iiinova — where your digital self keeps evolving

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Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 28/08/2026

I am delighted to announce that The Department of Human Genetics at the University of Utah is continuing a multi-year recruiting initiative for multiple tenure-track faculty positions at the rank of Assistant Professor. Please share and consider applying! utah.peopleadmin.com/postings/208...

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Peter Ly @peterlylab.bsky.social · 19/05/2026

Excited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...

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Jorge Trojanowski @jorgetrojanowski.bsky.social · 27/04/2026

1/ ProPER - Our novel ligation-free proximity detection method for efficient multiplexed imaging of molecular interactions in situ. Among other things we use it to image the life cycle of RNA molecules and resolve differential kinetics of gene expression steps. New preprint: doi.org/10.64898/202...

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Devin Schweppe @dschweppe.bsky.social · 06/05/2026

With a few days since it's been out @keribackus.bsky.social @oligopain.bsky.social and I wanted to highlight a few of our favorite aspects of POCA for photocatalytic proximity labeling of DNA, RNA or proteins. (1) POCA builds on standard in situ hybridization and immunofluorescence workflows.

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Devin Schweppe @dschweppe.bsky.social · 03/05/2026

Excited to see this collaborative work with @oligopain.bsky.social and @keribackus.bsky.social out as a preprint now! Took a ton of work from a great team of scientists @uwgenome.bsky.social and #UCLA The imaging coupled with proteomics open our eyes to new aspects of subcellular organization!

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Keri Backus @keribackus.bsky.social · 03/05/2026

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...

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Brian Beliveau @oligopain.bsky.social · 22/04/2026

Excited to be attending this—still time to register, for those based in the area!

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Devin Schweppe @dschweppe.bsky.social · 07/04/2026

The next iteration of O-MAP targeting genomic loci is now at eLife!! DNA O-MAP enables proximity labeling at specific DNA loci took a ton of work from many lab members and collaborators, so it's really exciting to wrap up this paper with @oligopain.bsky.social! elifesciences.org/articles/102...

elifesciences.org

DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

DNA O-MAP enables proximity labeling at specific genomic loci in fixed cells using programmable oligonucleotides, revealing locus-proximal proteomes and chromatin interactions without genetic modifica...

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Sriram Pendyala @treependyala.bsky.social · 07/07/2025

🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇 1/9

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Anil Dash @anildash.com · 01/07/2025

This @zohrankmamdani.bsky.social video is absolutely INCREDIBLE. The numbers he cites, the strategy and results they produced — it’s the future. When have you heard *any* campaign talk about this, ever? (Video split in 2 to fit in Bluesky’s limits)

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Dave Shechner @shechnerlab.bsky.social · 30/06/2025

Hello! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @cp-cellreports.bsky.social, @mardakheh.bsky.social and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit! tinyurl.com/ydn6e3ac

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Ian L Morgan @ianlmorgan.bsky.social · 20/06/2025

Jay, please stop gaslighting early career researchers.

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Guy Nir @guynir.bsky.social · 16/06/2025

Our new preprint is out on bioRxiv! We show that restoring rigidity sensing via Tpm2.1 is not enough to trigger anoikis in cancer cells, thanks to compensatory AKT signaling and cell–cell adhesion. With Anat, Nehal, and in memory of Mike Sheetz. www.biorxiv.org/content/10.1...

biorxiv.org

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Jenna Norton @jenna-m-norton.bsky.social · 10/06/2025

Today, my NIH colleagues and I did something scary but really important. We spoke up about egregious harms we are seeing happen to research participants and public health through thoughtless and politicized policies at NIH. 🧵1/3 apnews.com/article/nih-...

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Kelley Harris @kelleyharris.bsky.social · 21/05/2025

. @pnas.org just published the final version of our manuscript on how generation time and effective population size interact to shape vertebrate germline mutation rates, led by Luke Zhu and Annabel Beichman: www.pnas.org/doi/10.1073/...

pnas.org

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 21/05/2025

The fantastically successful NIGMS MIRA R35 "expired" on May 17, after the most recent deadline--these removals are the most aggressive attack on American science in the current series of devastating actions 🧪

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Harmit Singh Malik @harmitmalik.bsky.social · 17/05/2025

🤩 And this is why hate will never win.

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Michael Baym @baym.lol · 14/05/2025

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

A screenshot of the termination notice showing "Outstanding Investigator Grants"

A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted

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Max Kozlov @maxkozlov.bsky.social · 06/05/2025

With NIH director Jayanta Bhattacharya dismissing my reporting as "false" and "spreading rumors" hours before releasing a policy that confirmed said "rumors," I feel compelled to respond. Here's an inside look into how this story was reported. It was a weird one. 🧵 www.nature.com/articles/d41...

On a Nature news article reporting that NIH planned to suspend subawards for foreign collaborations:
“No, that’s false. There’s going to be a policy on tracking subawards. The NIH and the government should be able to see where the money’s going.”

“I’m really uncomfortable with this conversation, because you’re like, actually spreading rumors that you don’t know anything about. … Nature also is spreading rumors. Halt foreign collaborations, that’s not true.”

“We’re working on the policy, Jocelyn. You shouldn’t be reporting rumors. I know there’s leaks all over here, but the leaks don’t actually reflect what’s happening. Don’t write about rumors. It actually makes the things that you and I care about worse. Like it spreads panic.”

Later that day, NIH released a policy that halted future subawards to foreign scientists and said they will need to apply directly for money under a system still in development.

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Jeremy Berg @jeremymberg.bsky.social · 06/05/2025

As a follow-up to the Kaiser interview, here is my exchange with Dr. Bhattacharya starting Sunday evening... 1/n

A letter from Jeremy Berg to NIH Director Jayanta Bhattacharya about the need to award grants promptly.

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Senator Patty Murray @murray.senate.gov · 05/05/2025

THIS is what NIH funding means for real people, and why we can't lose it. I sat down with Emily & her daughter Charlie to discuss how NIH-funded clinical trials at Seattle Children's led to a cure for Charlie's cancer. This is why we have to speak up, this is who we're fighting for.

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Brian Beliveau @oligopain.bsky.social · 30/04/2025

This but for checking eRA Commons en.wikipedia.org/wiki/Kiss_an...

en.wikipedia.org

Kiss and cry - Wikipedia

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 24/04/2025

Hi, everyone! My name is Alex. I'm a microbiologist/cell biologist/biochemist, and I'm sharing some of my career biography today for #YoungScientistNetworking. 1/

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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

media.tenor.com

the word alert is in a purple circle

ALT: the word alert is in a purple circle

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Kate Starbird @katestarbird.bsky.social · 05/04/2025

Seattle protests.

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Jeremy Berg @jeremymberg.bsky.social · 04/04/2025

New lawsuit filed today in Massachusetts aginst NIH from many state Attorneys General First, plaintiffs seek relief for the unreasonable and intentional delays currently plaguing the grant-application process 1/n

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Life Science Alliance @lsajournal.org · 04/04/2025

Excited to see CellCycleNet featured by @LSAjournal! CellCycleNet is a new 3D deep learning model that enables cell cycle staging using only a nuclear stain (DAPI), achieving 95% classification accuracy @oligopain.bsky.social @uwgenome.bsky.social www.life-science-alliance.org/content/8/6/...

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John Wallingford @jbwallingford.bsky.social · 02/04/2025

Director of the Nat'l Institute of Child Health and Human Development (NICHD) was summarily dismissed yesterday. So here's your reminder that birth defects kill twice as many American kids as cancer. But there is no St. Jude's for birth defects. Only the NICHD. www.nature.com/articles/d41...

nature.com

‘One of the darkest days’: NIH purges agency leadership amid mass layoffs

In shock move, four institute directors at the US biomedical agency are removed from their posts.

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ACLU @aclu.org · 02/04/2025

BREAKING: We're suing the National Institutes of Health over their politically-motivated purge of research grants. This is an unlawful attack on scientific progress that puts lives at risk.

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Senator Patty Murray @murray.senate.gov · 02/04/2025

If the goal was to decimate U.S. leadership in biomedical innovation & fire scientists developing cutting-edge treatments—the Trump Administration is succeeding. Trump & Elon are setting America back decades, undercutting research to discover lifesaving cures. It's inexcusable.

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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 02/04/2025

Dr. Richard Youle was fired today. He is an eminent scientist who has done important work on brain diseases like dementia and Parkinson’s. Musk and Trump are stopping NIH research into cures, for diseases from cancer to Alzheimer’s. Americans did not vote for this.

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Mark Cuban @mcuban.bsky.social · 29/03/2025

Just in NIH grants, It looks like beautiful Iowa City, home of the U of Iowa, will lose $71m in funding. That's almost $1k per resident. And that's before all the other cuts to SSA, FDA, etc. Anyone in Iowa City that can offer more insight? scienceimpacts.org H/T to Prathima !

scienceimpacts.org

SCiMaP

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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 29/03/2025

These are training grants. 🚨 The Trump administration has launched a war on students and young people studying science. It’s a common thread. Trump is killing student fellowship grants at NIH and NSF, and is killing the NIH and CDC in-house fellows programs.

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Stand Up for Science! @standupforscience.net · 29/03/2025

We are excited to announce our official partnership with @indivisible.org for the National Day of Action on April 5th! Stand Up for Science says: HANDS OFF OUR SCIENCE! #standupforscience #handsoffourscience Find and register for an event near you: handsoff2025.com?utm_source=s...

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Liz Borkowski @lizborkowski.bsky.social · 29/03/2025

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

grants.nih.gov

NOT-OD-25-080: Rescission of the Final Scientific Integrity Policy of the National Institutes of Health

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Rescission of the Final Scientific Integrity Policy of the National Institutes of Health NOT-OD-25-080. OD

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Dan Diamond @ddiamond.bsky.social · 28/03/2025

See this chart for one stark example: NIH funding has dramatically slowed down. Grant awards are down *$3 billion* so far, compared to same time period last year I asked the White House to explain. “This is not a researcher entitlement program,” said an official, defending their new approach.

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Mark Chadbourn @chadbourn.bsky.social · 27/03/2025

Kseniia Petrova, a Russian scientist at Harvard Medical School, was detained at Logan Airport after returning from France and sent to an ICE detention in Louisiana, The Insider reports. A big critic of Putin and the war in Ukraine, she may now be deported to Russia.

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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 27/03/2025

A scientist in Marc Kirschner's lab

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Chris Hayes @chrislhayes.bsky.social · 26/03/2025

Unidentified men grabbing someone off the street and putting her in a car because she wrote an op-Ed. This as flatly authoritarian as anything we’ve seen in this country in a very long time.

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Celeste Ng @pronounced-ing.bsky.social · 26/03/2025

Boston folks--rally this evening to support the Tufts PhD student, here on a visa, nabbed off the street yesterday 👇👇👇

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Kaia Mattioli @kaiamattioli.bsky.social · 26/03/2025

our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell! key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity many are "negative regulators" & misexpressed in cancer www.sciencedirect.com/science/arti...

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Jeremy Berg @jeremymberg.bsky.social · 25/03/2025

The information I am receiving is consistent with the STAT story. The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women. 3/n

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Scott Shapiro @scottjshapiro.bsky.social · 24/03/2025

White House says no one will be fired over the Signal scandal because no one involved was trying to cure cancer.

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 24/03/2025

This is a disaster and its happening right now. Having spoken with some folks in Congress, this is a message they have not received--they are still back in Indirects and USAID (also important, BTW). Call Congress today unless you want ot lose colleagues one by one till all are gone

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