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Vijini Mallawaarachchi

@vijinim.bsky.social
113 followers 121 following 37 posts

Research Fellow @ Flinders University | #Bioinformatics, #Algorithms and #Metagenomics 🧬🦠 | Blog at vijini.medium.com

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Vijini Mallawaarachchi @vijinim.bsky.social · 18/08/2026
@gbouras13.bsky.social talking about his new protein structure-based bacterial genome annotation tool, Baktfold. 🧫🧬 GitHub: github.com/gbouras13/ba... Preprint: www.biorxiv.org/content/10.6... #ISME20
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Vijini Mallawaarachchi @vijinim.bsky.social · 18/08/2026
Such a fantastic talk by Prof Maureen O’Malley about medicine and ecology in microbiome research. 🩺🦠 #ISME20
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Rob Edwards @linsalrob.bsky.social · 17/08/2026
We're having fun developing post-cloud bioinformatics tools: reimagining some of the bioinformatics canon as local, browser-native applications so your data never has to leave your laptop. Here's the first set: edwards.flinders.edu.au/viz/ Let us know if you want other tools local to your laptop
edwards.flinders.edu.au
-viz
Welcome to the -viz suite of tools: classic bioinformatics tools, reimagined for the browser. agviz · bamviz · genbankviz · phispyviz Each of our tools is a classic bioinformatics tool, but reimagi…
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Vijini Mallawaarachchi @vijinim.bsky.social · 17/08/2026
Excited to be talking about my #phage #bioinformatics tool #Phables to study #viral #ecology in #IBD-associated #metagenomes. Come check out my talk in session AS13 at 2.30pm on Tuesday 18th Aug in room 303-305. #ISME20 GitHub: github.com/Vini2/phables Publication: academic.oup.com/bioinformati...
github.com
GitHub - Vini2/phables: 🫧🧬 From fragmented assemblies to high-quality bacteriophage genomes
🫧🧬 From fragmented assemblies to high-quality bacteriophage genomes - Vini2/phables
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Vijini Mallawaarachchi @vijinim.bsky.social · 17/08/2026
Prof Rob Edwards talking about the use of AI to learn from Cystic Fibrosis metagenomic data. #ISME20 @linsalrob.bsky.social
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Vijini Mallawaarachchi @vijinim.bsky.social · 16/08/2026
Starting off Monday with a keynote by Prof Wanda Markotter talking about one health and microbes 🩺🦠 #ISME20
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Vijini Mallawaarachchi @vijinim.bsky.social · 16/08/2026
Excited to be attending my first ever ISME conference 🤩 #ISME20 @isme-microbes.bsky.social
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George Bouras @gbouras13.bsky.social · 07/08/2026
If you are looking for web-based phage annotation, phage-annotation.org is live. Upload a genome to run Pharokka, Phold and Phynteny sequentially (see our recent protocols paper doi.org/10.1002/cpz1...). If you have feedback, please reach out Thanks to @ardc.edu.au for making this possible!
phage-annotation.org
Phage Annotation Server -- phage genome annotation
Free automated phage genome annotation -- pharokka, phold and phynteny in one pipeline.
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Vijini Mallawaarachchi @vijinim.bsky.social · 26/07/2026
🚀 MetaCoAG v1.3.0 is out! This release adds faster FASTA processing, NumPy feature storage, better multiprocessing, cleaner graph traversal, and resumable runs. Benchmarks show up to 28.7x faster runtime and up to 56% lower peak memory. (1/n) #bioinformatics #metagenomics #assemblygraph
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Vijini Mallawaarachchi @vijinim.bsky.social · 18/06/2026
🎤 Very excited to be speaking at #GenomeInformatics26, UK from 2–4 December 2026. 🧬 📢 If you’re working in genome informatics or related areas, submit an abstract by 5 October 2026. Early bird registrations close on 7 September. 😃 #Bioinformatics #ComputationalBiology #Genomics #GenomeInformatics
coursesandconferences.wellcomeconnectingscience.org
Genome Informatics — 20261202
Methods for analysis of large data sets
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Rob Edwards @linsalrob.bsky.social · 02/06/2026
If you do any work with DNA sequencing at some point, you need to assemble the reads. Usually, we just use the contigs, but that ignores important evidence from your data, so @vijinim.bsky.social wrote agtools to explore the assembly graph and learn more! academic.oup.com/bioinformati...
academic.oup.com
agtools: a software framework to manipulate assembly graphs
AbstractMotivation. Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap info
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Susie Grigson @susiegriggo.bsky.social · 26/05/2026
New preprint! 🚨 Phage proteins don't act alone. Phages rely on homooligomerisation to assemble identical protein subunits into functional forms. But figuring out those exact configurations experimentally is tough. Learn about our approach in our new preprint! 👇 (1/n) www.biorxiv.org/content/10.6...
biorxiv.org
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Vijini Mallawaarachchi @vijinim.bsky.social · 08/05/2026
🎉 Excited to share that our paper, “agtools: A Software Framework to Manipulate Assembly Graphs”, has been accepted in Bioinformatics Advances. (1/n) 🔗 GitHub: github.com/Vini2/agtools 📄 Paper: academic.oup.com/bioinformati... #bioinformatics #genomics #openscience
academic.oup.com
agtools: A Software Framework to Manipulate Assembly Graphs
AbstractMotivation. Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap info
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Vijini Mallawaarachchi @vijinim.bsky.social · 21/04/2026
🚀 Humbled to hit 1,000 citations on Google Scholar. Thank you to all the people who contributed, read, cited, challenged, and built on this work. #research #milestones #science scholar.google.com/citations?us...
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George Bouras @gbouras13.bsky.social · 14/01/2026
Phold's manuscript is now available @narjournal.bsky.social thanks to @susiegriggo.bsky.social @npbhavya.bsky.social @vijinim.bsky.social @linsalrob.bsky.social @martinsteinegger.bsky.social @milot.bsky.social @eunbelivable.bsky.social & others not on bsky #phagesky academic.oup.com/nar/article/...
academic.oup.com
Protein structure-informed bacteriophage genome annotation with Phold
Abstract. Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents.
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Vijini Mallawaarachchi @vijinim.bsky.social · 02/12/2025
🚀 Just launched: GraphBin Visualise (WASM) a browser-based visualisation tool for comparing initial metagenomic binning results vs refined results from GraphBin - all running in your browser, no backend required. (1/n) #bioinformatics #metagenomics #binning #webapp #pyiodide #webassembly
github.com
GitHub - metagentools/graphbin-visualise-wasm-app: GraphBin Visualise WebAssembly App
GraphBin Visualise WebAssembly App. Contribute to metagentools/graphbin-visualise-wasm-app development by creating an account on GitHub.
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Vijini Mallawaarachchi @vijinim.bsky.social · 28/11/2025
This package to decompose weighted graphs into weighted paths by @alextomescu.bsky.social is going to be very useful. Can't wait to try it out in my viral metagenomic tools. 🤩🧬🖥️ #bioinformatics #graphs #graph-algorithms #flow-decomposition #integer-linear-programming github.com/algbio/flowp...
github.com
GitHub - algbio/flowpaths: A Python package to quickly decompose weighted graphs (acyclic or not) into weighted paths or walks, under various models.
A Python package to quickly decompose weighted graphs (acyclic or not) into weighted paths or walks, under various models. - algbio/flowpaths
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Rob Edwards @linsalrob.bsky.social · 26/11/2025
Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years #phagesky www.nature.com/articles/s41...
nature.com
Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–...
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Jimmy Breen @wessidepraxis.bsky.social · 26/11/2025
Thanks to the amazing Adelaide Bioinformatics community for making #ABACBS2025 an amazing event. We couldn’t have done it without you. A few more days of workshops to go before the festival finishes for another year 😀
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Hasindu Gamaarachchi @hasindu2008.bsky.social · 26/11/2025
Congratulations Hiruna Samarakoon (yet to be on bluesky) for winning the #abacbs2025 “Torsten Seemann” Outstanding Bioinformatics Software Developer Award!!! 🎉🎉🎉
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Anuradha Wickramarachchi @anuradhawick.bsky.social · 26/11/2025
It was great to present TRECA at ABACBS 2025 as a lightening talk. Come find my poster #21. #ABACBS2025 @abacbs.bsky.social
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Vijini Mallawaarachchi @vijinim.bsky.social · 26/11/2025
iplotx by Fabio Zanini supports visualising any network or tree analysis library. Can’t wait to visualise assembly graphs with iplotx! 🤩💻 #ABACBS2025 @abacbs.bsky.social
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Vijini Mallawaarachchi @vijinim.bsky.social · 26/11/2025
@rrwick.bsky.social solving all of our problems in long-read bacterial genome assembly with Autocycler. 😃🧬🦠 #ABACBS2025
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Vijini Mallawaarachchi @vijinim.bsky.social · 25/11/2025
🧬 Come check out my poster on agtools, an open-source Python framework for analysing and manipulating assembly graphs at #ABACBS2025 Poster #106 • 💻 Github: github.com/Vini2/agtools 📄 Preprint: biorxiv.org/content/10.110…
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George Bouras @gbouras13.bsky.social · 25/11/2025
A gymnastic start to day 2 with a keynote from Ami Bhatt #ABACBS2025
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Hasindu Gamaarachchi @hasindu2008.bsky.social · 25/11/2025
Thanks mate Off the press just couple of hours before the talk www.nature.com/articles/s41...
nature.com
Targeted sequencing and iterative assembly of near-complete genomes - Nature Communications
Long-read sequencing enables high-quality genome assemblies, but challenges remain. Here, the authors introduce Cornetto, a method that improves assembly quality, enables genome sequencing from saliva...
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Jimmy Breen @wessidepraxis.bsky.social · 25/11/2025
Great opportunity! #ABACBS2025
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Monika Mohenska @mmohenska.bsky.social · 25/11/2025
What and incredible speaker! @zaminiqbal.bsky.social I really enjoyed learning all about bacterial plasmids and their evolution. PSA they are also recruiting in Bath UK - go talk to him for the deets #ABACBS2025
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Vijini Mallawaarachchi @vijinim.bsky.social · 24/11/2025
Excited to be at ABACBS 2025. Learning, connecting and growing. 😄🧬💻 #ABACBS2025
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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 21/09/2025
MMseqs2-GPU sets new standards in single query search speed, allows near instant search of big databases, scales to multiple GPUs and is fast beyond VRAM. It enables ColabFold MSA generation in seconds and sub-second Foldseek search against AFDB50. 1/n 📄 www.nature.com/articles/s41... 💿 mmseqs.com
nature.com
GPU-accelerated homology search with MMseqs2 - Nature Methods
Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...
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Rob Edwards @linsalrob.bsky.social · 25/07/2025
🌟 Exciting news! We’re launching three fully-funded postdoc positions for "New Horizons for Synthetic Phages” Join us in tackling antimicrobial resistance with cutting-edge synthetic biology + AI bioinformatics. Based at Flinders Uni in vibrant Adelaide. 👇 Read on for details! #Phage
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Vijini Mallawaarachchi @vijinim.bsky.social · 17/09/2025
Excited to share our latest preprint on agtools, an open-source Python framework for analysing and manipulating assembly graphs. (1/n) www.biorxiv.org/content/10.1... #Bioinformatics #genomics #assembly #assemblygraphs #software
biorxiv.org
agtools: a software framework to manipulate assembly graphs
Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap information, facilitating the assembler to construct longer genomic f...
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George Bouras @gbouras13.bsky.social · 08/08/2025
I also put together an extra ColabFold formatted database of nearly 130M phage proteins that can be used to make better viral protein structure predictions github.com/gbouras13/co...
github.com
GitHub - gbouras13/colabfoldv: Augmented Local MSA Generation for Phage and Viral Proteins using the ColabFold Framework
Augmented Local MSA Generation for Phage and Viral Proteins using the ColabFold Framework - gbouras13/colabfoldv
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George Bouras @gbouras13.bsky.social · 08/08/2025
Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation #phagesky 1/n www.biorxiv.org/content/10.1...
biorxiv.org
Protein Structure Informed Bacteriophage Genome Annotation with Phold
Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents. Here we introduce Phold, an annotation framework utilis...
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 07/08/2025
Protein Structure Informed Bacteriophage Genome Annotation with Phold www.biorxiv.org/content/10.1101/202…
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Vijini Mallawaarachchi @vijinim.bsky.social · 07/08/2025
🚀 I just released agtools – a Python API + CLI for working with assembly graphs! ⚙️ Convert, filter, clean, visualise & more. 📦 Install with pip or conda 📖 Docs & code: github.com/Vini2/agtools ⭐ Feedback, contributions, and stars are welcome! #bioinformatics #python #genomics #opensource
github.com
GitHub - Vini2/agtools: Tools for manipulating assembly graphs
Tools for manipulating assembly graphs. Contribute to Vini2/agtools development by creating an account on GitHub.
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Jim Shaw @jimshaw.bsky.social · 28/05/2025
Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler that I've been working on during my postdoc in the Heng Li lab (@lh3lh3.bsky.social). myloasm-docs.github.io
myloasm-docs.github.io
myloasm - metagenomic assembly with (noisy) long reads
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Susie Grigson @susiegriggo.bsky.social · 30/07/2025
🚨 New preprint 🚨 My phage annotation tool, Phynteny, finally has a preprint and a brand new version powered by a cool AI transformer architecture and protein language models! #phagesky www.biorxiv.org/content/10.1...
biorxiv.org
Synteny-aware functional annotation of bacteriophage genomes with Phynteny
Accurate genome annotation is fundamental to decoding viral diversity and understanding bacteriophage biology; yet, the majority of bacteriophage genes remain functionally uncharacterised. Bacteriopha...
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EMBL-EBI Training @training.ebi.embl.org · 29/05/2025
Earlier this year, with Google DeepMind, we held the AlphaFold Education Summit to increase and strengthen global capacity through train-the-trainer sessions & the co-development of further #AlphaFold training. Now, we can share the free course materials with you: www.ebi.ac.uk/training/mat... 🧪🖥️🧬
 A man smiles at a lectern, talking towards a room. Behind him, a PowerPoint screen is shown with a blue background and the words 'AlphaFold Education Summit. 14 – 16 January 2025. Hinxton, United Kingdom. The EMBL's European Bioinformatics Institute and Google DeepMind logos are also shown on screen.
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Vijini Mallawaarachchi @vijinim.bsky.social · 29/05/2025
Check out our latest publication, GraphBin-Tk, an assembly graph-based metagenomic binning toolkit.
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