The immune signal SA triggers metabolic changes to activate SnRK1 while inhibiting TOR. These central metabolic kinases antagonistically phosphorylate the key immune regulator NPR1, thereby coupling cellular metabolic state to systemic acquired resistance.

Summary: This study presents a live-imaging platform for tracking individual plant protoplasts in culture, enabling analysis of cellular processes, signaling dynamics and developmental transitions.

Genetically encoded biosensors are central to plant cell biology, but low reporter signal can limit their use. Here, we developed modular intronised fluorophores to improve reporter output in transien...

A mechanistic basis for how the hormone salicylic acid promotes transcriptional activation during plant immune responses is described.

The abundance of mRNA sets a ceiling on a cell’s capacity to produce protein and carry out its functions. Here, we describe a pathological decline in absolute mRNA abundance that occurs in most cell t...

Croll lab at University of Neuchatel. The lab of Daniel Croll wants to understand how pathogens evolve to cause disease. For this, we mainly focus on major crop pathogens to unravel mechanisms of rapi...

A swarm of autonomous AI agents, self-identifying as OpenAI agents, used a small German volunteer wiki to save answers, coordinate live, and share sandbox bypasses. OpenAI noticed and said nothing.

Biomolecular condensates formed through phase separation have emerged as a central principle of cellular organization, enabling the dynamic regulation of gene expression, signaling, metabolism, and st...

The T7 bacteriophage deactivates bacterial defence systems through T7K phosphorylation of nearly all host and phage proteins during infection.

Closing date: Monday 21 September 2026, 23:59

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In roots, the endodermis controls nutrient entry by forming a barrier known as the Casparian strip. Yet how barrier-associated processes interface with systemic signaling remains unclear. Here, we sho...

The emergence of the eukaryotes coincided with the diversification of histone proteins and their post-translational modifications by enzymes that constitute the core of eukaryotic chromatin. Yet the e...

Agrobacterium-mediated transformation is the dominant method for plant transgenesis, yet it frequently produces multi-copy, structurally complex T-DNA insertions associated with transgene silencing, u...

Nature - Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding