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Sébastien Guizard

@bioinformaticus.bsky.social
129 followers 778 following 32 posts

Do some biology related stuff with computers

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Reposted by Sébastien Guizard
GLITCH @glitchprod.com · 21/09/2026
Once upon a time...
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Charlotte Walker @charlottewalker.bsky.social · 28/10/2023
Someone sent me this meme about peer reviewer comments and it is 👌🏻 #PhDSky #AcademicSky
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Joseph Cox @josephcox.bsky.social · 17/08/2026
New from 404 Media: we solved which AI company is buying massive shipments of rare books, scanning and destroying them to train AI. We put an Apple AirTag in a rare book, followed it. It ended up at an Amazon facility. Its logo is a dinosaur ripping through a book www.404media.co/we-tracked-a...
404media.co
We Tracked a Shipment of Rare Books. It Ended at an Amazon AI Training Facility
We placed a tracking device in a shipment of rare books to see which AI company was buying it, and found an Amazon facility where Amazon scans and destroys books.
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Isabella Velásquez @ivelasq3.bsky.social · 03/08/2026
Join us tomorrow on the Data Science Lab where the awesome @richmeister.bsky.social will demonstrate live how to build automated validation pipelines and automated data reports with pointblank (mostly #RStats but some #python too!)! See you there: pos.it/dslab
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BioFAIR @biofair.bsky.social · 20/07/2026
🎙️ Episode 2 of the BioFAIR Community Podcast is live! Host Sam Haynes is joined by Nicola Soranzo, Robert Andrews & Evan Troendle to discuss the unique FAIR challenges they're tackling to improve the UK's life sciences infrastructure. 🎧 Listen here: biofair.uk/biofair-comm...
biofair.uk
BioFAIR Community Podcast - BioFAIR
Advancing Open Science, One Conversation at a Time. Welcome to The BioFAIR Community Podcast, your inside look at the people, tools, and ideas transforming how data is managed across the UK life scien...
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Tricia Dearborn @triciadearborn.bsky.social · 20/07/2026
Emily Bender and Nanna Inie: "all LLM output is probabilistically produced synthetic text". AI is not "intelligent". The chatbot does not have a clue what it just said to you. It does not *understand* the text it generates. So here's how to talk about it without making it sound like a living being
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nf-core @nf-co.re · 23/06/2026
Pipeline release! nf-core/differentialabundance v2.0.0 - v2.0.0 - 2026-06-23! Please see the changelog: github.com/nf-core/differentialabun…
github.com
Release v2.0.0 - 2026-06-23 · nf-core/differentialabundance
What's Changed Template update for nf-core/tools v2.14.1 by @WackerO in #273 Show >10 contrasts in report by @pinin4fjords in #272 Fix pagination on samples table by @pinin4fjords in #274 Fix gpro...
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Crystal Lewis @cghlewis.bsky.social · 17/06/2026
Using headers at the start of your code files provides a helpful introduction to your project. One way you can standardize this information is through code snippets in R! Once the snippet is created and named ("header" in this case), just enter the name and press tab and voila!
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Sébastien Guizard @bioinformaticus.bsky.social · 16/06/2026
@anthropic.com I think I might have offended your model xD
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Wellcome Sanger Institute @sangerinstitute.bsky.social · 22/05/2026
Scientists have developed a new tool that makes bird genomes faster and easier to assemble — including tiny pieces of DNA that are usually missed. 🐦‍⬛ The new tool, known as MicroFinder, could help improve research into bird evolution, biodiversity and conservation. 👇 bit.ly/4wG023C
sanger.ac.uk
New tool helps accurately assemble notoriously difficult bird genomes
MicroFinder can be used to assemble bird genomes much quicker and more accurately than ever before.
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Sébastien Guizard @bioinformaticus.bsky.social · 04/06/2026
@gooseworx.bsky.social Ready for the last episode @ the Dominion in Edinburgh!
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Earlham Institute @earlhaminst.bsky.social · 13/03/2026
Be part of a supportive and engaged community of #singlecell and #spatial scientists! 🧬💻🔎 Early-bird registration is open for the Norwich Single-Cell and Spatial Symposium! Discover the latest methods across diverse living systems. 🌱🧠🐟️ buff.ly/2KvQ3Zv @uniofeastanglia.bsky.social #EISingleCell26
Poster advertising the Norwich Single-Cell and Spatial Symposium. Black background with a red microscopy image of plant cells filling the right side. Event subtitle: “Novel applications of single-cell and spatial technologies across plant and microbe, animal, and health and disease research.” Date and venue highlighted in pink: 8–9 July 2026, Earlham Institute, Norwich, UK. Photos of four keynote speakers with names and affiliations: Ang Li (University of Oxford), Arnau Sebé-Pedrós (Centre for Genomic Regulation), Tatsuya Nobori (The Sainsbury Laboratory), and Jeffrey Moffitt (Harvard Medical School and Boston Children’s Hospital). List of invited speakers follows, Min-Yao Jhu, (University of Cambridge),
Christos Proukakis (UCL & Royal Free NHS Trust), Alina Kurjan (University of Oxford & Entelo Bio), and Ava Khamseh, (Institute of Cancer & Genetics, University of Edinburgh)
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Dr Pyviv @pyviv.bsky.social · 14/05/2026
Mediapart parle du problème des ZRR avec un cas de refus d'une postdoc porté devant le tribunal administratif. www.mediapart.fr/journal/fran...
mediapart.fr
À Bordeaux, une chercheuse engagée pour l’écologie se voit interdite de labo
De plus en plus de centres de recherche sont soumis à un régime administratif spécial, qui conditionne leur accès à une autorisation. Les refus – jamais motivés – sont de plus en plus nombreux.
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Defakator (Officiel) 🧆 @defakator.bsky.social · 10/05/2026
Le "ministère de la guerre" US publie les "UAP files" (UAP=Unidentified Aerial Phenomena, autrement dit les PAN, autrefois appelés OVNIs). Par exemple, cette photo de la mission Apollo 12 avec des "zones d'intérêt" signalées dans le ciel lunaire ! Regardons d'un peu plus près. [1/8]
Dans la photo AS12-46-6849 de la mission Apollo-12, le ministère de la guerre a encadré et grossi cinq artefacts dans le ciel Lunaire, désignés comme "zones d'intérêt" de 1 à 5.
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Kai Blin @kblin.bsky.social · 09/04/2026
I'm not looking forward to a future where all the tools are being vibe-rewritten into languages people don't want to learn. Who will maintain all this? The original maintainers won't. It's not the language they were comfortable with. Does the prompter understand the tool well enough?
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Carlos Scheidegger @cscheid.net · 06/04/2026
And another Quarto announcement; I've alluded to it before, but we're making it "official". We've started work on Quarto 2. The blog post has an overview: quarto.org/docs/blog/po... We'll share more in future blog posts, but here's what you can expect from the Quarto 2 dev effort: (1/)
quarto.org
What’s next: Quarto 2 – Quarto
We’ve started working on quarto-dev/q2, a full rewrite of Quarto in Rust.
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Katie Mack @astrokatie.com · 05/04/2026
We are so, so small. #Artemis
Looking through one of the four windows of the Orion spacecraft, a tiny crescent Earth is illuminated against the blackness of space and grows smaller as the crew journeys closer to the Moon. Part of the window edge is visible; the rest is darkness. [Alt-text slightly revised from ESA/NASA version]
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Nick Leigh @niche-leigh.bsky.social · 02/04/2026
New tool from the lab...check out Novabrowse: An interactive and customizable tool for interpreting BLAST results in genomic context! www.biorxiv.org/content/10.6... Does your favorite gene seems to be missing from your species of interest? Are you sure? 🧵👇 1/n
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Phil Ewels @ewels.bsky.social · 02/04/2026
Super excited to be launching two things today: #RustQC 🦀🧬 and rewrites.bio 🚀 I used AI to rewrite 15 RNA-seq QC tools into a single Rust binary (I've never written any Rust). It ended up being over 60x faster. Here's the story 🧵 seqeralabs.github.io/RustQC/
seqeralabs.github.io
Welcome to RustQC
Fast quality control tools for sequencing data, written in Rust.
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Sébastien Guizard @bioinformaticus.bsky.social · 26/03/2026
Github now use your interaction with copilot to train their models, unless you disable this feature. Here is how to do: Go to GitHub Account Settings > Select Copilot Settings > In Privacy, Set Allow GitHub to use my data for AI model training to "Disable" Don't work for free.
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#SingleCell preprints @prepub-singlecell.bsky.social · 19/03/2026
Integration of large, complex single-cell datasets with Harmony2 #SingleCell 🧪🧬🖥️ www.biorxiv.org/content/10.64898/20…
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Earlham Institute @earlhaminst.bsky.social · 09/03/2026
New for 2026, register your interest for our course 'Single-cell long-read bioinformatics: from data generation to visualisation', providing comprehensive end-to-end training on how to perform and analyse data from #longread #singlecell #RNA-seq experiments. 📅 17-19 November 2026
buff.ly
Single-cell Long-read Bioinformatics: from Data Generation to Visualisation
Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation
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Alejandro Montenegro @aemonten.bsky.social · 01/03/2026
"Here, we present SPAtial Cell Exploration (SPACE), a spatial CRISPR screening platform that integrates whole-transcriptome profiling (~18,000 genes), multiplexed protein detection (~68 markers), and CRISPR perturbation mapping at subcellular resolution" www.biorxiv.org/content/10.1...
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Sébastien Guizard @bioinformaticus.bsky.social · 27/02/2026
Amazing music, Amazing animation, thanks Gorillaz! youtu.be/ucRulNQsuYQ?...
youtu.be
Gorillaz - The Mountain, The Moon Cave and The Sad God
YouTube video by Gorillaz
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Isabella Velásquez @ivelasq3.bsky.social · 23/02/2026
I'm beyond excited for tomorrow's Data Science Lab with @davisvaughan.bsky.social! dplyr 1.2.0 is now out. There are many new functions in this release, and you will see them in action, live. You won't want to `filter_out()` this info 😉 Join us, we can't `replace_*` you 🧡 pos.it/dslab
Hello, dplyr 1.2.0! Join us with Davis Vaughan to explore new functions! Tuesday, Feb 24 at 12pm ET pos.it/dslab
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Stephen Turner @stephenturner.us · 16/02/2026
Creating Polished, Branded Documents with Quarto www.youtube.com/watch?v=sVMg... (R/Pharma 2025 #Rstats)
youtube.com
Creating Polished, Branded Documents with Quarto
Creating Polished, Branded Documents with Quarto - Isabella Velasquez Resources mentioned in the workshop: * Workshop site: https://bit.ly/rpharma2025-quarto * Exporting Quarto slides to PDF:…
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Stephen Turner @stephenturner.us · 17/02/2026
anndataR: converting single-cell data, from R to python and back tomsing1.github.io/blog/posts/a... #Rstats
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Stephen Turner @stephenturner.us · 16/02/2026
Pick a License, Not Any License doi.org/10.59350/98n... #Rstats #databs
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Rob Patro @robp.bsky.social · 16/02/2026
I feel it quite possible that those relying on AI from the very start may form a different skill set that will accelerate some software, but result in key regressions (without the expertise to address them) in other types. combine-lab.github.io/blog/2026/02... see the caveats section here…
combine-lab.github.io
COMBINE-lab - The skeptic’s guide to generative AI assisted coding
An easy-to-use, flexible website template for labs, with automatic citations, GitHub tag imports, pre-built components, and more.
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Sébastien Guizard @bioinformaticus.bsky.social · 13/02/2026
@gmilgram.bsky.social J'utilise la même méthode pour analyser mes séquences ADN. Je réserve une salle de réunion et je les fait défiler sur l'écran. 🤓
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Sébastien Guizard @bioinformaticus.bsky.social · 13/02/2026
Une fois encore, la science se fait piétiner. Heureusement que @gmilgram.bsky.social est la pour la défendre auprès du grand public youtu.be/2jdZbag21xQ?...
youtu.be
Nike et sa chaussure qui booste votre cerveau. Ah ? 😑
YouTube video by G Milgram
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Albert Vilella, PhD. @albertvilella.bsky.social · 12/02/2026
#bioinformatics #statistics #memes #bluesci
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Sébastien Guizard @bioinformaticus.bsky.social · 12/02/2026
I'm using #Nexflow almost daily. It is such a time saviour for analysis by suppressing job management. Here is the Hello-Nextflow playlist for those who want to join the Nexflow family. youtube.com/playlist?lis...
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Acermendax @acermendax.bsky.social · 11/02/2026
Une annonce tonitruante sur un remède au cancer aurait-elle été faite sans vérification de la qualité de la publication ?
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Cédric Scherer @cedricscherer.com · 11/02/2026
I just opted out of a workshop with a heavy heart when I learned it's a collab with DataCamp. No matter what, I'll maintain my boycott — why? Here is a detailed overview: dnlmc.medium.com/dont-use-dat... There are soooo many other options that value you, the community, and the instructors!
dnlmc.medium.com
Don’t use DataCamp
A timeline of transgressions & community response
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charpentiermyriam.bsky.social @charpentiermyriam.bsky.social · 11/02/2026
My lab at the JIC is recruiting 3 PDRA: 🔹 Bioinformatics / AI 🔹 Molecular Biology / Genetics 🔹 Proteomics Programme funded by the Novo Nordisk Foundation. 📅 Closing date: 27 February Apply via JIC website: www.jic.ac.uk/vacancies/ Please share with outstanding candidates. 🙏
jic.ac.uk
Postdoctoral Researcher (Charpentier Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.
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Adam Phillippy @aphillippy.bsky.social · 29/01/2026
New tool from @alexsweeten.bsky.social to find and classify all your satellites: "AniAnn's: alignment-free annotation of tandem repeat arrays using fast average nucleotide identity estimates" 📄 www.biorxiv.org/content/10.6... 📦 github.com/marbl/anianns
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Mujtaba Rahman @mijrahman.bsky.social · 22/01/2026
Emmanuel Macron’s softly-softly approach to Donald Trump is over, it appears. As you'll see below, the Elysée Palace has published a gif of Trump  labelled with one of the US president’s own favourite slurs: “Fake news”.  1/
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Olivier Simard-Casanova @o.simardcasanova.net · 22/01/2026
European senior diplomats are (indirectly) comparing Donald Trump to Adolf Hitler
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Smooth Dunk @smoothdunk2.bsky.social · 22/01/2026
[AI bubble bursts] billionaire tech bro: the stupid consumer did not understand it
3 panel comic

Panel 1: 
Orange Guy standing at a stall with a sign that says “Shit Sandwich, £500”
Pink Guy walks up to the stall, Orange Guy gestures excitedly at the sign.

Panel 2:
Pink Guy continues walking past the Shit Sandwich stall. The Orange Guy looks dejected

Panel 3: 
Orange Guy says “Wow. That guy can’t read”
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Olivier Simard-Casanova @o.simardcasanova.net · 12/01/2026
Opening Bluesky in the morning these days is basically a variation of thinking “what the hell did Trump do AGAIN” and spending a few minutes researching what actually happened (This is not a criticism of Bluesky, this is a criticism of Trump)
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Defakator (Officiel) 🧆 @defakator.bsky.social · 07/01/2026
A Minneapolis l'ICE a tué une manifestante anti-ICE. Elle était dans sa voiture, arrêtée en travers pour bloquer la route. 2 policiers lui disent de sortir, elle refuse et démarre pour s'en aller. Sans rouler vers eux... mais un policier tire à bout portant. Or, Trump raconte un autre récit. [1]
La voiture de la manifestante anti-ICE qui tente de partir. Elle ne fonce pas sur les agents de l'ICE, elle tente de contourner la voiture blanche arrêtée sur la droite mais sans foncer sur les policiers qui sont sur le côté du véhicule, debout. L'un des policiers tire à bout portant.
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Alex Music @alexmusicwrites.bsky.social · 07/01/2026
NEW: My research has found that 17 of the 200 highest-ranked U.S. colleges have removed references to gender identity, gender expression, and/or sexual orientation from their nondiscrimination policies. See the full list here: medium.com/prismnpen/to...
medium.com
Top U.S. Universities Are Quietly Removing LGBTQ+ Discrimination Protections
From the Ivy League to elite state schools, this list might surprise you
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Science Magazine @science.org · 06/01/2026
Evolution doesn’t always take thousands or millions of years. Sometimes it happens right before our eyes. Such is the case with the Anna’s hummingbird, a species that has undergone a dramatic transformation in a few generations, thanks to the advent of hummingbird feeders: scim.ag/3YMuQQu
Bird feeders have caused a dramatic evolution of California hummingbirds
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Defakator (Officiel) 🧆 @defakator.bsky.social · 06/01/2026
La soirée Twitch d'hier : "Defakador : c'est vous qui defakez sur les fakes !" est dispo en replay. youtu.be/KPG1Sct9juM
youtu.be
🧆 DefaKADOR #12 : Entraînement au defake - 05/01/2026
YouTube video by Defakator [Replays Twitch]
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European Conference on Computational Biology @eccb-europe.bsky.social · 05/01/2026
📣 Still 11 days to submit proposals for workshops and tutorials for #ECCB2026! Don't miss the opportunity to be an active part of one of Europe's leading conference in #Bioinformatics and #ComputationalBiology. Deadline: 16 January 2026 🔗 eccb2026.org/call-tutoria...
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Thijs J. G. Ettema 🦠🔬🇳🇱🇸🇪🇪🇺 @ettema.bsky.social · 05/01/2026
I have a postdoc position in metagenomic exploration available in my group. Candidates with documented experience in phylo & metagenomics and preferably with petabase-scale data mining and GLM workflows are encouraged to apply. Come join us! 🧬🦠💻 Please repost Apply here: www.wur.nl/en/vacancy/p...
wur.nl
Postdoctoral researcher Phylogenomics and metagenomics
Are you just as excited as we are about the fascinating world of microorganisms? Do you want to contribute to exploring and genomically characterize novel prokaryotic lineages? Do you have a PhD degre...
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Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 05/01/2026
Canadian officials are correct, and it’s truly a tragedy.
theguardian.com
Canadian officials say US health institutions no longer dependable for accurate information
Misinformation from the Trump administration is cited as fuelling Canadians’ concerns over childhood vaccinations
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Cameron Thrash @jcamthrash.bsky.social · 02/01/2026
Troubleshooting common errors in assemblies of long-read metagenomes www.nature.com/articles/s41... #jcampubs
nature.com
Troubleshooting common errors in assemblies of long-read metagenomes - Nature Biotechnology
Long-read sequence assemblies from metagenomes contain frequent errors.
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Arjun Raj @arjunraj.bsky.social · 30/12/2025
Blog post: Just quit Quitting projects in science is hard, but we should be doing a lot more of it. open.substack.com/pub/arjunraj...
open.substack.com
Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
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