Reposted by Eszter LakatosDavid Basanta @cancerevo.org · 14/01/2026Sunny Crete for a great meeting about #cancer #ecology and #evolution 043
Eszter Lakatos @eszterlakatos.bsky.social · 25/11/2025Still a few days to apply for a PhD studentship in my lab as part of the MSCA doctoral training network EVOMG! Come help us develop informative models of blood-based biopsies in cancer, and learn about the various evolutionary aspects that can aid medicine. More info and application: www.evomg-dn.euevomg-dn.euEVOMG-DNEvoMG-DN is a European Doctoral Network funded by the Horizon Europe Marie Skłodowska-Curie Actions (MSCA), composed of 14 beneficiaries and associated partners from both academic and non-academic sectors. 010
Eszter Lakatos @eszterlakatos.bsky.social · 14/11/2025Check out our article on the evolution of immune evasion in colorectal cancer. ⬇️ For a summary, see our Research Briefing now available online: rdcu.be/ePWC4rdcu.beTiming and mechanisms of immune evasion in colorectal cancersNature Genetics - Evading elimination by the immune system is a hallmark of cancer, but the exact timing and pathways of immune evasion are still to be explored. Colorectal cancers were found to... 031
Reposted by Eszter LakatosVinaya Gunasri @vinaya-gunasri.bsky.social · 07/11/2025Now that our Nature Genetics paper is out, here’s a “Behind the Paper” post on how colorectal cancers outsmart the immune system from the beginning. 👉 communities.springernature.com/posts/when-c... @eszterlakatos.bsky.social @trevorgraham.bsky.social #CancerResearch #Immunology #TME #Epigeneticscommunities.springernature.comWhen Cancers Outsmart the Immune System from the Very BeginningCancer research is often seen as an arms race between the immune system and cancer cells, unfolding gradually as tumors grow. But our new study on colorectal cancer suggests otherwise: the battle may ... 041
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 05/11/2025New @natgenet.nature.com paper from the brilliant @eszterlakatos.bsky.social presents evidence that chromatin alterations disrupt antigen presentation & neoantigens in colorectal cancer. Also that immune escape is part of the "Big Bang", at the outset of CRC growth. www.nature.com/articles/s41...nature.comEpigenetically driven and early immune evasion in colorectal cancer evolution - Nature GeneticsThis study nominates immune escape as an early event in colorectal cancer and shows how this can be driven through both genetic and epigenetic changes. 23011
Reposted by Eszter LakatosEVOMG-Doctoral Network @evomg-dn.bsky.social · 07/10/2025📢 EvoMG-DN PhD applications are now open! Join our EU-funded MSCA network and explore evolution, ageing, and disease. 👉 www.evomg-dn.eu 📅 Apply by 30 November 2025 #PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers 0813
Reposted by Eszter LakatosHannah Meyer @hannahvmeyer.bsky.social · 25/07/2025Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!cell.comT cell receptor cross-reactivity prediction improved by a comprehensive mutational scan databaseBanerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem... 32011
Reposted by Eszter LakatosMwahahahahahadScientist @mads100tist.bsky.social · 02/10/2024Sleep when the baby sleeps, eat when the baby eats, edit your manuscript when the baby edits their manuscript 719424
Reposted by Eszter LakatosVinaya Gunasri @vinaya-gunasri.bsky.social · 04/07/2025🏆 Honoured to receive the 2025 Inaugural BACR Early Career Award! Grateful to @thebacr.bsky.social and all who’ve supported me — esp. @trevorgraham.bsky.social, @eszterlakatos.bsky.social & @cancerresearchuk.org 💙 Reflections→ www.bacr.org.uk/news/2025-in... #CancerResearch #EarlyCareer #ScienceWinsbacr.org.uk2025 Inaugural BACR Early Career Award | BACR - The British Association for Cancer Research 362
Reposted by Eszter LakatosAlejo Rodriguez-Fraticelli @alejofraticelli.bsky.social · 20/06/2025Very cool story and especially useful mathematical models for everyone to use! Check it out!!! 183
Eszter Lakatos @eszterlakatos.bsky.social · 11/06/2025As much as it's a meaningless milestone, the mathematician in me is happy to see exactly 2^10 citations on the one random day I decide to finally visit my own Google Scholar :) 040
Reposted by Eszter LakatosEvoMG Program @evomg-bcn.bsky.social · 23/05/2025🚨With some delay, we're excited to announce that our proposal for a MSCA Doctoral Network on Evolutionary Medical Genomics (EvoMG-DN) got funded! 🎉 🧬 14 labs and 2 companies across 7 European countries will be coordinated by the EvoMG Joint Program at @crg.eu & @upf.edu. europa.eu/!NNq63m 11811
Reposted by Eszter Lakatoseriksahailab.bsky.social @eriksahailab.bsky.social · 14/05/2025Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th... 02017
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 15/05/2025Tour de force from @melissabarroux.bsky.social on evolutionary and microenvironmental dynamics of oesophageal adenocarcinoma through neoadjuvant therapy Published @natcancer.nature.com Melissa is an outstanding new clinician scientist.. one to watch. www.nature.com/articles/s43... @icr.ac.uknature.comEvolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma - Nature CancerGraham and colleagues analyzed locally advanced esophageal adenocarcinoma clinical trial patient samples and identified major changes in gene expression profiles and immune microenvironment compositio... 11810
Reposted by Eszter Lakatoshamiscalculated.bsky.social @hamiscalculated.bsky.social · 06/05/2025📣Open PhD position in Machine Learning at Uppsala University. Focus: Bayesian mathematical models and methods for biomedicine. 121
Reposted by Eszter LakatosMichelle Lockley @mlockley.bsky.social · 30/04/2025Can we use the power of evolution to improve ovarian cancer treatment? Our latest paper says yes! Online now at Cancer Research. Thanks to @trevorgraham.bsky.social coauthors and @cancerresearchuk.org for funding. 193
Reposted by Eszter LakatosBarts Cancer Institute (Queen Mary University of London) @qmbci.bsky.social · 30/04/2025📰 Can we use the power of evolution to improve ovarian cancer survival? A surprising approach called adaptive therapy holds promise, according to findings by @mlockley.bsky.social & team at @qmul.ac.uk & @icr.ac.uk. Read more ➡️ www.bci.qmul.ac.uk/general-news... #AACR25 #medsky #oncosky🧪bci.qmul.ac.ukSmarter chemotherapy approach could delay drug resistance in ovarian cancer - Barts Cancer Institute - Queen Mary University of LondonAdaptive chemotherapy can prolong survival in lab models of ovarian cancer, according to new results. The findings could pave the way for a more effective and gentler approach to treating ovarian canc... 3197
Reposted by Eszter LakatosCalum Gabbutt @calumgabbutt.bsky.social · 24/03/2025If you're a PhD student interested in using maths to understand cancer, this HCEMM summer school in Szeged, Hungary, is an excellent opportunity. Registration is free and local costs are covered, so apply before 15th April. 0105
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 07/03/2025Our #Cancer #Evolution summer school runs again 30 June-3 July at the beautiful Genome Campus in Hinxton, UK sponsored by @wellcometrust.bsky.social Ideal for starters in the field; this year's focus is on using genomic data for cancer evo research. Brilliant & inspiring faculty! bit.ly/40nLdDDbit.lyEvolutionary Biology and Ecology of Cancer — 20250630Evolutionary Biology and Ecology of Cancer 02616
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 10/03/2025We have an opening in our #DataScience core @icr.ac.uk. The post will work on a breadth of topics across #cancer biology, but expertise in spatial data, single cell and data integration are priorities. Details here: jobs.icr.ac.uk/vacancies/11... @jobrxiv.bsky.socialjobs.icr.ac.ukData Scientist in Sutton | The Institute of Cancer ResearchView details and apply for this Data Scientist vacancy in Sutton. Salary Range: Commencement on the salary range is subject to comparable skills and experience. Future progression is based ... 01912
Reposted by Eszter LakatosWolfgang Huber @wkhuber.bsky.social · 31/01/2025Come work at the European Molecular Biology Laboratory in the beautiful science & university city Heidelberg as a Research Software Engineer on R/Bioconductor tools for biological data science and AI ! embl.wd103.myworkdayjobs.com/EMBL/job/Hei... 23316
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 30/01/2025Delighted our work using aneuploidy as a biomarker of colorectal cancer risk in inflammatory bowel disease is out: gut.bmj.com/content/earl... The initial reaction from patients&families has been overwhelming Led by Ibrahim AlBakir @yosoykit.bsky.social @cancerresearchuk.org @icrlondon.bsky.socialgut.bmj.comLow-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitisBackground The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and dif... 35613
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 21/01/2025Applications for this "Black Leaders in Cancer" #PhD studentship with our lab @icrlondon.bsky.social close on Thursday... if you know of someone who might be interested please do pass the link on. 099
Reposted by Eszter LakatosFran Martínez-Jiménez @franmj88.bsky.social · 04/12/2024Excited to share our perspective on genetic immune escape alterations and their impact on tumor evolution, metastasis, immunotherapy, and interactions with tumor-extrinsic factors. It was a pleasure collaborating with Diego on this -hope you enjoy the read!☺️ www.sciencedirect.com/science/arti...sciencedirect.comGenetic immune escape in cancer: timing and implications for treatmentGenetic immune escape (GIE) alterations pose a significant challenge in cancer by enabling tumors to evade immune detection. These alterations, which … 1267
Reposted by Eszter LakatosMarc Williams @marcjwilliams.bsky.social · 03/12/2024Our paper on chromosomal abnormalities in normal breast tissue from BRCA carriers came out last week. www.nature.com/articles/s41...nature.comLuminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations - Nature GeneticsSingle-cell DNA sequencing identifies recurrent copy number changes in healthy breast tissue from women with wild-type or germline BRCA1 or BRCA2 mutations. 1168
Reposted by Eszter LakatosFritz Roth @fritzroth.bsky.social · 20/11/2024Calling all systems and computational biologists in search of a faculty position: We have Assistant and Associate Professor positions! 🚀 Pittsburgh is beautiful, and we are doing amazing science here. cfopitt.taleo.net/careersectio... cfopitt.taleo.net/careersectio... Please apply by Dec 2!cfopitt.taleo.netFaculty.Professor.Assistant - Full-TimeClick the link provided to see the complete job description. 06174
Reposted by Eszter LakatosRichard Sever @richardsever.bsky.social · 10/11/2024Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...connect.biorxiv.orgbioRxiv expands on Mastodon and BlueskybioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution 6361286
Reposted by Eszter LakatosTrevor Graham @trevorgraham.bsky.social · 28/11/2024We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfundedfindaphd.com 03328
Reposted by Eszter LakatosParmvir K Bahia @parmvir.com · 26/11/2024I suppose now is a good time to introduce #BiologyInNumbers, a #SciComm podcast I have the pleasure of directing, producing & hosting. Thought up by then-President Heiko Enderling, it's a means to learn about @smbmathbiology.bsky.social and research from its members and the wider #mathBio community. 075
Reposted by Eszter LakatosLena Boehme @lenamboehme.bsky.social · 21/11/2024Couldn't wish for a better BlueSky debut post: Our spatial atlas of the developing thymus is now published in Nature! 🥳 www.nature.com/articles/s41... Also check out the other papers in the new Human Cell Atlas collection: www.nature.com/collections/... #singlecell #spatial #multiomicsnature.comA spatial human thymus cell atlas mapped to a continuous tissue axis - NatureA quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in... 44610
Reposted by Eszter LakatosAndrew Krause @blindmath.bsky.social · 17/11/2024Join us in Durham for a fully-funded multidisciplinary PhD studying Metals, Microbes, Maths, and Metabolism! Please pass this along to interested candidates who are welcome to contact us directly. Both theoretical and/or experimental backgrounds welcome! iapetus2.ac.uk/studentships... 0158
Reposted by Eszter LakatosCarlo Maley @cmaley.bsky.social · 15/11/2024We just published a review of lessons farmers have learned for how to control pesticide resistance from evolving, and how to apply those to oncology to prevent cancers from evolving therapeutic resistance: bit.ly/48OfFdXbit.lyResistance Management for Cancer: Lessons from FarmersAbstract. One of the main reasons we have not been able to cure cancers is that treatments select for drug-resistant cells. Pest managers face similar challenges with pesticides selecting for pesticid... 1177
Reposted by Eszter LakatosDaniela Barillà @danielabarilla.bsky.social · 10/11/2024Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬 18271209
Eszter Lakatos @eszterlakatos.bsky.social · 29/01/2024Still 3 more weeks to apply for a PhD in computational biology/ cancer evolution! If you want to find out more about the many exciting positions in our department, we're doing a hybrid informal intro tomorrow: www.chalmers.se/en/current/c... (Non-Göteborg people can join on Zoom!) 001
Reposted by Eszter LakatosBenjamin Werner @benjaminwerner.bsky.social · 23/01/2024We are looking for two enthusisastic scientists to join our work on the evolution of ecDNAs in human cancers. Become part of the great @CancerGrand and join our team eDyNAmiC family. Happy to chat any time. Please contact me and ask for details! www.qmul.ac.uk/jobs/vacanci... 004
Eszter Lakatos @eszterlakatos.bsky.social · 08/01/2024Happy 2024 everyone! If your new year's resolution is to find a PhD (or help someone find a PhD) in computational biology, I've got just the thing 😉: 000
Eszter Lakatos @eszterlakatos.bsky.social · 21/12/2023❣️I am looking for a motivated PhD candidate to join me in creating new methods for unraveling cancer evolution @chalmersuniv❣️ Exciting research (if I may say so), great work atmosphere and superb employment benefits❗️ Find out more and spread the word: www.chalmers.se/en/about-cha... 131