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Patrick S. Mitchell

@psmitchej.bsky.social
1.3K followers 424 following 50 posts

HHMI Freeman Hrabowski Scholar and Assistant Professor in the Department of Microbiology at the University of Washington studying host-pathogen interactions in beautiful Seattle. (he/him). Opinions are my own and do not reflect those of my employer.

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Reposted by Patrick S. Mitchell
Carl T. Bergstrom @carlbergstrom.com · 29/05/2026
Of all the harm this administration has done to US science, today's proposed changes to the way federal grants are awarded and administered is the most damaging yet. The text of the federal register document is impenetrably tedious by design, so here's an excellent summary of what it says.
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Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 28/05/2026
The University of Washington Department of Microbiology seeks to hire an Assistant Professor, Tenure Track. apply.interfolio.com/185622 We're interested in mechanistic approaches to study physiology and/or pathogenesis of bacteria and viruses, as well as microbial community interactions.
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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HHMI @hhmi-science.bsky.social · 26/05/2026
You asked, we answered — this time for our united #FreemanHrabowski Scholars and #HannaGray Fellows programs. A warm welcome into who's eligible, how the programs connect, and more, from our very own Science Program team members Mary Bonds & Lucy Corcoran. Applications open 11/3! bit.ly/fhs26 🧪
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Patrick S. Mitchell @psmitchej.bsky.social · 25/05/2026
Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Patrick S. Mitchell @psmitchej.bsky.social · 31/01/2026
Very excited to be invited to this exciting meeting! See you in France in a few short months!
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Bella Rauch @rauchlab.bsky.social · 22/10/2025
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech. We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!! www.nature.com/articles/s41... Explainer 1/8
nature.com
Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion - Nature
The bacterial ubiquitin ligase NleL evades host defence mechanisms both by inhibiting pyroptosis and by preventing infected intestinal epithelial cells from being extruded into the lumen and expelled ...
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Matthew Cobb @matthewcobb.bsky.social · 07/09/2025
Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.
nytimes.com
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
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Tera Levin @teralevin.bsky.social · 05/08/2025
I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/ www.biorxiv.org/content/10.1...
biorxiv.org
Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium
Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...
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The Seattle Times @seattletimes-rss.bsky.social · 14/06/2025
Over 70K in Seattle denounce Trump at massive ‘No Kings’ rally
seattletimes.com
Over 70K in Seattle denounce Trump at massive ‘No Kings’ rally
Massive crowds gathered in Cal Anderson Park, aboard a state ferry and at the state Capitol to denounce the hard-line policies of President Donald Trump.
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Stand Up for Science! @standupforscience.net · 11/06/2025
What does 18,000+ brave signatories look like standing together in massive solidarity with the #NIH heroes of the historic Bethesda Declaration??... Find out by adding YOUR NAME to our #NIHLove letter here! - actionnetwork.org/forms/add-na... #StandUpForScience #BethesdaDeclaration #StopTrump
actionnetwork.org
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
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Patrick S. Mitchell @psmitchej.bsky.social · 14/06/2025
#nokings
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Ben Collins @bencollins.bsky.social · 14/06/2025
Especially if you're on the fence about it, protest today. Fascism is isolating and lonely. Its very goal is to make you feel like you're the only person unwilling to accept a cult of personality. On days like today you fully realize there are more of us than there are them. You will feel better.
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Carl T. Bergstrom @carlbergstrom.com · 06/06/2025
"Sources said the administration is specifically considering a full termination of federal grant funding for the University of California and California State University systems." Pure vandalism. This could never happen in a country with functioning checks and balances.
cnn.com
Trump preparing large-scale cancellation of federal funding for California, sources say | CNN Politics
The Trump administration is preparing to cancel a large swath of federal funding to California, an effort which could begin as soon as Friday, according to multiple sources.
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Graham Coop @gcbias.bsky.social · 07/06/2025
The university of California is a powerhouse of innovation, healthcare, and social mobility for California and the US.
Federal investment in UC research Federal funds are the university’s single most important source of support for research, accounting for more than half of UC’s total research awards.

Many of California’s leading industries grew from UC research, including biotechnology, computing, semiconductors, telecommunications and
agriculture.

Providing health care at UC University of California Health (UC Health) is one of the nation’s largest public academic health systems, serving
as a critical part of the California safety net.

UC trains approximately 36% of the medical residents in California
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ASM @asm.org · 02/05/2025
Together with leading science organizations, ASM filed an amicus brief calling for immediate restoration of NIH grants supporting early-career scientists. Read the press release: asm.org/press-releas...
asm.org
Four Leading Science Organizations File Amicus Brief Supporting Funding Restoration
ASM joined leading life science organizations in an amicus brief filed in support of a suit calling for immediate funding restoration.
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Senator Patty Murray @murray.senate.gov · 02/05/2025
NIH's work saves lives—& Trump is gutting it. Straight from D.C. I headed to Seattle Children's to hear from researchers & patients alike about the importance of NIH funding—it's not just about lines in a budget, it's about lifesaving discoveries. We ALL need to speak up to save it.
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Patrick S. Mitchell @psmitchej.bsky.social · 05/04/2025
#Seattle showed out for the #Handsoff rally. Truly heartening to see the local and national turnout. Keep fighting.
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Stand Up for Science! @standupforscience.net · 28/03/2025
🚨 Over 70 graduate programs in the biological and biomedical sciences have frozen or slashed admissions. The consequences are profound—how many brilliant minds are being shut out of research entirely? How much future discovery is being lost before it even begins? docs.google.com/spreadsheets...
docs.google.com
Graduate Reductions Across Biomedical Sciences (2025)
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The Conversation U.S. @us.theconversation.com · 28/03/2025
Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs
theconversation.com
Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs
The National Institutes of Health has been integral to scientific progress in treating countless human diseases. Without its support, patients will ultimately pay the price.
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Dan Diamond @ddiamond.bsky.social · 28/03/2025
See this chart for one stark example: NIH funding has dramatically slowed down. Grant awards are down *$3 billion* so far, compared to same time period last year I asked the White House to explain. “This is not a researcher entitlement program,” said an official, defending their new approach.
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Patrick S. Mitchell @psmitchej.bsky.social · 28/03/2025
Federal funding of biomedical research has been a remarkably successful partnership, with benefits that are so intertwined in our daily lives that they can be easy to take for granted. So what will we lose if the U.S. continues to defund research? theconversation.com/cuts-to-scie...
theconversation.com
Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs
The National Institutes of Health has been integral to scientific progress in treating countless human diseases. Without its support, patients will ultimately pay the price.
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Heran Darwin, PhD @heran.bsky.social · 18/03/2025
More important now than ever before: vilcek.org/prizes/vilce...
vilcek.org
Vilcek Prizes for Creative Promise - Vilcek Foundation
The Creative Promise Prizes are awarded to young immigrant professionals who have demonstrated outstanding achievement early in their careers.
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Jesse Niebaum @niebaumjc.bsky.social · 15/03/2025
I wrote an OpEd arguing against funding cuts to NIH and NSF and their devastating impact for the newspaper I grew up with, the Morning Sun, in Pittsburg, Kansas. Keep spreading the word, wherever you can. morningsun.net/stories/maki...
morningsun.net
Making the case for science - The Morning Sun
I am a research scientist at the Center for Mind and Brain at the University of California, Davis. Before that, I was a student in Pittsburg Community Schools: I started kindergarten at Lakeside and g...
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Nate Sherer @natesherer.bsky.social · 13/03/2025
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Journal of Experimental Medicine @jem.org · 13/03/2025
First authors Madeline Churchill and Ankit Pandeya @nkeet50.bsky.social from @rauchlab.bsky.social show that tuft cells, known for their role in anti-parasite defenses, can also contribute to anti-bacterial responses in the small intestine. rupress.org/jem/article/... #InfectiousDisease
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Bella Rauch @rauchlab.bsky.social · 13/03/2025
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science! Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
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Sherry Pagoto, PhD @drsherrypagoto.bsky.social · 12/03/2025
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...
forbes.com
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
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Lisa Jarvis @lisamjarvis.bsky.social · 12/03/2025
🧪 The attack on science could have a generational effect. We risk losing a wave of early-career researchers to these cuts. And biomedical science in the US will be less ambitious, less competitive & lead to fewer breakthroughs. So much is at stake. My latest for @opinion.bloomberg.com (🎁 link):
bloomberg.com
NIH Cuts Create a Lost Generation of Scientists
Trump administration attacks on the National Institutes of Health mean biomedical research will become less ambitious, less competitive and result in fewer breakthroughs.
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Patrick S. Mitchell @psmitchej.bsky.social · 12/03/2025
See below for an AMAZING opportunity to learn the science of mosquito neurobiology.
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Eliver Ghosn @eliverghosn.bsky.social · 09/03/2025
1/4 Today, I honor Dr. Lee Herzenberg, a renaissance woman and a pioneer. #InternationalWomensDay #WomenInScience #IWD I’ve been fortunate to be mentored by women at home and in science. I met Lee in 2004, and her mentorship profoundly influenced my career and values.
Lee Herzenberg playing guitar during her time in FranceLee Herzenberg in her lab at Stanford
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Katherine J. Wu @katherinejwu.com · 07/03/2025
if you've had an NIH grant terminated, I want to hear about it. Signal: katherinejwu.12
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Patrick S. Mitchell @psmitchej.bsky.social · 08/03/2025
www.seattletimes.com/seattle-news... #standupforscience Many, many thanks to all who attended, the speakers, and to the incredible @sufsseattle.bsky.social organizers!!!
seattletimes.com
Seattle scientists fight back against Trump cuts, disinformation
“No one is coming to save us from this,” said Abraham Flaxman, a professor at the University of Washington. “We’re going to have to save ourselves.”
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Jonathan Eisen @phylogenomics.bsky.social · 08/03/2025
Posting some links to articles about the Stand Up For Science rallies In the @nytimes.com "Science, Politics and Anxiety Mix at Rally Under Lincoln Memorial" www.nytimes.com/2025/03/08/s... #StandUpForScience
nytimes.com
Stand Up for Science Rally Sees Mix of Science, Politics and Anxiety
Thousands of protesters gathered in Washington for Stand Up for Science, a rally in response to President Trump’s federal-funding and job cuts.
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Justin Gill @justin-gill.bsky.social · 08/03/2025
My message to those that aim to sow distrust in science & healthcare: You picked the wrong group to dismiss and discount. We do not yield to misinformation and lies! #standupforscience2025 @sufsseattle.bsky.social @standupforscience.bsky.social
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Zen Faulkes @doctorzen.net · 06/03/2025
They can’t fire science. Tell your story: bit.ly/faces_of_science
They can’t fire science. Tell your story: bit.ly/faces_of_science
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Bella Rauch @rauchlab.bsky.social · 07/03/2025
@standupforscience.bsky.social great turnout in Oregon for #standupforscience2025 !!! Thanks to all the amazing speakers!!!
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Patrick S. Mitchell @psmitchej.bsky.social · 07/03/2025
Thank you @governorferguson.bsky.social for Standing Up for Science!!! #standupforscience @standupforscience.bsky.social
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Science Magazine @science.org · 07/03/2025
Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4
scim.ag
Thousands gather across U.S. in Stand Up for Science events
Scientists rally across the country in response to layoffs and funding cuts ordered by the Trump administration
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Patrick S. Mitchell @psmitchej.bsky.social · 07/03/2025
STAND UP SEATTLE!!!
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Patrick S. Mitchell @psmitchej.bsky.social · 07/03/2025
Joining colleagues and concerned citizens across the US and around the world today who are Standing Up For Science. Why? ✔️research creates cures ✔️science grows the economy ✔️for my colleagues, our trainees, and the future of research and healthcare ✔️because science is for everyone
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Stand Up for Science! @standupforscience.net · 07/03/2025
LIVE STREAM UP! m.twitch.tv/standupforsc...
image of the livestream
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Bella Rauch @rauchlab.bsky.social · 04/03/2025
@laurenrodda.bsky.social, @nicelab.bsky.social , @jnpruneda.bsky.social and I wrote an OpEd on the impacts of NIH cuts on Oregon: www.bizjournals.com/portland/new... It was signed by over 450 OHSU researchers! It’s unfortunately paywalled, DM me if you’d like a gift link or a pdf of it.
bizjournals.com
Opinion: Scientists on how NIH cuts will hurt all Oregonians. - Portland Business Journal
"These cuts will cripple biomedical research and drug development in the U.S. We should be investing more in science, not less."
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Bella Rauch @rauchlab.bsky.social · 01/03/2025
The study section I sit on (Innate Immunity B) will be rescheduled to April. Just putting this out there since folks have been getting no notifications about whats going on with their grants.
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Indivisible ❌👑 @indivisible.org · 01/03/2025
Trump and Musk are cutting off cancer research.
npr.org
NIH funding freeze stalls applications on $1.5 billion in medical research funds
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
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Patrick S. Mitchell @psmitchej.bsky.social · 28/02/2025
Hope to see you next week #Seattle. This isn't just for scientists. Science is for everyone. Biomedical research benefits everyone. @standupforscience.bsky.social March 7 12-3 PM Seattle Center
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Alexandria Ocasio-Cortez @aoc.bsky.social · 22/02/2025
It may not be cool or hip in some circles, but we legitimately do need a massive amount of people to run for office. Flood the school boards, councils, county seats, state legislatures, Congress, etc. Big changes at the top happen when the ground shifts at the bottom. And that can start now.
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Jeremy Berg @jeremymberg.bsky.social · 21/02/2025
New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n
nytimes.com
Trump Administration Stalls Scientific Research Despite Court Ruling (Gift Article)
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
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Jeremy Berg @jeremymberg.bsky.social · 22/02/2025
A US Senator Joins the Fray. Thank you @murray.senate.gov ! More of this, please! www.murray.senate.gov/senator-murr...
murray.senate.gov
Senator Murray Blasts Trump & Elon for Illegally Paralyzing Lifesaving Research Again, Threatening to Extinguish Ongoing and Groundbreaking Work - Senator Patty Murray
ICYMI: Murray Blasts Trump and Musk Decimating HHS, Risking Americans’ Health and Livelihoods Washington, D.C. — U.S. Senator Patty Murray (D-WA), Vice Chair of the Senate Appropriations Committee and...
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Patrick S. Mitchell @psmitchej.bsky.social · 21/02/2025
In light of policies to defund biomedical research, and with judicial hearings happening today, we hope to highlight the many ways biomedical research improves people's lives, and to convey how damaging the proposed cuts would be... not just for us researchers, but for everyone.
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Marion Pepper @marionpepper.bsky.social · 08/02/2025
I tell people all the time WHY I love being a scientist: I’m obsessed with creative problem solving that leads to discovery AND it helps humanity. I rarely talk about HOW science happens. My own brother didn’t know how I funded my lab. Science is under attack. Everyone needs to understand this👇
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