Reposted by Mahesh Binzer-PanchalbioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 20/08/2026nf-core/genomeqc: a best-practice pipeline for comparing genome and assembly quality www.biorxiv.org/content/10.64898/20… 011
Reposted by Mahesh Binzer-Panchalnf-core @nf-co.re · 04/08/2026Pipeline release! nf-core/seqsubmit v1.0.0 - 1.0.0! Please see the changelog: github.com/nf-core/seqsubmit/releas…github.comRelease 1.0.0 · nf-core/seqsubmitInitial release of nf-core/seqsubmit Added The pipeline supports four submission modes via dedicated workflows: mags — Metagenome Assembled Genomes submission (GENOMESUBMIT) bins — Metagenomic bin... 022
Reposted by Mahesh Binzer-PanchalNextflow @nextflow.io · 29/05/2026Become a Nextflow Ambassador in 2026!🌍 The ambassador program recognizes dedicated volunteers who contribute their time and expertise to foster collaboration & knowledge sharing across the Nextflow community. Applications close June 14, so don't wait! Apply now: hubs.la/Q04jlhr-0 011
Reposted by Mahesh Binzer-PanchalPhil Ewels @ewels.bsky.social · 13/05/2026My talk from the #NextflowSummit is on YouTube! youtu.be/LbA_d4oOpDQ I talked about my recent odyssey with AI-written software, including #RustQC, rewrites.bio, Trim Galore and a FastQC rust rewrite 👀 This was honestly one of my favourite talks to date. I hope it's interesting for folks 😊youtu.bePhil Ewels: Bioinformatics in the agentic age: Practical tips learnt from RustQC and rewrites.bioYouTube video by Nextflow 163
Reposted by Mahesh Binzer-PanchalKatharina Hoff @katharinahoff.bsky.social · 29/04/2026Post 1/2 Our new preprint is out! 🧬 We’ve extended #Tiberius for accurate ab initio gene prediction across the eukaryotic tree, including Plants, Fungi, Insects, and Diatoms. doi.org/10.64898/202...doi.org 11211
Reposted by Mahesh Binzer-PanchalSeqera @seqera.io · 23/04/2026In the run up to #NextflowSummit, we wanted to shoutout to all 143 of our #Nextflow Ambassadors.🌍 The Ambassadors have such a big impact growing the Nextflow community, mentoring new users, creating training materials, and pushing the boundaries of what's possible.👏 124
Reposted by Mahesh Binzer-PanchalNatalie Cooper @nhcooper123.bsky.social · 25/03/2026Hi all. I am very excited that after 6 years I finally got my phylogenetic comparative methods book and online exercises online. Feel free to use and share. The book is here: nhcooper123.github.io/pcm-primer/. Note that it is not finished, we had to abandon it before the sunk costs fallacy broke usnhcooper123.github.ioPhylogenetic Comparative MethodsPhylogenetic Comparative Methods 9288182
Reposted by Mahesh Binzer-PanchalJon Udell @jonudell.bsky.social · 12/03/2026Nothing requires us to cede autonomy to our freakishly talented LLM assistants. We direct their efforts, and they learn from us. As we do the work they wield tools on our behalf. We can, if we choose, learn from them how best to use those tools, even as we often delegate the use to them. 121
Mahesh Binzer-Panchal @arcane-mahesh.bsky.social · 10/03/2026I finally fixed a few things in my Nextflow daisy chaining proof of concept and added a couple others. github.com/mahesh-panch.... Thanks to the Seqera team for spotlighting it in a recent podcast. seqera.io/podcasts/epi...github.comGitHub - mahesh-panchal/nf-cascade: A proof of concept daisy-chaining Nextflow workflowsA proof of concept daisy-chaining Nextflow workflows - mahesh-panchal/nf-cascade 020
Reposted by Mahesh Binzer-Panchalphy_papers @phypapers.bsky.social · 28/02/2026OrthoGarden: a Pipeline for Propagating Phylogenetic Trees for Non-Model Organisms from Short Reads and de novo Genome Assemblies pubmed.ncbi.nlm.nih.gov/41755752 062
Reposted by Mahesh Binzer-PanchalWei Shen 沈 伟 @shenwei356.bsky.social · 27/02/2026Can't wait to release a 10-year-old birthday version for SeqKit! - 10 years - 2 papers, 3500 citations - 20 contributors - 40 subcommands - 880 commits - 500 issues - 685.5K Bioconda total downloads Thank you all, dear contributors and users! I'll keep maintaining it. github.com/shenwei356/s...github.comRelease SeqKit v2.13.0 (10-year-old birthday version) · shenwei356/seqkitChangelog SeqKit is 10 years old! SeqKit v2.13.0 - 2026-02-28 seqkit: add support for reading and writing LZ4 compression format. new command: seqkit sample2: improved seqkit sample by @stahiga.... 612735
Reposted by Mahesh Binzer-PanchalAnna Niehues @anna-niehues.bsky.social · 26/02/2026Keeping your research software metadata in sync across repositories and registries just got easier. We’ve developed a bidirectional bridge between GitHub and bio.tools, helping you keep metadata up to date automatically. Check out our BioHackrXiv preprint: doi.org/10.37044/osf...doi.orgOSF 041
Reposted by Mahesh Binzer-PanchalZamin Iqbal @zaminiqbal.bsky.social · 25/02/2026 @wytamma.bsky.social 's WASM tools have transformed my experience of teaching Python to first year undergraduate biologists this year. Since last year, I've been teaching ~400 undergrads how to code (functions, lists, dictionaries, loops) over (one hour intro lecture +) two 2-hour practicals. 1/n 36217
Reposted by Mahesh Binzer-PanchalBoas Pucker @bpucker.bsky.social · 25/02/2026Are you passionate about computational biology and the evolution of specialized plant metabolism? More details and contact information: www.izmb.uni-bonn.de/en/pbb/conta... #Bioinformatics #Genomics #ResearchInGermany @puckerlab.bsky.social 01310
Reposted by Mahesh Binzer-PanchalAshley Juavinett, PhD @ashleyjuavinett.bsky.social · 24/02/2026This paper started as an exchange here in late 2024 and evolved over the next year into a tidy set of recommendations for labs hoping to build more collaborative coding communities. 🎉 Would love to hear if any of these (really not so "simple") rules resonate with you, and what else you've tried. 01812
Reposted by Mahesh Binzer-PanchalJames Ferguson @psy-fer.bsky.social · 22/02/2026Building a new plotting library in pure Rust. Making themes and colourblind mode available on every plot type from day 1. What other accessibility options can I add? 162
Reposted by Mahesh Binzer-PanchalBF Francis Ouellette @bffo.bsky.social · 24/02/2026From @sciencebanshee.bsky.social @shen4brains.bsky.social @analog-ashley.bsky.social & colleagues in @plos.org #Computational #Biology | Ten simple rules for building a collaborative #coding #culture | #Education #Bioinformatics #PLOSCBTSR #OpenScience 🧬 🖥️ 🧪🔓 ⬇️ journals.plos.org/ploscompbiol...journals.plos.orgTen simple rules for building a collaborative coding culture 072
Reposted by Mahesh Binzer-PanchalStephen Turner @stephenturner.us · 23/02/2026Ten common misconceptions about Galaxy (and why they are wrong!) journals.plos.org/ploscompbiol... 154
Reposted by Mahesh Binzer-PanchalOpen Sustainable Technology @opensustaintech.bsky.social · 23/02/2026We welcome a new project to OpenSustain.tech #climate #sustainability #opensource #opensustain #openscience github.com/nextflow-io/...github.comGitHub - nextflow-io/nf-co2footprint: A Nextflow plugin to estimate the CO₂ footprint of pipeline runs.A Nextflow plugin to estimate the CO₂ footprint of pipeline runs. - nextflow-io/nf-co2footprint 021
Reposted by Mahesh Binzer-PanchalTitus Brown @titus.idyll.org · 22/02/2026Metax looks really nice for taxonomic profiling: www.biorxiv.org/content/10.6...biorxiv.org 0105
Reposted by Mahesh Binzer-PanchalTrish Greenhalgh @trishgreenhalgh.bsky.social · 21/02/2026American professors, who wants to come to Oxford for a year or two? Get in quick - deadline soon. www.balliol.ox.ac.uk/vacancy-geor...balliol.ox.ac.ukVacancy - George Eastman Visiting ProfessorshipVacancy - George Eastman Visiting Professorship The University invites expressions of interest in the George Eastman Visiting Professorship for the academic years 2026/2027 and 2027/2028, in an area 48083
Reposted by Mahesh Binzer-PanchalStephen Turner @stephenturner.us · 19/02/2026Interesting post on electricity and water use from AI agents from @simonpcouch.com: www.simonpcouch.com/blog/2026-01... 2194
Reposted by Mahesh Binzer-PanchalCamille Marchet ⚡ @camillemrcht.bsky.social · 19/02/2026Were you aware that these are available for the community: - an efficient fasta/q parser in Rust - a quick rolling hash library - a minimizer library All in Rust 🦀 1288
Reposted by Mahesh Binzer-PanchalTitus Brown @titus.idyll.org · 18/02/2026sketch directly from URLs (including esp GenBank ;) github.com/sourmash-bio...github.comGitHub - sourmash-bio/sourmash_plugin_directsketchContribute to sourmash-bio/sourmash_plugin_directsketch development by creating an account on GitHub. 171
Reposted by Mahesh Binzer-PanchalThomas Germain @thomasgermain.bsky.social · 18/02/2026I got a tip that all over the world, people are using a dead-simple hack to manipulate AI behavior. It turns out changing what AI tells other people can be as easy as writing a blog post *on your own website* I didn’t believe it, so I decided to test it myself www.bbc.com/future/artic...bbc.comI hacked ChatGPT and Google's AI – and it only took 20 minutesI found a way to make AI tell you lies – and I'm not the only one. 301971675
Reposted by Mahesh Binzer-PanchalBF Francis Ouellette @bffo.bsky.social · 18/02/2026From @stephenturner.us | Rubrics, Not Vibes: Consistency as a Feature in Peer Review with AI | 🧪 #AI #OpenScience #PeerReview #Grants #Publications #PairedEnds ⬇️ blog.stephenturner.us/p/rubrics-no...blog.stephenturner.usRubrics, Not Vibes: Consistency as a Feature in Peer Review with AIResponsibly using AI for a structured first pass manuscript / grant proposal review can reduce reviewer variance while keeping human judgment central. Bonus: a prompt I use for my own draft proposals. 053
Reposted by Mahesh Binzer-PanchalRob Patro @robp.bsky.social · 17/02/2026How would you design a *multithreaded*, *concurrent* & *dynamic* hash table if you are focused specifically on common k-mer workloads, where streaming query & insertion are common? Jamshed, Prashant and I explore this in kache-hash, a cache-friendly k-mer hash table! www.biorxiv.org/content/10.6...biorxiv.org 02013
Reposted by Mahesh Binzer-PanchalCat Hicks @grimalkina.bsky.social · 15/02/2026Key to efficient learning is realizing how we ACTUALLY learn, not just what FEELS like learning. I wrote a Claude Skill for some friends to help them think about this and they've liked it -- see Principles for some directions you could explore github.com/DrCatHicks/l...github.comGitHub - DrCatHicks/learning-opportunities: A Claude Code skill for deliberate skill development during AI-assisted codingA Claude Code skill for deliberate skill development during AI-assisted coding - DrCatHicks/learning-opportunities 925345
Reposted by Mahesh Binzer-PanchalELIXIR Europe @elixir-europe.org · 16/02/2026📣 BioHackathon 2026 will be held on 9-13 November 2026 in Barcelona, Spain 🇪🇸! Call for project proposals will open on 16 March and close on 15 April at midnight. More information on project proposal scopes: loom.ly/m6hEBcM Check the #BioHackEU25 highlights: loom.ly/AfKwtZAbiohackathon-europe.orgBioHackathon EuropeFind out about the 2026 BioHackathon Europe, where hackers get together to make life science research easier. 174
Reposted by Mahesh Binzer-PanchalRob Patro @robp.bsky.social · 15/02/2026I’ve written a post about my recent experiences (successes) with AI coding models; the experiences that caused me to re-evaluate my initial judgements, the surprise I had at what can be accomplished, & some fears I have about these tools. Discussion welcome! combine-lab.github.io/blog/2026/02...combine-lab.github.ioCOMBINE-lab - The skeptic’s guide to generative AI assisted codingAn easy-to-use, flexible website template for labs, with automatic citations, GitHub tag imports, pre-built components, and more. 85215
Reposted by Mahesh Binzer-PanchalSébastien Guizard @bioinformaticus.bsky.social · 12/02/2026I'm using #Nexflow almost daily. It is such a time saviour for analysis by suppressing job management. Here is the Hello-Nextflow playlist for those who want to join the Nexflow family. youtube.com/playlist?lis... 001
Reposted by Mahesh Binzer-PanchalJeffrey Ross-Ibarra @jrossibarra.bsky.social · 09/02/2026Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!docs.google.comDavis Summer Population Genomics ProgramWant to learn population genetics? Please fill out this form to indicate your potential interest in a 2-week intensive online summer population genetics course taught by Jeffrey Ross-Ibarra and Graham... 6140168
Reposted by Mahesh Binzer-PanchalDr Elodie Chabrol @eloscicomm.bsky.social · 11/02/2026🔬 C'est la Journée des femmes et filles de science ! #FemmesEnSciences #11février Envie de découvrir (ou faire découvrir) des femmes scientifiques ? J'ai rassemblé plein de ressources ici ⬇️ www.linkedin.com/pulse/envie-... Et mon starter pack de chercheuses sur bluesky go.bsky.app/TBEzKC 06046
Reposted by Mahesh Binzer-PanchalERGA - European Reference Genome Atlas @ergabiodiv.bsky.social · 21/01/2026#ERGAReads | On the path to reference genomes for all biodiversity: laboratory protocols & lessons learned from processing over 2,000 species in the Sanger Tree of Life 🔗 academic.oup.com/gigascience/... @sangerinstitute.bsky.social @ebpgenome.bsky.socialacademic.oup.comOn the path to reference genomes for all biodiversity: laboratory protocols and lessons learned from processing over 2,000 species in the Sanger Tree of LifeAbstract. Since its inception in 2019, the Tree of Life programme at the Wellcome Sanger Institute has released high-quality, chromosomally resolved refere 084
Reposted by Mahesh Binzer-PanchalNextflow @nextflow.io · 20/01/2026Nextflow Ambassador Nour Mahfel shares her journey from complete beginner to @nf-co.re contributor with support from @seqera.io. Learn how she shifted her mindset to think in dataflow, upstream modules, and embrace working in the open.📚 hubs.la/Q03_gcw_0 032
Reposted by Mahesh Binzer-Panchalnf-core @nf-co.re · 17/01/2026New blog post! Running nf-core pipelines on ARM nf-co.re/blog/2026/arm-pipelines 033
Reposted by Mahesh Binzer-PanchalStephen Turner @stephenturner.us · 18/01/2026nf-core/crisprseq: a versatile pipeline for comprehensive analysis of CRISPR gene editing and screening assays academic.oup.com/nargab/artic... 🧬🖥️🧪 github.com/nf-core/cris... 052
Reposted by Mahesh Binzer-PanchalHeng Li @lh3lh3.bsky.social · 06/01/2026Now published in Algorithms for Molecular Biology: link.springer.com/article/10.1.... Key message: a tiny CNN model with 7k parameters can capture main splice signals across vertebrates+insect and halves the minimap2 & miniprot junction error rate. I always use this new feature now. 15920
Reposted by Mahesh Binzer-PanchalCATALYST Project @catalyst-reproducibility.eu · 18/12/2025🎉 The full TIER2 Reproducibility Training Course is now available on OpenPlato. 💡 It provides researchers, publishers, and funders with both theoretical foundations and practical tools to support reproducible research practices. 🔎 Explore it here: openplato.eu/login/index.... 043
Reposted by Mahesh Binzer-Panchalrogier kievit @rogierk.bsky.social · 18/12/2025I've used Lavaan almost every (work)day for 15 years, but this open source labour of love has never received proper institutional support. I'm delighted to be a small part of an 1.5M OpenScienceNL award, led by Jorgensen, to completely revamp and futureproof Lavaan www.openscience.nl/en/news/45-p... 1026762
Reposted by Mahesh Binzer-PanchalJames Fellows Yates @jfy133.genomic.social.ap.brid.gy · 11/12/2025🎉 Huge shout out to everyone who instructed and participated in yesterday's online Meta-*omics #Nextflow Pipeline Community Exhibition Day! 🧑🏫 Over 9 hours, we had 15 different pipelines demo'd by their lead developers, and giving an international cohort of […] [Original post on genomic.social] 152
Reposted by Mahesh Binzer-PanchalMile Sikic @msikic.bsky.social · 11/12/2025I’m recruiting a postdoc to work on algorithms for cancer genome reconstruction. We have access to a rich set of tumour samples sequenced across multiple technologies. If interested, feel free to DM. Please share. 01312
Reposted by Mahesh Binzer-PanchalDuke University School of Medicine @dukemedschool.bsky.social · 04/12/2025Researchers say they’ve uncovered a key pathway behind age-related muscle loss. The surprising part: exercise helps reset the cellular system that keeps muscles young. 🔗 Read more: medschool.duke.edu/news/why-muscles… #AcademicSky #MedSky 092
Reposted by Mahesh Binzer-PanchalHasindu Gamaarachchi @hasindu2008.bsky.social · 04/12/2025Cornetto v0.2.0 is now released for using programmable selective nanopore sequencing for genome assembly. GitHub: github.com/hasindu2008/... Paper: nature.com/articles/s41... Datasets: hasindu2008.github.io/cornetto/doc... ... and a banner made by Ira Deveson referring to ‘no boring bits’. 1218
Reposted by Mahesh Binzer-PanchalWellcome Sanger Institute @sangerinstitute.bsky.social · 04/12/2025The Sanger Prize 2026 is open for applications. A fully funded three-month placement for undergraduate students from low and middle-income countries. 🔗 Apply now: www.sanger.ac.uk/about/study/... 📅 The closing date for applications: 9th January 2026 at 5pm GMTlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 066
Reposted by Mahesh Binzer-Panchalnf-core @nf-co.re · 03/12/2025🧑💻 Need help with #nfcore #nextflow #bioinformatics pipelines, running or developing? We are merging the 🌍 Eur/M.E./Afr and the 🌎 Americas weekly helpdesk. Please join our nf-core maintainers, this Thursday at 14:30 CET | 08:30 ET on play.workadventu.re/@/nf-core/nf... 011