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Mahesh Binzer-Panchal

@arcane-mahesh.bsky.social
178 followers 397 following 33 posts

Bioinformatician at the National Bioinformatics Infrastructure Sweden ( NBIS ) and SciLifeLab. I focus on de novo genome assembly, and pipeline development. #ReproducibleResearch with #Nextflow and #Quarto. #OpenScience github.com/mahesh-panchal

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Mahesh Binzer-Panchal @arcane-mahesh.bsky.social · 02/10/2026
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 20/08/2026
nf-core/genomeqc: a best-practice pipeline for comparing genome and assembly quality www.biorxiv.org/content/10.64898/20…
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nf-core @nf-co.re · 04/08/2026
Pipeline release! nf-core/seqsubmit v1.0.0 - 1.0.0! Please see the changelog: github.com/nf-core/seqsubmit/releas…
github.com
Release 1.0.0 · nf-core/seqsubmit
Initial release of nf-core/seqsubmit Added The pipeline supports four submission modes via dedicated workflows: mags — Metagenome Assembled Genomes submission (GENOMESUBMIT) bins — Metagenomic bin...
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Nextflow @nextflow.io · 29/05/2026
Become a Nextflow Ambassador in 2026!🌍 The ambassador program recognizes dedicated volunteers who contribute their time and expertise to foster collaboration & knowledge sharing across the Nextflow community. Applications close June 14, so don't wait! Apply now: hubs.la/Q04jlhr-0
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Phil Ewels @ewels.bsky.social · 13/05/2026
My talk from the #NextflowSummit is on YouTube! youtu.be/LbA_d4oOpDQ I talked about my recent odyssey with AI-written software, including #RustQC, rewrites.bio, Trim Galore and a FastQC rust rewrite 👀 This was honestly one of my favourite talks to date. I hope it's interesting for folks 😊
youtu.be
Phil Ewels: Bioinformatics in the agentic age: Practical tips learnt from RustQC and rewrites.bio
YouTube video by Nextflow
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Mahesh Binzer-Panchal @arcane-mahesh.bsky.social · 05/05/2026
10 year streak
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Katharina Hoff @katharinahoff.bsky.social · 29/04/2026
Post 1/2 Our new preprint is out! 🧬 We’ve extended #Tiberius for accurate ab initio gene prediction across the eukaryotic tree, including Plants, Fungi, Insects, and Diatoms. doi.org/10.64898/202...
doi.org
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Seqera @seqera.io · 23/04/2026
In the run up to #NextflowSummit, we wanted to shoutout to all 143 of our #Nextflow Ambassadors.🌍 The Ambassadors have such a big impact growing the Nextflow community, mentoring new users, creating training materials, and pushing the boundaries of what's possible.👏
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Natalie Cooper @nhcooper123.bsky.social · 25/03/2026
Hi all. I am very excited that after 6 years I finally got my phylogenetic comparative methods book and online exercises online. Feel free to use and share. The book is here: nhcooper123.github.io/pcm-primer/. Note that it is not finished, we had to abandon it before the sunk costs fallacy broke us
nhcooper123.github.io
Phylogenetic Comparative Methods
Phylogenetic Comparative Methods
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Jon Udell @jonudell.bsky.social · 12/03/2026
Nothing requires us to cede autonomy to our freakishly talented LLM assistants. We direct their efforts, and they learn from us. As we do the work they wield tools on our behalf. We can, if we choose, learn from them how best to use those tools, even as we often delegate the use to them.
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Mahesh Binzer-Panchal @arcane-mahesh.bsky.social · 10/03/2026
I finally fixed a few things in my Nextflow daisy chaining proof of concept and added a couple others. github.com/mahesh-panch.... Thanks to the Seqera team for spotlighting it in a recent podcast. seqera.io/podcasts/epi...
github.com
GitHub - mahesh-panchal/nf-cascade: A proof of concept daisy-chaining Nextflow workflows
A proof of concept daisy-chaining Nextflow workflows - mahesh-panchal/nf-cascade
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phy_papers @phypapers.bsky.social · 28/02/2026
OrthoGarden: a Pipeline for Propagating Phylogenetic Trees for Non-Model Organisms from Short Reads and de novo Genome Assemblies pubmed.ncbi.nlm.nih.gov/41755752
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Wei Shen 沈 伟 @shenwei356.bsky.social · 27/02/2026
Can't wait to release a 10-year-old birthday version for SeqKit! - 10 years - 2 papers, 3500 citations - 20 contributors - 40 subcommands - 880 commits - 500 issues - 685.5K Bioconda total downloads Thank you all, dear contributors and users! I'll keep maintaining it. github.com/shenwei356/s...
github.com
Release SeqKit v2.13.0 (10-year-old birthday version) · shenwei356/seqkit
Changelog SeqKit is 10 years old! SeqKit v2.13.0 - 2026-02-28 seqkit: add support for reading and writing LZ4 compression format. new command: seqkit sample2: improved seqkit sample by @stahiga....
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Anna Niehues @anna-niehues.bsky.social · 26/02/2026
Keeping your research software metadata in sync across repositories and registries just got easier. We’ve developed a bidirectional bridge between GitHub and bio.tools, helping you keep metadata up to date automatically. Check out our BioHackrXiv preprint: doi.org/10.37044/osf...
doi.org
OSF
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Zamin Iqbal @zaminiqbal.bsky.social · 25/02/2026
@wytamma.bsky.social 's WASM tools have transformed my experience of teaching Python to first year undergraduate biologists this year. Since last year, I've been teaching ~400 undergrads how to code (functions, lists, dictionaries, loops) over (one hour intro lecture +) two 2-hour practicals. 1/n
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Boas Pucker @bpucker.bsky.social · 25/02/2026
Are you passionate about computational biology and the evolution of specialized plant metabolism? More details and contact information: www.izmb.uni-bonn.de/en/pbb/conta... #Bioinformatics #Genomics #ResearchInGermany @puckerlab.bsky.social
Are you passionate about computational biology and the evolution of specialized plant metabolism?

We invite highly motivated and experienced students and early-career researchers to join our group in Bonn for a visiting research stay. This is a great opportunity to gain hands-on experience, exchange ideas, and work in a collaborative and supportive scientific environment with excellent computational resources.

We especially welcome colleagues with prior research experience in bioinformatics, phylogeny, evolutionary biology, or comparative genomics, and a strong interest in plant metabolism. Master’s students and candidates looking to strengthen their research profile are strongly encouraged to reach out.

If you are proactive, curious, and eager to conduct your own research project, we would love to hear from you.

More details and contact information:
https://www.izmb.uni-bonn.de/en/pbb/contact#EBPCM

#ComputationalBiology #Bioinformatics #EvolutionaryBiology #ComparativeGenomics #ResearchOpportunity #EarlyCareerResearchers
#PhDOpportunity #ScientificCollaboration #ResearchInGermany
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Ashley Juavinett, PhD @ashleyjuavinett.bsky.social · 24/02/2026
This paper started as an exchange here in late 2024 and evolved over the next year into a tidy set of recommendations for labs hoping to build more collaborative coding communities. 🎉 Would love to hear if any of these (really not so "simple") rules resonate with you, and what else you've tried.
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James Ferguson @psy-fer.bsky.social · 22/02/2026
Building a new plotting library in pure Rust. Making themes and colourblind mode available on every plot type from day 1. What other accessibility options can I add?
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BF Francis Ouellette @bffo.bsky.social · 24/02/2026
From @sciencebanshee.bsky.social @shen4brains.bsky.social @analog-ashley.bsky.social & colleagues in @plos.org #Computational #Biology | Ten simple rules for building a collaborative #coding #culture | #Education #Bioinformatics #PLOSCBTSR #OpenScience 🧬 🖥️ 🧪🔓 ⬇️ journals.plos.org/ploscompbiol...
journals.plos.org
Ten simple rules for building a collaborative coding culture
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Stephen Turner @stephenturner.us · 23/02/2026
Ten common misconceptions about Galaxy (and why they are wrong!) journals.plos.org/ploscompbiol...
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Open Sustainable Technology @opensustaintech.bsky.social · 23/02/2026
We welcome a new project to OpenSustain.tech #climate #sustainability #opensource #opensustain #openscience github.com/nextflow-io/...
github.com
GitHub - nextflow-io/nf-co2footprint: A Nextflow plugin to estimate the CO₂ footprint of pipeline runs.
A Nextflow plugin to estimate the CO₂ footprint of pipeline runs. - nextflow-io/nf-co2footprint
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Titus Brown @titus.idyll.org · 22/02/2026
Metax looks really nice for taxonomic profiling: www.biorxiv.org/content/10.6...
biorxiv.org
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 21/02/2026
American professors, who wants to come to Oxford for a year or two? Get in quick - deadline soon. www.balliol.ox.ac.uk/vacancy-geor...
balliol.ox.ac.uk
Vacancy - George Eastman Visiting Professorship
Vacancy - George Eastman Visiting Professorship The University invites expressions of interest in the George Eastman Visiting Professorship for the academic years 2026/2027 and 2027/2028, in an area
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Stephen Turner @stephenturner.us · 19/02/2026
Interesting post on electricity and water use from AI agents from @simonpcouch.com: www.simonpcouch.com/blog/2026-01...
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Camille Marchet ⚡ @camillemrcht.bsky.social · 19/02/2026
Were you aware that these are available for the community: - an efficient fasta/q parser in Rust - a quick rolling hash library - a minimizer library All in Rust 🦀
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Titus Brown @titus.idyll.org · 18/02/2026
sketch directly from URLs (including esp GenBank ;) github.com/sourmash-bio...
github.com
GitHub - sourmash-bio/sourmash_plugin_directsketch
Contribute to sourmash-bio/sourmash_plugin_directsketch development by creating an account on GitHub.
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Thomas Germain @thomasgermain.bsky.social · 18/02/2026
I got a tip that all over the world, people are using a dead-simple hack to manipulate AI behavior. It turns out changing what AI tells other people can be as easy as writing a blog post *on your own website* I didn’t believe it, so I decided to test it myself www.bbc.com/future/artic...
bbc.com
I hacked ChatGPT and Google's AI – and it only took 20 minutes
I found a way to make AI tell you lies – and I'm not the only one.
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BF Francis Ouellette @bffo.bsky.social · 18/02/2026
From @stephenturner.us | Rubrics, Not Vibes: Consistency as a Feature in Peer Review with AI | 🧪 #AI #OpenScience #PeerReview #Grants #Publications #PairedEnds ⬇️ blog.stephenturner.us/p/rubrics-no...
blog.stephenturner.us
Rubrics, Not Vibes: Consistency as a Feature in Peer Review with AI
Responsibly using AI for a structured first pass manuscript / grant proposal review can reduce reviewer variance while keeping human judgment central. Bonus: a prompt I use for my own draft proposals.
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Rob Patro @robp.bsky.social · 17/02/2026
How would you design a *multithreaded*, *concurrent* & *dynamic* hash table if you are focused specifically on common k-mer workloads, where streaming query & insertion are common? Jamshed, Prashant and I explore this in kache-hash, a cache-friendly k-mer hash table! www.biorxiv.org/content/10.6...
biorxiv.org
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Cat Hicks @grimalkina.bsky.social · 15/02/2026
Key to efficient learning is realizing how we ACTUALLY learn, not just what FEELS like learning. I wrote a Claude Skill for some friends to help them think about this and they've liked it -- see Principles for some directions you could explore github.com/DrCatHicks/l...
github.com
GitHub - DrCatHicks/learning-opportunities: A Claude Code skill for deliberate skill development during AI-assisted coding
A Claude Code skill for deliberate skill development during AI-assisted coding - DrCatHicks/learning-opportunities
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ELIXIR Europe @elixir-europe.org · 16/02/2026
📣 BioHackathon 2026 will be held on 9-13 November 2026 in Barcelona, Spain 🇪🇸! Call for project proposals will open on 16 March and close on 15 April at midnight. More information on project proposal scopes: loom.ly/m6hEBcM Check the #BioHackEU25 highlights: loom.ly/AfKwtZA
biohackathon-europe.org
BioHackathon Europe
Find out about the 2026 BioHackathon Europe, where hackers get together to make life science research easier.
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Rob Patro @robp.bsky.social · 15/02/2026
I’ve written a post about my recent experiences (successes) with AI coding models; the experiences that caused me to re-evaluate my initial judgements, the surprise I had at what can be accomplished, & some fears I have about these tools. Discussion welcome! combine-lab.github.io/blog/2026/02...
combine-lab.github.io
COMBINE-lab - The skeptic’s guide to generative AI assisted coding
An easy-to-use, flexible website template for labs, with automatic citations, GitHub tag imports, pre-built components, and more.
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Sébastien Guizard @bioinformaticus.bsky.social · 12/02/2026
I'm using #Nexflow almost daily. It is such a time saviour for analysis by suppressing job management. Here is the Hello-Nextflow playlist for those who want to join the Nexflow family. youtube.com/playlist?lis...
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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 09/02/2026
Fun news! @gcbias.bsky.social and I are teaching a 2-week online population genetics workshop this summer to raise money for the Center for Population Biology at UC Davis. We're trying to gauge interest -- please fill this out if you might be interested! And please share broadly!
docs.google.com
Davis Summer Population Genomics Program
Want to learn population genetics? Please fill out this form to indicate your potential interest in a 2-week intensive online summer population genetics course taught by Jeffrey Ross-Ibarra and Graham...
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Dr Elodie Chabrol @eloscicomm.bsky.social · 11/02/2026
🔬 C'est la Journée des femmes et filles de science ! #FemmesEnSciences #11février Envie de découvrir (ou faire découvrir) des femmes scientifiques ? J'ai rassemblé plein de ressources ici ⬇️ www.linkedin.com/pulse/envie-... Et mon starter pack de chercheuses sur bluesky go.bsky.app/TBEzKC
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ERGA - European Reference Genome Atlas @ergabiodiv.bsky.social · 21/01/2026
#ERGAReads | On the path to reference genomes for all biodiversity: laboratory protocols & lessons learned from processing over 2,000 species in the Sanger Tree of Life 🔗 academic.oup.com/gigascience/... @sangerinstitute.bsky.social @ebpgenome.bsky.social
academic.oup.com
On the path to reference genomes for all biodiversity: laboratory protocols and lessons learned from processing over 2,000 species in the Sanger Tree of Life
Abstract. Since its inception in 2019, the Tree of Life programme at the Wellcome Sanger Institute has released high-quality, chromosomally resolved refere
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Nextflow @nextflow.io · 20/01/2026
Nextflow Ambassador Nour Mahfel shares her journey from complete beginner to @nf-co.re contributor with support from @seqera.io. Learn how she shifted her mindset to think in dataflow, upstream modules, and embrace working in the open.📚 hubs.la/Q03_gcw_0
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nf-core @nf-co.re · 17/01/2026
New blog post! Running nf-core pipelines on ARM nf-co.re/blog/2026/arm-pipelines
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Stephen Turner @stephenturner.us · 18/01/2026
nf-core/crisprseq: a versatile pipeline for comprehensive analysis of CRISPR gene editing and screening assays academic.oup.com/nargab/artic... 🧬🖥️🧪 github.com/nf-core/cris...
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Heng Li @lh3lh3.bsky.social · 06/01/2026
Now published in Algorithms for Molecular Biology: link.springer.com/article/10.1.... Key message: a tiny CNN model with 7k parameters can capture main splice signals across vertebrates+insect and halves the minimap2 & miniprot junction error rate. I always use this new feature now.
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CATALYST Project @catalyst-reproducibility.eu · 18/12/2025
🎉 The full TIER2 Reproducibility Training Course is now available on OpenPlato. 💡 It provides researchers, publishers, and funders with both theoretical foundations and practical tools to support reproducible research practices. 🔎 Explore it here: openplato.eu/login/index....
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rogier kievit @rogierk.bsky.social · 18/12/2025
I've used Lavaan almost every (work)day for 15 years, but this open source labour of love has never received proper institutional support. I'm delighted to be a small part of an 1.5M OpenScienceNL award, led by Jorgensen, to completely revamp and futureproof Lavaan www.openscience.nl/en/news/45-p...
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James Fellows Yates @jfy133.genomic.social.ap.brid.gy · 11/12/2025
🎉 Huge shout out to everyone who instructed and participated in yesterday's online Meta-*omics #Nextflow Pipeline Community Exhibition Day! 🧑‍🏫 Over 9 hours, we had 15 different pipelines demo'd by their lead developers, and giving an international cohort of […] [Original post on genomic.social]
Slide containing text:

Meta-*omics Nextflow pipeline community exhibition day

Organised by James Fellows Yates

Supported by NFDI4Microbiota, Nextflow Ambassador program, and deNBI
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Mile Sikic @msikic.bsky.social · 11/12/2025
I’m recruiting a postdoc to work on algorithms for cancer genome reconstruction. We have access to a rich set of tumour samples sequenced across multiple technologies. If interested, feel free to DM. Please share.
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Mahesh Binzer-Panchal @arcane-mahesh.bsky.social · 06/12/2025
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Duke University School of Medicine @dukemedschool.bsky.social · 04/12/2025
Researchers say they’ve uncovered a key pathway behind age-related muscle loss. The surprising part: exercise helps reset the cellular system that keeps muscles young. 🔗 Read more: medschool.duke.edu/news/why-muscles… #AcademicSky #MedSky
Two senior adults jogging happily in a park with trees in the background.
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Hasindu Gamaarachchi @hasindu2008.bsky.social · 04/12/2025
Cornetto v0.2.0 is now released for using programmable selective nanopore sequencing for genome assembly. GitHub: github.com/hasindu2008/... Paper: nature.com/articles/s41... Datasets: hasindu2008.github.io/cornetto/doc... ... and a banner made by Ira Deveson referring to ‘no boring bits’.
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Wellcome Sanger Institute @sangerinstitute.bsky.social · 04/12/2025
The Sanger Prize 2026 is open for applications. A fully funded three-month placement for undergraduate students from low and middle-income countries. 🔗 Apply now: www.sanger.ac.uk/about/study/... 📅 The closing date for applications: 9th January 2026 at 5pm GMT
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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nf-core @nf-co.re · 03/12/2025
🧑‍💻 Need help with #nfcore #nextflow #bioinformatics pipelines, running or developing? We are merging the 🌍 Eur/M.E./Afr and the 🌎 Americas weekly helpdesk. Please join our nf-core maintainers, this Thursday at 14:30 CET | 08:30 ET on play.workadventu.re/@/nf-core/nf...
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