iiinova — where your digital self keeps evolving

Brotman Baty Institute @brotmanbaty.bsky.social · 26/08/2025

BBI's annual Long-Read Sequencing Symposium is set for Sept. 16th, 10 am to 4:30 pm; poster session - 11:45 to 12:50. Location is UW's Foege Hall South, 3720 15th Ave NE, Seattle. Visit Redcap for details/registration; registration ends Sept. 5 at 12 noon. redcap.iths.org/surveys/?s=8...

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Reposted by Brotman Baty Institute

Atlas of Variant Effects Alliance @varianteffect.bsky.social · 16/06/2025

We’ve got two exciting VESS speakers lined up for July 1 🤩 🎙️Daniel Zimmerman postdoc @pittdeptofmed.bsky.social 🎙️Frederik Filip Vinggaard Stæger @ffstaeger.bsky.social postdoc at Univ. of Copenhagen Info + Zoom link: varianteffect.org/seminar-series #Genetics #MedicalGenetics #FunctionalGenomics

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Brotman Baty Institute @brotmanbaty.bsky.social · 16/06/2025

POSTDOC ALERT: Applications now open for SeaBridge postdoc fellowship; opportunity to work on leading-edge biotech w/researchers at the Seattle Hub for Synthetic Biology. brotmanbaty.org/news/new-pos... @marionpepper.bsky.social @jshendure.bsky.social @coletrapnell.bsky.social

brotmanbaty.org

New Postdoc Fellowship Program Builds on Innovative SeattleHub Research | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 05/06/2025

Zachary Amador, left, scientist w/Seattle Hub for Synthetic Biology, explains to artist Ranger Liu an experiment using DNA - they are collaborating togther in the Fred Hutch SxAffold "encounter" this week among artists & scientists. @fredhutch.bsky.social @calliechappell.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 03/06/2025

Ranger Liu, artist & physicist working on a Ph.D. in Astronomy at UW, is working w/a SeattleHub researcher as part of SxAffold, the weeklong collaboration among scientists & artists at the Hutch. Photo by Connor O’Shaughnessy / Fred Hutch alleninstitute.org/division/sea... @fredhutch.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 02/06/2025

TOMORROW - June 3 - at 9 AM - The Variant Effects Seminar Series will feature Ben Li (U of Michigan) & Vahid Aslanzadeh (U of Edinburgh) Details: www.varianteffect.org/seminar-seri... @varianteffect.bsky.social @uwmedicine.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 21/05/2025

Update from MSS 2025 in Barcelona: Dave Adams of Wellcome-Sanger presents on how genetic variation impacts cancer disease risk. Photo: Jonathan Frazer @jonnyfrazer.bsky.social @varianteffect.bsky.social @davidjadams.bsky.social @lindorfflarsen.bsky.social @sangerinstitute.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 20/05/2025

MSS 2025 is underway in Barcelona. Many thanks to Jonathan Frazier for posting updates regularly. Several BBI researchers are participating. @jonnyfrazer.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @muffley.bsky.social @shawnfayer.bsky.social #VariantEffect25

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Reposted by Brotman Baty Institute

Jonathan Frazer @jonnyfrazer.bsky.social · 20/05/2025

Let’s get this party started! Kicking off workshop 1 of #VariantEffect25 we have Albert Escobedo — From Fitness to Free Energy: Thermodynamic Modeling of Protein DMS Data for Accurate Genetic Prediction with MoCHI 🍡🧬

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Brotman Baty Institute @brotmanbaty.bsky.social · 16/05/2025

'Science can feel like magic. When you begin to understand how and why things work, it’s incredible.' Learn more about Katie Partington, an 'intellectually adventurous' promising young scientist in the lab of BBI's Dr. Doug Fowler. brotmanbaty.org/news/promisi... @dougfowler.bsky.social @hmc.edu

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Brotman Baty Institute @brotmanbaty.bsky.social · 15/05/2025

New paper by UW Medicine's Colin Pritchard clears up confusion on treating ‘passenger’ vs. ‘driver’ mutations in BRCA1 and 2 genes. Learn more. ascopubs.org/doi/pdf/10.1... @uwmedicine.bsky.social @ascocancer.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 14/05/2025

Hi Jonathan, we at BBI are looking forward to your posts next week from MSS 2025 from Barcelona. Cheers! @jonnyfrazer.bsky.social @varianteffect.bsky.social @bennibolo.bsky.social #VariantEffects25

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Brotman Baty Institute @brotmanbaty.bsky.social · 13/05/2025

HUGE congrats Lara Muffley - honored w/ UW Distinguished Staff Award for Collaboration - advancing world-class research on genetic variants on behalf of BBI brotmanbaty.org/news/bbis-la... @varianteffect.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @mehurles.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 08/05/2025

Are you or someone you know affected by Hemophilia B? BBI's Drs. Jill Johnsen & Doug Fowler have advanced genetic understandinng of the blood disorder. Learn more. brotmanbaty.org/news/new-mut... @uwmedicine.bsky.social @dougfowler.bsky.social @hemophilia.bsky.social

brotmanbaty.org

New Mutational Scanning Method Advances Genetic Understanding of Hemophilia B | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 02/05/2025

AI & Precision Medicine: The Stuart and Molly Sloan Precision Oncology Institute at Fred Hutch Cancer Center is hosting a symposium on AI, on Tuesday, May 20. Learn how AI is shaping treatment, diagnosis & prevention strategies for cancer. @fredhutch.bsky.social www.fredhutch.org/en/events/st...

fredhutch.org

Stuart and Molly Sloan Precision Oncology Institute AI Symposium

The Stuart and Molly Sloan Precision Oncology Institute is hosting an AI Symposium, which will feature a panel of local and national leaders in the field who will deliver talks and join in discussions...

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Brotman Baty Institute @brotmanbaty.bsky.social · 01/05/2025

Next up for the Variant Effects Seminar Series: Tuesday, 6 May, 9am (Pacific) w/ Timothy Tan (U of Illinois) & Mustafa Tekpinar (Van Yüzüncü Yıl University). Details: www.varianteffect.org/seminar-seri... @uwgenome.bsky.social @varianteffect.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 25/04/2025

Check out the newly refreshed Atlas of Variant Effects website: www.varianteffect.org/for A smoother & more intuitive experience. Kudos to the Wellcome Sanger Webdev team for their work @sangerinstitute.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 21/04/2025

One never knows the power and persuasion of elementary school teachers. Jonas ("Gus") Gustafson's fifth grade instructor 'allowed me to establish a life-long knack and passion for STEM.’ @uwmedicine.bsky.social @danrdanny.bsky.social brotmanbaty.org/news/promisi...

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Brotman Baty Institute @brotmanbaty.bsky.social · 16/04/2025

New study in Genome Biology: Guidelines for releasing a variant effect predictor - 'enhance personalized medicine & genetic disease understanding, aligning w/calls for standardized, rigorous VEP practices in genomic medicine' genomebiology.biomedcentral.com/articles/10.... @broadinstitute.org

genomebiology.biomedcentral.com

Guidelines for releasing a variant effect predictor - Genome Biology

Computational methods for assessing the likely impacts of mutations, known as variant effect predictors (VEPs), are widely used in the assessment and interpretation of human genetic variation, as well...

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Brotman Baty Institute @brotmanbaty.bsky.social · 14/04/2025

Looking Ahead: Mutational Scanning Symposium 2025, May 21-23, Barcelona, features Kresten Lindorff-Larsen addressing interface between variant effects & interpretation. Learn more: brotmanbaty.org/news/spotlig... @varianteffect.bsky.social @lindorfflarsen.bsky.social @bennibolo.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 09/04/2025

'The lives of cells, recorded:' Nature perspective reflects foundational principles of Seattle Hub & 'further(s) our understanding of cell decisions over time, given their cellular ancestry & past cell trajectories.' @naturegenet.bsky.social @jshendure.bsky.social brotmanbaty.org/news/nature-...

brotmanbaty.org

Nature Perspective Reflects Foundational Principles of Seattle Hub | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 31/03/2025

TOMORROW - 9 am (Pacific) Variant Effects Seminar - Presentations by Joyce Kang (Harvard-MIT) and Yiyun Rao (Penn State) @broadinstitute.org @pennstateuniv.bsky.social @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series

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Brotman Baty Institute @brotmanbaty.bsky.social · 27/03/2025

Mark your calendars now. The next variant effects seminar is Monday, 1 April, 9 am (Pacific), featuring Joyce Kang @harvard.edu @broadinstitute.org & Yiyun Rao @pennstateuniv.bsky.social. @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series

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Brotman Baty Institute @brotmanbaty.bsky.social · 17/03/2025

New Paper Advances Understanding how Genetic Variations Drive Disease: ‘We were able to resolve genetic & molecular basis of (the patient’s) condition, providing both her family & care team w/ answers to support her moving forward.’ @naturegenet.bsky.social brotmanbaty.org/news/paper-a...

brotmanbaty.org

Paper Advances Understanding how Genetic Variations Drive Disease: Q &A with BBI’s Dr. Andrew Stergachis | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 28/02/2025

NEXT TUESDAY: The March 4 session (10 am Pacific) of the Variant Effects Seminar Series will provide observations & insights from 3 engaging researchers: Shawn Fayer, Malvika Tejura & Zachary Walsh. Join: www.varianteffect.org/seminar-series @varianteffect.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 26/02/2025

Key deadline is almost upon us for the 2025 Mutational Scanning Symposium in Barcelona. Three 3 more days. March 1st - for abstract submissions and early bird registration rates. events.ibecbarcelona.eu/mutational-s... @varianteffect.bsky.social #VariantEffect25

events.ibecbarcelona.eu

MUTATIONAL SCANNING SYMPOSIUM

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Brotman Baty Institute @brotmanbaty.bsky.social · 20/02/2025

Updates on 2025 Mutational Scannning Symposium, May 21 to 23 in Barcelona: Insights and Observations from Wellcome Sanger's Dr. David Adams. @varianteffect.bsky.social @sangerinstitute.bsky.social brotmanbaty.org/news/q-and-a...

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Brotman Baty Institute @brotmanbaty.bsky.social · 10/02/2025

@science.org profile of @sudpinglay.bsky.social reveals his passion for genetics was ignited by undergrad course that was a 'sweatship for DNA.' Congrats Sud! www.science.org/content/arti...

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Brotman Baty Institute @brotmanbaty.bsky.social · 31/01/2025

Be sure to join the next Variant Effects Seminar Series, February 4 at 9 am (Pacific), hosted by @varianteffect.bsky.social See: www.varianteffect.org/seminar-series

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Brotman Baty Institute @brotmanbaty.bsky.social · 29/01/2025

The Chan Zuckerberg Initiative is awarding BBI researchers $1.5 million over two years to “democratize” access to synthetic DNA. We are envisoning complementary technologies that address shortcomings of current systems for manufacturing DNA. brotmanbaty.org/news/chan-zu... @sudpinglay.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 24/01/2025

REGISTER TODAY AND BOOK YOUR TRAVEL TO BARCELONA: Registration is now open for Eighth Annual Mutational Scanning Symposium, May 21st through 23rd in at the Barcelona Biomedical Research Park. Barcelona, Spain. brotmanbaty.org/news/registr... @varianteffect.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 13/01/2025

“It is the fundamental challenge of our time.” Learn more about that challenge in 'Understanding Genetic Variants in Context, published in eLife. Authors include several BBI faculty; Christine Queitsch, Ph.D., is a Corresponding Author. brotmanbaty.org/news/white-p...

brotmanbaty.org

White Paper Examines Molecular, Physiological, and Environmental Effects on Genetic Variants | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 08/01/2025

Looking back: 2024 was a memorable year for BBI. Here are several exceptional events and peer-reviewed papers from 2024. brotmanbaty.org/news/bbi-yea...

brotmanbaty.org

BBI Year in Review: 2024 | Brotman Baty Institute

BBI

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Brotman Baty Institute @brotmanbaty.bsky.social · 06/01/2025

@cziscience.bsky.social provides BBI $4.5 million to study genetic variants, including partnering w/patient organizations within CZI’s 'Rare As One' Project. brotmanbaty.org/news/chan-zu...

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Brotman Baty Institute @brotmanbaty.bsky.social · 17/12/2024

A dozen experts on computational biology to bioengineering to AI have been confirmed for the Eighth Annual Mutational Scanning Symposium, May 21st through 23rd in Barcelona, Spain. Registration opens January 20. Learn more: brotmanbaty.org/news/mss-202... @varianteffect.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 09/12/2024

‘Bringing together the best of large-scale science and philanthropy:' SeaHub Celebrates First Anniversary – Learn more about this extraordinary research collaboration brotmanbaty.org/news/seahub-... @cziscience.bsky.social @alleninstitute.bsky.social @jshendure.bsky.social @uwseattle.bsky.social

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Brotman Baty Institute @brotmanbaty.bsky.social · 25/11/2024

"It's a fundamentally new paradigm for how we measure biology over time" BBI Scientific Director Dr. Jay Shendure quoted in @nytimes.com article. "‘DNA Typewriters’ Can Record a Cell’s History" www.nytimes.com/2024/11/25/s...

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Brotman Baty Institute @brotmanbaty.bsky.social · 22/11/2024

Greetings Bluesky colleagues: The Brotman Baty Institute is honored to join this growing platform. Here's a link to our website for more information about our work exploring opportunities at the interface of basic science and precision medicine: brotmanbaty.org Looking foward to connecting....

brotmanbaty.org

BBI | Brotman Baty Institute

Precision medicine, genomics and data science have the potential to transform health care.

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