Sign in

Fabian Streit

@fstreit.bsky.social
204 followers 348 following 34 posts

psychologist|@zi_mannheim|psychiatric genetics|stress depression pgc.unc.edu/for-researchers/working-groups/mdd personality disorders zi-mannheim.de/pdgg german national cohort nako.de/en/research/expert-groups/neurological-and-psychiatric-diseases

PostsRepliesMedia
Reposted by Fabian Streit
Michel Nivard @michelnivard.bsky.social · 02/09/2026
🚨& 🧵 Our new Nature paper is out! Across 46 cohorts and up to 1.14M people per Big Five trait, we do GWAS and ask how robust, generalizable and consequential the genetic signals underlying personality really are. www.nature.com/articles/s41...
nature.com
614268
Fabian Streit @fstreit.bsky.social · 03/09/2026
Congrats, happy we could contribute a bit!
240
Reposted by Fabian Streit
Brock Kirwan @brockkirwan.com · 13/08/2026
In honor of International Left-Handers Day, we have an updated preprint on scanning left-handed participants in fMRI studies. Although they're 11% of the population, we routinely screen LH people out of fMRI studies due to concerns about functional lateralization 1/n www.biorxiv.org/content/10.1...
biorxiv.org
Left Out: The Effect of Handedness on fMRI Activation in Memory Paradigms
About 11% of the population is left-handed, a significant minority of the potential participant pool for functional MRI (fMRI) studies. However, convention in fMRI research dictates these potential pa...
47031
Reposted by Fabian Streit
International Society of Psychiatric Genetics @ispg.bsky.social · 11/08/2026
#WCPG26 kicks off seven weeks from today! Are you registered yet? #Glasgow #ISPG #PsychiatricGenetics #WorldCongress
001
Reposted by Fabian Streit
Nature Portfolio @natureportfolio.nature.com · 26/07/2026
Genome-wide association analyses identify risk variants for borderline personality disorder and find genetic correlations with psychiatric disorders, behavioral traits and somatic diseases, according to a paper in Nature Genetics. go.nature.com/3Tlk0Bx 🧬🧪
This is figure 2, which shows the Manhattan plot of the GWAS of BPD.
0134
Fabian Streit @fstreit.bsky.social · 22/07/2026
This has been a long time in the making: Our genome-wide association study (GWAS) of borderline personality disorder (BPD) is now out in Nature Genetics. www.nature.com/articles/s41... 1/7
240
Reposted by Fabian Streit
Science X / Phys.org @sciencex.bsky.social · 20/07/2026
The largest genetic analysis of borderline personality disorder identified 11 independent risk regions and nine candidate genes, using data from about 13,000 affected people and 1.1 million controls. doi.org/hcb6qq
medicalxpress.com
Largest genetic analysis of borderline personality disorder identifies 11 risk regions and nine genes
An international team led by the Central Institute of Mental Health in Mannheim has presented the largest genome-wide association study on borderline personality disorder to date.
001
Reposted by Fabian Streit
Scott McGrath @smcgrath.phd · 20/07/2026
🧪 Data from 12,339 people with borderline personality disorder powered the largest GWAS for the condition so far. They mapped 11 associated genomic locations, explaining about 17% of inherited risk. The strongest genetic correlation they found was with PTSD. 🧬💻
nature.com
Huge study finds first genetic clues for borderline personality disorder
Largest genetic analysis of the condition so far finds 11 linked locations in the human genome.
1103
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 09/06/2026
📢 New publication in @nathumbehav.nature.com from the PGC Anxiety Working Group: the largest GWAS of generalised anxiety symptoms to date, analysing ~700k across 14 cohorts. We found 74 genome-wide significant loci, 39 novel for anxiety.
1155
Fabian Streit @fstreit.bsky.social · 19/05/2026
Great new preprint by the @pgcgenetics.bsky.social Suicide Working Group, investigating shared and distinct genetic contributions to different suicidality phenotypes!!!
010
Reposted by Fabian Streit
Aysu Okbay @aysuo.bsky.social · 25/03/2026
Come work with me and @dr-appie.bsky.social in Amsterdam!
0126
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 12/03/2026
There is high symptom and genetic overlap across psychiatric conditions. @andrewgrotzinger.bsky.social et al. (2025) explored this using our #GWAS data of over 1 mil cases across 14 conditions. They assessed the genetic architecture and the functional roles of genes across these conditions.
141
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 01/03/2026
🧵 New publication from the PGC Anxiety Working Group. Our GWAS meta-analysis of anxiety disorders is now published in @natgenet.nature.com! 🔗: doi.org/10.1038/s415...
12817
Reposted by Fabian Streit
PsyGenOmics @psygenomics.bsky.social · 17/02/2026
New report by the PGC outreach committee: From Genomes to Conversations: Outreach and Engagement in Psychiatric Genetics (2026) An important contribution on why dialogue, and responsible communication must be integral to psychiatric genetics. link.springer.com/article/10.1...
link.springer.com
From Genomes to Conversations: Outreach and Engagement in Psychiatric Genetics - Behavior Genetics
Outreach in psychiatric genetics bridges the gaps across research advancements, clinical practice, and public understanding. Effective communication with a range of audiences faces multiple challenges...
032
Reposted by Fabian Streit
Na Cai @caina89.bsky.social · 16/02/2026
My department @bsse.ethz.ch is inviting applications for a new assistant professor (tenure-track) in computational immunology, interested candidates please see advert and apply! Deadline 15 April 2026 ethz.ch/en/the-eth-z...
ethz.ch
Assistant Professor (Tenure Track) of Computational Immunology
012
Reposted by Fabian Streit
medRxivpreprint @medrxivpreprint.bsky.social · 03/02/2026
Examining the Contribution of Childhood Maltreatment to the Gender Gap in Depression: Insights from the German National Cohort (NAKO) www.medrxiv.org/content/10.64898/20…
011
Fabian Streit @fstreit.bsky.social · 04/02/2026
Happy to share our newest preprint! Depression is more common in females than in males, but it remains insufficiently understood why. Using data from the German National Cohort (NAKO) @nako.de, we investigated whether childhood maltreatment may contribute to this gender gap. doi.org/10.64898/202...
doi.org
Examining the Contribution of Childhood Maltreatment to the Gender Gap in Depression: Insights from the German National Cohort (NAKO)
Background: Childhood maltreatment is a major risk factor for depression and may contribute to sex differences in depression prevalence. We examined sex-specific associations between childhood maltrea...
130
Fabian Streit @fstreit.bsky.social · 04/02/2026
Looking forward to it!
030
Reposted by Fabian Streit
Michael Dufner @michduf.bsky.social · 16/01/2026
New paper out: Some people are systematically better at judging others’ intelligence. Who are the best judges? People WHO are intelligent themselves, have good emotion-perception ability, and who are high in well-being. www.sciencedirect.com/science/arti...
sciencedirect.com
The good judge of intelligence
Accurately judging others' intelligence is important, yet little is known about individual differences in this ability. In this study we investigated …
2247
Fabian Streit @fstreit.bsky.social · 27/01/2026
Happy to share this: we confirmed a significant link between smoking and depression using data from the @nako.de. Our analysis of over 170,000 participants shows that both current and former smokers face a higher lifetime risk of depression. #MentalHealth #ResearchNews #PublicHealth
182
Reposted by Fabian Streit
Science X / Phys.org @sciencex.bsky.social · 22/01/2026
Analysis of over 170,000 adults indicates that current and former smokers experience depression more frequently than never-smokers, with risk decreasing the longer a person has quit smoking. doi.org/hbk2gw
medicalxpress.com
Link between smoking and depression confirmed in study
A research group led by the Central Institute of Mental Health (CIMH) in Mannheim has confirmed for the first time within the German National Cohort (NAKO) an association between cigarette consumption and depression.
032
Reposted by Fabian Streit
Michel Nivard @michelnivard.bsky.social · 22/01/2026
A very comprehensive review of the genetics of personlity led by @tedmond.bsky.social This is a great onramp for those who haven't checked into psychiatric genetics or bahviour genetics in a while. www.annualreviews.org/content/jour...
annualreviews.org
Personality Genomics
Recent research advances have precipitated the era of personality genomics: the study of how variation in human DNA sequence predicts individual differences in characteristic patterns of thinking, fee...
33112
Reposted by Fabian Streit
Michel Nivard @michelnivard.bsky.social · 07/01/2026
This is an interesting challenge, Its A LOT of data for psychology, but not for ML perse. I wonder whether there is juice to be squeezed out of other EMA data, which would only have partial feature overlap, loads of other EMA data lives here: openesmdata.org.
openesmdata.org
OpenESM: Open Experience Sampling Method Database
<!DOCTYPE html> OpenESM: Open Experience Sampling Method Database A database of open experience sampling datasets openESM is a database of harmonized openly available experience sampling datasets. The...
141
Reposted by Fabian Streit
Ruben C. Arslan @ruben.the100.ci · 03/12/2025
Want to make nice graphs with me, starting next year? I'm hiring for a position at the University of Witten/Herdecke. uni-wh.softgarden.io/job/61280592...
 ‘A fragmented field: Construct and measure proliferation in psychology.’ (2025)From ‘Language models accurately infer correlations between psychological items and scales from text alone.’ (2025)From ‘Not within spitting distance: salivary immunoassays of estradiol have subpar validity for predicting cycle phase.’ (2023)Work in progress with cycle tracking data from the app Clue
26051
Reposted by Fabian Streit
Sarah Colbert @sarahcolbert.bsky.social · 27/10/2025
🚨New preprint from PGC SUI!! @pgcgenetics.bsky.social GWAS meta-analyses of suicidal ideation, attempt, death, and behavior across >50 cohorts identify 77 loci (59 novel), implicate subcortical brain regions, and show suicidality phenotypes are genetically distinct. www.medrxiv.org/content/10.1...
medrxiv.org
Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights
Suicidality is heritable and a leading cause of global morbidity and mortality, yet its biological etiology remains largely elusive. We conducted multi-ancestry genome-wide association study meta-anal...
095
Reposted by Fabian Streit
Philippe Jawinski @pjawinski.bsky.social · 07/10/2025
🧠 Why do some brains age faster than others? 🧬 Our new Nature Aging study of over 56,000 participants explores the genetics of the “brain age gap” — the difference between your brain’s biological and chronological age. nature.com/articles/s43587-025-00962-7 Thread below 👇
nature.com
Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health - Nature Aging
This genomic study of magnetic resonance imaging-based brain age in 56,348 people identifies 59 genetic loci, links brain aging to mental and physical health, and suggests high blood pressure and type 2 diabetes as causal factors of brain aging.
12616
Reposted by Fabian Streit
medRxivpreprint @medrxivpreprint.bsky.social · 28/09/2025
Breaking the Norm: Population-Scale Normative Modeling of Brain Structure in Depression and Anxiety www.medrxiv.org/content/10.1101/202…
011
Reposted by Fabian Streit
Marc L Seal @parkvillegeek.bsky.social · 29/09/2025
Breaking the Norm: Population-Scale Normative Modeling of Brain Structure in Depression and Anxiety | medRxiv www.medrxiv.org/content/10.1...
041
Reposted by Fabian Streit
Jonathan Sebat @sebatlab.bsky.social · 16/07/2025
The field of neuroscience views the goal of human genetics as "finding genes". This is an outdated view. In whole genome studies of rare variants, finding genes is the easy part. The more interesting and important goal is to map out the causal pathway from genes to brain function to cognitive traits
29530
Reposted by Fabian Streit
DurstewitzLab @durstewitzlab.bsky.social · 13/07/2025
Got prov. approval for 2 major grants in Neuro-AI & Dynamical Systems Reconstruction, on learning & inference in non-stationary environments, out-of-domain generalization, and DS foundation models. To all AI/math/DS enthusiasts: Expect job announcements (PhD/PostDoc) soon! Feel free to get in touch.
0348
Reposted by Fabian Streit
Iiris Hovatta @iirishovatta.bsky.social · 10/07/2025
I’m excited to share our genetic study on panic disorder in the FinnGen sample. We found a genomewide significant hit within the SORCS3 gene and showed that SORCS3 serum protein levels were 40% higher in panic disorder patients compared to controls medrxiv.org/cgi/content/...
medrxiv.org
Genome-wide Association Study Identifies SORCS3 as a Novel Susceptibility Locus for Panic Disorder in the FinnGen Study
Panic disorder is an anxiety disorder with poorly understood etiology. Although twin studies suggest modest heritability (∼40%), few genetic variants have been associated with it. We carried out a gen...
001
Reposted by Fabian Streit
Danielle @daniposthu.bsky.social · 24/05/2025
#ctglab is hiring! We have #vacancies! 2 PhD & 2 postdoc positions, in #statistical #genetics and/or #bioinformatics - if you like GWAS, method development and linking with biology - check these out 👇 werkenbij.vu.nl/vacatures/tw... werkenbij.vu.nl/vacatures/po... werkenbij.vu.nl/vacatures/po...
046
Fabian Streit @fstreit.bsky.social · 20/05/2025
Great to see this paper finally online, and happy we could contribute (a bit) to it! It's a big progress in regard to variant discovery (especially for the other 4 Big 5) but Ted and team also ran a wide range of super interesting follow-up analyses, that showcase the potential of the results. 🥳🧬
081
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 14/05/2025
We are currently looking for new collaborators with genotyping and autism data in order to increase our sample size for our next large-scale genome-wide meta-analyses of autism. Want to contribute? Contact us! 📩 pgc.unc.edu/for-research...
pgc.unc.edu
Autism Working Group – PGC
022
Reposted by Fabian Streit
Michel Nivard @michelnivard.bsky.social · 12/05/2025
🚨 I just released the alpha-version of my AI in Genomics textbook! It covers (so far!) sequence language models & deep learning for DNA/RNA/proteins. Check it out: biobook.michel.science
biobook.michel.science
Sequence Language Models & Deep Learning in Genomics
17213
Reposted by Fabian Streit
Miguel Branco @brancolab.bsky.social · 23/04/2025
So depressing...
046
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 15/04/2025
🎉Hello and welcome to the PGC Africa Working Group takeover 🎉 For the next 2 weeks, we will share with you exciting updates from @pgc-africa.bsky.social brought to you by @jaredgm.bsky.social and Ofure Ubah 1/4
164
Reposted by Fabian Streit
Cathryn Lewis @cathrynlewis.bsky.social · 08/04/2025
Postdoc closing soon - two more days to apply for our statistical genetics role in antidepressant response at @kingsioppn.bsky.social
032
Reposted by Fabian Streit
Fiona Hagenbeek @fionahagenbeek.bsky.social · 06/04/2025
Our new study in Molecular Psychiatry, in 1528 children and their parents (@ntrbiopsy.bsky.social) shows that indirect genetic effects—where parental genetics shape offspring traits via environmental influences (genetic nurture)—impact DNA methylation of children. doi.org/10.1038/s413... (1/5)
doi.org
Intergenerational transmission of complex traits and the offspring methylome - Molecular Psychiatry
Molecular Psychiatry - Intergenerational transmission of complex traits and the offspring methylome
12612
Reposted by Fabian Streit
ALBA Network @network-alba.bsky.social · 02/04/2025
🎉 Great news from @ebbsociety.bsky.social 👏 Congrats to our Chair, @francescacirulli.bsky.social, for receiving the Diversity Award in recognition of her dedication to fostering diversity and inclusion in research! 📅Join us in celebrating this achievement at the ALBA session at #EBBS2025
2246
Reposted by Fabian Streit
MES Forschungssysteme @mes4schung.bsky.social · 20/03/2025
🚨Attention research friends in Heidelberg/Mannheim, we have exiting news. You are warmly invited to join us for a day of networking and sharing science, the keynote will be given by @gordonfeld.bsky.social ⭐! Come and get your ticket at: www.eventbrite.com/e/brain-days...
eventbrite.com
Brain Days Heidelberg
Get ready to expand your research network at Brain Days Heidelberg -Keynote Talk- Hands-on-workshop and more...
022
Reposted by Fabian Streit
Alice Braun @alicebraun.bsky.social · 12/03/2025
The Ripke lab has worked on a new stable release of RICOPILI! Updates include compatibility with GRCh38 and imputation using Minimac4. A software tarball and YAML file are provided to help resolve dependency issues: github.com/Ripkelab/ric... Any feedback is highly welcome! @pgcgenetics.bsky.social
github.com
GitHub - Ripkelab/ricopili: Main ricopili repo for public releases
Main ricopili repo for public releases. Contribute to Ripkelab/ricopili development by creating an account on GitHub.
0167
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 06/03/2025
We asked three chairs of PGC Working Groups: what is the goal for their research this year? @niamhmullins.bsky.social, Barbara Franke and @egatkinson.bsky.social #womeninSTEM #InternationalWomensDay2025
0144
Reposted by Fabian Streit
Penelope Lind @penelopelind.bsky.social · 15/01/2025
It is wonderful to be able to share the latest PGC major depression GWAS that included results from our Australian Genetics of Depression Study. Large scale GWAS meta-analyses aren't possible without collaboration between hundreds of researchers and hundreds of thousands of study participants.
011
Reposted by Fabian Streit
Eivind Ystrom @eivindy.bsky.social · 14/01/2025
Want to get out of Dodge? Do a postdoc @uio.no! You will be using the MoBa study and registers to study intergenerational transmission and GxE for #MentalHealth and #education using @behaviorgenetic.bsky.social and @pgcgenetics.bsky.social approaches. Please share! www.jobbnorge.no/en/available...
jobbnorge.no
Postdoctoral Fellowship in Mental Health Research (272560) | University of Oslo
Job title: Postdoctoral Fellowship in Mental Health Research (272560), Employer: University of Oslo, Deadline: Monday, February 24, 2025
12727
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 14/01/2025
1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social. www.cell.com/cell/fulltex... A thread 🧵:
Article screenshot of a genome-wide association study of major depression published in the journal Cell
47425
Reposted by Fabian Streit
Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · 14/01/2025
🙏 Our collaborators (1/2) @evacschulte.bsky.social @psygenomics.bsky.social @annadocherty.bsky.social@klehto.bsky.social @ymilaneschi.bsky.social @jonicoleman.bsky.social @markjamesadams.bsky.social @cathrynlewis.bsky.social @docknowles.bsky.social @mcintosh2001.bsky.social @fstreit.bsky.social
182
Reposted by Fabian Streit
Mark James Adams @markjamesadams.bsky.social · 14/01/2025
New study from the @pgcgenetics.bsky.social: Multi-ancestry GWAS of MDD in over half a million cases and 4 million controls. www.cell.com/cell/fulltex...
cell.com
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
Trans-ancestry GWAS of major depression identifies 697 genetic variants and 308 genes, implicating neural and molecular mechanisms and drug repurposing opportunities.
22318
Reposted by Fabian Streit
Gerome Breen @psychgenomics.bsky.social · 02/12/2024
Please apply for this postdoc analyst position in the UK's Eating Disorders Clinical Research Network. #eatingdisorders #treatment #epidemiology #genetics - DM if any questions www.jobs.ac.uk/job/DKR331/r...
jobs.ac.uk
Research Fellow (Statistician) – Eating Disorders Clinical Research Network at King's College London
Recruiting now: Research Fellow (Statistician) – Eating Disorders Clinical Research Network on jobs.ac.uk. Click for details and explore more academic job opportunities on the top job board
11419
Reposted by Fabian Streit
Micah G. Allen @micahgallen.com · 02/12/2024
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
A screenshot of a paper on bioarxiv illustrating the lack of blue sky share button!
9385196