Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP-2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that....

Collagen IV is a major constituent of basement membranes and mutations in the genes COL4A1 and COL4A2 present clinically as a variable, multi-system d…

Engineered living materials (ELMs), which usually comprise bacteria, fungi, or animal cells entrapped in polymeric matrices, offer limitless possibili…

Living Therapeutic Materials (LTMs) are a promising alternative to polymeric drug carriers for long term release of biotherapeutics. LTMs contain livi…

The dynamic mechanical nature of extracellular matrices (ECMs) is crucial for the mechanosensitive regulation of cell fate. This is evident in patholo…

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...