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Eszter Lakatos

@eszterlakatos.bsky.social
710 followers 102 following 13 posts

Computational biologist fascinated by (cancer) genomes. Cyclist, climber and amateur singer on the side. Assistant Prof at Chalmers.

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Reposted by Eszter Lakatos
David Basanta @cancerevo.org · 14/01/2026
Sunny Crete for a great meeting about #cancer #ecology and #evolution
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Eszter Lakatos @eszterlakatos.bsky.social · 25/11/2025
Still a few days to apply for a PhD studentship in my lab as part of the MSCA doctoral training network EVOMG! Come help us develop informative models of blood-based biopsies in cancer, and learn about the various evolutionary aspects that can aid medicine. More info and application: www.evomg-dn.eu
evomg-dn.eu
EVOMG-DN
EvoMG-DN is a European Doctoral Network funded by the Horizon Europe Marie Skłodowska-Curie Actions (MSCA), composed of 14 beneficiaries and associated partners from both academic and non-academic sectors.
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Eszter Lakatos @eszterlakatos.bsky.social · 14/11/2025
Check out our article on the evolution of immune evasion in colorectal cancer. ⬇️ For a summary, see our Research Briefing now available online: rdcu.be/ePWC4
rdcu.be
Timing and mechanisms of immune evasion in colorectal cancers
Nature Genetics - Evading elimination by the immune system is a hallmark of cancer, but the exact timing and pathways of immune evasion are still to be explored. Colorectal cancers were found to...
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Vinaya Gunasri @vinaya-gunasri.bsky.social · 07/11/2025
Now that our Nature Genetics paper is out, here’s a “Behind the Paper” post on how colorectal cancers outsmart the immune system from the beginning. 👉 communities.springernature.com/posts/when-c... @eszterlakatos.bsky.social @trevorgraham.bsky.social #CancerResearch #Immunology #TME #Epigenetics
communities.springernature.com
When Cancers Outsmart the Immune System from the Very Beginning
Cancer research is often seen as an arms race between the immune system and cancer cells, unfolding gradually as tumors grow. But our new study on colorectal cancer suggests otherwise: the battle may ...
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Trevor Graham @trevorgraham.bsky.social · 05/11/2025
New @natgenet.nature.com paper from the brilliant @eszterlakatos.bsky.social presents evidence that chromatin alterations disrupt antigen presentation & neoantigens in colorectal cancer. Also that immune escape is part of the "Big Bang", at the outset of CRC growth. www.nature.com/articles/s41...
nature.com
Epigenetically driven and early immune evasion in colorectal cancer evolution - Nature Genetics
This study nominates immune escape as an early event in colorectal cancer and shows how this can be driven through both genetic and epigenetic changes.
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 07/10/2025
📢 EvoMG-DN PhD applications are now open! Join our EU-funded MSCA network and explore evolution, ageing, and disease. 👉 www.evomg-dn.eu 📅 Apply by 30 November 2025 #PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers
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Hannah Meyer @hannahvmeyer.bsky.social · 25/07/2025
Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!
cell.com
T cell receptor cross-reactivity prediction improved by a comprehensive mutational scan database
Banerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem...
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MwahahahahahadScientist @mads100tist.bsky.social · 02/10/2024
Sleep when the baby sleeps, eat when the baby eats, edit your manuscript when the baby edits their manuscript
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Vinaya Gunasri @vinaya-gunasri.bsky.social · 04/07/2025
🏆 Honoured to receive the 2025 Inaugural BACR Early Career Award! Grateful to @thebacr.bsky.social and all who’ve supported me — esp. @trevorgraham.bsky.social, @eszterlakatos.bsky.social & @cancerresearchuk.org 💙 Reflections→ www.bacr.org.uk/news/2025-in... #CancerResearch #EarlyCareer #ScienceWins
bacr.org.uk
2025 Inaugural BACR Early Career Award | BACR - The British Association for Cancer Research
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Alejo Rodriguez-Fraticelli @alejofraticelli.bsky.social · 20/06/2025
Very cool story and especially useful mathematical models for everyone to use! Check it out!!!
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Eszter Lakatos @eszterlakatos.bsky.social · 11/06/2025
As much as it's a meaningless milestone, the mathematician in me is happy to see exactly 2^10 citations on the one random day I decide to finally visit my own Google Scholar :)
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EvoMG Program @evomg-bcn.bsky.social · 23/05/2025
🚨With some delay, we're excited to announce that our proposal for a MSCA Doctoral Network on Evolutionary Medical Genomics (EvoMG-DN) got funded! 🎉 🧬 14 labs and 2 companies across 7 European countries will be coordinated by the EvoMG Joint Program at @crg.eu & @upf.edu. europa.eu/!NNq63m
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eriksahailab.bsky.social @eriksahailab.bsky.social · 14/05/2025
Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th...
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Trevor Graham @trevorgraham.bsky.social · 15/05/2025
Tour de force from @melissabarroux.bsky.social on evolutionary and microenvironmental dynamics of oesophageal adenocarcinoma through neoadjuvant therapy Published @natcancer.nature.com Melissa is an outstanding new clinician scientist.. one to watch. www.nature.com/articles/s43... @icr.ac.uk
nature.com
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma - Nature Cancer
Graham and colleagues analyzed locally advanced esophageal adenocarcinoma clinical trial patient samples and identified major changes in gene expression profiles and immune microenvironment compositio...
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hamiscalculated.bsky.social @hamiscalculated.bsky.social · 06/05/2025
📣Open PhD position in Machine Learning at Uppsala University. Focus: Bayesian mathematical models and methods for biomedicine.
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Michelle Lockley @mlockley.bsky.social · 30/04/2025
Can we use the power of evolution to improve ovarian cancer treatment? Our latest paper says yes! Online now at Cancer Research. Thanks to @trevorgraham.bsky.social coauthors and @cancerresearchuk.org for funding.
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Barts Cancer Institute (Queen Mary University of London) @qmbci.bsky.social · 30/04/2025
📰 Can we use the power of evolution to improve ovarian cancer survival? A surprising approach called adaptive therapy holds promise, according to findings by @mlockley.bsky.social & team at @qmul.ac.uk & @icr.ac.uk. Read more ➡️ www.bci.qmul.ac.uk/general-news... #AACR25 #medsky #oncosky🧪
bci.qmul.ac.uk
Smarter chemotherapy approach could delay drug resistance in ovarian cancer - Barts Cancer Institute - Queen Mary University of London
Adaptive chemotherapy can prolong survival in lab models of ovarian cancer, according to new results. The findings could pave the way for a more effective and gentler approach to treating ovarian canc...
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Calum Gabbutt @calumgabbutt.bsky.social · 24/03/2025
If you're a PhD student interested in using maths to understand cancer, this HCEMM summer school in Szeged, Hungary, is an excellent opportunity. Registration is free and local costs are covered, so apply before 15th April.
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Trevor Graham @trevorgraham.bsky.social · 07/03/2025
Our #Cancer #Evolution summer school runs again 30 June-3 July at the beautiful Genome Campus in Hinxton, UK sponsored by @wellcometrust.bsky.social Ideal for starters in the field; this year's focus is on using genomic data for cancer evo research. Brilliant & inspiring faculty! bit.ly/40nLdDD
bit.ly
Evolutionary Biology and Ecology of Cancer — 20250630
Evolutionary Biology and Ecology of Cancer
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Trevor Graham @trevorgraham.bsky.social · 10/03/2025
We have an opening in our #DataScience core @icr.ac.uk. The post will work on a breadth of topics across #cancer biology, but expertise in spatial data, single cell and data integration are priorities. Details here: jobs.icr.ac.uk/vacancies/11... @jobrxiv.bsky.social
jobs.icr.ac.uk
Data Scientist in Sutton | The Institute of Cancer Research
View details and apply for this Data Scientist vacancy in Sutton. Salary Range: Commencement on the salary range is subject to comparable skills and experience. Future progression is based ...
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Wolfgang Huber @wkhuber.bsky.social · 31/01/2025
Come work at the European Molecular Biology Laboratory in the beautiful science & university city Heidelberg as a Research Software Engineer on R/Bioconductor tools for biological data science and AI ! embl.wd103.myworkdayjobs.com/EMBL/job/Hei...
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Trevor Graham @trevorgraham.bsky.social · 30/01/2025
Delighted our work using aneuploidy as a biomarker of colorectal cancer risk in inflammatory bowel disease is out: gut.bmj.com/content/earl... The initial reaction from patients&families has been overwhelming Led by Ibrahim AlBakir @yosoykit.bsky.social @cancerresearchuk.org @icrlondon.bsky.social
gut.bmj.com
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and dif...
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Trevor Graham @trevorgraham.bsky.social · 21/01/2025
Applications for this "Black Leaders in Cancer" #PhD studentship with our lab @icrlondon.bsky.social close on Thursday... if you know of someone who might be interested please do pass the link on.
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Fran Martínez-Jiménez @franmj88.bsky.social · 04/12/2024
Excited to share our perspective on genetic immune escape alterations and their impact on tumor evolution, metastasis, immunotherapy, and interactions with tumor-extrinsic factors. It was a pleasure collaborating with Diego on this -hope you enjoy the read!☺️ www.sciencedirect.com/science/arti...
sciencedirect.com
Genetic immune escape in cancer: timing and implications for treatment
Genetic immune escape (GIE) alterations pose a significant challenge in cancer by enabling tumors to evade immune detection. These alterations, which …
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Marc Williams @marcjwilliams.bsky.social · 03/12/2024
Our paper on chromosomal abnormalities in normal breast tissue from BRCA carriers came out last week. www.nature.com/articles/s41...
nature.com
Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations - Nature Genetics
Single-cell DNA sequencing identifies recurrent copy number changes in healthy breast tissue from women with wild-type or germline BRCA1 or BRCA2 mutations.
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Fritz Roth @fritzroth.bsky.social · 20/11/2024
Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!
cfopitt.taleo.net
Faculty.Professor.Assistant - Full-Time
Click the link provided to see the complete job description.
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Richard Sever @richardsever.bsky.social · 10/11/2024
Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...
connect.biorxiv.org
bioRxiv expands on Mastodon and Bluesky
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Trevor Graham @trevorgraham.bsky.social · 28/11/2024
We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded
findaphd.com
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Parmvir K Bahia @parmvir.com · 26/11/2024
I suppose now is a good time to introduce #BiologyInNumbers, a #SciComm podcast I have the pleasure of directing, producing & hosting. Thought up by then-President Heiko Enderling, it's a means to learn about @smbmathbiology.bsky.social and research from its members and the wider #mathBio community.
The podcast logo consists of a square where the left half is blue and the right half white. There is a wave form across the top. The text reads Biology in Numbers podcast, and the Society for mathematical biology logo is in the bottom right.
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Lena Boehme @lenamboehme.bsky.social · 21/11/2024
Couldn't wish for a better BlueSky debut post: Our spatial atlas of the developing thymus is now published in Nature! 🥳 www.nature.com/articles/s41... Also check out the other papers in the new Human Cell Atlas collection: www.nature.com/collections/... #singlecell #spatial #multiomics
nature.com
A spatial human thymus cell atlas mapped to a continuous tissue axis - Nature
A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in...
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Andrew Krause @blindmath.bsky.social · 17/11/2024
Join us in Durham for a fully-funded multidisciplinary PhD studying Metals, Microbes, Maths, and Metabolism! Please pass this along to interested candidates who are welcome to contact us directly. Both theoretical and/or experimental backgrounds welcome! iapetus2.ac.uk/studentships...
An aerial photo of the centre of Durham city on a snowy winter day. A river encircles the centre containing Durham's Castle and Cathedral.

Photo courtesy of RJX Media.
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Carlo Maley @cmaley.bsky.social · 15/11/2024
We just published a review of lessons farmers have learned for how to control pesticide resistance from evolving, and how to apply those to oncology to prevent cancers from evolving therapeutic resistance: bit.ly/48OfFdX
bit.ly
Resistance Management for Cancer: Lessons from Farmers
Abstract. One of the main reasons we have not been able to cure cancers is that treatments select for drug-resistant cells. Pest managers face similar challenges with pesticides selecting for pesticid...
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Daniela Barillà @danielabarilla.bsky.social · 10/11/2024
Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬
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Eszter Lakatos @eszterlakatos.bsky.social · 29/01/2024
Still 3 more weeks to apply for a PhD in computational biology/ cancer evolution! If you want to find out more about the many exciting positions in our department, we're doing a hybrid informal intro tomorrow: www.chalmers.se/en/current/c... (Non-Göteborg people can join on Zoom!)
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Benjamin Werner @benjaminwerner.bsky.social · 23/01/2024
We are looking for two enthusisastic scientists to join our work on the evolution of ecDNAs in human cancers. Become part of the great @CancerGrand and join our team eDyNAmiC family. Happy to chat any time. Please contact me and ask for details! www.qmul.ac.uk/jobs/vacanci...
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Eszter Lakatos @eszterlakatos.bsky.social · 08/01/2024
Happy 2024 everyone! If your new year's resolution is to find a PhD (or help someone find a PhD) in computational biology, I've got just the thing 😉:
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Eszter Lakatos @eszterlakatos.bsky.social · 21/12/2023
❣️I am looking for a motivated PhD candidate to join me in creating new methods for unraveling cancer evolution @chalmersuniv❣️ Exciting research (if I may say so), great work atmosphere and superb employment benefits❗️ Find out more and spread the word: www.chalmers.se/en/about-cha...
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