FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have broader implications fo...

A visual blog about science and tissue engineering. Based on live doodles/sketchnotes done during talks. Some with an abstract/writeup.

Author summary This study explores the interplay between biology and mechanics in tissue architecture, particularly the 3D organization of human colonic epithelial organoid. The experimental approach ...

Le projet de loi de finances 2025, adopté hier au Sénat, prévoit un coup de rabot conséquent sur le budget de la recherche et de l’enseignement supérieur, avec 630 millions d’euros d’économies. Ces re...

Mechanical forces are critical for virtually all fundamental biological processes, yet quantification of mechanical forces at the molecular scale in vivo remains challenging. Here, we present a new st...

This package allows the user to perform 2D Bayesian Force Inference in Matlab Reference: Experimental validation of force inference in epithelia from cell to tissue scale W. Kong, O. Loison, P. Shiva...

GloBIAS is thrilled to announce the pilot session of Call4Help – a unique opportunity for researchers and image analysis enthusiasts to receive personalized guidance on using cutting-edge image analys...

InnovInOnco, with its partner research laboratories and masters programs, brings together fundamental and translational research, life sciences, biophysics and nanomedicine in oncology.

The organizing committee, Sylvain Gabriele, Marine Luciano, Jorge Barrasa Fano, Yohalie Kalukula, Bart Smeets, Apeksha Shapeti, Hans Van Oosterwyck

Nuclear deformation by osmotic shock or necrosis activates the cytosolic phospholipase A2 (cPla2) nuclear shape sensing pathway, a key regulator of tissue inflammation and repair. Ca²⁺ and inner nucle...

Directed cell migration along gradients of extracellular matrix (ECM) density –a process called haptotaxis– plays a central role in morphogenesis, the immune response, and cancer invasion. It is commo...

Uroz et al. report that the distinct mechanical properties of brain vasculature versus parenchyma drive cancer cell migration through a talin-dependent mechanism, enabling vessel co-option and metasta...

Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...

Torrino et al. identify the mechanosensitive polyol pathway as a natural mediator of cytoplasmic and nuclear protein condensates through tightly controlled intracellular sorbitol accumulation. Extrace...

some useful function to get Label from ROIs and vice versa , and more! - BIOP/ijp-LaRoMe

In recent years, advances in cell segmentation techniques have played a critical role in the analysi

While manual segmentation and tracking of cells from microscopy images remain common practices in biological studies, our work demonstrates the inter- and intra-user variability that can arise from t...

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...