CERFA conecta a científicos españoles en Alemania, impulsa su comunidad y fomenta colaboración y oportunidades.

Speaker: Jing Chen Paper: Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesis (Immunity 2026) Moderator: Anna Salamero Boix (Open…

Speaker: Julia Belk Title: Microglia replacement during human aging Paper: Somatic mutations reveal the ontogeny of microglia in human aging (Nature 2026)

En este experimento, los calzoncillos funcionan como una especie de “sensor biológico” barato y visual para comparar cómo distintos usos y manejos del terreno afectan al suelo.

The authors apply ARACNe and metaVIPER to published scRNA-seq datasets to characterize pancreatic cancer subtypes, identifying six distinct cell states as well as their mechanistic determinants. Funct...

A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

This study identifies TIF1γ as a critical regulator of regulatory T cell stability during inflammation. By restraining β-catenin–TCF7 signaling, TIF1γ preserves Foxp3 expression, prevents inflammatory...

La capacidad del planeta para producir alimentos cambiará por el calentamiento, ¿qué zonas ganan y qué zonas pierden?

Ciudades como Barcelona y Palma de Mallorca experimentan brisas marinas hasta un 25 % más débiles que en la década de los 80 debido al cambio climático, lo que tiene consecuencias para su población.

The biological age of individual cell types can be evaluated using plasma proteomics, revealing diverse aging profiles across more than 40 cell types and links between the accelerated aging of specific cell types and disease.

A transcriptional regulatory map of pluripotent stem cells is generated by CRISPR screening.

Di Carlo and colleagues discuss technologies required to map and engineer the human cell–cell interactome and the therapeutic avenues such an atlas could unlock.

Liang et al. introduce PathPrism, a framework that converts whole-slide images into interpretable spatial biomarker spectra, establishing a transparent representation of tissue architecture. This representation enables transparent linear modeling of prognosis, molecular alterations, and treatment response with high performance, while transforming histopathology into a platform for interpretable discovery and perturbation-driven exploration.

2026 OBS Neuroimmunology Webinar Series Monthly on the Third Thursday at 12 PM ET Moderator: Jerry Lin (Massachusetts General Hospital) === #1: JANUARY 15, 12:00 PM ET / 6:00 PM CET Lymphoid gene expression...

Breast cancer brain metastases are a dismal condition, and it is unclear which patients benefit from immunotherapy. Jassowicz et al. multimodally characterize the cellular architecture of 156 human breast cancer brain metastases. They unravel inter-patient immune heterogeneity and discover and validate biomarkers for prognostically relevant immune landscapes.

In this review, Barreiro and colleagues synthesize molecular and cellular mechanisms of trained immunity across monocytes, tissue-resident macrophages, and HSPCs. They propose a unifying framework linking transcription factor activity, metabolic remodeling, and chromatin dynamics to explain how innate immune memory is established and maintained across cellular hierarchies.

Prinz and colleagues examine the distinct functions and repopulation properties of leptomeningeal and perivascular macrophages that mediate immune responses at brain boundaries.