosomes have crossing lines. The underlying structure is identical.
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Iva Vukušić @vukusiciva.bsky.social · 21/09/2026
This ridiculous number of applications is, in my view, the result of 2 nightmare developments happening concurrently 1.the precariousness of the job market for young PhD graduates which then fuels further: 2.the AI tools enabling overproduction of proposals. #Research #ERC #ResearchFunding #Academia
Just a screenshot with an EU logo saying that the 2026 call has attracted considerable interest from the research community with 21,627 applications submitted.
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Reposted by Guy Leonard
Nina Markl 🏳️‍⚧️🏳️‍🌈 @ninamarkl.bsky.social · 21/09/2026
LLM chatbots on published papers without explicit opt-in from authors is so incredibly disrespectful and completely undermines the idea of a published version of record
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Bethany Black @bethanyblack.bsky.social · 17/09/2026
I really need journalists to learn that every time OpenAI or Anthropic or xAI says that their model has broken containment and could destroy humanity that it’s a marketing pitch by companies running out of cash with high overheads and no profitable business model wanting more investment.
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Guy Leonard @guyleonard.eurosky.social · 16/09/2026
Season 8 of Game of Thrones is now not the most embarrassing part of the series, since Ed-Sh**ren appears in S07E01. Well, it was embarrassing before, but now it is this worst mistake the show runners ever made.
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Reposted by Guy Leonard
Rob Patro @robp.bsky.social · 16/09/2026
New preprint led by Zoe Rudnick: bramble 🌿 RNA-seq quantification makes you pick a side. Align to the transcriptome and your quantifier is happy, but reads from unannotated transcripts get misassigned to annotated ones. Align to the genome and you keep discovery, but limit quantification choices.
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Laura Hadland @morrighani.bsky.social · 15/09/2026
More anti-AI breweries, pubs and cidermakers have been added to my directory. And before anyone comments, if you don't care that a business uses AI, then don't bother reading the list. Easy.
extremehousewife.com
Ethical and Sustainable Brewery Directory
A directory of ethical and sustainable brewery businesses in the UK who putting the environment, their community and their teams first.
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Twonks @twonks.bsky.social · 14/09/2026
Wow
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Thomas Mock @thomasmock.bsky.social · 01/09/2026
On behalf of 108 colleagues and friends from 11 countries, thrilled to share the first paper from our 100 #Diatom Genomes Project (100DGP). Just out @plosbiology.org | @norwichmicro.bsky.social | @ueaenv.bsky.social | @jgi.doe.gov doi.org/10.1371/jour...
doi.org
The 100 Diatom Genomes Project
This Community Page presents the 100 Diatom Genomes Project, which aims to sequence the genomes and transcriptomes of 100 diatom species across major lineages, life forms and ecological strategies. Th...
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University of Bristol Biological Sciences @bristolbiosci.bsky.social · 09/09/2026
We are hiring a new lecturer in Bioinformatics! Hit the link below to find out more and apply: www.bristol.ac.uk/jobs/find/de... #bristoluni #wearebristoluni #biologicalsciences
Job Alert! Lecturer in Bioinformatics. Come and join use in the world class Life Sciences Building at the University of Bristol! Closing date: Sunday 27 September.
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
The extraordinary diversity, biology and complexity of #protists pose significant challenges to the #genomics community. That’s why a new collaboration will look to address some of the major technical barriers for sequencing protists from bulk cultures and the environment.
earlham.ac.uk
Major investment to unlock the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and en...
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Julie Boisard @protistsforthewin.bsky.social · 14/09/2026
CoMR is now published in Briefings in Bioinformatics and available on github github.com/theLabUpstai... #protistsonsky doi.org/10.1093/bib/...
doi.org
CoMR: an integrative scoring pipeline for comprehensive mitochondrial proteome reconstruction across eukaryotes
Abstract. Mitochondrial proteome reconstruction from eukaryotic sequence data typically relies on prediction of mitochondrial targeting signals (MTSs). How
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Guy Leonard @guyleonard.eurosky.social · 11/09/2026
If food prices had risen as fast as rents since 1988, a 10-item shop would be 5x more expensive than it currently is. Ask the new Housing Secretary to slam the brakes on soaring rents with a real printed postcard I paid for 3 so you can send two free. costofrenting.generationrent.justpost.cards
costofrenting.generationrent.justpost.cards
The Cost of Renting Receipt
Send a real, printed postcode which combines a call to action and your personal experience, is a really effective way to get through to the new Housing Secretary who has the power to tackle unaffordab...
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Guy Leonard @guyleonard.eurosky.social · 10/09/2026
So they can have 15% of their salary removed then. 🤷
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Reposted by Guy Leonard
Genome Biology and Evolution @genomebiolevol.bsky.social · 10/09/2026
@guyleonard.eurosky.social @brockhurstlab.bsky.social et al. report a T2T genome for Micractinium conductrix, an endosymbiont of Paramecium bursaria, publishing one of the most complete Chlorellaceae algal genome assemblies to date 🔗 academic.oup.com/gbe/article/... #societyjournal #genome #algae
academic.oup.com
De Novo Genome Sequence Assembly of the Algal Endosymbiont Micractinium conductrix Derived From Its Host Paramecium bursaria 186b
Abstract. Endosymbiosis is a major driver of evolutionary innovation and underpins the function of diverse ecosystems. The origins and evolution of endosym
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Guy Leonard @guyleonard.eurosky.social · 10/09/2026
Guillermo del Toro on AI: "...your intelligence ends at the question. You don't seek the answer. It's given to you." I think that is the most succinct and clear rejection of genAI you will ever read.
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Guy Leonard @guyleonard.eurosky.social · 09/09/2026
I went to see Star Trek IV: The Voyage Home last night as part of its 40th anniversary and Trek's 60th. It was very cool to see it on the big screen! Now I really need LEGO to make a Bird of Prey version ASAP!
A Klingon Bird of Prey hovers over a whaling ship in the ocean. A scene from Star Trek IV.
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Guy Leonard @guyleonard.eurosky.social · 09/09/2026
When the director of the National Treasure movie series announced a third movie was in the works, little did they know Nicolas Cage was going to do the special effects himself!
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Guy Leonard @guyleonard.eurosky.social · 09/09/2026
The queue as of 9am for Dune Pt3 at the BFI IMAX in London. This has got to be all bots surely?
Your queued number is 36157. For dune pt 3 at the BFI IMAX
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Guy Leonard @guyleonard.eurosky.social · 08/09/2026
More in luxury surveillance: www.notebookcheck.net/LG-smart-TVs... It's not just your TV; your laptop screen, your USB-C monitor, your phone. They are all doing this. The LG TV even looks for open WiFi networks without you knowing to upload data.
notebookcheck.net
LG smart TVs caught logging audio with screen off and snooping on local devices
An investigation by Gamers Nexus found LG smart TVs sweep local networks to map phones and nearby devices. Tests also showed the sets can capture microphone audio with the screen off — they then uploa...
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Reposted by Guy Leonard
Humanists UK @humanists.uk · 08/09/2026
We work to better ourselves and the rest of humanist. Captain Picard. Star Trek: First Contacts, 1996
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Joe Keating @evopalaeo.bsky.social · 07/09/2026
⚠️BIOINFORMATCIS JOB ALERT⚠️ Come and join us @bristolbiosci.bsky.social We are recruiting a Lecturer in Bioinformatics. Details here: www.bristol.ac.uk/jobs/find/de... Please feel free to get in touch if you are interested!
bristol.ac.uk
Details | Working at Bristol | University of Bristol
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Olivia Guest · Ολίβια Γκεστ @olivia.science · 13/06/2026
2) industry buys people out a great deal and conflicts of interest are often not properly displayed. Many already have started rebranding as AI literacy and even critical AI literacy "experts" — what's critical about having a conflict of interest you hid? bsky.app/profile/oliv... 2/
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Luis Javier Galindo @luisjagago.bsky.social · 04/09/2026
I am extremely happy to announce that I have been awarded an @erc.europa.eu ERC Starting Grant to lead the ProtistEye project! We will be diving into the function, architecture, and diversity of eye-like structures across different protists to better understand their evolution. Stay tuned for more!
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Olivia Guest · Ολίβια Γκεστ @olivia.science · 10/10/2025
important on LLMs for academics: 1️⃣ LLMs are usefully seen as lossy content-addressable systems 2️⃣ we can't automatically detect plagiarism 3️⃣ LLMs automate plagiarism & paper mills 4️⃣ we must protect literature from pollution 5️⃣ LLM use is a CoI 6️⃣ prompts do not cause output in authorial sense
5 Ghostwriter in the Machine
A unique selling point of these systems is conversing and writing in a human-like way. This is imminently understandable, although wrong-headed, when one realises these are systems that
essentially function as lossy2
content-addressable memory: when
input is given, the output generated by the model is text that
stochastically matches the input text. The reason text at the output looks novel is because by design the AI product performs
an automated version of what is known as mosaic or patchwork
plagiarism (Baždarić, 2013) — due to the nature of input masking and next token prediction, the output essentially uses similar words in similar orders to what it has been exposed to. This
makes the automated flagging of plagiarism unlikely, which is
also true when students or colleagues perform this type of copypaste and then thesaurus trick, and true when so-called AI plagiarism detectors falsely claim to detect AI-produced text (Edwards, 2023a). This aspect of LLM-based AI products can be
seen as an automation of plagiarism and especially of the research paper mill (Guest, 2025; Guest, Suarez, et al., 2025; van
Rooij, 2022): the “churn[ing] out [of] fake or poor-quality journal papers” (Sanderson, 2024; Committee on Publication Ethics,Either way, even if
the courts decide in the favour of companies, we should not allow
these companies with vested interests to write our papers (Fisher
et al., 2025), or to filter what we include in our papers. Because
it is not the case that we only operate based on legal precedents,
but also on our own ethical values and scientific integrity codes
(ALLEA, 2023; KNAW et al., 2018), and we have a direct duty to
protect, as with previous crises and in general, the literature from
pollution. In other words, the same issues as in previous sections
play out here, where essentially now every paper produced using
chatbot output must declare a conflict of interest, since the output text can be biased in subtle or direct ways by the company
who owns the bot (see Table 2).
Seen in the right light — AI products understood as contentaddressable systems — we see that framing the user, the academic
in this case, as the creator of the bot’s output is misplaced. The
input does not cause the output in an authorial sense, much like
input to a library search engine does not cause relevant articles
and books to be written (Guest, 2025). The respective authors
wrote those, not the search query!
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Olivia Guest · Ολίβια Γκεστ @olivia.science · 09/07/2026
you 👏🏼 cannot 👏🏼 automatically 👏🏼 detect 👏🏼 plagiarism > the available detection tools are neither accurate nor reliable and have a main bias towards classifying the output as human-written rather than detecting AI-generated text link.springer.com/article/10.1... 1/
link.springer.com
Testing of detection tools for AI-generated text - International Journal for Educational Integrity
Recent advances in generative pre-trained transformer large language models have emphasised the potential risks of unfair use of artificial intelligence (AI) generated content in an academic environme...
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Guy Leonard @guyleonard.eurosky.social · 02/09/2026
Every time I get an email from BFI IMAX my heart skips a little. Could it be more DUNE 3 tickets today!? Ooooh? Nope. Dammit. (Why has the USA got so many ticket sales and the UK so few. Sigh).
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Katharina Hoff @katharinahoff.bsky.social · 31/08/2026
github.com/Gaius-August...
github.com
GitHub - Gaius-Augustus/Vipsania: Unsupervised Deep Gene Finding
Unsupervised Deep Gene Finding. Contribute to Gaius-Augustus/Vipsania development by creating an account on GitHub.
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Jo Kibble (Political Animal) @politicanimal.bsky.social · 27/08/2026
Most British thing ever is for the day it becomes legal to fit solar extremely easily to your home is the day the sun finally disappears after three months.
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King Mob @kingmob.bsky.social · 25/08/2026
Here's a mod list if you want to keep them out of your feeds: bsky.app/profile/did:...
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Guy Leonard @guyleonard.eurosky.social · 26/08/2026
The Shrinking Landscape of Linguistic Diversity in the Age of Large Language Models. Dehghani et al. arxiv.org/abs/2502.11266 "LLMs...homogenize writing styles, reducing writing-complexity variance by a statistically significant 21-50%...emphasizing conformity over individuality."
arxiv.org
The Shrinking Landscape of Linguistic Diversity in the Age of Large Language Models
Language is far more than a communication tool; it encodes a wealth of information about a person's identity, psychological state, and social context, providing valuable insights for diverse fields in...
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Guy Leonard @guyleonard.eurosky.social · 26/08/2026
I signed! Maybe others will consider it too. I remember signing similar ones back in 2005 too. :/
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Alex Prichard @profalexp.bsky.social · 26/08/2026
A thread on the dispute at Exeter Uni. #ucu #defendexeteruni @ucu.org.uk On 15 June HR called Exeter UCU into a confidential meeting and informed us they would be putting over 500 colleagues at risk of redundancy and expected to loose around 200 staff. The number of c.150 you’ll have seen is FTE.
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Zen Faulkes @doctorzen.net · 26/08/2026
You have probably seem a viral post or two or even a few that show AI slop figures. The "rat dck". The autism bicycle. There are SO MANY MORE that didn't go viral. I'm collecting them all: bit.ly/academic-slop Seven new entries this week.
bit.ly
Pulled From the Trough: Slop Images in Academic Journals
This project collects images created using generative artificial intelligence (gen AI) that have appeared in academic journals and books..If you run across examples of gen AI images in journals or books - whether figures, graphical abstract, covers, or other - please submit it using this form: https://bit.ly/JournalSlopVersion historyVersion 1.0: Released 18 December 2025. Nine entries.Version 2.0: Released 5 January 2026. Four new entries; clickable hyperlinks added to URLs; other minor changes.Version 3.0: Released 31 March 2026. One new entry.Version 2.0: 1 May 2026. Due to erroneous file upload, rollback to previous version until such time as the correct file can be repaired and uploaded.Version 4.0: Released 15 May 2026. Two new entries.Version 5.0: Released 2 June 2026. One new entry.Version 6.0: Released 15 June 2026. One new entry.Version 7.0. Released 17 June 2026. One new entry.Version 8.0: Released 18 June 2026. Two new entries; minor edits; typesetting improvements (real italics and bold type!).Version 8.1: Released 19 June 2026. Hyperlinks fixed.Version 9.0: Released 4 July 2026. One new entry.Version 10.0: Released 12 July 2026. One new entry.Version 11.0: Released 27 July 2026. One new entry.Version 12: Released 2 August 2026. Ten new entries.Version 13: Released 13 August 2026. Eight new entries.Version 14: Released 17 August 2026. Four new entries.Version 15: Released 24 August 2026. Seven new entries.
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 26/08/2026
If some of you are still wondering why we screen randomly purchased antibodies in ExM? Well, cuz we randomely find antibodies labelling key organelles and structures across many species...
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Guy Leonard @guyleonard.eurosky.social · 20/08/2026
All good thing must come to an end... #evomics
Evomics workshops are no longer running.
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Guy Leonard @guyleonard.eurosky.social · 20/08/2026
All good thing must come to an end... #evomics
Evomics workshops are no longer running.
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Elin Videvall @elinvidevall.bsky.social · 18/08/2026
Maureen O'Malley gives a great and thought-provoking keynote titled 'Ecology versus medicine in microbiome research'. #ISME20
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Emanuel Maiberg @emanuelmaiberg.bsky.social · 17/08/2026
We put a tracking device in a shipment of rare books acquired by an anonymous buyer. It ended up at an Amazon facility where the company scans books for training data and destroys them in the process: www.404media.co/we-tracked-a...
404media.co
We Tracked a Shipment of Rare Books. It Ended at an Amazon AI Training Facility
We placed a tracking device in a shipment of rare books to see which AI company was buying it, and found an Amazon facility where Amazon scans and destroys books.
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Dwayne Monroe @cloudquistador.eurosky.social · 15/08/2026
Note what's on display in this clip: the convergence of careerism and supremacist thinking and action. This is common (and what is found in the history of the Third Reich and US history and current conditions). The fascist is not impressed by, and resents their targets' achievements.
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Guy Leonard @guyleonard.eurosky.social · 07/08/2026
Never liked Adam Rutherford, saw him talk at Oxford and he comes off as an arrogant arse. The fact he slimed his way into The Infinite Monkey Cage series, after Robin Ince had to resign, is another reason not to listen.
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