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Kit Curtius

@yosoykit.bsky.social
958 followers 135 following 35 posts

Associate Professor at UCSD Medicine, Division of Biomedical Informatics. Researching cancer evolution and early detection. Check out our work at www.qcclab.com

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Kit Curtius @yosoykit.bsky.social · 17/02/2026
Our paper "Automated phenotyping with AI predicts future advanced neoplasia risk in colitis-associated low-grade dysplasia" out today in Clin Gastro Hep! Led by PhD student Brian Johnson-showcases power of LLMs to pull out relevant risk factors in huge EHR datasets www.cghjournal.org/article/S154...
cghjournal.org
Automated phenotyping with AI predicts future advanced neoplasia risk in colitis-associated low-grade dysplasia
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Reposted by Kit Curtius
dbmiucsd.bsky.social @dbmiucsd.bsky.social · 06/01/2026
DBMI is seeking applicants for our 2026 Postdoctoral Fellowships in Biomedical Informatics! Join our NIH NLM–funded fellowship. Eligibility: U.S. citizens, non-citizen nationals, or permanent residents (I-551). Apply: dbmi.ucsd.edu/education/nl...
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Kit Curtius @yosoykit.bsky.social · 19/09/2025
Our new paper is out today! PhD student Brian Johnson tour de force in applying and validating LLMs for phenotyping in massive EHR databases. Opens up many exciting opportunities for disease research using population-scale data #mathonco bmjopengastro.bmj.com/content/12/1...
bmjopengastro.bmj.com
Large language models for extracting histopathologic diagnoses of colorectal cancer and dysplasia from electronic health records
Objective Accurate data resources are essential for impactful medical research, but available structured datasets are often incomplete or inaccurate. Recent advances in open-weight large language mode...
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Kit Curtius @yosoykit.bsky.social · 15/07/2025
Gorgeous week in Edmonton, Alberta for #SMB2025 @smbmathbiology.bsky.social Fred Adler giving us the laughs we all need with his plenary on “Education, Bureaucracy and Corruption”
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Kit Curtius @yosoykit.bsky.social · 02/07/2025
Next up at #EBECancer25 summer school - hands-on digital pathology workshop with @mihaelaangelova.bsky.social @chandler-gatenbee.bsky.social
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Kit Curtius @yosoykit.bsky.social · 01/07/2025
here this week learning with all of our students at #EBECancer25 @eventswcs.bsky.social ! having a lot of Sudoku-type fun at our “grammar of somatic evolution” with tutor @afrankell.bsky.social
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Kit Curtius @yosoykit.bsky.social · 07/05/2025
That’s a wrap for QCC lab representation at #DDW2025! So fun to work with these people everyday. I’m also rocking yellow for osteogenesis imperfecta awareness day each May 6th #WishboneDay 💛
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Kit Curtius @yosoykit.bsky.social · 15/04/2025
Quite an earthquake today in SD! We're all good, but I loved watching the elephants' reaction to a natural threat at our beloved SD Zoo Safari Park 🐘
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Kit Curtius @yosoykit.bsky.social · 02/04/2025
Congrats to @cgucci.bsky.social on successfully defending her PhD on pi day! First PhD from our lab, so grateful for her dedication to our team and her supportive thesis committee (not pictured: Ludmil Alexandrov, sorry Ludmil!). Very excited to see all she does next... ☺️
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Kit Curtius @yosoykit.bsky.social · 14/02/2025
Our Division at UCSD Medicine is hiring postdocs in biomedical informatics on our T15 grant. Please apply if interested or share with others who might be! @ucsdmedschool.bsky.social @ucsandiego.bsky.social @ucsdhealth.bsky.social
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Kit Curtius @yosoykit.bsky.social · 14/02/2025
Applications are open for our Evolutionary Biology and Ecology of Cancer summer course at the Wellcome Genome Campus, UK! This is a great opportunity for early career scientists/trainees to get plugged into this field #mathonco @amyboddy.bsky.social @trevorgraham.bsky.social @afrankell.bsky.social
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Kit Curtius @yosoykit.bsky.social · 14/02/2025
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Kit Curtius @yosoykit.bsky.social · 30/01/2025
Today our study using copy number alterations (CNAs) from low-coverage WGS to predict FUTURE colorectal cancer in patients with IBD is published, details in thread! 1/5 gut.bmj.com/content/earl...
gut.bmj.com
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and dif...
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Kit Curtius @yosoykit.bsky.social · 18/01/2025
Our work on filtering host DNA from WGS data is also out today in @naturecomms.bsky.social! Congrats to first authors Caitlin Guccione and Lucas Patel - their methods were used in our new preprint and are freely available to use on your own data 🧬 www.nature.com/articles/s41...
nature.com
Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data - Nature Communications
Here, the authors apply novel pangenome indexes created from diverse human references to facilitate computationally efficient removal of host genetic information, preserving biological accuracy and pr...
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Kit Curtius @yosoykit.bsky.social · 17/01/2025
How do microbial communities assemble during precancer and cancer evolution? Excited to share our new preprint on modeling of microbial evolution in Barrett's esophagus and esophageal adenocarcinoma! 🦠 Led by PhD student Caitlin Guccione #barretts #mathonco more in 🧵 www.biorxiv.org/content/10.1...
biorxiv.org
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Kit Curtius @yosoykit.bsky.social · 10/01/2025
Devastated for those who lost everything in the horrible LA fires. Please send me any links to boost here to help those who need to rebuild <3
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Kit Curtius @yosoykit.bsky.social · 06/12/2024
So cool to see this go to an amazing mathematical biologist, congrats!! And I’m honored to win the Leah Edelstein-Keshet prize this year from SMB @smbmathbiology.bsky.social can’t wait for Edmonton, Canada next year 🌲🏔️ #mathonco
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Kit Curtius @yosoykit.bsky.social · 30/11/2024
Thankful this Thanksgiving break for this scientific community refresh to share with! PhD student Brian Johnson led our new preprint up today on using LLMs for extracting diagnoses in large EHR data- extremely accurate + easy to use for (pre)cancer Dx, go Brian! www.medrxiv.org/content/10.1...
medrxiv.org
Large language models for extracting histopathologic diagnoses from electronic health records
Background & Aims Accurate data resources are essential for impactful medical research. To date, most large-scale studies have relied on structured sources, such as International Classification of Dis...
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