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Eftychis Frangedakis

@e-frangedakis.bsky.social
143 followers 204 following 15 posts

SynBryo Group @OIST, Japan synbryo.weebly.com Plant Synthetic Biology 🌱 - EvoDevo 🏺 - Chloroplast ☀️ - Hornworts 🦄

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Reposted by Eftychis Frangedakis
UCDavisPlants @ucdavisplants.bsky.social · 11/08/2026
🌱 From Food and Bioproducts Processing: Dragon fruit peel waste yielded stable red betalain pigments that colored gelatin without altering taste, offering a potential natural food dye. (Bruno Augusto Mattar Carciofi) ▶️ www.sciencedirect.com/science/arti... #PlantScience #AgEngineering
Graphical abstract showing process and value of pitaya peel powder as a source of betalains.
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Gulnara Tagirdzhanova @metalichen.bsky.social · 11/08/2026
Our study on giant transposons Starship 🚀🧬 in the genome of the lichen fungus Xanthoria is now out in @pnas.org! What did we find out about Starships in #lichen fungi? 👇Updated thread below 🖥️ 🧪 🦠 🧫 #SymbioSky 1/6 www.pnas.org/doi/10.1073/...
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Jim Haseloff @jimhaseloff.bsky.social · 11/08/2026
Some info about alternative LED panels for the DIY Midi Grow-pods - used for split NFT hydroponic culture of Marchantia. marchantia.org/midi-nft-gro...
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Reposted by Eftychis Frangedakis
JCarlos Villarreal @jcarlosvillarreal.bsky.social · 27/07/2026
5 (+?) independent plant lineages evolved to text the same bacteria for nitrogen. we just need to learn the language they're using. www.cell.com/trends/plant...
cell.com
Plant–cyanobacterial symbioses: mutualism with emerging translational possibilities
Engineering rhizobial–plant nitrogen fixation in crops is a major goal in plant synthetic biology. We propose expanding efforts to plant–cyanobacterial symbioses as an alternative path. Targeting the ...
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Eftychis Frangedakis @e-frangedakis.bsky.social · 11/08/2026
We are organising @oistedu.bsky.social an Engineering Biology Symposium, 16-18 November 2026. Join us! 🌏 For more information and registration (deadline August 31): www.oist.jp/events/plant...
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Andy Plackett @seedrevolutionlab.bsky.social · 04/08/2026
www.nature.com/articles/s41... It's been a long time coming, but delighted to say that the first major output from my Royal Society Fellowship is now published. 🙂 #PlantScience
nature.com
The post-fertilization archegonium gene network of seedless plants contributed to the origin of seeds - Nature Communications
The authors identify conserved gene networks across fern and angiosperm reproductive development, including between the sporophyte ovule and the fern gametophyte egg-chamber. Repurposing of this netwo...
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Ed Rybicki 🇿🇲🇿🇦🇬🇧🍷🚀 @edrybicki.bsky.social · 11/08/2026
Interesting stuff!! Live rabies virus vaccine for dog baits, and plant-made protein for other edible vaccines.
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Reposted by Eftychis Frangedakis
Ryo Yokoyama @yokoyama-ryo.bsky.social · 15/07/2026
The contribution and responses of mosses to the global carbon cycle: Trends in Plant Science www.cell.com/trends/plant...
cell.com
The contribution and responses of mosses to the global carbon cycle
The colonization of land by plants reshaped the global carbon cycle, with distinct functional contributions from different lineages. Mosses, a diverse group of nonvascular plants, inhabit environments...
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Reposted by Eftychis Frangedakis
Ryo Yokoyama @yokoyama-ryo.bsky.social · 17/07/2026
Nuclear PPR Proteins Mediate Rhythmic C‐To‐U Editing of Mitochondrial RNA in Maize and Rice onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Nuclear PPR Proteins Mediate Rhythmic C‐To‐U Editing of Mitochondrial RNA in Maize and Rice
PPR genes exhibit rhythmic expression in response to light conditions, and are related to rhythmic RNA editing of mitochondrial genes. These results suggest that PPR genes might integrate environment...
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Reposted by Eftychis Frangedakis
Ryo Yokoyama @yokoyama-ryo.bsky.social · 20/07/2026
Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification onlinelibrary.wiley.com/doi/10.1111/... @plantbiotechj.bsky.social
onlinelibrary.wiley.com
Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification
Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant-environment interactions and broad industrial applications. Although n....
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Reposted by Eftychis Frangedakis
Plant Biotechnology Journal @plantbiotechj.bsky.social · 22/07/2026
🌱 RESEARCH 🌱 RNA-Guided Engineering of the Chloroplast Genome Enabled by Plastid-Expressed Guide RNAs - Mirzaee, Best et al. 🔗 doi.org/10.1111/pbi.... #plantscience 🧪
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Plant Physiology @plantphys.bsky.social · 03/07/2026
NEWS & VIEWS: Absence of plastidic carbonic anhydrases affects plant growth but not photosynthesis (Anna Moseler) doi.org/10.1093/plph... #PlantScience @aspbofficial
doi.org
Absence of plastidic carbonic anhydrases affects plant growth but not photosynthesis
Carbonic anhydrases (CA) are present in archaea, bacteria, and eukaryotes and catalyze the interconversion of CO2 and H2O with bicarbonate (HCO3−) and prot
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Reposted by Eftychis Frangedakis
Jim Haseloff @jimhaseloff.bsky.social · 03/07/2026
Instructions for building the latest Mini-NFT hydroponics system for Marchantia. USB powered pod with self-contained media circulation and LED lighting. Based on GN1/6 kitchen vessel. Larger scale DIY hydroponic systems on the way. marchantia.org/mini-nft-hydroponics
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Ignacy Bonter @ignacybo.bsky.social · 03/07/2026
Happy to share some of the auxin Marchantia research we've been working on for a while with @fromani.bsky.social and @jimhaseloff.bsky.social. We confirm long standing suspicions that stem cells in Marchantia exist in an auxin concentration/signalling minimum, and potentially a cytokinin maximum.
biorxiv.org
Marchantia stem cell maintenance and re-establishment are controlled by MpPIN1-mediated auxin transport and ARF signalling
Meristem organization in land plants depends on coordinated auxin distribution, transport and response, yet how these processes are integrated during vegetative growth of the gametophyte of non-seed p...
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Reposted by Eftychis Frangedakis
OIST (Okinawa Institute of Science and Technology) @oistedu.bsky.social · 24/06/2026
OIST, NTT, and the MRI have been observing typhoons near Okinawa, gathering data that could improve intensity forecasting. Now, they’re expanding into the East China Sea to study linear rainbands via ocean water vapor - broadening severe weather prediction. www.oist.jp/news-center/...
oist.jp
NTT and OIST expand observations from typhoons to linear rainbands and launch water vapor monitoring in the East China Sea
Capturing water vapor inflows into Kyushu to improve forecast accuracy for linear rainbands
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Facundo Romani @fromani.bsky.social · 26/06/2026
Glad to see Anna's final PhD paper as a pre-print. Marchantia as a bioproduction chassis not only for markers but also for useful proteins. #PlantScience #SynBio www.biorxiv.org/content/10.6...
biorxiv.org
Marchantia polymorpha as a simple platform for plant-based production of functional nanobodies
Recombinant proteins have transformative potential in biomedicine, but their production is often costly and carries contamination risks. Plants offer an attractive alternative, with low growth costs a...
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Eftychis Frangedakis @e-frangedakis.bsky.social · 25/06/2026
Can Marchantia be engineered to produce nanobodies? Check out the answer from🧑‍🔬 Sze Wai Tse: www.biorxiv.org/content/10.6...
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Reposted by Eftychis Frangedakis
Gozde Demirer @prof-gozde.bsky.social · 19/06/2026
Targeted DNA insertion remains a major bottleneck in plant engineering. We developed an avian R2 retrotransposon as an efficient plant genome editor to precisely insert large DNA payloads at targeted sites: www.nature.com/articles/s41... Congratulations to @kimuchenje03.bsky.social and the team! 🧵👇
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Jill Harrison @jillharrison.bsky.social · 18/06/2026
Happy to celebrate the first of my former PhD student George Greiff’s first author papers from his funded PhD work in my lab today. Aiming to analyse CLAVATA/WOX interactions in Physco, a first step was to address PpWOX13LC function, which he found to suppress polysety. Moss photo: Des O’Callaghan
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George R. L. Greiff @ilichenmoss2.bsky.social · 19/06/2026
Happy to announce our study that has just been published from work done during my PhD at the University of Bristol working in Prof. Jill Harrison's lab. It's about WOX genes and sporophyte development in the model moss, Physcomitrium patens. Take a look 🧵👇
A wild-type shoot with a single apical sporophyte (left) beside a Ppwox13lc mutant with three sporophytes on the same shoot (right).
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Reposted by Eftychis Frangedakis
Current Biology @currentbiology.bsky.social · 12/06/2026
When a protist engulfed a cynaobacterium, Earth changed forever! @jandevries.bsky.social, @caeciliafkunz.bsky.social, @heche.bsky.social & colleagues review the origins and evolution of archaeoplastids, the lineage that arose from this event, including plants & co www.cell.com/current-biol...
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Jim Haseloff @jimhaseloff.bsky.social · 12/06/2026
Business end of a low cost DIY gene gun - powered by a sodastream CO2 canister with minipump-driven vacuum shroud. Microparticle load is contained in a 13mm filter holder on a stainless steel mesh - like John Finer's particle inflow design. Looking at efficiency improvements...
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Reposted by Eftychis Frangedakis
Rodrigo Reis @rodrigoreislab.com · 10/06/2026
Cool new T-DNA plasmid! Let's see how it gets adopted and common tools become available -- hope those will happen to some level at least www.biorxiv.org/content/10.6...
biorxiv.org
Rational design of T-DNA vectors enables predictable, single-copy integration in Arabidopsis thaliana
Agrobacterium-mediated transformation is the dominant method for plant transgenesis, yet it frequently produces multi-copy, structurally complex T-DNA insertions associated with transgene silencing, u...
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Reposted by Eftychis Frangedakis
James Lloyd 🧬 @jamespblloyd.bsky.social · 29/05/2026
New review out: The Promise of Synthetic Biology for Redesigning Plant Architecture Great to have worked on this with @suruchiroy.bsky.social and Gerad dos Santos! doi.org/10.3390/ijms...
doi.org
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Nick Desnoyer @nickdesnoyer.bsky.social · 08/06/2026
Genes for genetic painting in flowers now available on Addgene!: addgene.org/browse/artic...
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Plant Cell Atlas @plantcellatlas.bsky.social · 10/06/2026
PCA Members are excited to share our new paper, which outlines a roadmap for tracing the origins & diversification of cell types across green plants using single-cell technologies. From algae to angiosperms, we're entering a new era of comparative cell biology. bit.ly/4eAip2Q
bit.ly
A single-cell blueprint for cellular diversity in the Green Lineage
The Green Lineage (Viridiplantae) represents one of the most successful evolutionary radiations on Earth, with remarkable morphological diversity from…
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Facundo Romani @fromani.bsky.social · 22/05/2026
Another cool liverwort genome by Szövényi group. #PlantScience link.springer.com/article/10.1...
link.springer.com
Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes - Genome Biology
Background Sex chromosomes evolve from autosomes and are expected to be initially homomorphic, though they may become heteromorphic over time. In diploid systems, one sex chromosome often degenerates,...
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Jim Haseloff @jimhaseloff.bsky.social · 10/06/2026
For liverwort mavens, I've needed to shift our Marchantia resources to a new website (I've reached retirement from academia in Cambridge) - and the plant synthetic biology stuff has moved to www.haseloff-lab.info (Now have more time for DIY builds! Updates to come)
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The Plant Cell @theplantcell.bsky.social · 02/05/2026
The Marchantia polymorpha recombinase MpRAD51 is at the crossroads of morphogenesis and the DNA damage response (Elias Trujillo-Esquivel , José Luis Lorenzo-Manzanarez , et al) doi.org/10.1093/plce... #PlantScience @aspbofficial
doi.org
The Marchantia polymorpha recombinase MpRAD51 is at the crossroads of morphogenesis and the DNA damage response
MpRAD51 links homologous recombination–mediated DNA repair with morphogenesis, revealing an evolutionarily conserved role in maintaining genome stability a
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Gregor Mendel Institute of Molecular Plant Biology @gmivienna.bsky.social · 04/05/2026
New paper! A study from the Dolan lab at the GMI of the @oeaw.bsky.social has just been published in Current Biology. Read the publication titled "Antagonism between blue- and red-light signaling controls thallus flatness in Marchantia polymorpha" here: www.cell.com/current-biol...
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Facundo Romani @fromani.bsky.social · 04/05/2026
MpERF14/GEMMIFER paper now published in Current Biology. Congratulations Go and Yuki for leading such a nice piece of research. #PlantSciences www.sciencedirect.com/science/arti...
sciencedirect.com
Initiation of asexual reproduction by the AP2/ERF gene GEMMIFER in Marchantia polymorpha
Plants can propagate their own clones through asexual reproduction. Genetic and hormonal factors regulating asexual reproduction have begun to be eluc…
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Dolf Weijers @dolfweijers.bsky.social · 03/05/2026
We are very happy and proud to present a study led by @jorgehg.bsky.social (now PI in Madrid – keep an eye on him!) in our team @bic-wur.bsky.social. In this work, we discover how auxin-regulated ARF transcription factors learned to activate transcription. A 🧵…(1/17) www.biorxiv.org/content/10.6...
biorxiv.org
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Botany One @botany.one · 04/05/2026
Bryophytes May Repel Snails Without Contaminating Crops www.botany.one/bryophytes-m... Bryophytes may hold natural compounds that keep hungry snails away from crops while avoiding the broader risks of conventional chemical controls. #Botany #PlantScience
botany.one
Bryophytes May Repel Snails Without Contaminating Crops
Bryophytes may hold natural compounds that keep hungry snails away from crops while avoiding the broader risks of conventional chemical controls.
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Hiro Nakagami @grandpahiro.bsky.social · 04/05/2026
Nice new story from Yuki's lab @yukihirakawa.bsky.social "Initiation of asexual reproduction by the AP2/ERF gene GEMMIFER in Marchantia polymorpha" doi.org/10.1016/j.cu...
doi.org
Redirecting
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Keri Backus @keribackus.bsky.social · 03/05/2026
Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...
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Ivan Radin @radinbio.bsky.social · 29/04/2026
Morphogenesis of moss leaf-like organs through variations in deeply shared developmental principles | Science Advances www.science.org/doi/full/10....
science.org
Morphogenesis of moss leaf-like organs through variations in deeply shared developmental principles
Auxin modulates a conserved developmental program in moss phyllids by spatiotemporally controlling cell division and growth.
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Ryo Yokoyama @yokoyama-ryo.bsky.social · 30/04/2026
Hornwort pyrenoids: a terrestrial exception with engineering lessons academic.oup.com/plphys/artic... @plantphys.bsky.social
academic.oup.com
Hornwort pyrenoids: a terrestrial exception with engineering lessons
Abstract. Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) underpins nearly all primary production yet remains a slow, error-prone enzyme because
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Ryo Yokoyama @yokoyama-ryo.bsky.social · 30/04/2026
Derlin-like proteins are essential for the function of Euglena gracilis chloroplasts academic.oup.com/plphys/artic... @plantphys.bsky.social
academic.oup.com
Derlin-like proteins are essential for the function of Euglena gracilis chloroplasts
Membrane pseudoproteases sustain chloroplast function in Euglena and reveal an unexpected protein import system, highlighting convergent evolution in cellu
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Trends in Plant Science @cp-trendsplantsci.bsky.social · 30/04/2026
Microneedle-assisted molecular delivery in plants #plantscience
dlvr.it
Microneedle-assisted molecular delivery in plants
Traditional agricultural delivery methods, such as foliar spray and soil application, suffer from low uptake efficiency, environmental contamination, and short-term effects, whereas nanoparticle-mediated delivery platforms face issues of stability, cytotoxicity, and regulatory concerns. Recently, microneedle (MN) technology has emerged as a promising alternative for precise, minimally invasive delivery of agrochemicals and biomolecules. In this opinion article, we explore the evolution of MN-based delivery systems in agriculture. We discuss the structure–function relationships of MNs (solid, hollow, dissolving, and coated MNs) and highlight their applications in nutrient delivery, pathogen control, and genome editing for plants. We conclude with challenges and future directions for integrating MNs into precision agriculture to improve crop productivity, sustainability, and genetic manipulation.
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Maddy Seale @maddyseale.bsky.social · 21/11/2025
And now we have Arabidopsis plants with 8 chromosomes instead of 10 and no obvious phenotypic differences, this week in @science.org #PlantScience Paper here: www.science.org/doi/10.1126/... Perspective here: www.science.org/doi/10.1126/...
science.org
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis
The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...
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Vincent CASTRIC @vincentcastric.bsky.social · 29/04/2026
Ever wondered what makes some alleles dominant (A) and others recessive (a) ? In our new paper, we explored how a series of recently discovered "dominance modifiers", genetic elements that have long remained elusive, achieve their regulatory function. journals.plos.org/plosgenetics...
journals.plos.org
Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways
Author summary Many plants avoid self-fertilization through a system of self-incompatibility, which allows them to recognize and reject their own pollen. In plants like those in the Arabidopsis family...
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Chenxin Li, PhD @chenxinli2.bsky.social · 30/04/2026
Reading science: wow that’s awesome. Reading news: wow that’s awful WTF
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Trends in Plant Science @cp-trendsplantsci.bsky.social · 29/04/2026
Bryophytes: natural incubators of new gene evolution #plantscience
dlvr.it
Bryophytes: natural incubators of new gene evolution
De novo gene origination from noncoding regions is a major source of genetic innovation. Dong et al. [1] (Nat. Genet. 2025; 57:2562–2569) reveal that bryophytes harbor an exceptionally high abundance of such genes, establishing them as a new and key system for studying the mechanisms and evolutionary consequences of new gene emergence in plants.
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bbsbryology.bsky.social @bbsbryology.bsky.social · 11/04/2025
My son sent this picture of a sign at the Temple of Saiho-ji in Kyoto. Makes a nice change from "Keep off the Grass".
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Ralf Reski @reskilab.bsky.social · 29/04/2026
Moss Produces Human Collagen for Skincare Unlike bacteria or yeast, #moss can produce large polypeptides of human #collagen along with the post-translational modifications that make it stable and bioactive. And it's #vegan. www.the-scientist.com/moss-produce...
the-scientist.com
Moss Produces Human Collagen for Skincare | The Scientist
Unlike bacteria or yeast, moss can produce large polypeptides of human collagen along with the post-translational modifications that make it stable and bioactive.
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Tamara Hernández-Verdeja @tamara-hverdeja.bsky.social · 29/04/2026
Very happy this work from my time in @marjorielundgren.bsky.social lab is out. @lancasterplantbio.bsky.social
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James Lloyd 🧬 @jamespblloyd.bsky.social · 29/04/2026
I am super excited to announce that I am recruiting a new post-doc to join my team at UWA & @plants4space.bsky.social to work on plant synthetic biology, with a focus on genome engineering. If you are interested, please apply or reach out to me. external.jobs.uwa.edu.au/cw/en/job/52...
external.jobs.uwa.edu.au
Prospective staff : Jobs at UWA : The University Of Western Australia
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James Lloyd 🧬 @jamespblloyd.bsky.social · 25/04/2026
Indeed, science and society progress because of neurodiversity, not in-spite of it. A dyslexic here. I still struggle today, but it’s got easier. But the prejudice of some people is still toxic.
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Yasin Dagdas @plantophagy.bsky.social · 25/04/2026
humanity has always been moved forward by people who think differently www.theguardian.com/commentisfre...
theguardian.com
Dyslexic thinking made me the scientist I am today. If we could harness its power, imagine what could be possible | Maggie Aderin
Progress has always been made by people who think differently. Neurodiversity helps us think outside the box – and when we do, the sky’s the limit, says space scientist Maggie Aderin
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Sebastian S. Cocioba @atinygreencell.bsky.social · 24/04/2026
What a cool way to have students interrogate Ai slop while learning actual science.
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