Background : The growing availability of large prokaryotic genomic datasets presents an opportunity to discover new metabolic pathways and enzymatic reactions useful for industrial or synthetic…

Join us for an engaging discussion about one of the most exciting new developments in scholarly publishing in decades! The scholarly publishing system is under intense pressure. Researchers face in…

In LIFE UNBOUNDED, pioneering evolutionary biologist William C. Ratcliff reveals that every great leap in life’s complexity, from the first cells to human culture, was driven by the same underlying pr...

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The Selfish Gene continues to challenge readers half a century later

Genome-wide selective sweeps commonly occur in the human gut microbiome and can spread across the world within decades to produce epidemic-like population structures.

This postdoctoral research position is part of a Cystic Fibrosis Canada Early Career Investigator Award funded for 3-years led by Dr. Fabrice Jean-Pierre and Dr. Fiona Whelan. The aim of this project is to identify the genetic changes that arise in the Pseudomonas aeruginosa genome following perturbations – such as antibiotic treatment – in an in vitro system. The PDRA will use a large dataset of P. aeruginosa genomes and experimental metadata to predict key mutationsto the organism.

Interactive exploration of large phylogenetic trees

Abstract. Understanding the drivers and consequences of horizontal gene transfer (HGT) is a key goal of microbial evolution research. Although co-occurring

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

Nature Communications - It is commonly thought that bacterial species borders tend to be fuzzy, due to frequent exchange of DNA. Here, Diop et al. quantify the patterns of gene flow between core...

Replication Research is a diamond open-access and researcher-led journal that publishes reproductions, replications, and conceptual articles on repetitive research

Today, the next instalment in a short series inspired by bad papers I’ve read (some of them, I have to admit, my own). I’ve let myself rant about what a Methods sections shouldn’t be, and what a Re…

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We present a reference genome assembly from an individual male Violet Carpenter Bee (Xylocopa violacea, Linnaeus 1758). The assembly is 1.02 gigabases in span. 48% of the assembly is scaffolded into…

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The root of the eukaryote Tree of Life is estimated from a new, larger dataset of mitochondrial proteins including all known eukaryotic supergroups, showing it lies between two multi-supergroup assemb...

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Abstract. Homologous recombination is a key evolutionary force that varies considerably across bacterial species. However, how the landscape of homologous

Fekete et al. (2024) generated a chromosome-level reference genome assembly for the mountain hare (Lepus timidus). This represents a significant advancement in genomic research for non-model…

AbstractMotivation. Much of prokaryotic comparative genomics currently relies on two critical computational tasks: pangenome inference and core genome infe

Do you run a journal club? The non-profit, scientist-driven ASAPbio (Accelerating Science and Publication in Biology) promotes transparency and innovation in life science communication, and they are offering funding to organise preprint review clubs. Find out about their other activities, too.

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Postdoc position: amino acid substitution models A postdoc position is available with PI Joanna Masel (https://www.masellab.org/) at the University of Arizona in Tucson. Tucson is a vibrant city of n...