Background Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC) and results from pathogenic germline variants affecting mismatch repair. The tissue microenvironment that ...

Joint chromatin accessibility and transcriptomic profiling of human and mouse pancreatic lymph nodes uncovers distinct features of CD4 T cells in T1D.

Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...

Viruses are in us. They're even part of us. Now researchers want to map the human virome

With falling vaccination rates and outbreaks that have caused more than 580 U.S. cases and at least one death, health experts expect hundreds or even thousands more to be infected in the coming months...

Nature Microbiology - In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.

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Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

Pathogenic <i>Enterobacter</i> species are of increasing clinical concern due to the multidrug-resistant nature of these bacteria, including resistance to carbapenem antibiotics. Our understanding of ...

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

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A podcast on the host defense systems that protect against disease

Bridge to Faculty Postdoctoral Research Associate in Microbiology and ImmunologyThe Department of Microbiology and Immunology (MI) at the University o...