A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

A mechanistic understanding of how regulatory T cell plasticity is controlled remains lacking. A study shows that TIF1γ modulates this plasticity by restraining β-catenin signaling.

This study identifies TIF1γ as a critical regulator of regulatory T cell stability during inflammation. By restraining β-catenin–TCF7 signaling, TIF1γ preserves Foxp3 expression, prevents inflammatory...

Nature, Published online: 02 June 2026; doi:10.1038/d41586-026-01766-4 Detonation of newly discovered ‘ruptoblasts’, found in flatworms, releases compounds that kill nearby cells in minutes.

Transforming growth factor β (TGF-β) is recognized as an anti-inflammatory cytokine that negatively affects effector CD8 T cells. However, its impact …

In this viewpoint, we hear from a cross section of women, across multiple research fields, discussing their science and the process of setting up a lab as

In this viewpoint, we hear from a cross section of women, across multiple research fields, discussing their science and the process of setting up a lab as

In this viewpoint, we hear from a cross section of women, across multiple research fields, discussing their science and the process of setting up a lab as