iiinova — where your digital self keeps evolving

Reposted by Kevin Forsberg

Vaughn Cooper @vscooper.micropopbio.org · 25/09/2026

FYI to everyone submitting this October NIH cycle You need to re-certify your ScienCV AFTER Sept 26 (tomorrow) for your application or it may not be accepted. Great timing!

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Kevin Forsberg @kvnforsberg.bsky.social · 16/09/2026

Asgards are got dang fascinating. One of the likeliest topics in science to pull my attention away from what I *should* be working on.

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Harmit Singh Malik @harmitmalik.bsky.social · 06/08/2026

Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.

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Jason Nomburg @jnoms.bsky.social · 22/07/2026

Happy to share the first preprint out of the Nomburg lab! Many aspects of cellular immunity are shared across the tree of life. Here, we show that some of these conserved aspects of cellular immunity are mirrored by conserved effectors of immune antagonism. Thread below! 1/15

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Xavier Charpentier @labxc.bsky.social · 07/07/2026

#microsky New preprint from the lab! Widespread immune systems protect bacteria against conjugative plasmids www.biorxiv.org/content/10.6... Kudos to the extremely talented lead author Ludovic Poiré! Key contributions by @francoisrousset.bsky.social and also help from C. Lesterlin/TacC lab. 🧵⬇️

biorxiv.org

Widespread immune systems protect bacteria against conjugative plasmids

Conjugative plasmids are a class of mobile genetic elements capable of efficient transfer between bacterial cells. Although they can introduce beneficial traits such as antibiotic resistance to recipi...

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Kevin Forsberg @kvnforsberg.bsky.social · 02/07/2026

Humans and bacteria share strategies to defend against viruses. We wondered: could they use each other's genes? Yes, both can! Bacteria can use human immune genes to defend against phages AND Human cells can use bacterial genes for viral defense. www.biorxiv.org/content/10.6...

biorxiv.org

Bacterial and human exonucleases mediate interkingdom antiviral immunity

All kingdoms of life have developed strategies to limit viral infection. In humans, interferons induce a suite of antiviral factors that collectively provide immunity. Some human immune genes are homo...

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Kevin Forsberg @kvnforsberg.bsky.social · 26/06/2026

We've pulled up a chair for you and even made you a plate. Join us!

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Kevin Forsberg @kvnforsberg.bsky.social · 13/06/2026

Congratulations @kranzuschlab.bsky.social and @sgfern.bsky.social! A thrilling read borne from a fantastic idea!

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Miguel López Rivera @riveralopz.bsky.social · 29/05/2026

(1/6) Thrilled to share this story! In our preprint from my PhD in the @kranzuschlab.bsky.social, with help from the Hatfull lab and @soreklab.bsky.social, we discover RyDEP, a phage-encoded RyR-domain glycosidase that allows phages to evade Thoeris defense. Highlights below! doi.org/10.64898/202...

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Vivek Mutalik @vivekmutalik.bsky.social · 03/04/2026

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Phage receptor prediction from genome sequencing alone. Bacterial receptor (blue) interacting with phage proteins (purple) is shown here

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Sam Hobbs @hobbslabutah.bsky.social · 22/01/2026

Hello world! I am excited to announce my lab is open at the University of Utah in the Department of Biochemistry. We are looking for scientists at all levels interested in studying host-virus interactions in both bacteria and animals. Come join us in beautiful Utah! (photo is 10 steps from lab)

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Dorentina Humolli @humollidorentina.bsky.social · 20/11/2025

🚀New preprint from our lab! I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡 Continue reading (🧵)

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Alexander Harms @aharms485.bsky.social · 20/11/2025

🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages. Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms. A thread 1/8

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Claus Wilke @clauswilke.com · 07/10/2025

Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon. blog.genesmindsmachines.com/p/we-still-c...

blog.genesmindsmachines.com

We still can’t predict much of anything in biology

Biology is hard. Yes, even for AI.

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Kara McKinley @karalmckinley.bsky.social · 10/10/2025

Lab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!

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Roni Odai @rodai.bsky.social · 02/10/2025

Viral AlphaFold Database (VAD) is live in Science Advances ~27,000 predicted viral protein monomers & homodimers Conserved folds across bacteria, archaea & eukaryotic viruses New toxin–antitoxin system KreTA uncovered Vast “functional darkness” remains uncharted www.science.org/doi/10.1126/...

science.org

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes

VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.

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Reposted by Kevin Forsberg

Mark Mandel @markjmandel.bsky.social · 24/09/2025

Join us on Friday at noon for a great seminar from Tera Levin @teralevin.bsky.social! @uwmadisonmmi.bsky.social

Announcement: Medical Microbiology & Immunology Seminar Series, September 26, 12:00 pm, MSB 1520. "The Evolution of Immunity and Pathogenesis within Environmental Microbial Battlegrounds". Dr. Tera Levin, University of Pittsburgh.

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Kevin Forsberg @kvnforsberg.bsky.social · 17/09/2025

Photosynthetic slugs ??!!??! (also, I love the name 'kleptosome' for an organelle).

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Kevin Forsberg @kvnforsberg.bsky.social · 18/08/2025

Come be my colleague! I've been very happy at UTSW Micro. Why? Its a supportive environment full of excellent people. There's strong ambition, reflexive empathy, and excellent resources.

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Kevin Forsberg @kvnforsberg.bsky.social · 30/07/2025

Our lab’s 1st manuscript was also Elsevier’s first test case for complying with the new NIH Public Access Policy. It was a bit tricky to figure out how to make everybody happy (you could put that on my epitaph...) A🧵 on how I threaded this needle of compliance!

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Aude Bernheim @audeber.bsky.social · 24/07/2025

🦠🧍‍♀️From bacterial to human immunity. We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity. Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social www.science.org/doi/10.1126/...

science.org

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Sternberg Lab @sternberglab.bsky.social · 11/06/2025

1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: www.biorxiv.org/content/10.1...

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Amy Conte @amyconte.bsky.social · 04/06/2025

Excited to share that my work in the @aaronwhiteley.bsky.social lab describing chaperone-mediated phage sensing by a bacterial NLR-related protein is out in @plosbiology.org!

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Kevin Forsberg @kvnforsberg.bsky.social · 03/03/2025

My lab’s first preprint! We used functional metagenomics to identify phage defenses in human and soil microbiomes. We scaled these selections while maintaining accuracy, enabling us to examine 9 habitats for defense elements against 7 phages. www.biorxiv.org/content/10.1... 1/10

Functional Metagenomic Selections for Phage Defense

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Science News @scinews.bsky.social · 24/11/2024

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky 1. The importance of stupidity in scientific research Open Access journals.biologists.com/jcs/article/...

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Aude Bernheim @audeber.bsky.social · 16/12/2024

Out in NAR, AntiDefenseFinder & our "systematic" analysis of inhibitors of antiphage systems wt Bondy-Denomy lab led by @ftesson.bsky.social and E. Huiting. Not so "systematic" as very few known, fun stuff on MGE, antidefense islands and cool phages exaptations! academic.oup.com/nar/advance-...

academic.oup.com

Exploring the diversity of anti-defense systems across prokaryotes, phages and mobile genetic elements

Abstract. The co-evolution of prokaryotes, phages and mobile genetic elements (MGEs) has driven the diversification of defense and anti-defense systems ali

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Reposted by Kevin Forsberg

Scott Saunders @saunderslab.bsky.social · 22/11/2024

Wow - bluesky! 📈 🦠 Please help me amplify a special faculty search. We're looking for someone in "Microbial Systems Biology" to join me and @kreynoldslab.bsky.social at UTSW Sys Bio / Bioinformatics. There is an empty lab space right next to us waiting for you! apply.interfolio.com/154339 1/4

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Kevin Forsberg @kvnforsberg.bsky.social · 15/11/2024

Oh boy! @harmitmalik.bsky.social is on bluesky?!? It's getting real! I can feel the added gravitas.

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Kevin Forsberg @kvnforsberg.bsky.social · 03/09/2024

Come be my colleague! I've been very, very happy at UTSW Micro. Supportive environment. Strong ambition. Strong empathy. Excellent resources. jobs.utsouthwestern.edu/job/20847915...

jobs.utsouthwestern.edu

Job Details

Discover Assistant Professor in Microbial Pathogenesis and other Faculty and Physicians jobs in Dallas, TX and apply online today!

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Vaughn Cooper @vscooper.micropopbio.org · 09/10/2023

🚨My department is HIRING🚨 Microbiology & Molecular Genetics at University of Pittsburgh School of Medicine invites applicants for tenure-track microbiology faculty at the Assistant or Associate Professor level. Our scope is broad, we seek creative colleagues! More info: tinyurl.com/PittMMG-Jobs

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Kevin Forsberg @kvnforsberg.bsky.social · 20/09/2023

Come be my colleague! The Bioinformatics Dept at UT Southwestern has a new TT faculty position open in microbial systems biology, broadly defined: apply.interfolio.com/132461

apply.interfolio.com

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

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Reposted by Kevin Forsberg

Ben Adler @benadler.bsky.social · 19/09/2023

I’m really excited to share our new pre-print “Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi”, with co-first author Muntathar Al-Shimary from the Doudna and the newly-minted Cress labs! www.biorxiv.org/content/10.1...

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