Background : The growing availability of large prokaryotic genomic datasets presents an opportunity to discover new metabolic pathways and enzymatic reactions useful for industrial or synthetic…

Join us for an engaging discussion about one of the most exciting new developments in scholarly publishing in decades! The scholarly publishing system is under intense pressure. Researchers face in…

In LIFE UNBOUNDED, pioneering evolutionary biologist William C. Ratcliff reveals that every great leap in life’s complexity, from the first cells to human culture, was driven by the same underlying pr...

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The Selfish Gene continues to challenge readers half a century later

Genome-wide selective sweeps commonly occur in the human gut microbiome and can spread across the world within decades to produce epidemic-like population structures.

This postdoctoral research position is part of a Cystic Fibrosis Canada Early Career Investigator Award funded for 3-years led by Dr. Fabrice Jean-Pierre and Dr. Fiona Whelan. The aim of this project is to identify the genetic changes that arise in the Pseudomonas aeruginosa genome following perturbations – such as antibiotic treatment – in an in vitro system. The PDRA will use a large dataset of P. aeruginosa genomes and experimental metadata to predict key mutationsto the organism.

Interactive exploration of large phylogenetic trees

Abstract. Understanding the drivers and consequences of horizontal gene transfer (HGT) is a key goal of microbial evolution research. Although co-occurring

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

Nature Communications - It is commonly thought that bacterial species borders tend to be fuzzy, due to frequent exchange of DNA. Here, Diop et al. quantify the patterns of gene flow between core...

Replication Research is a diamond open-access and researcher-led journal that publishes reproductions, replications, and conceptual articles on repetitive research

Today, the next instalment in a short series inspired by bad papers I’ve read (some of them, I have to admit, my own). I’ve let myself rant about what a Methods sections shouldn’t be, and what a Re…

a poem

We present a reference genome assembly from an individual male Violet Carpenter Bee (Xylocopa violacea, Linnaeus 1758). The assembly is 1.02 gigabases in span. 48% of the assembly is scaffolded into…

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The authors analyse 8,790 prokaryotic pangenomes to identify the ecological variables associated with recent versus old horizontal gene transfer events, finding that gene transfers are more common amo...

The authors analyse 8,790 prokaryotic pangenomes to identify the ecological variables associated with recent versus old horizontal gene transfer events, finding that gene transfers are more common amo...

The root of the eukaryote Tree of Life is estimated from a new, larger dataset of mitochondrial proteins including all known eukaryotic supergroups, showing it lies between two multi-supergroup assemb...

openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

Abstract. Homologous recombination is a key evolutionary force that varies considerably across bacterial species. However, how the landscape of homologous

Fekete et al. (2024) generated a chromosome-level reference genome assembly for the mountain hare (Lepus timidus). This represents a significant advancement in genomic research for non-model…