The increasing global burden and geographic expansion of dengue, coupled with the absence of specific antiviral treatments, underscores the urgent need for safe, effective and accessible therapeutics ...

Ongoing outbreaks demonstrate the urgent need for a global pandemic deal, leaders say.

Haemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory state caused by pathological immune activation. HLH can be due to a primary genetic defect, but most adults and adolescents (age...

The physician and pharmacologist died on February 1st, aged 74

BMC Infectious Diseases - Nocardiosis is a rare opportunistic infection with high mortality and a tendency to relapse. The causative Nocardia spp. are filamentous Gram-positive aerobic bacteria....

Approximately half the worldwide population is at risk for dengue. No antiviral prophylaxis or treatment options are available. In a phase 2a, double-blind, randomized trial, we assigned healthy ad...

YouTube video by Dr. Glaucomflecken

Kyasanur Forest disease is a neglected tick-borne viral haemorrhagic fever endemic to India's Western Ghats, caused by the Kyasanur Forest disease virus, a flavivirus transmitted by Haemaphysalis spin...

Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

Over the past 2 decades, there has been an unprecedented increase in infectious diseases among individuals with substance use disorders (SUDs). These inclu

Dengue, caused by any one of four distinct virus serotypes, is the most rapidly spreading mosquito-borne viral disease worldwide. It is a primary arboviral infection with increasing global incidence, ...

The first discovery of Aedes aegypti eggs in the UK shows how climate change and global travel are helping mosquitoes that spread dengue and Zika expand northwards.

Surveillance and prediction of antibiotic resistance in Escherichia coli relies on curated databases of genes and mutations. We aimed to quantify the …

Aedes aegypti further adapted to life around humans when it arrived in the Americas, study of hundreds of mosquito genomes reveals

According to French health authorities, a total of 10 new episodes of arboviral transmission transmitted by Aedes albopictus have been identified in mainland France: 9 episodes of chikungunya and 1 of...

Novartis on Tuesday said it had received approval in Switzerland for Coartem Baby, which it said was the first drug to treat malaria in babies and young children.

Abstract. In 2017, the pharmaceutical company Eli Lilly announced it would stop manufacturing quinidine, the only Food and Drug Administration–approved tre

The World Health Organization (WHO) is seeking feedback on the TPP from experts in the industry, product developers, the scientific community, NTD programme personnel and clinicians currently involved...

Yellow fever breakthrough infections documented in literature are rare, and not necessarily more common 10 years or more after primary yellow fever vaccination. This finding suggests that a single dos...

Dr Xin Hui Chan’s research focuses on developing equitable therapies for high-threat infectious diseases. She combines clinical trials, evidence synthesis, and modelling to address neglected infections and improve global health outcomes.

Vertical transmission is an important contributor to HBV transmission in the WHO African region. Scaling up of hepatitis B birth dose vaccination and antiviral prophylaxis is urgently needed, which co...

Our data highlight the need to strengthen arbovirus surveillance systems for the early detection of emerging and re-emerging outbreaks, including investments to increase awareness of arbovirus infecti...

Background Tick-borne encephalitis virus (TBEV) is a flavivirus spread by ticks and can cause tick-borne encephalitis (TBE) in humans. Previously, TBE has been reported in returning travellers in the ...

A new study of Nipah virus survivors has raised hopes that a measles-style vaccine is within reach

An FDC of albendazole plus ivermectin has a similar safety profile but superior efficacy to albendazole alone against T trichiura infection and hookworms. These findings open opportunities for control...

We show serologic evidence of prior exposure to Crimean-Congo hemorrhagic fever virus among humans in northern Tanzania. Similar to other settings, our results suggest that exposure is closely linked ...

Having just completed a stint doing inpatient ID consults, I came away impressed with three things: Staph aureus remains the Ruler of Evil Invasive Pathogens in the hospital setting. You can “jinx” a ...

Spread of Antifungal-Resistant <em>Trichophyton indotineae</em>, United Kingdom, 2017–2024