iiinova — where your digital self keeps evolving

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Dr. Michael D. L. Johnson @copperbae.bsky.social · 13/02/2026

STEM Black History Facts 13/28 Otis Boykin improved electrical components used in pacemakers, increasing the reliability of lifesaving implantable medical devices.

biography.com

These Famous Black Inventors Probably Changed Your Life. Here’s What to Know About Their Creations.

Madam C.J. Walker, Mark Dean, and Patricia Bath are just a few Black inventors who have made life easier.

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Teresa Lee @snickclunk.bsky.social · 09/02/2026

🎉 LEE LAB PAPER ANNOUNCEMENT for this month's issue of #GENETICS! We're celebrating from both coasts, bc after defending her MS in 2024, Deepshi's now a biotech researcher in the Bay Area. tl;dr: nucleosome remodeling is necessary to repair germline DNA damage 🧬 academic.oup.com/genetics/art...

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MwahahahahahadScientist @mads100tist.bsky.social · 10/02/2026

I think that, like with art, papers offer an opportunity for you to tell the story your own way. Could another person research the same question? Yes. However, each person has the opportunity to do it and communicate it in their own way, and we must protect that 🧪

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Sherrilyn Ifill @sifill.bsky.social · 06/02/2026

Let’s make it viral folks. Thank you @histoftech.bsky.social.

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Gregg Gonsalves @gregggonsalves.bsky.social · 04/02/2026

So the question here is mis-specified. There is no "alternative" research funding in any way that would make American biomedical research whole for researchers to seek out. 1/ www.statnews.com/2026/02/03/p... via @statnews.com

statnews.com

We asked whether principal investigators have plans in place for how research can continue without them

Researchers must be mindful of unexpected events that may leave them incapacitated or unable to lead their research projects or labs.

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Sherrilyn Ifill @sifill.bsky.social · 04/02/2026

More attention here, please.

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Job Dekker @jobdekker.bsky.social · 03/02/2026

Terrific paper on a new chromosomal compartment where extensive loop extrusion isolates domains from other such domains

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Karolin Luger @nucleosomepolice.bsky.social · 02/02/2026

Unquestionably the result of combined effort from all current and former lab members, support from colleagues @CSU and @CU, and support from @hhmi-science.bsky.social and NIH over decades. A heartfelt 🙏 to my nominators and of course @vilcekfoundation.bsky.social. vilcek.org/prizes/prize...

vilcek.org

Karolin Luger - Vilcek Foundation

Karolin Luger's research led to the capture of a high resolution image of chromatin, resulting in the development of innovative drug treatments for diseases like cancer.

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Drug Monkey @drugmonkey.bsky.social · 10/01/2026

Everyone who tut-tuts co-workers concerned about their job and health insurance should probably include some info on their own household finances, retirement situation and health conditions, current and anticipated.

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Enhanced Genomics @enhancedgenomics.bsky.social · 06/01/2026

Join our virtual seminar! @sedonamurphy.bsky.social presents cutting-edge research on 3D genome organisation & epigenetic memory in development, moderated by @stefanschoenfelder.bsky.social 📅 Jan 8, 4pm UK 💻 Zoom Register: us02web.zoom.us/webinar/regi... #3DGenome #Epigenetics #ChromatinBiology

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Allison Gill @muellershewrote.com · 26/12/2025

Can someone please respond to Stephen Miller with this message from Frank Sinatra?

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Sherrilyn Ifill @sifill.bsky.social · 26/12/2025

Please folks. Learn the history.

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Agathe Chaigne @agathechaigne.bsky.social · 18/12/2025

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

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Job Dekker @jobdekker.bsky.social · 17/12/2025

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...

nature.com

An integrated view of the structure and function of the human 4D nucleome - Nature

The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...

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Harmit Singh Malik @harmitmalik.bsky.social · 13/12/2025

@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/

biorxiv.org

Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals

The Polycomb Repressive Complex 2 (PRC2) is an ancient, conserved chromatin-interacting complex that controls gene expression, facilitating differentiation and cellular identity during development. It...

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Christine Cucinotta @chrstne.bsky.social · 02/12/2025

coming up for air after long periods of major depression feels like whiplash. late to the horrible news of our loss of Zara Weinberg. at a loss for words but she was one of the most amazing people i’ve known. brilliant. empathetic. making a huge difference in the world. i will miss her terribly.

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Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 02/12/2025

Get bedder v0.1.8 and r𝗲𝗮𝗱 𝘁𝗵𝗲 𝗱𝗼𝗰𝘂𝗺𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻 here: github.com/quinlan-lab/... We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.

github.com

Release Release v0.1.8 · quinlan-lab/bedder-rs

Changes in v0.1.8 Downloads bedder-static-linux-x86_64: Static binary for Linux x86_64 (no dependencies required) bedder-static-macos-x86_64-python3.13: macOS x86_64 binary built with Python 3.13 ...

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Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 02/12/2025

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n

quinlanlab.org

Intro to Bedder – The Quinlan Lab

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Tina Termini @cterminiphd.bsky.social · 01/12/2025

Truly enjoyed writing this piece about recent discoveries by @bloodgenes.bsky.social and colleagues about how we can improve HSC expansion & gene editing by blocking ferroptosis! Our @natcellbio.nature.com N&V: rdcu.be/eR25t Associated article: tinyurl.com/msf9x8fn

rdcu.be

Blocking ferroptosis to expand human HSCs

Nature Cell Biology - Haematopoietic stem cells (HSCs) are used in a variety of cellular therapies, but our ability to support these cells ex vivo remains technically challenging. A new study...

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Robin Allshire 🇮🇪 🇪🇺✊🏿 ⬆️ Zak’s favourite nucleosome: K9me @allshire-lab.bsky.social · 24/11/2025

AI is good at needling people, had me in stitches following this thread!

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Christine Cucinotta @chrstne.bsky.social · 17/11/2025

the best thing ever is when the person you are writing a letter for makes calendar invites for you for the deadlines

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Eishi Noguchi @enog.bsky.social · 14/11/2025

The lab published a nice paper, so we celebrated at our Friday lab meeting 🎉 #Publication #Science #GraduateSchool #BiomedicalSciences #Timeless #Cancer #Research #Senescence

A hallway monitor displaying news about the publication and featuring photos of the students who contributed to the work.

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Christine Cucinotta @chrstne.bsky.social · 14/11/2025

i hate it here. this is awful in so many ways i dont even have the words

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Mark Copelovitch @mcopelov.bsky.social · 13/11/2025

Congrats again, everyone

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Shubhangi Sharma @shubhangish.bsky.social · 12/11/2025

Had an amazing time at the CSHL Genome Informatics 2025 conference! Presented my poster: “Investigating quiescence-specific roles of FUN30 in chromatin compaction” 🧬 @chrstne.bsky.social #GI2025 #Chromatin #Genomics #Quiescence

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Irina Bezsonova @irinabezsonova.bsky.social · 14/10/2025

This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 13 Prompt DRINK Pdb: 7BTW A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer. Cheers! Next: TRUNK Suggestions?

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Drug Monkey @drugmonkey.bsky.social · 05/11/2025

Roughly 900 PIs who will not be getting their award in FY2025. But also they will not have that money for FY2026, FY2027, FY2028 or FY2029. and *next* year, we will be adding some more applicants to this list even if by some miracle the NIH budget is the same.

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Drug Monkey @drugmonkey.bsky.social · 05/11/2025

and there it is. the absolutely massive change in R01s funded multi-year. our perceptions that the new mandate, sorry strong suggestion, has had a dramatic effect on forward funding and therefore success rates is validated.

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Drug Monkey @drugmonkey.bsky.social · 05/11/2025

And importantly, while a few years to settle out might seem no biggie, it sure as heck is a big deal to those PIs who have been on the job for just a few years and are looking at the tenure decision looming ahead.

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Binyam Mogessie ቢንያም ሞገሴ @binyammogessie.bsky.social · 04/11/2025

We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨ With @jiyeonleem.bsky.social and our team at Yale MCDB. Read: www.nature.com/articles/s43...

nature.com

A versatile cohesion manipulation system probes female reproductive age-related egg aneuploidy - Nature Aging

To study pathways that lead to aneuploidy during aging, the authors provide a system that enables cohesion protein depletion in mouse oocytes, mimicking effects that occur during aging. They uncover a...

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Anil Dash @anildash.com · 28/10/2025

Really positive sign that open source projects are standing up to do the right thing. Kudos to the Python folks: www.theregister.com/2025/10/27/p...

theregister.com

Python Foundation rejects $1.5M grant with no-DEI strings

: Foundation says it won't compromise policy of inclusivity even if that cash would've really helped

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FragileNucleosome @fnucleosome.bsky.social · 14/10/2025

👀Next Wednesday, Oct 22nd, at #FragileNucleosome seminar, we are excited to host @alicelaigle.bsky.social and @seungsookim.bsky.social to tell us about amazing work they are doing! 🗓️Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...

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Dr. Kat Napaaqtuk❄️ @napaaqtuk.bsky.social · 13/10/2025

I am seeing a lot of people reposting Lakota Man today bc it's Indigenous Peoples Day. A reminder that he is not well liked amongst many (most?) Natives on social media. Many of us blocked him a long time ago. Some of the reasons why are in this article. www.dailydot.com/irl/lakotama...

dailydot.com

Who is LakotaMan, the user behind one of the most popular Native American accounts on X?

John Martin is adored by white X users—but infamous among Native and Indigenous communities.

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The Allard lab @allard-lab-ucla.bsky.social · 10/10/2025

Beautiful, layered argument for the use of model organisms, especially small ones, in research. A must read!

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Anne Carpenter @drannecarpenter.bsky.social · 10/10/2025

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

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Juliet J. Fall @julietjfall.bsky.social · 10/10/2025

Nobel Peace Prize 2025: "The committee commended Machado as a “brave and committed champion of peace” who had kept “the flame of democracy burning during a growing darkness”. 🔥 www.theguardian.com/world/2025/o...

theguardian.com

Venezuelan politician María Corina Machado wins Nobel peace prize

Leader of country’s opposition receives award after scrutiny surrounding committee and comments by Donald Trump

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New York Attorney General Letitia James @newyorkstateag.bsky.social · 09/10/2025

This is nothing more than a continuation of the president’s desperate weaponization of our justice system. I am not fearful — I am fearless. We will fight these baseless charges aggressively, and my office will continue to fiercely protect New Yorkers and their rights..

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Black Microbiologists Assoc (Black In Micro) @blackinmicro.bsky.social · 09/10/2025

Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025

The summarised schedule of Black in Micro Week 2025, October 14-16. All times are in Eastern Standard Time. Mon 14: Pathways for Change. Welcome and Keynote Address 12pm. Marian Johnson-Thompson, PhD. Panel Discussion: Finding Black Spaces in STEM, 1:15-2:15 PM. Weds 15, Careers & Research: ECR Symposium 9-12 PM. Panel discussion: Navigating Careers in Microbiology 2-3 PM. Thurs 16, Community: Panel Discussion - Empowering Your Science 12-1:15 PM. Workshop: Science in Action

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Chenxin Li, PhD @chenxinli2.bsky.social · 09/10/2025

A lot of good answers in the comments section. It’s more important now to teach understanding (rather than just syntax). If the experimental design was inadequate, it doesn’t matter if the coding was perfect. If the interpretation was wrong, it doesn’t matter if the statistics were done right.

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The Intercept @theintercept.com · 09/10/2025

Republican Senators, with an assist from Sen. John Fetterman, voted down an attempt to block the Trump administration’s missile strikes on alleged Venezuelan drug boats. interc.pt/4o9CBur

A photo of Sen. John Fetterman, D-Pa., sits on the steps of the U.S. Capitol on Oct. 1, 2025, in Washington, overlaid with the headline, "Fetterman Is Sole Democrat to Vote Against Blocking Caribbean Drug Boat Attacks," and the DEK, "It was the first time members of Congress were put on record about whether they supported or opposed the president’s war in the Caribbean."

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 07/10/2025

"rather than articulating and defending these goals and processes, many parts of the scientific establishment seemed to be rushing to violate one of the first tenets of historian Timothy Snyder’s important book On Tyranny: Do not obey in advance." 🧪

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Jeremy Berg @jeremymberg.bsky.social · 07/10/2025

4/14

Early on, I was deeply troubled to learn that many grants awarded through NIH mechanisms related to “diversity” were slated for wholesale termination. I saw stunning reactions from many in the scientific establishment. Universities, scientific societies, and private funding agencies rapidly took down webpages with statements about the importance of diversity and representation in the scientific workforce, and some cancelled programs; others just remained silent or rebranded such programs with new language. I found this distressing because these programs are not motivated by vague “social justice” goals, but rather with specific objectives related to engaging scientific talent from across our nation, diversification of perspectives on research questions, and, in some cases, building capacity to understand and address health disparities.

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Jeremy Berg @jeremymberg.bsky.social · 07/10/2025

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14

jeremymberg.github.io

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AZ Faust @azfaust.bsky.social · 03/10/2025

5. I don't know that US will ever be a stable place for science again. I know that sounds nihilistic but the 50% of the country that voted for Trump is not going anywhere and they appear to be ok with blowing up the entire research infrastructure for shits and giggles.

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AZ Faust @azfaust.bsky.social · 03/10/2025

4. If you're looking for a postdoc and you're not looking outside of the US - what in the world are you thinking??? This is not a place to establish a stable science career at the moment.

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Drug Monkey @drugmonkey.bsky.social · 03/10/2025

Read. Again. And one more time. #NewPI

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